Primary Site >> Colorectal Cancer

Gene >> DACH1

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Ref: Anticancer activity in murine and human tumor cell lines of bis(platinum) complexes incorporating straight-chain aliphatic diamine linker groups.
PMID: 1335074
Ref: Pilot study for preoperative administration of l-OHP to patients with advanced scirrhous type gastric cancer.
PMID: 9247019
Ref: [Chemotherapy of advanced colorectal cancers after failure of a treatment with fluoropyrimidine].
PMID: 9248091
Ref: [Oxaliplatin: the first DACH platinum in clinical practice].
PMID: 9295871
Ref: Cytotoxicity of two novel cisplatin analogues, (CPA)2Pt[DOLYM] and (DACH)Pt[DOLYM], to human cancer cells in vitro.
PMID: 10230505
Ref: Chemotherapy in elderly patients with colorectal cancer.
PMID: 11398873
Ref: Hepatic arterial continuous infusion (HACI) of oxaliplatin in patients with unresectable liver metastases from colorectal cancer.
PMID: 12820479
Ref: [Oxaliplatin neurotoxicity].
PMID: 16491518
Ref: Debio 0507 primarily forms diaminocyclohexane-Pt-d(GpG) and -d(ApG) DNA adducts in HCT116 cells.
PMID: 21968950
Ref: Revisiting [PtCl(2)(cis-1,4-DACH)]: an underestimated antitumor drug with potential application to the treatment of oxaliplatin-refractory colorectal cancer.
PMID: 22788918
Ref: Epigenetic regulation of DACH1, a novel Wnt signaling component in colorectal cancer.
PMID: 24149323
Ref: A comprehensive look at transcription factor gene expression changes in colorectal adenomas.
PMID: 24472434
Ref: East-west fusion-necrosis and apoptosis acting in concert by demethylcantharidin-integrated platinum complexes.
PMID: 24476313
Ref: Epigenetic silencing of DACH1 induces the invasion and metastasis of gastric cancer by activating TGF-beta signalling.
PMID: 24912879
Ref: A novel class of bis- and tris-chelate diam(m)inebis(dicarboxylato)platinum(IV) complexes as potential anticancer prodrugs.
PMID: 25032896
Ref: Suppression of DACH1 promotes migration and invasion of colorectal cancer via activating TGF-beta-mediated epithelial-mesenchymal transition.
PMID: 25778865
Ref: Oxaliplatin analogues with carboxy derivatives of boldine with enhanced antioxidant activity.
PMID: 25814916
Ref: Cytotoxicity-boosting of kiteplatin by Pt(IV) prodrugs with axial benzoate ligands.
PMID: 26775068
Ref: DNA binding properties, histidine interaction and cytotoxicity studies of water soluble ruthenium(ii) terpyridine complexes.
PMID: 26855406
Ref: Encapsulation of lipophilic kiteplatin Pt(iv) prodrugs in PLGA-PEG micelles.
PMID: 27094010
Ref: Synthesis, Characterization, and Cytotoxicity of the First Oxaliplatin Pt(IV) Derivative Having a TSPO Ligand in the Axial Position.
PMID: 27347942
Ref: Hydroxyapatite nanocrystals as a smart, pH sensitive, delivery system for kiteplatin.
PMID: 27397134
Ref: PtI2(DACH), the iodido analogue of oxaliplatin as a candidate for colorectal cancer treatment: chemical and biological features.
PMID: 28229139
Ref: MicroRNA-552 promotes tumor cell proliferation and migration by directly targeting DACH1 via the Wnt/beta-catenin signaling pathway in colorectal cancer.
PMID: 28927149
Ref: Anticancer activity of new imidazole derivative of 1R,2R-diaminocyclohexane palladium and platinum complexes as DNA fluorescent probes.
PMID: 29027501