Primary Site >> Liver Cancer

Gene >> CYR61

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Ref: Expression of Nov, CYR61 and CTGF genes in human hepatocellular carcinoma.
PMID: 11251312
Ref: Expressions of cysteine-rich61, connective tissue growth factor and Nov genes in hepatocellular carcinoma and their clinical significance.
PMID: 15526358
Ref: Expression of WISPs and of their novel alternative variants in human hepatocellular carcinoma cells.
PMID: 15650268
Ref: Dinucleotide repeats negatively modulate the promoter activity of Cyr61 and is unstable in hepatocellular carcinoma patients.
PMID: 15782120
Ref: Cyr61/CCN1 is a tumor suppressor in human hepatocellular carcinoma and involved in DNA damage response.
PMID: 17698398
Ref: Emodin inhibits the growth of hepatoma cells: finding the common anti-cancer pathway using Huh7, Hep3B, and HepG2 cells.
PMID: 19895793
Ref: Differential expression of Axl in hepatocellular carcinoma and correlation with tumor lymphatic metastasis.
PMID: 20635370
Ref: Cyr61/CCN1 is regulated by Wnt/beta-catenin signaling and plays an important role in the progression of hepatocellular carcinoma.
PMID: 22540002
Ref: The clinically used photosensitizer Verteporfin (VP) inhibits YAP-TEAD and human retinoblastoma cell growth in vitro without light activation.
PMID: 24837142
Ref: Expression of CCN family members correlates with the clinical features of hepatocellular carcinoma.
PMID: 25571929
Ref: The matricellular protein CCN1 suppresses hepatocarcinogenesis by inhibiting compensatory proliferation.
PMID: 26028023
Ref: YAP Subcellular Localization and Hippo Pathway Transcriptome Analysis in Pediatric Hepatocellular Carcinoma.
PMID: 27605415
Ref: CCN1/Cyr61 enhances the function of hepatic stellate cells in promoting the progression of hepatocellular carcinoma.
PMID: 29286082
Ref: EGFR-PI3K-PDK1 pathway regulates YAP signaling in hepatocellular carcinoma: the mechanism and its implications in targeted therapy.
PMID: 29449645
Ref: Ajuba inhibits hepatocellular carcinoma cell growth via targeting of beta-catenin and YAP signaling and is regulated by E3 ligase Hakai through neddylation.
PMID: 30041665
Ref: ATF3 inhibits the tumorigenesis and progression of hepatocellular carcinoma cells via upregulation of CYR61 expression.
PMID: 30376856