Primary Site >> Colorectal Cancer
Gene >> CYP3A5
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Ref: Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells. PMID: 8632764 |
Ref: Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxyvitamin D3. PMID: 9145912 Ref: The role of xenobiotic metabolizing enzymes in arylamine toxicity and carcinogenesis: functional and localization studies. PMID: 9202751 |
Ref: Expression of paclitaxel-inactivating CYP3A activity in human colorectal cancer: implications for drug therapy. PMID: 12237780 |
Ref: Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis. PMID: 15897573 |
Ref: Acquired resistance to the anticancer drug paclitaxel is associated with induction of cytochrome P450 2C8. PMID: 16753005 |
Ref: Genetic variability in CYP3A4 and CYP3A5 in primary liver, gastric and colorectal cancer patients. PMID: 17605821 Ref: Polymorphisms in the cytochrome P450 genes CYP1A2, CYP1B1, CYP3A4, CYP3A5, CYP11A1, CYP17A1, CYP19A1 and colorectal cancer risk. PMID: 17615053 Ref: Genotyping of CYP3A5 polymorphisms among Bulgarian patients with sporadic colorectal cancer and controls. PMID: 17992026 |
Ref: Irinotecan induces steroid and xenobiotic receptor (SXR) signaling to detoxification pathway in colon cancer cells. PMID: 21733184 |
Ref: CYP3A5*3 polymorphism and cancer risk: a meta-analysis and meta-regression. PMID: 23584898 |