Primary Site >> Colorectal Cancer
Gene >> CYP27B1
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Ref: 25-Hydroxyvitamin D(3)-1alpha-hydroxylase and vitamin D receptor gene expression in human colonic mucosa is elevated during early cancerogenesis. PMID: 11179736 |
Ref: Clonal differences in expression of 25-hydroxyvitamin D(3)-1alpha-hydroxylase, of 25-hydroxyvitamin D(3)-24-hydroxylase, and of the vitamin D receptor in human colon carcinoma cells: effects of epidermal growth factor and 1alpha,25-dihydroxyvitamin D(3). PMID: 12027461 Ref: Phytoestrogens regulate vitamin D metabolism in the mouse colon: relevance for colon tumor prevention and therapy. PMID: 12421875 |
Ref: Phytoestrogens and 17beta-estradiol influence vitamin D metabolism and receptor expression-relevance for colon cancer prevention. PMID: 12899537 Ref: Regulation of extrarenal vitamin D metabolism as a tool for colon and prostate cancer prevention. PMID: 12899539 Ref: Regulation of extrarenal synthesis of 1,25-dihydroxyvitamin D3--relevance for colonic cancer prevention and therapy. PMID: 14585316 |
Ref: Phytoestrogens and vitamin D metabolism: a new concept for the prevention and therapy of colorectal, prostate, and mammary carcinomas. PMID: 15113973 |
Ref: Colon-specific regulation of vitamin D hydroxylases--a possible approach for tumor prevention. PMID: 15905206 Ref: The Vitamin D endocrine system of the gut--its possible role in colorectal cancer prevention. PMID: 16081282 Ref: Vitamin D deficiency enhances the growth of MC-26 colon cancer xenografts in Balb/c mice. PMID: 16177194 Ref: Expression of vitamin D receptor and 25-hydroxyvitamin D3-1{alpha}-hydroxylase in normal and malignant human colon. PMID: 16214919 |
Ref: 1,25-Dihydroxyvitamin D and 25-hydroxyvitamin D--mediated regulation of TRPV6 (a putative epithelial calcium channel) mRNA expression in Caco-2 cells. PMID: 16362534 |
Ref: Chemopreventive efficacy of 25-hydroxyvitamin D3 in colon cancer. PMID: 17257827 Ref: CYP27A1 and CYP24 expression as a function of malignant transformation in the colon. PMID: 17875655 |
Ref: Genetic variation in calcium-sensing receptor and risk for colon cancer. PMID: 18843020 |
Ref: Chemoprevention of colorectal neoplasia by estrogen: potential role of vitamin D activity. PMID: 19139017 Ref: Regulation of the colonic vitamin D system for prevention of tumor progression: an update. PMID: 19450178 Ref: Expression of 25-hydroxyvitamin D-1alpha-hydroxylase (1alphaOHase, CYP27B1) splice variants in HaCaT keratinocytes and other skin cells: modulation by culture conditions and UV-B treatment in vitro. PMID: 19667162 Ref: Parallel elevation of colonic 1,25-dihydroxyvitamin D3 levels and apoptosis in female mice on a calcium-deficient diet. PMID: 19667171 Ref: Vitamin D related genes, CYP24A1 and CYP27B1, and colon cancer risk. PMID: 19706847 |
Ref: The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the "Fountain of Youth" to mediate healthful aging. PMID: 20227497 |
Ref: A randomized clinical trial of the effects of supplemental calcium and vitamin D3 on markers of their metabolism in normal mucosa of colorectal adenoma patients. PMID: 21084270 Ref: Colonic vitamin D metabolism: implications for the pathogenesis of inflammatory bowel disease and colorectal cancer. PMID: 21801808 Ref: Predicting ulcerative colitis-associated colorectal cancer using reverse-transcription polymerase chain reaction analysis. PMID: 21859567 |
Ref: Relative Expression of Vitamin D Hydroxylases, CYP27B1 and CYP24A1, and of Cyclooxygenase-2 and Heterogeneity of Human Colorectal Cancer in Relation to Age, Gender, Tumor Location, and Malignancy: Results from Factor and Cluster Analysis. PMID: 24213465 |
Ref: Prevention of preneoplastic lesions by dietary vitamin D in a mouse model of colorectal carcinogenesis. PMID: 22982628 Ref: CYP24A1 and CYP27B1 polymorphisms modulate vitamin D metabolism in colon cancer cells. PMID: 23423976 Ref: Serum vitamin D metabolites in colorectal cancer patients receiving cholecalciferol supplementation: correlation with polymorphisms in the vitamin D genes. PMID: 23456391 Ref: Increased copy-number and not DNA hypomethylation causes overexpression of the candidate proto-oncogene CYP24A1 in colorectal cancer. PMID: 23463632 |
Ref: Role of proinflammatory cytokines on expression of vitamin D metabolism and target genes in colon cancer cells. PMID: 24120915 Ref: Ex vivo culture of primary human colonic tissue for studying transcriptional responses to 1alpha,25(OH)2 and 25(OH) vitamin D. PMID: 24550213 Ref: Genetic variation in vitamin D-related genes and risk of colorectal cancer in African Americans. PMID: 24562971 Ref: Lack of associations between Vitamin D metabolism-related gene variants and risk of colorectal cancer. PMID: 24568525 |
Ref: Effects of supplemental vitamin D and calcium on normal colon tissue and circulating biomarkers of risk for colorectal neoplasms. PMID: 25597952 Ref: CYP24A1 and CYP27B1 Polymorphisms, Concentrations of Vitamin D Metabolites, and Odds of Colorectal Adenoma Recurrence. PMID: 26241700 |
Ref: 1,25(OH)2D3 Deficiency Induces Colon Inflammation via Secretion of Senescence-Associated Inflammatory Cytokines. PMID: 26790152 Ref: Vitamin D and colorectal cancer: molecular, epidemiological and clinical evidence. PMID: 27245104 Ref: Immunoglobulin E induces colon cancer cell apoptosis via enhancing cyp27b1 expression. PMID: 28078042 |
Ref: Genetic polymorphisms of vitamin D receptor (VDR), CYP27B1 and CYP24A1 genes and the risk of colorectal cancer. PMID: 28009432 Ref: Genetic polymorphisms of vitamin D metabolism genes and serum level of vitamin D in colorectal cancer. PMID: 28665452 Ref: Dietary factors and polymorphisms in vitamin D metabolism genes: the risk and prognosis of colorectal cancer in northeast China. PMID: 28821819 |