Primary Site >> Colorectal Cancer

Gene >> CYP26A1

  • 1998
  • 2006
  • 2014
  • 2016
  • 2017
Ref: Human retinoic acid (RA) 4-hydroxylase (CYP26) is highly specific for all-trans-RA and can be induced through RA receptors in human breast and colon carcinoma cells.
PMID: 9716180
Ref: Up-regulation of CYP26A1 in adenomatous polyposis coli-deficient vertebrates via a WNT-dependent mechanism: implications for intestinal cell differentiation and colon tumor development.
PMID: 16885356
Ref: Altered expression of multiple genes involved in retinoic acid biosynthesis in human colorectal cancer.
PMID: 24599561
Ref: The expression and prognostic significance of retinoic acid metabolising enzymes in colorectal cancer.
PMID: 24608339
Ref: Normalizing Microbiota-Induced Retinoic Acid Deficiency Stimulates Protective CD8(+) T Cell-Mediated Immunity in Colorectal Cancer.
PMID: 27590114
Ref: Restoring Retinoic Acid Attenuates Intestinal Inflammation and Tumorigenesis in APCMin/+ Mice.
PMID: 27638841
Ref: Meta-analysis of miRNA expression profiles for prostate cancer recurrence following radical prostatectomy.
PMID: 28651018