Primary Site >> Colorectal Cancer
Gene >> CYP24A1
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Ref: 25-hydroxy-vitamin d metabolism in human colon cancer cells during tumor progression. PMID: 11467853 |
Ref: Clonal differences in expression of 25-hydroxyvitamin D(3)-1alpha-hydroxylase, of 25-hydroxyvitamin D(3)-24-hydroxylase, and of the vitamin D receptor in human colon carcinoma cells: effects of epidermal growth factor and 1alpha,25-dihydroxyvitamin D(3). PMID: 12027461 Ref: Phytoestrogens regulate vitamin D metabolism in the mouse colon: relevance for colon tumor prevention and therapy. PMID: 12421875 |
Ref: Phytoestrogens and 17beta-estradiol influence vitamin D metabolism and receptor expression-relevance for colon cancer prevention. PMID: 12899537 Ref: Regulation of extrarenal vitamin D metabolism as a tool for colon and prostate cancer prevention. PMID: 12899539 Ref: Regulation of extrarenal synthesis of 1,25-dihydroxyvitamin D3--relevance for colonic cancer prevention and therapy. PMID: 14585316 |
Ref: Phytoestrogens and vitamin D metabolism: a new concept for the prevention and therapy of colorectal, prostate, and mammary carcinomas. PMID: 15113973 |
Ref: Colon-specific regulation of vitamin D hydroxylases--a possible approach for tumor prevention. PMID: 15905206 Ref: Promoter-, cell-, and ligand-specific transactivation responses of the VDRB1 isoform. PMID: 15992766 Ref: The Vitamin D endocrine system of the gut--its possible role in colorectal cancer prevention. PMID: 16081282 |
Ref: Expression of VDR and CYP24A1 mRNA in human tumors. PMID: 16180015 Ref: The retinoid X receptor ligand restores defective signalling by the vitamin D receptor. PMID: 16936639 |
Ref: Array CGH identifies distinct DNA copy number profiles of oncogenes and tumor suppressor genes in chromosomal- and microsatellite-unstable sporadic colorectal carcinomas. PMID: 17143621 Ref: Lithocholic acid can carry out in vivo functions of vitamin D. PMID: 17535892 Ref: CYP27A1 and CYP24 expression as a function of malignant transformation in the colon. PMID: 17875655 |
Ref: Reverse transcriptase inhibitors induce cell differentiation and enhance the immunogenic phenotype in human renal clear-cell carcinoma. PMID: 18351578 Ref: A novel SNP in a vitamin D response element of the CYP24A1 promoter reduces protein binding, transactivation, and gene expression. PMID: 18824104 Ref: Genetic variation in calcium-sensing receptor and risk for colon cancer. PMID: 18843020 Ref: RhoA-ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype, and Wnt pathway in colon cancer cells. PMID: 19015318 |
Ref: Chemoprevention of colorectal neoplasia by estrogen: potential role of vitamin D activity. PMID: 19139017 Ref: Regulation of the colonic vitamin D system for prevention of tumor progression: an update. PMID: 19450178 Ref: Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer. PMID: 19502595 Ref: Parallel elevation of colonic 1,25-dihydroxyvitamin D3 levels and apoptosis in female mice on a calcium-deficient diet. PMID: 19667171 Ref: Vitamin D related genes, CYP24A1 and CYP27B1, and colon cancer risk. PMID: 19706847 |
Ref: Curcumin: a novel nutritionally derived ligand of the vitamin D receptor with implications for colon cancer chemoprevention. PMID: 20153625 Ref: The effects of 1,25-dihydroxyvitamin D3 on colon cancer cells depend on RhoA-ROCK-p38MAPK-MSK signaling. PMID: 20223287 Ref: The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the "Fountain of Youth" to mediate healthful aging. PMID: 20227497 Ref: CYP24A1 splice variants--implications for the antitumorigenic actions of 1,25-(OH)2D3 in colorectal cancer. PMID: 20398751 |
Ref: A randomized clinical trial of the effects of supplemental calcium and vitamin D3 on markers of their metabolism in normal mucosa of colorectal adenoma patients. PMID: 21084270 Ref: Colonic vitamin D metabolism: implications for the pathogenesis of inflammatory bowel disease and colorectal cancer. PMID: 21801808 |
Ref: Regulation of CYP24 splicing by 1,25-dihydroxyvitamin D(3) in human colon cancer cells. PMID: 22068926 Ref: Relative Expression of Vitamin D Hydroxylases, CYP27B1 and CYP24A1, and of Cyclooxygenase-2 and Heterogeneity of Human Colorectal Cancer in Relation to Age, Gender, Tumor Location, and Malignancy: Results from Factor and Cluster Analysis. PMID: 24213465 |
Ref: Curcumin induces human cathelicidin antimicrobial peptide gene expression through a vitamin D receptor-independent pathway. PMID: 22841393 Ref: Epigenetic regulation of the 1,25-dihydroxyvitamin D3 24-hydroxylase (CYP24A1) in colon cancer cells. PMID: 22940288 Ref: Prevention of preneoplastic lesions by dietary vitamin D in a mouse model of colorectal carcinogenesis. PMID: 22982628 Ref: CYP24A1 and CYP27B1 polymorphisms modulate vitamin D metabolism in colon cancer cells. PMID: 23423976 Ref: Serum vitamin D metabolites in colorectal cancer patients receiving cholecalciferol supplementation: correlation with polymorphisms in the vitamin D genes. PMID: 23456391 Ref: Increased copy-number and not DNA hypomethylation causes overexpression of the candidate proto-oncogene CYP24A1 in colorectal cancer. PMID: 23463632 Ref: CYP24A1 inhibition facilitates the anti-tumor effect of vitamin D3 on colorectal cancer cells. PMID: 23674869 Ref: Genetic predictors of circulating 25-hydroxyvitamin d and risk of colorectal cancer. PMID: 23983240 |
Ref: Role of proinflammatory cytokines on expression of vitamin D metabolism and target genes in colon cancer cells. PMID: 24120915 Ref: Ex vivo culture of primary human colonic tissue for studying transcriptional responses to 1alpha,25(OH)2 and 25(OH) vitamin D. PMID: 24550213 Ref: Genetic variation in vitamin D-related genes and risk of colorectal cancer in African Americans. PMID: 24562971 |
Ref: Targeted delivery of 1,25-dihydroxyvitamin D3 to colon tissue and identification of a major 1,25-dihydroxyvitamin D3 glycoside from Solanumglaucophyllum plant leaves. PMID: 25445916 Ref: CYP24A1 and CYP27B1 Polymorphisms, Concentrations of Vitamin D Metabolites, and Odds of Colorectal Adenoma Recurrence. PMID: 26241700 Ref: Differential antitumor effects of vitamin D analogues on colorectal carcinoma in culture. PMID: 26260259 |
Ref: Impact of CYP24A1 overexpression on growth of colorectal tumour xenografts in mice fed with vitamin D and soy. PMID: 26238339 Ref: CYP24A1 variant modifies the association between use of oestrogen plus progestogen therapy and colorectal cancer risk. PMID: 26766742 Ref: Synthesis and evaluation of vitamin D receptor-mediated activities of cholesterol and vitamin D metabolites. PMID: 26774929 Ref: CYP24A1 is a potential biomarker for the progression and prognosis of human colorectal cancer. PMID: 26997443 Ref: Vitamin D and colorectal cancer: molecular, epidemiological and clinical evidence. PMID: 27245104 Ref: A role for the vitamin D pathway in non-intestinal lesions in genetic and carcinogen models of colorectal cancer and in familial adenomatous polyposis. PMID: 27768599 |
Ref: Genetic polymorphisms of vitamin D receptor (VDR), CYP27B1 and CYP24A1 genes and the risk of colorectal cancer. PMID: 28009432 Ref: Vitamin D Reduces Colitis- and Inflammation-Associated Colorectal Cancer in Mice Independent of NOD2. PMID: 28045548 Ref: Constitutively active RAS signaling reduces 1,25 dihydroxyvitamin D-mediated gene transcription in intestinal epithelial cells by reducing vitamin D receptor expression. PMID: 28104492 Ref: Genetic polymorphisms of vitamin D metabolism genes and serum level of vitamin D in colorectal cancer. PMID: 28665452 Ref: Association between CYP24A1 polymorphisms and the risk of colonic polyps and colon cancer in a Chinese population. PMID: 28811712 Ref: Dietary factors and polymorphisms in vitamin D metabolism genes: the risk and prognosis of colorectal cancer in northeast China. PMID: 28821819 |
Ref: CYP24A1 Inhibition Facilitates the Antiproliferative Effect of 1,25(OH)2D3 Through Downregulation of the WNT/beta-Catenin Pathway and Methylation-Mediated Regulation of CYP24A1 in Colorectal Cancer Cells. PMID: 30052060 Ref: miR-30a promoter variation contributes to the increased risk of colorectal cancer in an Iranian population. PMID: 30387187 |