Primary Site >> Colorectal Cancer
Gene >> CYP1B1
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Ref: Regulation of cytochrome P450 enzymes by aryl hydrocarbon receptor in human cells: CYP1A2 expression in the LS180 colon carcinoma cell line after treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin or 3-methylcholanthrene. PMID: 9783729 |
Ref: Detection of cytochrome P450 1B1 Bfr I polymorphism: genotype distribution in healthy German individuals and in patients with colorectal carcinoma. PMID: 10471075 |
Ref: Prenatal toxicity and lack of carcinogenicity of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) following transplacental exposure. PMID: 10828274 Ref: Differential sensitivity to lung tumorigenesis following transplacental exposure of mice to polycyclic hydrocarbons, heterocyclic amines, and lung tumor promoters. PMID: 11195466 |
Ref: Induction of CYP1A1, CYP1A2, and CYP1B1 mRNAs by nitropolycyclic aromatic hydrocarbons in various human tissue-derived cells: chemical-, cytochrome P450 isoform-, and cell-specific differences. PMID: 12107646 Ref: A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer. PMID: 12419832 |
Ref: Critical enhancer region to which AhR/ARNT and Sp1 bind in the human CYP1B1 gene. PMID: 12801909 Ref: Cytochrome P450 1B1 (CYP1B1) is overexpressed in human colon adenocarcinomas relative to normal colon: implications for drug development. PMID: 12813131 |
Ref: Soy protein isolate and protection against cancer. PMID: 15798082 Ref: Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis. PMID: 15897573 Ref: A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of colorectal cancer. PMID: 16006997 Ref: Ten polymorphisms of estrogen-metabolizing genes and a family history of colon cancer--an association study of multiple gene-gene interactions. PMID: 16202920 Ref: Using a combination of cytochrome P450 1B1 and beta-catenin for early diagnosis and prevention of colorectal cancer. PMID: 16289386 |
Ref: Case-only study of interactions between metabolic enzymes and smoking in colorectal cancer. PMID: 17603900 Ref: Polymorphisms in the cytochrome P450 genes CYP1A2, CYP1B1, CYP3A4, CYP3A5, CYP11A1, CYP17A1, CYP19A1 and colorectal cancer risk. PMID: 17615053 Ref: Combinations of cytochrome P450 gene polymorphisms enhancing the risk for sporadic colorectal cancer related to red meat consumption. PMID: 17627011 |
Ref: Sulindac and its metabolites induce carcinogen metabolizing enzymes in human colon cancer cells. PMID: 17985343 Ref: Red meat intake, doneness, polymorphisms in genes that encode carcinogen-metabolizing enzymes, and colorectal cancer risk. PMID: 18990750 |
Ref: CYP1B1, but not CYP1A1, is downregulated by promoter methylation in colorectal cancers. PMID: 19287966 |
Ref: Biochanin A induction of sulfotransferases in rats. PMID: 20391625 Ref: Metabolic bioactivation of oestradiol-17beta (E2beta) in mouse colon epithelial cells bearing ApcMin mutation. PMID: 20417221 Ref: Variant alleles of the CYP1B1 gene are associated with colorectal cancer susceptibility. PMID: 20701755 Ref: Association between exposure-relevant polymorphisms in CYP1B1, EPHX1, NQO1, GSTM1, GSTP1 and GSTT1 and risk of colorectal cancer in a Czech population. PMID: 20878130 Ref: Cigarette smoking, genetic variants in carcinogen-metabolizing enzymes, and colorectal cancer risk. PMID: 20937634 |
Ref: Genetic variation in the bioactivation pathway for polycyclic hydrocarbons and heterocyclic amines in relation to risk of colorectal neoplasia. PMID: 21081473 Ref: Single and concerted effects of benzo[a]pyrene and flavonoids on the AhR and Nrf2-pathway in the human colon carcinoma cell line Caco-2. PMID: 21256954 Ref: Association of genetic polymorphisms in ESR2, HSD17B1, ABCB1, and SHBG genes with colorectal cancer risk. PMID: 21317201 Ref: Modification of menopausal hormone therapy-associated colorectal cancer risk by polymorphisms in sex steroid signaling, metabolism and transport related genes. PMID: 21490239 |
Ref: Carcinogen metabolism genes, red meat and poultry intake, and colorectal cancer risk. PMID: 21618522 Ref: CYP1B1 Leu432Val polymorphism and colorectal cancer risk among Caucasians: a meta-analysis. PMID: 22190224 Ref: CYP1B1 Asn453Ser polymorphism and colorectal cancer risk: a meta-analysis. PMID: 22459615 Ref: Cytotoxic and potent CYP1 inhibitors from the marine algae Cymopolia barbata. PMID: 22686946 |
Ref: Expression of CYP1A1, CYP1B1 and MnSOD in a panel of human cancer cell lines. PMID: 23873331 Ref: Different susceptibility of colon cancer DLD-1 and LOVO cell lines to apoptosis induced by DMU-212, a synthetic resveratrol analogue. PMID: 24055891 Ref: Influence of dietary fat type on benzo(a)pyrene [B(a)P] biotransformation in a B(a)P-induced mouse model of colon cancer. PMID: 24231098 Ref: Expression profile of CYP1A1 and CYP1B1 enzymes in colon and bladder tumors. PMID: 24358191 |
Ref: Association between CYP1A2 and CYP1B1 polymorphisms and colorectal cancer risk: a meta-analysis. PMID: 25115775 Ref: Meat-derived carcinogens, genetic susceptibility and colorectal adenoma risk. PMID: 25231222 Ref: Interleukin-6 mediated upregulation of CYP1B1 and CYP2E1 in colorectal cancer involves DNA methylation, miR27b and STAT3. PMID: 25333344 |
Ref: Aryl Hydrocarbon Receptor Activity of Tryptophan Metabolites in Young Adult Mouse Colonocytes. PMID: 25873348 Ref: Polymorphic Variants of Cytochrome P450: Relevance to Cancer and Other Diseases. PMID: 26233904 |
Ref: Aberrant DNA Methylation: Implications in Racial Health Disparity. PMID: 27111221 |
Ref: Editor's Highlight: Microbial-Derived 1,4-Dihydroxy-2-naphthoic Acid and Related Compounds as Aryl Hydrocarbon Receptor Agonists/Antagonists: Structure-Activity Relationships and Receptor Modeling. PMID: 27837168 Ref: Short Chain Fatty Acids Enhance Aryl Hydrocarbon (Ah) Responsiveness in Mouse Colonocytes and Caco-2 Human Colon Cancer Cells. PMID: 28860561 |
Ref: Polymorphisms of xenobiotic-metabolizing genes and colorectal cancer risk in patients with lynch syndrome: A retrospective cohort study in Taiwan. PMID: 28714190 Ref: Involvement of CYP1B1 in interferon gamma-induced alterations of epithelial barrier integrity. PMID: 29232759 Ref: Alteration of benzo(a)pyrene biotransformation by resveratrol in Apc (Min/+) mouse model of colon carcinogenesis. PMID: 29931584 Ref: Expression of CYP and GST in human normal and colon tumor tissues. PMID: 30092668 |