Primary Site >> Colorectal Cancer
Gene >> CYBB
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Ref: NADPH oxidase subunit, gp91(phox) homologue, preferentially expressed in human colon epithelial cells. PMID: 10974555 |
Ref: Role of nicotinamide adenine dinucleotide phosphate oxidase 1 in oxidative burst response to Toll-like receptor 5 signaling in large intestinal epithelial cells. PMID: 14978110 |
Ref: Nox1 downstream of 12-lipoxygenase controls cell proliferation but not cell spreading of colon cancer cells. PMID: 18076063 Ref: Nox1 is over-expressed in human colon cancers and correlates with activating mutations in K-Ras. PMID: 18398843 Ref: The involvement of the tyrosine kinase c-Src in the regulation of reactive oxygen species generation mediated by NADPH oxidase-1. PMID: 18463161 |
Ref: Novel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activity. PMID: 19755710 |
Ref: Optimization and Characterization of an Inhibitor for NADPH Oxidase 1 (NOX-1) PMID: 22834042 |
Ref: Integrated Analysis Reveals hsa-miR-142 as a Representative of a Lymphocyte-Specific Gene Expression and Methylation Signature. PMID: 22570537 Ref: TLR-4 signalling accelerates colon cancer cell adhesion via NF-kappaB mediated transcriptional up-regulation of Nox-1. PMID: 23071493 |
Ref: Midazolam induces cellular apoptosis in human cancer cells and inhibits tumor growth in xenograft mice. PMID: 24008365 Ref: Selective recapitulation of conserved and nonconserved regions of putative NOXA1 protein activation domain confers isoform-specific inhibition of Nox1 oxidase and attenuation of endothelial cell migration. PMID: 24187133 |
Ref: Atmospheric pressure gas plasma-induced colorectal cancer cell death is mediated by Nox2-ASK1 apoptosis pathways and oxidative stress is mitigated by Srx-Nrf2 anti-oxidant system. PMID: 25173814 |
Ref: NOX1 to NOX2 switch deactivates AMPK and induces invasive phenotype in colon cancer cells through overexpression of MMP-7. PMID: 26116564 |
Ref: beta-eudesmol, a sesquiterpene from Teucrium ramosissimum, inhibits superoxide production, proliferation, adhesion and migration of human tumor cell. PMID: 27497729 |
Ref: Peptide screen identifies a new NADPH oxidase inhibitor: impact on cell migration and invasion. PMID: 27743884 Ref: NOX2-ROS-HIF-1alpha signaling is critical for the inhibitory effect of oleanolic acid on rectal cancer cell proliferation. PMID: 27938946 Ref: NOX2-dependent ATM kinase activation dictates pro-inflammatory macrophage phenotype and improves effectiveness to radiation therapy. PMID: 28574504 |
Ref: Identification and Characterization of a Novel NADPH Oxidase 1 (Nox1) Inhibitor That Suppresses Proliferation of Colon and Stomach Cancer Cells. PMID: 29269607 Ref: Histamine targets myeloid-derived suppressor cells and improves the anti-tumor efficacy of PD-1/PD-L1 checkpoint blockade. PMID: 30315349 |