Primary Site >> Colorectal Cancer

Gene >> CXCR5

  • 1997
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Ref: Characterization of colorectal-cancer-related cDNA clones obtained by subtractive hybridization screening.
PMID: 9292708
Ref: Prediction of lymph node metastasis in colorectal carcinoma by expressionof chemokine receptor CCR7.
PMID: 15828050
Ref: The CXCR5 chemokine receptor is expressed by carcinoma cells and promotes growth of colon carcinoma in the liver.
PMID: 17018614
Ref: C-X-C chemokine receptor type 5 gene polymorphism affects gene expression in CD4+ T cells and is associated with increased risk of colorectal cancer.
PMID: 24833093
Ref: Circulating follicular helper T cells in Crohn's disease (CD) and CD-associated colorectal cancer.
PMID: 24943684
Ref: Expression features of CXCR5 and its ligand, CXCL13 associated with poor prognosis of advanced colorectal cancer.
PMID: 25010623
Ref: CXCL13-CXCR5 axis promotes the growth and invasion of colon cancer cells via PI3K/AKT pathway.
PMID: 25476740
Ref: The Expression and Significance of CXCR5 and MMP-13 in Colorectal Cancer.
PMID: 25726157
Ref: Inflammatory regulatory T cells in the microenvironments of ulcerative colitis and colon carcinoma.
PMID: 27622054
Ref: Histidine decarboxylase (HDC)-expressing granulocytic myeloid cells induce and recruit Foxp3(+) regulatory T cells in murine colon cancer.
PMID: 28405523
Ref: CXCR5(+)CD8(+) T cells infiltrate the colorectal tumors and nearby lymph nodes, and are associated with enhanced IgG response in B cells.
PMID: 28412245
Ref: Upregulation of bacterial-specific Th1 and Th17 responses that are enriched in CXCR5(+)CD4(+) T cells in non-small cell lung cancer.
PMID: 28982050
Ref: Colorectal cancer-infiltrating T lymphocytes display a distinct chemokine receptor expression profile.
PMID: 29020986
Ref: CD8(+)CXCR5(+) T cells in tumor-draining lymph nodes are highly activated and predict better prognosis in colorectal cancer.
PMID: 29544815
Ref: Follicular helper T cells promote the effector functions of CD8(+) T cells via the provision of IL-21, which is downregulated due to PD-1/PD-L1-mediated suppression in colorectal cancer.
PMID: 30205088