Primary Site >> Stomach Cancer
Gene >> CXCR4
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Ref: CXCR4 mRNA expression in colon, esophageal and gastric cancers and hepatitis C infected liver. PMID: 10200342 |
Ref: Expression of chemokine receptors in human gastric cancer. PMID: 15867478 Ref: Overexpression of G protein-coupled receptors in cancer cells: involvement in tumor progression. PMID: 16211229 |
Ref: Role of the CXCL12/CXCR4 axis in peritoneal carcinomatosis of gastric cancer. PMID: 16489019 Ref: Gene expression patterns in gastric cancer. PMID: 16604482 |
Ref: Clinical implication of CXCL12 expression in gastric cancer. PMID: 17653799 Ref: Immunophenotype of isolated tumour cells in the blood, bone marrow and lymph nodes of patients with gastric cancer. PMID: 17715675 Ref: Chemokine receptors in cancer metastasis and cancer cell-derived chemokines in host immune response. PMID: 17894551 Ref: [Establishment of a CXCR4-expressing gastric cancer cell line in nude mice and the effect of AMD 3100 on tumor regression]. PMID: 18219852 |
Ref: Helicobacter pylori and antrum erosion-specific gene expression patterns: the discriminative role of CXCL13 and VCAM1 transcripts. PMID: 18321301 Ref: [Effect of chemokine stromal cell derived factor-1 and its receptor CXCR4 on the peritoneal carcinometastasis of gastric cancer]. PMID: 18361822 Ref: Blocking on the CXCR4/mTOR signalling pathway induces the anti-metastatic properties and autophagic cell death in peritoneal disseminated gastric cancer cells. PMID: 18375114 Ref: PGK1 a potential marker for peritoneal dissemination in gastric cancer. PMID: 18453750 Ref: Expression of CXCL12 and CXCR4 in pT3-stage gastric cancer does not correlate with peritoneal metastasis. PMID: 18949410 |
Ref: Secreted trefoil factor 2 activates the CXCR4 receptor in epithelial and lymphocytic cancer cell lines. PMID: 19064997 Ref: Chemokine receptor CXCR4 expression, function, and clinical implications in gastric cancer. PMID: 19148483 Ref: CCR7 and CXCR4 expression predicts lymph node status including micrometastasis in gastric cancer. PMID: 19513547 Ref: Expression of CXCR4 and its ligand SDF-1 in intestinal-type gastric cancer is associated with lymph node and liver metastasis. PMID: 20032431 Ref: Combination of circulating CXCR4 and Bmi-1 mRNA in plasma: A potential novel tumor marker for gastric cancer. PMID: 21475899 |
Ref: Phosphoglycerate kinase 1 a promoting enzyme for peritoneal dissemination in gastric cancer. PMID: 19688824 Ref: Integrative genomic analyses of CXCR4: transcriptional regulation of CXCR4 based on TGFbeta, Nodal, Activin signaling and POU5F1, FOXA2, FOXC2, FOXH1, SOX17, and GFI1 transcription factors. PMID: 20043076 Ref: Vascular CXCR4 expression - a novel antiangiogenic target in gastric cancer? PMID: 20386750 Ref: CXCR4, a potential predictive marker for docetaxel sensitivity in gastric cancer. PMID: 20651371 Ref: Involvement of tumor necrosis factor-alpha in the upregulation of CXCR4 expression in gastric cancer induced by Helicobacter pylori. PMID: 20699000 Ref: [Effects of oxymatrine injection combined with low-dose paclitaxel on mRNA and protein expressions of vascular endothelial growth factor and CXC chemokine receptor 4 in human gastric carcinoma SGC-7901 cells]. PMID: 21078266 Ref: [Chemokine and chemokine receptor related to cancer metastasis]. PMID: 21084802 Ref: Adipose-derived stem cells promote gastric cancer cell growth, migration and invasion through SDF-1/CXCR4 axis. PMID: 21443090 |
Ref: The EGFR ligands amphiregulin and heparin-binding egf-like growth factor promote peritoneal carcinomatosis in CXCR4-expressing gastric cancer. PMID: 21482691 Ref: CXCR4/SDF-1 axis is involved in lymph node metastasis of gastric carcinoma. PMID: 21633638 Ref: Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4. PMID: 21880153 Ref: HER2 interacts with CD44 to up-regulate CXCR4 via epigenetic silencing of microRNA-139 in gastric cancer cells. PMID: 21925125 Ref: Evaluation of the combined expression of chemokine SDF-1alpha and its receptor CXCR4 as a prognostic marker for gastric cancer. PMID: 22977531 |
Ref: The expression of CXCL12 and CXCR4 in gastric cancer and their correlation to lymph node metastasis. PMID: 21630055 Ref: Identification of cancer stem cells in vincristine preconditioned SGC7901 gastric cancer cell line. PMID: 21913215 Ref: Down-regulation of CXCL12 by DNA hypermethylation and its involvement in gastric cancer metastatic progression. PMID: 21960286 Ref: The role of CXC chemokines in the transition of chronic inflammation to esophageal and gastric cancer. PMID: 22079531 Ref: Stem cells with fused gene expression of cytosine deaminase and interferon-beta migrate to human gastric cancer cells and result in synergistic growth inhibition for potential therapeutic use. PMID: 22159640 Ref: Therapeutics target of CXCR4 and its downstream in peritoneal carcinomatosis of gastric cancer. PMID: 22202059 Ref: Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells. PMID: 22337890 Ref: First evidence that gamma-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-kappaB pathway. PMID: 22351692 Ref: The influence of transforming growth factor-alpha, cyclooxygenase-2, matrix metalloproteinase (MMP)-7, MMP-9 and CXCR4 proteins involved in epithelial-mesenchymal transition on overall survival of patients with gastric cancer. PMID: 22582975 Ref: Fluorescent magnetic nanoparticle-labeled mesenchymal stem cells for targeted imaging and hyperthermia therapy of in vivo gastric cancer. PMID: 22709686 Ref: CD8(+) T cells that produce interleukin-17 regulate myeloid-derived suppressor cells and are associated with survival time of patients with gastric cancer. PMID: 22710190 Ref: The role of the CXCR4/CXCL12 axis and its clinical implications in gastric cancer. PMID: 22806902 Ref: Hypoxia induces CXCR4 expression and biological activity in gastric cancer cells through activation of hypoxia-inducible factor-1alpha. PMID: 23023480 Ref: [Inhibitory effect of CXCR4 blockers on a CXCR4-expressing gastric cancer cell line in nude mice]. PMID: 23267887 |
Ref: Stromal cell-derived factor-1 overexpression induces gastric dysplasia through expansion of stromal myofibroblasts and epithelial progenitors. PMID: 22362916 Ref: SFRP5 inhibits gastric epithelial cell migration induced by macrophage-derived Wnt5a. PMID: 23054609 Ref: Regulation of CXCR4-mediated invasion by DARPP-32 in gastric cancer cells. PMID: 23160836 Ref: Mesenchymal stem cells utilize CXCR4-SDF-1 signaling for acute, but not chronic, trafficking to gastric mucosal inflammation. PMID: 23873382 Ref: [Ways to personalized medicine for gastric cancer]. PMID: 23907566 Ref: Upregulated expression of C-X-C chemokine receptor 4 is an independent prognostic predictor for patients with gastric cancer. PMID: 23936528 Ref: RhoE promotes metastasis in gastric cancer through a mechanism dependent on enhanced expression of CXCR4. PMID: 24312338 |
Ref: The prognosis and clinicopathology of CXCR4 in gastric cancer patients: a meta-analysis. PMID: 24464926 Ref: The chemokine receptor CXCR4 is associated with the staging of gastric cancer. PMID: 24592366 Ref: Nuclear pattern of CXCR4 expression is associated with a better overall survival in patients with gastric cancer. PMID: 24659999 Ref: Characterization of sonic hedgehog inhibition in gastric carcinoma cells. PMID: 24765141 Ref: Resistin-induced stromal cell-derived factor-1 expression through Toll-like receptor 4 and activation of p38 MAPK/ NFkappaB signaling pathway in gastric cancer cells. PMID: 24929539 Ref: Can expression of CXCL12 and CXCR4 be used to predict survival of gastric cancer patients? PMID: 25075029 Ref: Nuclear expression of chemokine receptor CXCR4 indicates poorer prognosis in gastric cancer. PMID: 25368239 Ref: The saponin DT-13 inhibits gastric cancer cell migration through down-regulation of CCR5-CCL5 axis. PMID: 25480514 |
Ref: Bone marrow derived "fibrocytes" contribute to tumor proliferation and fibrosis in gastric cancer. PMID: 24792410 Ref: Heat shock protein A4 controls cell migration and gastric ulcer healing. PMID: 25655005 Ref: Identification and Characterization of CXCR4-Positive Gastric Cancer Stem Cells. PMID: 26110809 Ref: Diffuse-type gastric cancer cells switch their driver pathways from FGFR2 signaling to SDF1/CXCR4 axis in hypoxic tumor microenvironments. PMID: 26385890 |
Ref: CXCL12/CXCR4 activation by cancer-associated fibroblasts promotes integrin beta1 clustering and invasiveness in gastric cancer. PMID: 26414794 Ref: Lifting the Mist on Gastric Stem Cells. PMID: 26748749 Ref: CXCL12/CXCR4 display an inverse mRNA expression profile in gastric carcinoma that correlates with tumor progression. PMID: 26870218 Ref: Transcription factor RUNX2 up-regulates chemokine receptor CXCR4 to promote invasive and metastatic potentials of human gastric cancer. PMID: 27007162 Ref: Target research on tumor biology characteristics of mir-155-5p regulation on gastric cancer cell. PMID: 27113301 Ref: Peripheral trafficking of bone-marrow-derived stem cells in patients with different types of gastric neoplasms. PMID: 27141380 Ref: SRF promotes gastric cancer metastasis through stromal fibroblasts in an SDF1-CXCR4-dependent manner. PMID: 27323859 Ref: SDF-1/CXCR7 axis regulates the proliferation, invasion, adhesion, and angiogenesis of gastric cancer cells. PMID: 27716367 Ref: [Expression of ALDH1, CXCR4 and E-cadherin in castric carcinoma and their roles in lymphatic metastasis]. PMID: 27777204 |
Ref: The promotion of the transformation of quiescent gastric cancer stem cells by IL-17 and the underlying mechanisms. PMID: 27524415 Ref: CXCR7 as a chemokine receptor for SDF-1 promotes gastric cancer progression via MAPK pathways. PMID: 28281844 Ref: DC - SIGNR by influencing the lncRNA HNRNPKP2 upregulates the expression of CXCR4 in gastric cancer liver metastasis. PMID: 28403883 Ref: A positive crosstalk between CXCR4 and CXCR2 promotes gastric cancer metastasis. PMID: 28481874 Ref: Regorafenib inhibited gastric cancer cells growth and invasion via CXCR4 activated Wnt pathway. PMID: 28489887 Ref: C-X-C motif chemokine receptor 4 promotes tumor angiogenesis in gastric cancer via activation of JAK2/STAT3. PMID: 28544312 Ref: Inhibition of CXCL12/CXCR4 axis as a potential targeted therapy of advanced gastric carcinoma. PMID: 28544785 Ref: CXCL12/SDF-1alpha induces migration via SRC-mediated CXCR4-EGFR cross-talk in gastric cancer cells. PMID: 28781651 Ref: B7-H3 promotes gastric cancer cell migration and invasion. PMID: 29069741 Ref: CXCR4-expressing Mist1(+) progenitors in the gastric antrum contribute to gastric cancer development. PMID: 29340033 |
Ref: A selective sphingosine-1-phosphate receptor 1 agonist SEW-2871 aggravates gastric cancer by recruiting myeloid-derived suppressor cells. PMID: 29036438 Ref: Combined Evaluation of Expression of CXCR4 and Nrf2 as Prognostic Factor for Patients with Gastric Carcinoma. PMID: 29110625 Ref: The Chemokine Receptor CXCR4 and c-MET Cooperatively Promote Epithelial-Mesenchymal Transition in Gastric Cancer Cells. PMID: 29494948 Ref: JWA suppresses the invasion of human breast carcinoma cells by downregulating the expression of CXCR4. PMID: 29658570 Ref: Circ_0056618 and CXCR4 act as competing endogenous in gastric cancer by regulating miR-206. PMID: 30129184 |