Primary Site >> Colorectal Cancer
Gene >> CXCL8
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Ref: Growth-related enzymatic control of glycogen metabolism in cultured human tumor cells. PMID: 6418376 |
Ref: Interleukin 8: cells of origin in inflammatory bowel disease. PMID: 8566866 |
Ref: Interaction between bacterial peptides, neutrophils and goblet cells: a possible mechanism for neutrophil recruitment and goblet cell depletion in colitis. PMID: 11566077 |
Ref: Peripheral blood immunological parameters for use as markers of pre-invasive to invasive colorectal cancer. PMID: 11915173 |
Ref: Association of common polymorphisms in inflammatory genes interleukin (IL)6, IL8, tumor necrosis factor alpha, NFKB1, and peroxisome proliferator-activated receptor gamma with colorectal cancer. PMID: 12839942 |
Ref: NF-kappaB, macrophage migration inhibitory factor and cyclooxygenase-inhibitions as likely mechanisms behind the acetaminophen- and NSAID-prevention of the ovarian cancer. PMID: 15254653 |
Ref: Colorectal cancer metastases affect the biochemical characteristics of the human liver beta-adrenoceptor-G-protein-adenylate cyclase system. PMID: 16300899 Ref: Inflammation-related gene polymorphisms and colorectal adenoma. PMID: 16775170 |
Ref: Chemokine expression is associated with the accumulation of tumour associated macrophages (TAMs) and progression in human colorectal cancer. PMID: 17390111 Ref: CXCL10 promotes invasion-related properties in human colorectal carcinoma cells. PMID: 17409450 Ref: Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease. PMID: 17449633 |
Ref: High prevalence of Foxp3 and IL17 in MMR-proficient colorectal carcinomas. PMID: 17965063 Ref: Interleukin promoter polymorphisms and prognosis in colorectal cancer. PMID: 18448485 Ref: Constructing disease-specific gene networks using pair-wise relevance metric: application to colon cancer identifies interleukin 8, desmin and enolase 1 as the central elements. PMID: 18691435 Ref: Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study. PMID: 18992148 Ref: Gene expression deregulation by KRAS G12D and G12V in a BRAF V600E context. PMID: 19087308 |
Ref: Expression of chemokines and chemokine receptors in human colon cancer. PMID: 19446722 Ref: Role of lipoxins and resolvins as anti-inflammatory and proresolving mediators in colon cancer. PMID: 19601807 Ref: Association of common polymorphisms in IL10, and in other genes related to inflammatory response and obesity with colorectal cancer. PMID: 19760027 Ref: RAS mutations affect tumor necrosis factor-induced apoptosis in colon carcinoma cells via ERK-modulatory negative and positive feedback circuits along with non-ERK pathway effects. PMID: 19789336 |
Ref: IL-17 promotes p38 MAPK-dependent endothelial activation enhancing neutrophil recruitment to sites of inflammation. PMID: 20228195 Ref: Expression of angiostatic platelet factor-4var/CXCL4L1 counterbalances angiogenic impulses of vascular endothelial growth factor, interleukin-8/CXCL8, and stromal cell-derived factor 1/CXCL12 in esophageal and colorectal cancer. PMID: 20334899 |
Ref: The inflammatory microenvironment in colorectal neoplasia. PMID: 21249124 Ref: The expression and prognostic impact of CXC-chemokines in stage II and III colorectal cancer epithelial and stromal tissue. PMID: 21285972 Ref: Carcinoma-derived interleukin-8 disorients dendritic cell migration without impairing T-cell stimulation. PMID: 21423807 Ref: SNAIL regulates interleukin-8 expression, stem cell-like activity, and tumorigenicity of human colorectal carcinoma cells. PMID: 21640118 Ref: Prognostic and predictive potential molecular biomarkers in colon cancer. PMID: 21696062 Ref: Case-control study for colorectal cancer genetic susceptibility in EPICOLON: previously identified variants and mucins. PMID: 21819567 Ref: Tumor-associated Macrophages (TAM) and Inflammation in Colorectal Cancer. PMID: 21909876 |
Ref: Neutrophil transintestinal epithelial migration to CXCR2 ligands is regulated by adenosine. PMID: 21857250 Ref: DNA promoter methylation status and protein expression of interleukin-8 in human colorectal adenocarcinomas. PMID: 22108905 Ref: Novel multiplex method to assess insulin, leptin and adiponectin regulation of inflammatory cytokines associated with colon cancer. PMID: 22193626 Ref: Systems biology approach to identify gene network signatures for colorectal cancer. PMID: 22629282 Ref: Identification of candidate colon cancer biomarkers by applying a random forest approach on microarray data. PMID: 22752057 Ref: IL8 and serum soluble TRAIL levels following anti-VEGF monoclonal antibody treatment in patients with metastatic colon cancer. PMID: 22783581 Ref: Erratum to "IL8 and serum soluble TRAIL levels following anti-VEGF monoclonal antibody treatment in patients with metastatic colon cancer" [Clin. Lab. 2012; 58:501-505]. PMID: 23163132 |
Ref: Interleukin genes and associations with colon and rectal cancer risk and overall survival. PMID: 22674296 Ref: Gene expression analysis of normal and colorectal cancer tissue samples from fresh frozen and matched formalin-fixed, paraffin-embedded (FFPE) specimens after manual and automated RNA isolation. PMID: 23036325 Ref: Clinical applications of gene expression in colorectal cancer. PMID: 23730510 Ref: Level of TNF-related apoptosis-inducing-ligand and CXCL8 correlated with 2-[18F]Fluoro-2-deoxy-D-glucose uptake in anti-VEGF treated colon cancers. PMID: 24145180 Ref: EFFECTS OF STANDARD AND/OR GLUTAMINE DIPEPTIDE AND/OR OMEGA-3 FATTY ASCID-SUPPLEMENTED PARENTERAL NUTRITION ON NEUTROPHIL FUNCTIONS, INTERLEUKIN-8 LEVEL AND LENGTH OF STAY--A DOUBLE BLIND,CONTROLLED, RANDOMISED STUDY. PMID: 26866103 |
Ref: CCL20 and CXCL8 synergize to promote progression and poor survival outcome in patients with colorectal cancer by collaborative induction of the epithelial-mesenchymal transition. PMID: 24657657 Ref: Differential gene expression of chemokines in KRAS and BRAF mutated colorectal cell lines: role of cytokines. PMID: 24659889 Ref: Blood eosinophil and platelet levels, proteomics patterns of trail and CXCL8 correlated with survival in bevacizumab treated metastatic colon cancers. PMID: 24660552 Ref: Association of serum and intratumoral cytokine profiles with tumor stage and neutrophil lymphocyte ratio in colorectal cancer. PMID: 24982357 Ref: Characterization of an adaptive immune response in microsatellite-instable colorectal cancer. PMID: 25101223 Ref: Variable NF-kappaB pathway responses in colon cancer cells treated with chemotherapeutic drugs. PMID: 25134433 Ref: Low molecular weight hyaluronan-pulsed human dendritic cells showed increased migration capacity and induced resistance to tumor chemoattraction. PMID: 25238610 Ref: Expression of interleukine-8 as an independent prognostic factor for sporadic colon cancer dissemination. PMID: 25408728 |
Ref: Pharmacogenetic Analysis of INT 0144 Trial: Association of Polymorphisms with Survival and Toxicity in Rectal Cancer Patients Treated with 5-FU and Radiation. PMID: 25589620 Ref: CXCL8, overexpressed in colorectal cancer, enhances the resistance of colorectal cancer cells to anoikis. PMID: 25687885 Ref: Nampt/PBEF/visfatin upregulation in colorectal tumors, mirrored in normal tissue and whole blood of colorectal cancer patients, is associated with metastasis, hypoxia, IL1beta, and anemia. PMID: 26075243 Ref: Cell Free DNA of Tumor Origin Induces a 'Metastatic' Expression Profile in HT-29 Cancer Cell Line. PMID: 26133168 Ref: Discovery of Novel CXCR2 Inhibitors Using Ligand-Based Pharmacophore Models. PMID: 26153616 Ref: Gene-expression analysis of a colorectal cancer-specific discriminatory transcript set on formalin-fixed, paraffin-embedded (FFPE) tissue samples. PMID: 26208990 Ref: Vitamin D, Inflammation, and Colorectal Cancer Progression: A Review of Mechanistic Studies and Future Directions for Epidemiological Studies. PMID: 26396142 Ref: The role of interleukin-8 (CXCL8) and CXCR2 in acquired chemoresistance of human colorectal carcinoma cells HCT116. PMID: 26519257 Ref: Microarray Analysis of Gene Expression at the Tumor Front of Colon Cancer. PMID: 26637872 |
Ref: Circulating Inflammatory Mediators as Potential Prognostic Markers of Human Colorectal Cancer. PMID: 26859579 Ref: Predictive Value of Growth Factors and Interleukins for Future Liver Remnant Volume and Colorectal Liver Metastasis Volume Growth Following Portal Vein Embolization and Autologous Stem Cell Application. PMID: 27069178 Ref: Curcumin mediates oxaliplatin-acquired resistance reversion in colorectal cancer cell lines through modulation of CXC-Chemokine/NF-kappaB signalling pathway. PMID: 27091625 Ref: Filtered selection coupled with support vector machines generate a functionally relevant prediction model for colorectal cancer. PMID: 27330311 Ref: Intricate Macrophage-Colorectal Cancer Cell Communication in Response to Radiation. PMID: 27513864 Ref: The CXCL8-CXCR1/2 pathways in cancer. PMID: 27578214 Ref: Identification of key pathways and genes in colorectal cancer using bioinformatics analysis. PMID: 27581154 Ref: Novel Biomarker Candidates for Colorectal Cancer Metastasis: A Meta-analysis of In Vitro Studies. PMID: 27688707 Ref: A module of inflammatory cytokines defines resistance of colorectal cancer to EGFR inhibitors. PMID: 27708224 |
Ref: Germline polymorphisms as biomarkers of tumor response in colorectal cancer patients treated with anti-EGFR monoclonal antibodies: a systematic review and meta-analysis. PMID: 27897268 Ref: CXCL8 induces epithelial-mesenchymal transition in colon cancer cells via the PI3K/Akt/NF-kappaB signaling pathway. PMID: 28259918 Ref: Homeobox B9 Mediates Resistance to Anti-VEGF Therapy in Colorectal Cancer Patients. PMID: 28298545 Ref: Expression of pattern recognition receptor genes and mortality in patients with colorectal adenocarcinoma. PMID: 28533893 Ref: Evasin-displaying lactic acid bacteria bind different chemokines and neutralize CXCL8 production in Caco-2 cells. PMID: 28736998 Ref: Transcriptome analysis in primary colorectal cancer tissues from patients with and without liver metastases using next-generation sequencing. PMID: 28745433 Ref: IL-32alpha-induced inflammation constitutes a link between obesity and colon cancer. PMID: 28811968 Ref: Neutrophil Extracellular Trap Production in Patients with Colorectal Cancer In Vitro. PMID: 28828191 Ref: Inhibition of PI3K/Akt/mTOR signaling in PI3KR2-overexpressing colon cancer stem cells reduces tumor growth due to apoptosis. PMID: 28881576 Ref: A transcriptome-based protein network that identifies new therapeutic targets in colorectal cancer. PMID: 28962550 |
Ref: MicroRNA-204 Inhibits the Growth and Motility of Colorectal Cancer Cells by Downregulation of CXCL8. PMID: 29402343 Ref: Tumour vasculature immaturity, oxidative damage and systemic inflammation stratify survival of colorectal cancer patients on bevacizumab treatment. PMID: 29535825 Ref: Stromal miR-20a controls paracrine CXCL8 secretion in colitis and colon cancer. PMID: 29560130 Ref: Polymorphisms in genes related to inflammation and obesity and colorectal adenoma risk. PMID: 29802748 Ref: Angiodrastic Chemokines in Colorectal Cancer: Clinicopathological Correlations. PMID: 29850390 Ref: Interleukin 8 is a biomarker of telomerase inhibition in cancer cells. PMID: 29986697 Ref: Doxorubicin resistance induces IL6 activation in the colon cancer cell line LS180. PMID: 30344742 |