Primary Site >> Colorectal Cancer
Gene >> CUL4A
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Ref: A WNT/p21 circuit directed by the C-clamp, a sequence-specific DNA binding domain in TCFs. PMID: 22778133 |
Ref: CUL4A induces epithelial-mesenchymal transition and promotes cancer metastasis by regulating ZEB1 expression. PMID: 24305877 |
Ref: Jak-STAT3 pathway triggers DICER1 for proteasomal degradation by ubiquitin ligase complex of CUL4A(DCAF1) to promote colon cancer development. PMID: 26965998 Ref: DCAF4L2 promotes colorectal cancer invasion and metastasis via mediating degradation of NFkappab negative regulator PPM1B. PMID: 27158335 Ref: Aberrant Expression of CUL4A Is Associated with IL-6/ STAT3 Activation in Colorectal Cancer Progression. PMID: 27418574 |
Ref: Loss of CUL4A expression is underlying cisplatin hypersensitivity in colorectal carcinoma cells with acquired trabectedin resistance. PMID: 28095394 Ref: CUL4A promotes proliferation and metastasis of colorectal cancer cells by regulating H3K4 trimethylation in epithelial-mesenchymal transition. PMID: 28223829 |
Ref: A Novel lncRNA, LINC00460, Affects Cell Proliferation and Apoptosis by Regulating KLF2 and CUL4A Expression in Colorectal Cancer. PMID: 30092404 |