Primary Site >> Colorectal Cancer
Gene >> CTTN
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Ref: Dominant expression of 85-kDa form of cortactin in colorectal cancer. PMID: 16261345 Ref: Alternative splicing and differential gene expression in colon cancer detected by a whole genome exon array. PMID: 17192196 |
Ref: ROCK-II mediates colon cancer invasion via regulation of MMP-2 and MMP-13 at the site of invadopodia as revealed by multiphoton imaging. PMID: 17876296 |
Ref: Odin (ANKS1A) is a Src family kinase target in colorectal cancer cells. PMID: 18844995 |
Ref: Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion. PMID: 19138410 Ref: Localization of cortactin is associated with colorectal cancer development. PMID: 19885549 |
Ref: Expression of cortactin correlates with a poor prognosis in patients with stages II-III colorectal adenocarcinoma. PMID: 20532661 |
Ref: [A pivotal role of cortactin, a CTTN encoding protein, in endocytosis of human colon cancer]. PMID: 21418910 Ref: The candidate tumor suppressor SASH1 interacts with the actin cytoskeleton and stimulates cell-matrix adhesion. PMID: 21820526 Ref: Plectin regulates invasiveness of SW480 colon carcinoma cells and is targeted to podosome-like adhesions in an isoform-specific manner. PMID: 21821021 Ref: [Interference of invasion and metastasis of colorectal cancer cells by EMS1-siRNA encoded by a recombinant lentiviral vector]. PMID: 22116727 |
Ref: Association of CTTN polymorphisms with the risk of colorectal cancer. PMID: 22403749 Ref: Expression of cortactin and focal adhesion kinase in colorectal adenocarcinoma: correlation with clinicopathologic parameters and their prognostic implication. PMID: 23136572 |
Ref: Expression of DIAPH1 is up-regulated in colorectal cancer and its down-regulation strongly reduces the metastatic capacity of colon carcinoma cells. PMID: 24105619 Ref: PTP-PEST targets a novel tyrosine site in p120 catenin to control epithelial cell motility and Rho GTPase activity. PMID: 24284071 Ref: pTyr421 cortactin is overexpressed in colon cancer and is dephosphorylated by curcumin: involvement of non-receptor type 1 protein tyrosine phosphatase (PTPN1). PMID: 24465712 Ref: Radiation sensitization of tumor cells induced by shear stress: the roles of integrins and FAK. PMID: 24946134 |
Ref: Role of the focal adhesion protein TRIM15 in colon cancer development. PMID: 25450970 Ref: Chansu inhibits the expression of cortactin in colon cancer cell lines in vitro and in vivo. PMID: 26134506 Ref: Cortactin promotes colon cancer progression by regulating ERK pathway. PMID: 26151562 |
Ref: miR-542-3p inhibits the growth and invasion of colorectal cancer cells through targeted regulation of cortactin. PMID: 26952924 Ref: Cortactin promotes cell migration and invasion through upregulation of the dedicator of cytokinesis 1 expression in human colorectal cancer. PMID: 27633051 Ref: Asporin enhances colorectal cancer metastasis through activating the EGFR/src/cortactin signaling pathway. PMID: 27705916 |
Ref: Cortactin promotes colorectal cancer cell proliferation by activating the EGFR-MAPK pathway. PMID: 27903975 Ref: Role of Akt2 in regulation of metastasis suppressor 1 expression and colorectal cancer metastasis. PMID: 28068324 Ref: High expression of PTBP1 promote invasion of colorectal cancer by alternative splicing of cortactin. PMID: 28404950 Ref: Identification of differentially expressed genes and their upstream regulators in colorectal cancer. PMID: 28409560 |
Ref: Cortactin recruits FMNL2 to promote actin polymerization and endosome motility in invadopodia formation. PMID: 29374558 |