Primary Site >> Pancreatic Cancer
Gene >> CTNNB1
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Beta- and gamma-catenin mutations, but not E-cadherin inactivation, underlie T-cell factor/lymphoid enhancer factor transcriptional deregulation in gastric and pancreatic cancer. PMID: 10392898 Ref: Characterization of the E-cadherin-catenin complexes in pancreatic carcinoma cell lines. PMID: 10398158 Ref: Hollow-spheres: a new model for analyses of differentiation of pancreatic duct epithelial cells. PMID: 10415853 Ref: Analysis of beta-catenin gene mutations in pancreatic tumors. PMID: 10545724 |
Ref: Reduced membranous and ectopic cytoplasmic expression of beta -catenin correlate with cyclin D1 overexpression and poor prognosis in pancreatic cancer. PMID: 11307154 Ref: FGF-1 and FGF-2 modulate the E-cadherin/catenin system in pancreatic adenocarcinoma cell lines. PMID: 11401320 Ref: Distinctive molecular genetic alterations in sporadic and familial adenomatous polyposis-associated pancreatoblastomas : frequent alterations in the APC/beta-catenin pathway and chromosome 11p. PMID: 11696422 Ref: Expression patterns of alpha-, beta- and gamma-catenin in pancreatic cancer: correlation with E-cadherin expression, pathological features and prognosis. PMID: 11911306 |
Ref: Familial adenomatous polyposis associated with multiple endocrine neoplasia type 1-related tumors and thyroid carcinoma: a case report with clinicopathologic and molecular analyses. PMID: 11756777 Ref: Genetic and immunohistochemical analysis of pancreatic acinar cell carcinoma: frequent allelic loss on chromosome 11p and alterations in the APC/beta-catenin pathway. PMID: 11891193 Ref: Solid-pseudopapillary tumors of the pancreas are genetically distinct from pancreatic ductal adenocarcinomas and almost always harbor beta-catenin mutations. PMID: 11943721 Ref: Molecular cloning and characterization of WRCH2 on human chromosome 15q15. PMID: 11956592 Ref: Molecular cloning and characterization of Strabismus 2 (STB2). PMID: 11956595 Ref: Expression and regulation of WNT8A and WNT8B mRNAs in human tumor cell lines: up-regulation of WNT8B mRNA by beta-estradiol in MCF-7 cells, and down-regulation of WNT8A and WNT8B mRNAs by retinoic acid in NT2 cells. PMID: 11956596 Ref: Thiazolidinedione, a peroxisome proliferator-activated receptor-gamma ligand, modulates the E-cadherin/beta-catenin system in a human pancreatic cancer cell line, BxPC-3. PMID: 12063547 Ref: Carcinogen-induced pancreatic lesions in the mouse: effect of Smad4 and Apc genotypes. PMID: 12096346 Ref: Expression and regulation of WNT5A and WNT5B in human cancer: up-regulation of WNT5A by TNFalpha in MKN45 cells and up-regulation of WNT5B by beta-estradiol in MCF-7 cells. PMID: 12165812 Ref: Restoration of E-cadherin/beta-catenin expression in pancreatic cancer cells inhibits growth by induction of apoptosis. PMID: 12219004 Ref: Expression and regulation of WNT10B in human cancer: up-regulation of WNT10B in MCF-7 cells by beta-estradiol and down-regulation of WNT10B in NT2 cells by retinoic acid. PMID: 12239602 Ref: Expression of WNT7A in human normal tissues and cancer, and regulation of WNT7A and WNT7B in human cancer. PMID: 12239632 Ref: Gastrin mediated cholecystokinin-2 receptor activation induces loss of cell adhesion and scattering in epithelial MDCK cells. PMID: 12400008 Ref: Analysis of the beta-catenin/T cell factor signaling pathway in 36 gastrointestinal and liver cancer cells. PMID: 12460462 |
Ref: Relationship between expression of E-cadherin-catenin complex and clinicopathologic characteristics of pancreatic cancer. PMID: 12532469 Ref: Dysregulation of beta-catenin expression correlates with tumor differentiation in pancreatic duct adenocarcinoma. PMID: 12679314 Ref: Advanced pancreatic ductal cancer: fibrotic focus and beta-catenin expression correlate with outcome. PMID: 12717263 Ref: Nuclear association of the cytoplasmic tail of MUC1 and beta-catenin. PMID: 12832415 Ref: [Relationship between the expression of beta-cat, cyclin D1 and c-myc and the occurance and biological behavior of pancreatic cancer]. PMID: 12882690 Ref: Pancreatic beta-cell-specific ablation of the multiple endocrine neoplasia type 1 (MEN1) gene causes full penetrance of insulinoma development in mice. PMID: 12941803 Ref: Identification and characterization of human BCL9L gene and mouse Bcl9l gene in silico. PMID: 12964048 Ref: Multicomponent analysis of the pancreatic adenocarcinoma progression model using a pancreatic intraepithelial neoplasia tissue microarray. PMID: 13679454 Ref: alpha-, beta- and chi-catenin expression in human pancreatic cancer. PMID: 14981965 |
Ref: Microcystic tubulopapillary carcinoma of the pancreas: a new tumor entity? PMID: 15014986 Ref: HPAF-II, a cell culture model to study pancreatic epithelial cell structure and function. PMID: 15367897 |
Ref: DRO1, a gene down-regulated by oncogenes, mediates growth inhibition in colon and pancreatic cancer cells. PMID: 15563452 Ref: GSK3 and PKB/Akt are associated with integrin-mediated regulation of PTHrP, IL-6 and IL-8 expression in FG pancreatic cancer cells. PMID: 15609321 Ref: [Acinar cell carcinomas and pancreatoblastomas: related but not the same]. PMID: 15614488 Ref: Immunohistochemistry as a tool in the differential diagnosis of ovarian tumors: an update. PMID: 15626916 Ref: Expression of novel markers of pancreatic ductal adenocarcinoma in pancreatic nonductal neoplasms: additional evidence of different genetic pathways. PMID: 15696124 Ref: Analysis of E-, N-cadherin, alpha-, beta-, and gamma-catenin expression in human pancreatic carcinoma cell lines. PMID: 15714139 Ref: Clinically aggressive solid pseudopapillary tumors of the pancreas: a report of two cases with components of undifferentiated carcinoma and a comparative clinicopathologic analysis of 34 conventional cases. PMID: 15767807 Ref: Beta-catenin up-regulates the expression of cyclinD1, c-myc and MMP-7 in human pancreatic cancer: relationships with carcinogenesis and metastasis. PMID: 15810077 Ref: mda-7/IL24 kills pancreatic cancer cells by inhibition of the Wnt/PI3K signaling pathways: identification of IL-20 receptor-mediated bystander activity against pancreatic cancer. PMID: 15851011 Ref: Different capabilities of morphological pattern formation and its association with the expression of differentiation markers in a xenograft model of human pancreatic cancer cell lines. PMID: 15980667 Ref: Molecular prognostic markers in pancreatic cancer: a systematic review. PMID: 16146690 Ref: TGFbeta-induced downregulation of E-cadherin-based cell-cell adhesion depends on PI3-kinase and PTEN. PMID: 16219695 Ref: Type I collagen and divalent cation shifts disrupt cell-cell adhesion, increase migration, and decrease PTHrP, IL-6, and IL-8 expression in pancreatic cancer cells. PMID: 16720909 |
Ref: The Wnt pathway is active in a small subset of pancreas cancer cell lines. PMID: 16137866 Ref: Vascular endothelial growth factor receptor-1 activation mediates epithelial to mesenchymal transition in human pancreatic carcinoma cells. PMID: 16397214 Ref: Adenomatous polyposis coli-deficient zebrafish are susceptible to digestive tract neoplasia. PMID: 16439994 Ref: FGF signaling inhibitor, SPRY4, is evolutionarily conserved target of WNT signaling pathway in progenitor cells. PMID: 16465403 Ref: Collagen type I induces disruption of E-cadherin-mediated cell-cell contacts and promotes proliferation of pancreatic carcinoma cells. PMID: 16651417 Ref: Accumulation of beta-catenin protein, mutations in exon-3 of the beta-catenin gene and a loss of heterozygosity of 5q22 in solid pseudopapillary tumor of the pancreas. PMID: 16967453 Ref: Non-cystic solid-pseudopapillary tumor of the pancreas showing nuclear accumulation and activating gene mutation of beta-catenin. PMID: 17040296 |
Ref: NRAGE suppresses metastasis of melanoma and pancreatic cancer in vitro and in vivo. PMID: 17140727 Ref: Smad4 is essential for down-regulation of E-cadherin induced by TGF-beta in pancreatic cancer cell line PANC-1. PMID: 17301079 Ref: Tyrosine kinase receptor RON in human pancreatic cancer: expression, function, and validation as a target. PMID: 17311308 Ref: Beta-catenin is a promising key factor in the SDF-1/CXCR4 axis on metastasis of pancreatic cancer. PMID: 17379424 Ref: Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells. PMID: 17417771 Ref: Nuclear expression of E-cadherin in solid pseudopapillary tumors of the pancreas. PMID: 17495358 Ref: Glycogen synthase kinase-3 beta; a new target in pancreatic cancer? PMID: 17504118 Ref: Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas. PMID: 17596282 Ref: Solid pseudopapillary neoplasms of the pancreas show an interruption of the Wnt-signaling pathway and express gene products of 11q. PMID: 17632456 Ref: Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors. PMID: 17675336 Ref: Development and characterization of gemcitabine-resistant pancreatic tumor cells. PMID: 17909916 |
Ref: Cystic neoplasia of the pancreas: pathology and biology. PMID: 17957438 Ref: E-cadherin/catenin complex status in solid pseudopapillary tumor of the pancreas. PMID: 18162763 Ref: Absence of E-cadherin expression distinguishes noncohesive from cohesive pancreatic cancer. PMID: 18223216 Ref: Loss of membrane localization and aberrant nuclear E-cadherin expression correlates with invasion in pancreatic endocrine tumors. PMID: 18300809 Ref: Functional blockade of Smad4 leads to a decrease in beta-catenin levels and signaling activity in human pancreatic carcinoma cells. PMID: 18310088 Ref: Up-regulation of MSX2 enhances the malignant phenotype and is associated with twist 1 expression in human pancreatic cancer cells. PMID: 18349132 Ref: Expression of calcyclin-binding protein/Siah-1 interacting protein in normal and malignant human tissues: an immunohistochemical survey. PMID: 18443365 Ref: Human tumor nanoparticles induce apoptosis of pancreatic cancer cells. PMID: 18511551 Ref: Inhibition of STAT3 Tyr705 phosphorylation by Smad4 suppresses transforming growth factor beta-mediated invasion and metastasis in pancreatic cancer cells. PMID: 18519681 Ref: Nuclear E-cadherin immunoexpression: from biology to potential applications in diagnostic pathology. PMID: 18580099 Ref: Revision 2: an immunohistochemical approach and evaluation of solid pseudopapillary tumour of the pancreas. PMID: 18708424 Ref: Stabilization of beta-catenin induces pancreas tumor formation. PMID: 18725219 Ref: Expression and clinical significance of CacyBP/SIP in pancreatic cancer. PMID: 18765951 Ref: Recent progress on normal and malignant pancreatic stem/progenitor cell research: therapeutic implications for the treatment of type 1 or 2 diabetes mellitus and aggressive pancreatic cancer. PMID: 18791122 Ref: Redox mechanisms switch on hypoxia-dependent epithelial-mesenchymal transition in cancer cells. PMID: 18791199 Ref: Cancer stem cells: how can we target them? PMID: 19075661 |
Ref: Expression pattern of claudins 5 and 7 distinguishes solid-pseudopapillary from pancreatoblastoma, acinar cell and endocrine tumors of the pancreas. PMID: 19194274 Ref: Expression of Wnt target genes in solid pseudopapillary tumor of the pancreas: a pilot study. PMID: 19248223 Ref: Oncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and beta-catenin stabilization. PMID: 19249679 Ref: Interaction between HSP60 and beta-catenin promotes metastasis. PMID: 19369584 Ref: Potentiation of the effect of gemcitabine by emodin in pancreatic cancer is associated with survivin inhibition. PMID: 19428321 Ref: Intraductal tubulopapillary neoplasms of the pancreas distinct from pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms. PMID: 19440145 Ref: Type I collagen inhibits differentiation and promotes a stem cell-like phenotype in human colorectal carcinoma cells. PMID: 19568234 Ref: Organotypic culture model of pancreatic cancer demonstrates that stromal cells modulate E-cadherin, beta-catenin, and Ezrin expression in tumor cells. PMID: 19608876 Ref: Fluorescence in situ hybridization to visualize genetic abnormalities in interphase cells of acinar cell carcinoma, ductal adenocarcinoma, and islet cell carcinoma of the pancreas. PMID: 19720778 Ref: Rac1 activation inhibits E-cadherin-mediated adherens junctions via binding to IQGAP1 in pancreatic carcinoma cells. PMID: 19737400 Ref: Cloning of the human GLI2 Promoter: transcriptional activation by transforming growth factor-beta via SMAD3/beta-catenin cooperation. PMID: 19797115 Ref: Nicotine promotes tumor growth and metastasis in mouse models of lung cancer. PMID: 19841737 Ref: Microadenocarcinoma of the pancreas. PMID: 19916245 Ref: [Clinical pathological analysis in 14 cases of pancreatic solid-pseudopapillary tumors]. PMID: 20019775 Ref: Immunohistochemical analyses of E-cadherin, beta-catenin, CD44s, and CD44v6 expressions, and Ki-67 labeling index in intraductal papillary mucinous neoplasms of the pancreas and associated invasive carcinomas. PMID: 20033368 Ref: Clear-cell variant of solid-pseudopapillary neoplasm of the pancreas: a case report and review of the literature. PMID: 20514858 |
Ref: Moesin-dependent cytoskeleton remodelling is associated with an anaplastic phenotype of pancreatic cancer. PMID: 19432821 Ref: Lef-1 isoforms regulate different target genes and reduce cellular adhesion. PMID: 19653274 Ref: Solid-pseudopapillary neoplasm of the pancreas with massive central calcification in an old man. PMID: 19674849 Ref: Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice. PMID: 20071774 Ref: Pathological differential diagnosis of solid-pseudopapillary neoplasm and endocrine tumors of the pancreas. PMID: 20180245 Ref: Divalent cations modulate alpha2beta1 integrin-mediated malignancy in a novel 3-dimensional in vitro model of pancreatic cancer. PMID: 20182393 Ref: Masitinib combined with standard gemcitabine chemotherapy: in vitro and in vivo studies in human pancreatic tumour cell lines and ectopic mouse model. PMID: 20209107 Ref: Sporadic, nontrauma-related, desmoid tumor of the pancreas: a rare disease-case report and literature review. PMID: 20300597 Ref: [Study on clinicopathologic features and metastasizing potential of solid pseudopapillary tumor of pancreas]. PMID: 20388395 Ref: Human Arm protein lost in epithelial cancers, on chromosome X 1 (ALEX1) gene is transcriptionally regulated by CREB and Wnt/beta-catenin signaling. PMID: 20398052 Ref: GSK3beta and beta-catenin modulate radiation cytotoxicity in pancreatic cancer. PMID: 20454507 Ref: Wnt inhibitor Dickkopf-1 as a target for passive cancer immunotherapy. PMID: 20551066 Ref: DCB-3503, a tylophorine analog, inhibits protein synthesis through a novel mechanism. PMID: 20657652 Ref: Small solid pseudopapillary tumor of the pancreas in a 32-year-old man: report of a case. PMID: 20676863 Ref: The reactive tumor microenvironment: MUC1 signaling directly reprograms transcription of CTGF. PMID: 20697347 Ref: CXCL12-CXCR4 signalling axis confers gemcitabine resistance to pancreatic cancer cells: a novel target for therapy. PMID: 21045835 Ref: Solid pseudopapillary tumor of the pancreas (SPPT). Still an unsolved enigma. PMID: 21198316 Ref: Pre-operative diagnosis of synchronous solid-pseudopapillary neoplasms of the pancreas. PMID: 26190487 |
Ref: GLI1 facilitates the migration and invasion of pancreatic cancer cells through MUC5AC-mediated attenuation of E-cadherin. PMID: 20972463 Ref: Sulforaphane synergizes with quercetin to inhibit self-renewal capacity of pancreatic cancer stem cells. PMID: 21196331 Ref: Pancreatic adenocarcinoma up-regulated factor (PAUF) enhances the expression of beta-catenin, leading to a rapid proliferation of pancreatic cells. PMID: 21196815 Ref: CacyBP/SIP protein promotes proliferation and G1/S transition of human pancreatic cancer cells. PMID: 21268134 Ref: Transient gene silencing of galectin-3 suppresses pancreatic cancer cell migration and invasion through degradation of beta-catenin. PMID: 21448903 Ref: Expression of KL-6/MUC1 in pancreatic ductal carcinoma and its potential relationship with beta-catenin in tumor progression. PMID: 21466814 Ref: Analysis of LKB1 mutations and other molecular alterations in pancreatic acinar cell carcinoma. PMID: 21572398 Ref: Expression of KL-6/MUC1 in pancreatic cancer tissues and its potential involvement in tumor metastasis. PMID: 21617869 Ref: Retinoic acid-induced pancreatic stellate cell quiescence reduces paracrine Wnt-beta-catenin signaling to slow tumor progression. PMID: 21704588 Ref: Ultraviolet enhances the sensitivity of pancreatic cancer cells to gemcitabine by activation of 5' AMP-activated protein kinase. PMID: 21945432 Ref: Somatic mutations in PIK3CA and activation of AKT in intraductal tubulopapillary neoplasms of the pancreas. PMID: 21945955 Ref: Extrapancreatic solid pseudopapillary neoplasm: report of a case of primary ovarian origin and review of the literature. PMID: 21979589 Ref: Dickkopf3 overexpression inhibits pancreatic cancer cell growth in vitro. PMID: 21987623 Ref: Caveolin-1 promotes pancreatic cancer cell differentiation and restores membranous E-cadherin via suppression of the epithelial-mesenchymal transition. PMID: 22041584 Ref: Omega-3-polyunsaturated fatty acids suppress pancreatic cancer cell growth in vitro and in vivo via downregulation of Wnt/Beta-catenin signaling. PMID: 22213040 Ref: [Regulatory mechanisms of Hedgehog signaling pathway for epithelial-mesenchymal transition in pancreatic cancer cells]. PMID: 22340649 |
Ref: A case of clear cell variant of solid-pseudopapillary tumor of the pancreas in an adult male patient. PMID: 21396870 Ref: Inhibition of mesothelin as a novel strategy for targeting cancer cells. PMID: 22485139 Ref: [Clinicopathologic features, diagnosis and treatment with solid-pseudopapillary tumor of the pancreas: a report of 33 cases]. PMID: 22490282 Ref: Adamantyl Retinoid-Related Molecules Induce Apoptosis in Pancreatic Cancer Cells by Inhibiting IGF-1R and Wnt/beta-Catenin Pathways. PMID: 22570653 Ref: The detection of EBP50 expression using quantum dot immunohistochemistry in pancreatic cancer tissue and down-regulated EBP50 effect on PC-2 cells. PMID: 22622406 Ref: SIRT1 inhibits proliferation of pancreatic cancer cells expressing pancreatic adenocarcinoma up-regulated factor (PAUF), a novel oncogene, by suppression of beta-catenin. PMID: 22640743 Ref: Pancreatic cancer cells retain the epithelial-related phenotype and modify mitotic spindle microtubules after the administration of ukrain in vitro. PMID: 22700003 Ref: Hepatoid carcinoma of the pancreas penetrating into the gastric cavity: a case report and literature review. PMID: 22726068 Ref: Glycogen synthase kinase-3 inhibition sensitizes pancreatic cancer cells to TRAIL-induced apoptosis. PMID: 22829912 Ref: Molecular markers associated with outcome and metastasis in human pancreatic cancer. PMID: 22925330 Ref: Targeting a novel onco-glycoprotein antigen at tumoral pancreatic cell surface by mAb16D10 induces cell death. PMID: 22956586 Ref: Pancreatic cancer cells surviving gemcitabine treatment express markers of stem cell differentiation and epithelial-mesenchymal transition. PMID: 23026911 Ref: Epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma and pancreatic tumor cell lines: the role of neutrophils and neutrophil-derived elastase. PMID: 23227088 |
Ref: Three female familial cases of solid pseudopapillary tumors with a protease serine 1 gene mutation. PMID: 22722260 Ref: Deguelin suppresses pancreatic tumor growth and metastasis by inhibiting epithelial-to-mesenchymal transition in an orthotopic model. PMID: 22986522 Ref: MUC1 enhances hypoxia-driven angiogenesis through the regulation of multiple proangiogenic factors. PMID: 23108411 Ref: Molecular characteristics of a pancreatic adenocarcinoma associated with Shwachman-Diamond syndrome. PMID: 23303473 Ref: Sirtuin-1 regulates acinar-to-ductal metaplasia and supports cancer cell viability in pancreatic cancer. PMID: 23370328 Ref: Mechanism of action of salinomycin on growth and migration in pancreatic cancer cell lines. PMID: 23395573 Ref: Yes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinoma. PMID: 23419361 Ref: Spontaneous rupture of an advanced pancreatoblastoma: aberrant RASSF1A methylation and CTNNB1 mutation as molecular genetic markers. PMID: 23583162 Ref: The influence of matrix properties on growth and morphogenesis of human pancreatic ductal epithelial cells in 3D. PMID: 23602364 Ref: Isolated desmoid tumor of pancreatic tail with cyst formation diagnosed by beta-catenin immunostaining: a rare case report with review of literature. PMID: 23669485 Ref: In vitro treatment of carcinoma cell lines with pancreatic (pro)enzymes suppresses the EMT programme and promotes cell differentiation. PMID: 23677639 Ref: Novel curcumin-loaded magnetic nanoparticles for pancreatic cancer treatment. PMID: 23704793 Ref: PanIN-specific regulation of Wnt signaling by HIF2alpha during early pancreatic tumorigenesis. PMID: 23749643 Ref: Central role of beta-catenin in anticancer effects of cardiac hormones. PMID: 23749889 Ref: miR-210 regulates the interaction between pancreatic cancer cells and stellate cells. PMID: 23831622 Ref: Primary cilia are lost in preinvasive and invasive prostate cancer. PMID: 23844214 Ref: Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma. PMID: 23847203 Ref: The biological features of PanIN initiated from oncogenic Kras mutation in genetically engineered mouse models. PMID: 23887057 Ref: Aberrant expression of CXCR4 and beta-catenin in pancreatic cancer. PMID: 24023356 Ref: Large solid-pseudopapillary neoplasm of the pancreas with aberrant protein expression and mutation of beta-catenin: a case report and literature review of the distribution of beta-catenin mutation. PMID: 24042511 Ref: Down-regulation of PLCgamma2-beta-catenin pathway promotes activation and expansion of myeloid-derived suppressor cells in cancer. PMID: 24127488 Ref: Two rare cases of a solid pseudopapillary neoplasm of the pancreas. PMID: 24137427 Ref: Upregulation of Wnt5a promotes epithelial-to-mesenchymal transition and metastasis of pancreatic cancer cells. PMID: 24156409 Ref: Effects of metformin on CD133+ colorectal cancer cells in diabetic patients. PMID: 24278407 |
Ref: The tumor suppressor LKB1 antagonizes WNT signaling pathway through modulating GSK3beta activity in cell growth of esophageal carcinoma. PMID: 24022664 Ref: Activated wnt signaling in stroma contributes to development of pancreatic mucinous cystic neoplasms. PMID: 24067880 Ref: Characterization of gene expression and activated signaling pathways in solid-pseudopapillary neoplasm of pancreas. PMID: 24072181 Ref: Reverse-phase protein array analysis to identify biomarker proteins in human pancreatic cancer. PMID: 24248418 Ref: Pleomorphic solid pseudopapillary neoplasm of the pancreas: degenerative change rather than high-grade malignant potential. PMID: 24321526 Ref: MUC4-induced nuclear translocation of beta-catenin: a novel mechanism for growth, metastasis and angiogenesis in pancreatic cancer. PMID: 24374017 Ref: Coupling G2/M arrest to the Wnt/beta-catenin pathway restrains pancreatic adenocarcinoma. PMID: 24402132 Ref: Case report: Intraductal tubulopapillary neoplasm of the pancreas with unique clear cell phenotype. PMID: 24443801 Ref: Antitumor efficacy of alpha-solanine against pancreatic cancer in vitro and in vivo. PMID: 24505326 Ref: miR-203 inhibits tumor cell migration and invasion via caveolin-1 in pancreatic cancer cells. PMID: 24520289 Ref: Notch pathway activation is associated with pancreatic cancer treatment failure. PMID: 24555978 Ref: Solid pseudopapillary tumor: a rare neoplasm of the pancreas. PMID: 24759340 Ref: Solid pseudopapillary tumor of the pancreas in children: 15-year experience at a single institution with assays using an immunohistochemical panel. PMID: 24761421 Ref: PP2A inhibitors suppress migration and growth of PANC-1 pancreatic cancer cells through inhibition on the Wnt/beta-catenin pathway by phosphorylation and degradation of beta-catenin. PMID: 24926961 Ref: Solid-pseudopapillary neoplasm of the pancreas: cytomorphologic findings and literature review. PMID: 24969629 Ref: MUC1 regulates cyclin D1 gene expression through p120 catenin and beta-catenin. PMID: 24979278 Ref: Clinicopathological characteristics of anaplastic carcinoma of the pancreas with rhabdoid features. PMID: 25031015 Ref: Adiponectin promotes pancreatic cancer progression by inhibiting apoptosis via the activation of AMPK/Sirt1/PGC-1alpha signaling. PMID: 25051362 Ref: 5-Azacytidine suppresses the proliferation of pancreatic cancer cells by inhibiting the Wnt/beta-catenin signaling pathway. PMID: 25061731 Ref: The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth. PMID: 25082960 Ref: Implications of PPPDE1 expression in the distribution of plakoglobin and beta-catenin in pancreatic ductal adenocarcinoma. PMID: 25120694 Ref: Accumulation of extracellular hyaluronan by hyaluronan synthase 3 promotes tumor growth and modulates the pancreatic cancer microenvironment. PMID: 25147816 Ref: Report of a case of acinar cell carcinoma with its differential diagnosis on endoscopic ultrasound-guided fine-needle aspiration cytology. PMID: 25210238 Ref: Risk factors associated with recurrence in patients with solid pseudopapillary tumors of the pancreas. PMID: 25435571 Ref: Pathology and genetics of pancreatic neoplasms with acinar differentiation. PMID: 25441307 Ref: Diagnosis and molecular aspects of solid-pseudopapillary neoplasms of the pancreas. PMID: 25524568 |
Ref: CTNNB1 mutational analysis of solid-pseudopapillary neoplasms of the pancreas using endoscopic ultrasound-guided fine-needle aspiration and next-generation deep sequencing. PMID: 24700283 Ref: Neurotensin, a novel target of Wnt/beta-catenin pathway, promotes growth of neuroendocrine tumor cells. PMID: 25098665 Ref: Pancreatic undifferentiated rhabdoid carcinoma: KRAS alterations and SMARCB1 expression status define two subtypes. PMID: 25103069 Ref: Glaucarubinone inhibits colorectal cancer growth by suppression of hypoxia-inducible factor 1alpha and beta-catenin via a p-21 activated kinase 1-dependent pathway. PMID: 25409929 Ref: MiR-23a/-24-induced gene silencing results in mesothelial cell integration of pancreatic cancer. PMID: 25422915 Ref: Stromal SLIT2 impacts on pancreatic cancer-associated neural remodeling. PMID: 25590802 Ref: Does beta-Catenin Cross-Regulate NFkappaB Signalling in Pancreatic Cancer and Chronic Pancreatitis? PMID: 25765944 Ref: S100 calcium-binding protein A6 promotes epithelial-mesenchymal transition through beta-catenin in pancreatic cancer cell line. PMID: 25799022 Ref: Solid serous cystadenoma of the pancreas: a case report of 2 patients revealing vimentin, beta-catenin, alpha-1 antitrypsin, and alpha-1 antichymotrypsin as new immunohistochemistry staining markers. PMID: 25816032 Ref: Solid pseudopapillary tumor of the pancreas in a patient with cervical cancer: relation of E-cadherin/beta-catenin adhesion complex in their carcinogenesis. PMID: 25848087 Ref: Slug-dependent upregulation of L1CAM is responsible for the increased invasion potential of pancreatic cancer cells following long-term 5-FU treatment. PMID: 25860483 Ref: Inhibition of beta-catenin signaling suppresses pancreatic tumor growth by disrupting nuclear beta-catenin/TCF-1 complex: critical role of STAT-3. PMID: 25869100 Ref: Pure alpha-fetoprotein-producing neuroendocrine carcinoma of the pancreas: a case report. PMID: 25886790 Ref: Desmoid tumor of the pancreas: a case report. PMID: 25943401 Ref: MicroRNA-33a-mediated downregulation of Pim-3 kinase expression renders human pancreatic cancer cells sensitivity to gemcitabine. PMID: 25971209 Ref: Expression of E-cadherin repressors SNAIL, ZEB1 and ZEB2 by tumour and stromal cells influences tumour-budding phenotype and suggests heterogeneity of stromal cells in pancreatic cancer. PMID: 25989272 Ref: CCR9-mediated signaling through beta-catenin and identification of a novel CCR9 antagonist. PMID: 26003048 Ref: Effect of S100A6 over-expression on beta-catenin in endometriosis. PMID: 26044826 Ref: Silencing of LRRFIP1 reverses the epithelial-mesenchymal transition via inhibition of the Wnt/beta-catenin signaling pathway. PMID: 26047573 Ref: Ape1 regulates WNT/beta-catenin signaling through its redox functional domain in pancreatic cancer cells. PMID: 26081414 Ref: miR-33a suppresses the nuclear translocation of beta-catenin to enhance gemcitabine sensitivity in human pancreatic cancer cells. PMID: 26113407 Ref: Effect of Matrine on HPAC cell migration by down-regulating the expression of MT1-MMP via Wnt signaling. PMID: 26113801 Ref: Cantharidin represses invasion of pancreatic cancer cells through accelerated degradation of MMP2 mRNA. PMID: 26135631 Ref: Distinct Protein Expression Profiles of Solid-Pseudopapillary Neoplasms of the Pancreas. PMID: 26148796 Ref: [Significance of P504s in distinction between solid pseudopapillary tumor of pancreas and pancreatic neuroendocrine tumors]. PMID: 26178213 Ref: Altering cancer transcriptomes using epigenomic inhibitors. PMID: 26191083 Ref: Glycogen Synthase Kinase 3 Beta Predicts Survival in Resected Adenocarcinoma of the Pancreas. PMID: 26240274 Ref: A combination of molecular markers and clinical features improve the classification of pancreatic cysts. PMID: 26253305 Ref: Quercetin Mediates beta-Catenin in Pancreatic Cancer Stem-Like Cells. PMID: 26284537 Ref: DKK3 blocked translocation of beta-catenin/EMT induced by hypoxia and improved gemcitabine therapeutic effect in pancreatic cancer Bxpc-3 cell. PMID: 26395974 Ref: Cantharidin and norcantharidin impair stemness of pancreatic cancer cells by repressing the beta-catenin pathway and strengthen the cytotoxicity of gemcitabine and erlotinib. PMID: 26398277 Ref: Fendiline inhibits proliferation and invasion of pancreatic cancer cells by interfering with ADAM10 activation and beta-catenin signaling. PMID: 26440150 Ref: Epigenetic changes and alternate promoter usage by human colon cancers for expressing DCLK1-isoforms: Clinical Implications. PMID: 26447334 Ref: Multifocal intraductal tubulopapillary neoplasm of the pancreas with total pancreatectomy: report of a case and review of literature. PMID: 26464736 Ref: Merlin/NF2 Suppresses Pancreatic Tumor Growth and Metastasis by Attenuating the FOXM1-Mediated Wnt/beta-Catenin Signaling. PMID: 26483206 Ref: EBP50 inhibits pancreatic cancer cell growth and invasion by targeting the beta-catenin/E-cadherin pathway. PMID: 26622484 Ref: Accuracy of diagnosis of solid pseudopapillary tumor of the pancreas on fine needle aspiration: A multi-institution experience of ten cases. PMID: 26884802 |
Ref: TRIM37 promoted the growth and migration of the pancreatic cancer cells. PMID: 26395261 Ref: N-cadherin functions as a growth suppressor in a model of K-ras-induced PanIN. PMID: 26477318 Ref: FHL2: a scaffold protein of carcinogenesis, tumour-stroma interactions and treatment response. PMID: 26676939 Ref: FOXC2 is up-regulated in pancreatic ductal adenocarcinoma and promotes the growth and migration of cancer cells. PMID: 26733175 Ref: PR55alpha Subunit of Protein Phosphatase 2A Supports the Tumorigenic and Metastatic Potential of Pancreatic Cancer Cells by Sustaining Hyperactive Oncogenic Signaling. PMID: 26893480 Ref: Loss of tumor suppressor Merlin results in aberrant activation of Wnt/beta-catenin signaling in cancer. PMID: 26908451 Ref: Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer. PMID: 27045006 Ref: Calcium sensing receptor suppresses human pancreatic tumorigenesis through a novel NCX1/Ca(2+)/beta-catenin signaling pathway. PMID: 27108064 Ref: Junctional Adhesion Molecule-A in Head and Neck Squamous Cell Carcinoma. PMID: 27115511 Ref: Membranous CD24 drives the epithelial phenotype of pancreatic cancer. PMID: 27203385 Ref: FH535, a beta-catenin pathway inhibitor, represses pancreatic cancer xenograft growth and angiogenesis. PMID: 27323403 Ref: Leukemia inhibitory factor receptor negatively regulates the metastasis of pancreatic cancer cells in vitro and in vivo. PMID: 27375070 Ref: Selective GPR55 antagonism reduces chemoresistance in cancer cells. PMID: 27423937 Ref: Inhibitory effect of RNA-mediated knockdown of zinc finger protein 91 pseudogene on pancreatic cancer cell growth and invasion. PMID: 27446435 Ref: Oridonin inhibits pancreatic cancer cell migration and epithelial-mesenchymal transition by suppressing Wnt/beta-catenin signaling pathway. PMID: 27453691 Ref: Over-expression of microRNA-940 promotes cell proliferation by targeting GSK3beta and sFRP1 in human pancreatic carcinoma. PMID: 27459115 Ref: Tumor suppressor Fbxw7 antagonizes WNT signaling by targeting beta-catenin for degradation in pancreatic cancer. PMID: 27485116 Ref: BCL9L expression in pancreatic neoplasia with a focus on SPN: a possible explanation for the enigma of the benign neoplasia. PMID: 27539223 Ref: Distinct pathways of pathogenesis of intraductal oncocytic papillary neoplasms and intraductal papillary mucinous neoplasms of the pancreas. PMID: 27591765 Ref: Effect of MUC1/beta-catenin interaction on the tumorigenic capacity of pancreatic CD133(+) cells. PMID: 27602113 Ref: Role of BCL9L in transforming growth factor-beta (TGF-beta)-induced epithelial-to-mesenchymal-transition (EMT) and metastasis of pancreatic cancer. PMID: 27713160 Ref: Downregulation of Smurf2 ubiquitin ligase in pancreatic cancer cells reversed TGF-beta-induced tumor formation. PMID: 27730540 Ref: Pancreatic neuroendocrine tumor and solid-pseudopapillary neoplasm: Key immunohistochemical profiles for differential diagnosis. PMID: 27784972 Ref: MicroRNA-182 promotes pancreatic cancer cell proliferation and migration by targeting beta-TrCP2. PMID: 27797718 Ref: The Wnt/beta-catenin signaling pathway mechanism for pancreatic cancer chemoresistance in a three-dimensional cancer microenvironment. PMID: 27830034 Ref: Activation of WNT/beta-Catenin Signaling Enhances Pancreatic Cancer Development and the Malignant Potential Via Up-regulation of Cyr61. PMID: 27889647 Ref: Nonductal Pancreatic Cancers. PMID: 27926361 Ref: The pattern of hMENA isoforms is regulated by TGF-beta1 in pancreatic cancer and may predict patient outcome. PMID: 28123868 Ref: Solid-Pseudopapillary neoplasm of the pancreas: A clinicopathological review of 20 cases including rare examples. PMID: 28327291 |
Ref: Histopathological tumor invasion of the mesenterico-portal vein is characterized by aggressive biology and stromal fibroblast activation. PMID: 27825542 Ref: Methyl-CpG-binding domain 3 inhibits epithelial-mesenchymal transition in pancreatic cancer cells via TGF-beta/Smad signalling. PMID: 27898661 Ref: Modulation of post-translational modifications in beta-catenin and LRP6 inhibits Wnt signaling pathway in pancreatic cancer. PMID: 27919787 Ref: Hormophysa triquerta polyphenol, an elixir that deters CXCR4- and COX2-dependent dissemination destiny of treatment-resistant pancreatic cancer cells. PMID: 27974694 Ref: Effect of NR5A2 inhibition on pancreatic cancer stem cell (CSC) properties and epithelial-mesenchymal transition (EMT) markers. PMID: 27996162 Ref: Somatic Genetic Variation in Solid Pseudopapillary Tumor of the Pancreas by Whole Exome Sequencing. PMID: 28054945 Ref: A Solid Pseudopapillary Neoplasm of the Pancreas Associated With IgG4-Related Pancreatitis: A Case Report. PMID: 28107092 Ref: FASN Inhibition and Taxane Treatment Combine to Enhance Anti-tumor Efficacy in Diverse Xenograft Tumor Models through Disruption of Tubulin Palmitoylation and Microtubule Organization and FASN Inhibition-Mediated Effects on Oncogenic Signaling and Gene Ex PMID: 28159572 Ref: MicroRNA-1285 inhibits malignant biological behaviors of human pancreatic cancer cells by negative regulation of YAP1. PMID: 28253715 Ref: [The clinical characteristics surgical procedures and prognosis of solid pseudopapillary tumor of the pancreas]. PMID: 28316222 Ref: Interleukin-9 Promotes Pancreatic Cancer Cells Proliferation and Migration via the miR-200a/Beta-Catenin Axis. PMID: 28349057 Ref: Pancreatic solitary fibrous tumor in a toddler managed by pancreaticoduodenectomy: a case report and review of the literature. PMID: 28392706 Ref: The regulation of beta-catenin activity and function in cancer: therapeutic opportunities. PMID: 28430641 Ref: YEATS4 promotes the tumorigenesis of pancreatic cancer by activating beta-catenin/TCF signaling. PMID: 28445953 Ref: ZNF281 Promotes Growth and Invasion of Pancreatic Cancer Cells by Activating Wnt/beta-Catenin Signaling. PMID: 28523575 Ref: MicroRNA-148a suppresses epithelial-mesenchymal transition and invasion of pancreatic cancer cells by targeting Wnt10b and inhibiting the Wnt/beta-catenin signaling pathway. PMID: 28586066 Ref: CHD1L Expression Increases Tumor Progression and Acts as a Predictive Biomarker for Poor Prognosis in Pancreatic Cancer. PMID: 28646284 Ref: Solid Pseudopapillary Tumor of the Pancreas: An Unusual Cause of Abdominal Pain. PMID: 28649475 Ref: Solid Pseudopapillary Neoplasm of the Pancreas: A Rare Entity With Unique Features. PMID: 28661210 Ref: Matrix stiffness induces epithelial-mesenchymal transition and promotes chemoresistance in pancreatic cancer cells. PMID: 28671675 Ref: Hypoxia-inducible factor-2alpha promotes tumor progression and has crosstalk with Wnt/beta-catenin signaling in pancreatic cancer. PMID: 28705232 Ref: Cyclin-dependent kinase 1 (CDK1)-mediated mitotic phosphorylation of the transcriptional co-repressor Vgll4 inhibits its tumor-suppressing activity. PMID: 28739871 Ref: GPR55 receptor antagonist decreases glycolytic activity in PANC-1 pancreatic cancer cell line and tumor xenografts. PMID: 28741686 Ref: The armadillo protein p0071 controls KIF3 motor transport. PMID: 28808088 Ref: Overexpression of miR-135b-5p promotes unfavorable clinical characteristics and poor prognosis via the repression of SFRP4 in pancreatic cancer. PMID: 28977937 Ref: TFCP2 activates beta-catenin/TCF signaling in the progression of pancreatic cancer. PMID: 29050300 Ref: Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway. PMID: 29072694 |
Ref: TOP2A induces malignant character of pancreatic cancer through activating beta-catenin signaling pathway. PMID: 29045811 Ref: Activation of PPARalpha by clofibrate sensitizes pancreatic cancer cells to radiation through the Wnt/beta-catenin pathway. PMID: 29059162 Ref: Integrated Molecular Characterization of the Lethal Pediatric Cancer Pancreatoblastoma. PMID: 29233928 Ref: CUL4B promotes metastasis and proliferation in pancreatic cancer cells by inducing epithelial-mesenchymal transition via the Wnt/beta-catenin signaling pathway. PMID: 29274277 Ref: Inhibiting beta-Catenin by beta-Carboline-Type MDM2 Inhibitor for Pancreatic Cancer Therapy. PMID: 29387014 Ref: Mechanisms by which CXCR4/CXCL12 cause metastatic behavior in pancreatic cancer. PMID: 29434873 Ref: TCF7L2 positively regulates aerobic glycolysis via the EGLN2/HIF-1alpha axis and indicates prognosis in pancreatic cancer. PMID: 29476053 Ref: Downregulated miR-23b-3p expression acts as a predictor of hepatocellular carcinoma progression: A study based on public data and RT-qPCR verification. PMID: 29484429 Ref: Differentiation Therapy Targeting the beta-Catenin/CBP Interaction in Pancreatic Cancer. PMID: 29596326 Ref: Salinomycin nanoparticles interfere with tumor cell growth and the tumor microenvironment in an orthotopic model of pancreatic cancer. PMID: 29619850 Ref: The Wnt-beta-catenin signaling regulated MRTF-A transcription to activate migration-related genes in human breast cancer cells. PMID: 29632640 Ref: MicroRNA-449a functions as a tumor suppressor in pancreatic cancer by the epigenetic regulation of ATDC expression. PMID: 29684857 Ref: Solid pseudopapillary neoplasm (SPN) of the testis: Comprehensive mutational analysis of 6 testicular and 8 pancreatic SPNs. PMID: 29705715 Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). PMID: 29786110 Ref: Extract of the Medicinal Plant Pao Pereira Inhibits Pancreatic Cancer Stem-Like Cell In Vitro and In Vivo. PMID: 29985062 Ref: Serous Neoplasms of the Pancreas: A Comprehensive Review. PMID: 30141993 Ref: Prior exposure of pancreatic tumors to [sorafenib + vorinostat] enhances the efficacy of an anti-PD-1 antibody. PMID: 30142009 Ref: Long non-coding RNA SUMO1P3 may promote cell proliferation, migration, and invasion of pancreatic cancer via EMT signaling pathway. PMID: 30333879 Ref: Silencing of Astrocyte elevated gene-1 (AEG-1) inhibits proliferation, migration and invasion, and promotes apoptosis in pancreatic cancer cells. PMID: 30359541 Ref: beta-Catenin expression is associated with cell invasiveness in pancreatic cancer. PMID: 30360026 Ref: Therapeutic potential of targeting the Wnt/beta-catenin pathway in the treatment of pancreatic cancer. PMID: 30368889 |