Primary Site >> Esophagus Cancer
Gene >> CTNNB1
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Ref: Beta-catenin expression in human cancers. PMID: 8546224 Ref: [Mechanism of the lymph node metastasis in human esophageal cancer (epidermal growth factor causes the dysfunction of cadherin-mediated cell-cell adhesion)]. PMID: 9183627 |
Ref: Expression of E-cadherin, alpha-catenin, beta-catenin and plakoglobin in esophageal carcinomas and its prognostic significance: immunohistochemical analysis of 96 lesions. PMID: 9075789 |
Ref: A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals. PMID: 9707618 |
Ref: Cytoplasmic beta-catenin in esophageal cancers. PMID: 10096251 |
Ref: Clinical application of malignancy potential grading as a prognostic factor of human esophageal cancers. PMID: 10819064 |
Ref: Alterations of frizzled (FzE3) and secreted frizzled related protein (hsFRP) expression in gastric cancer. PMID: 11798016 |
Ref: Wnt-1 but not epidermal growth factor induces beta-catenin/T-cell factor-dependent transcription in esophageal cancer cells. PMID: 11782388 Ref: Expression and regulation of WNT5A and WNT5B in human cancer: up-regulation of WNT5A by TNFalpha in MKN45 cells and up-regulation of WNT5B by beta-estradiol in MCF-7 cells. PMID: 12165812 Ref: Molecular and genetic characterization of a non-metastatic human esophageal cancer cell line, T.Tn expressing non-functional mutated p53. PMID: 12168098 Ref: Expression and regulation of WNT10B in human cancer: up-regulation of WNT10B in MCF-7 cells by beta-estradiol and down-regulation of WNT10B in NT2 cells by retinoic acid. PMID: 12239602 Ref: [Expression and significance of beta-catenin in esophageal carcinoma]. PMID: 12478897 Ref: Interrelation between expression of matrix metalloproteinase 7 and beta-catenin in esophageal cancer. PMID: 12498294 |
Ref: Down-regulation of beta catenin inhibits the growth of esophageal carcinoma cells. PMID: 14752418 Ref: [Immunohistochemical detection and clinical significance of beta-catenin expression in human esophageal cancers]. PMID: 15291105 Ref: Prognostic and clinicopathological features of E-cadherin, alpha-catenin, beta-catenin, gamma-catenin and cyclin D1 expression in human esophageal squamous cell carcinoma. PMID: 15484291 |
Ref: Overexpression of human pituitary tumor transforming gene (hPTTG), is regulated by beta-catenin /TCF pathway in human esophageal squamous cell carcinoma. PMID: 15514942 Ref: Detection of JC virus DNA sequences and expression of viral T antigen and agnoprotein in esophageal carcinoma. PMID: 15630684 Ref: Overexpression of EB1 in human esophageal squamous cell carcinoma (ESCC) may promote cellular growth by activating beta-catenin/TCF pathway. PMID: 16007168 Ref: beta-Catenin splice variants and downstream targets as markers for neoplastic progression of esophageal cancer. PMID: 16114033 Ref: Role of fascin in the proliferation and invasiveness of esophageal carcinoma cells. PMID: 16185662 Ref: WNT2B: comparative integromics and clinical applications (Review). PMID: 16273293 |
Ref: Met receptor signaling: a key effector in esophageal adenocarcinoma. PMID: 17062664 |
Ref: Aberrant nuclear localization of beta-catenin without genetic alterations in beta-catenin or Axin genes in esophageal cancer. PMID: 17309796 Ref: The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas. PMID: 17384664 Ref: Expression level of beta-catenin is associated with prognosis of esophageal carcinoma. PMID: 17552014 Ref: The Association of Beta-catenin Gene Mutations and Human Papillomavirus in Carcinoma of Esophagus in a High-Risk Population of India. PMID: 21475426 |
Ref: Genomic profiling of 766 cancer-related genes in archived esophageal normal and carcinoma tissues. PMID: 18241037 Ref: FRAT1 overexpression leads to aberrant activation of beta-catenin/TCF pathway in esophageal squamous cell carcinoma. PMID: 18498136 Ref: beta-Catenin/TCF pathway upregulates STAT3 expression in human esophageal squamous cell carcinoma. PMID: 18602747 Ref: Lithium inhibits proliferation of human esophageal cancer cell line Eca-109 by inducing a G2/M cell cycle arrest. PMID: 18609681 Ref: Inhibition of alpha-mannosidase Man2c1 gene expression suppresses growth of esophageal carcinoma cells through mitotic arrest and apoptosis. PMID: 19018777 |
Ref: Isolation and identification of cancer stem-like cells in esophageal carcinoma cell lines. PMID: 18680391 Ref: Disruption of xCT inhibits cancer cell metastasis via the caveolin-1/beta-catenin pathway. PMID: 19015640 Ref: Gene silencing of beta-catenin by RNAi inhibits cell proliferation in human esophageal cancer cells in vitro and in nude mice. PMID: 19021690 |
Ref: Overexpression of a novel gene gankyrin correlates with the malignant phenotype of colorectal cancer. PMID: 19901563 Ref: Loss of p53, rather than beta-catenin overexpression, induces survivin-mediated resistance to apoptosis in an esophageal cancer cell line. PMID: 20236666 Ref: Wnt inhibitor Dickkopf-1 as a target for passive cancer immunotherapy. PMID: 20551066 Ref: Identification of differentially expressed genes related to radioresistance of human esophageal cancer cells. PMID: 20868558 Ref: [Effect of beta-catenin gene silencing by shRNA on biologic characteristics of human esophageal carcinoma cells]. PMID: 21215100 |
Ref: Characterization of tumor-suppressive function of SOX6 in human esophageal squamous cell carcinoma. PMID: 21084391 Ref: The radiosensitization effect of NS398 on esophageal cancer stem cell-like radioresistant cells. PMID: 21087344 Ref: The dichotomy in carcinogenesis of the distal esophagus and esophagogastric junction: intestinal-type vs cardiac-type mucosa-associated adenocarcinoma. PMID: 21572404 Ref: PLK1 Is transcriptionally activated by NF-kappaB during cell detachment and enhances anoikis resistance through inhibiting beta-catenin degradation in esophageal squamous cell carcinoma. PMID: 21610149 Ref: The flavonoid Baohuoside-I inhibits cell growth and downregulates survivin and cyclin D1 expression in esophageal carcinoma via beta-catenin-dependent signaling. PMID: 21785828 |
Ref: Clear cell variant of squamous cell carcinoma originating in the esophagus: report of a case with immunohistochemical and oncogenetic analyses. PMID: 22243784 Ref: Migfilin regulates esophageal cancer cell motility through promoting GSK-3beta-mediated degradation of beta-catenin. PMID: 22246236 Ref: Identification of PTK6, via RNA sequencing analysis, as a suppressor of esophageal squamous cell carcinoma. PMID: 22705009 Ref: High-throughput genotyping in metastatic esophageal squamous cell carcinoma identifies phosphoinositide-3-kinase and BRAF mutations. PMID: 22870241 Ref: Inhibition of SOX17 by microRNA 141 and methylation activates the WNT signaling pathway in esophageal cancer. PMID: 22921431 Ref: Gene silencing of beta-catenin by RNAi inhibits proliferation of human esophageal cancer cells by inducing G0/G1 cell cycle arrest. PMID: 22938416 |
Ref: Physiological beta-catenin signaling controls self-renewal networks and generation of stem-like cells from nasopharyngeal carcinoma. PMID: 24073846 |
Ref: Inhibition of atypical protein kinase Ciota induces apoptosis through autophagic degradation of beta-catenin in esophageal cancer cells. PMID: 23359356 Ref: The tumor suppressor LKB1 antagonizes WNT signaling pathway through modulating GSK3beta activity in cell growth of esophageal carcinoma. PMID: 24022664 Ref: The role of glycogen synthase kinase 3-beta in immunity and cell cycle: implications in esophageal cancer. PMID: 24276788 Ref: Mesenchymal phenotype after chemotherapy is associated with chemoresistance and poor clinical outcome in esophageal cancer. PMID: 24297447 Ref: Down-regulated gamma-catenin expression is associated with tumor aggressiveness in esophageal cancer. PMID: 24914344 Ref: Expression of migfilin is increased in esophageal cancer and represses the Akt-beta-catenin activation. PMID: 24959381 Ref: Telomerase variant A279T induces telomere dysfunction and inhibits non-canonical telomerase activity in esophageal carcinomas. PMID: 24983628 Ref: Prognostic significance of beta-catenin expression in patients with esophageal carcinoma: a meta-analysis. PMID: 25124581 Ref: SOX10, a novel HMG-box-containing tumor suppressor, inhibits growth and metastasis of digestive cancers by suppressing the Wnt/beta-catenin pathway. PMID: 25301735 Ref: MicroRNA-9 promotes tumor metastasis via repressing E-cadherin in esophageal squamous cell carcinoma. PMID: 25375090 |
Ref: Expression and Splice Variant Analysis of Human TCF4 Transcription Factor in Esophageal Cancer. PMID: 25767603 Ref: FH535 increases the radiosensitivity and reverses epithelial-to-mesenchymal transition of radioresistant esophageal cancer cell line KYSE-150R. PMID: 25888911 Ref: Clinicopathological significance of wnt/beta-catenin signaling pathway in esophageal squamous cell carcinoma. PMID: 26045816 Ref: [Anti-metastasis of celastrol on esophageal cancer cells and its mechanism]. PMID: 26109308 Ref: Nuclear Localization of DNAJB6 Is Associated With Survival of Patients With Esophageal Cancer and Reduces AKT Signaling and Proliferation of Cancer Cells. PMID: 26302489 Ref: Molecular Marker Expression Is Highly Heterogeneous in Esophageal Adenocarcinoma and Does Not Predict a Response to Neoadjuvant Therapy. PMID: 26394876 Ref: Esophageal Cancer Epigenomics and Integrome Analysis of Genome-Wide Methylation and Expression in High Risk Northeast Indian Population. PMID: 26496483 Ref: Regulation of beta-catenin-mediated esophageal cancer growth and invasion by miR-214. PMID: 26807179 |
Ref: Heterophyllin B inhibits the adhesion and invasion of ECA-109 human esophageal carcinoma cells by targeting PI3K/AKT/beta-catenin signaling. PMID: 26647768 Ref: Identification of novel NRAGE involved in the radioresistance of esophageal cancer cells. PMID: 26738870 Ref: Long noncoding RNA MALAT1 promotes malignant development of esophageal squamous cell carcinoma by targeting beta-catenin via Ezh2. PMID: 27015363 Ref: lncRNA UCA1 inhibits esophageal squamous-cell carcinoma growth by regulating the Wnt signaling pathway. PMID: 27267823 Ref: NDRG1 overexpression promotes the progression of esophageal squamous cell carcinoma through modulating Wnt signaling pathway. PMID: 27414086 Ref: Decreased expression of CDH1 or CTNNB1 affects poor prognosis of patients with esophageal cancer. PMID: 27600761 Ref: Reversal effect of ouabain on multidrug resistance in esophageal carcinoma EC109/CDDP cells by inhibiting the translocation of Wnt/beta-catenin into the nucleus. PMID: 27709549 Ref: Valproic acid inhibits irradiation-induced epithelial-mesenchymal transition and stem cell-like characteristics in esophageal squamous cell carcinoma. PMID: 27826618 |
Ref: Knockdown of DDX5 Inhibits the Proliferation and Tumorigenesis in Esophageal Cancer. PMID: 28244855 Ref: The Prolyl Isomerase Pin1 Is a Novel Target of 6,7,4'-Trihydroxyisoflavone for Suppressing Esophageal Cancer Growth. PMID: 28325828 Ref: Inhibition of LSD1 epigenetically attenuates oral cancer growth and metastasis. PMID: 29088714 |
Ref: Exosomes Derived from Irradiated Esophageal Carcinoma-Infiltrating T Cells Promote Metastasis by Inducing the Epithelial-Mesenchymal Transition in Esophageal Cancer Cells. PMID: 28132116 Ref: Over-expression of oncigenic pesudogene DUXAP10 promotes cell proliferation and invasion by regulating LATS1 and beta-catenin in gastric cancer. PMID: 29374493 Ref: Gli is activated and promotes epithelial-mesenchymal transition in human esophageal adenocarcinoma. PMID: 29416661 |