Primary Site >> Colorectal Cancer

Gene >> CTNNA1

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Ref: alpha-Catenin-vinculin interaction functions to organize the apical junctional complex in epithelial cells.
PMID: 9700171
Ref: Dysregulation of the E-cadherin/catenin complex by irreversible mutations in human carcinomas.
PMID: 9823469
Ref: The alphaE-catenin gene (CTNNA1) acts as an invasion-suppressor gene in human colon cancer cells.
PMID: 10023666
Ref: The role of the E-cadherin/catenin complex in gastrointestinal cancer.
PMID: 10692769
Ref: hMSH6 deficiency and inactivation of the alphaE-catenin invasion-suppressor gene in HCT-8 colon cancer cells.
PMID: 10919711
Ref: alphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion.
PMID: 11590244
Ref: [Allelic analysis on chromosome 5 in sporadic colorectal cancer patients].
PMID: 12485498
Ref: Alpha-catenin is required for IGF-I-induced cellular migration but not invasion in human colonic cancer cells.
PMID: 14961074
Ref: The penetration of anticancer drugs through tumor tissue as a function of cellular adhesion and packing density of tumor cells.
PMID: 16424039
Ref: Truncated isoform of mouse alphaT-catenin is testis-restricted in expression and function.
PMID: 17185752
Ref: Alpha-catenin is essential in intestinal adenoma formation.
PMID: 17989230
Ref: Genetic variations of the CTNNA1 and the CTNNB1 genes in sporadic colorectal cancer in Polish population.
PMID: 23399619
Ref: MiR-429 inhibits cells growth and invasion and regulates EMT-related marker genes by targeting Onecut2 in colorectal carcinoma.
PMID: 24402783
Ref: Downregulated pseudogene CTNNAP1 promote tumor growth in human cancer by downregulating its cognate gene CTNNA1 expression.
PMID: 27487124
Ref: Appendiceal goblet cell carcinoids and adenocarcinomas ex-goblet cell carcinoid are genetically distinct from primary colorectal-type adenocarcinoma of the appendix.
PMID: 29327707