Primary Site >> Biliary tract Cancer

Gene >> CTGF

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Ref: Serial analysis of gene expression identifies connective tissue growth factor expression as a prognostic biomarker in gallbladder cancer.
PMID: 18451226
Ref: beta-Adrenoceptor blockade in sclerosing cholangitis of Mdr2 knockout mice: antifibrotic effects in a model of nonsinusoidal fibrosis.
PMID: 20921947
Ref: Transforming growth factor-beta signaling promotes hepatocarcinogenesis induced by p53 loss.
PMID: 21898503
Ref: Deregulation of Hippo kinase signalling in human hepatic malignancies.
PMID: 22098159
Ref: Targeting PDGFR-beta in Cholangiocarcinoma.
PMID: 22133064
Ref: Connective tissue growth factor immunohistochemical expression is associated with gallbladder cancer progression.
PMID: 23368866
Ref: Inhibition of connective tissue growth factor (CTGF/CCN2) in gallbladder cancer cells leads to decreased growth in vitro.
PMID: 23593935
Ref: Connective tissue growth factor and integrin alphavbeta6: a new pair of regulators critical for ductular reaction and biliary fibrosis in mice.
PMID: 25203810
Ref: Dysregulated YAP1/TAZ and TGF-beta signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice.
PMID: 26699479
Ref: Members of the Cyr61/CTGF/NOV Protein Family: Emerging Players in Hepatic Progenitor Cell Activation and Intrahepatic Cholangiocarcinoma.
PMID: 27829832