Primary Site >> Colorectal Cancer

Gene >> CTBP2

  • 2006
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  • 2017
Ref: Targeting of C-terminal binding protein (CtBP) by ARF results in p53-independent apoptosis.
PMID: 16508011
Ref: The alternative reading frame tumor suppressor antagonizes hypoxia-induced cancer cell migration via interaction with the COOH-terminal binding protein corepressor.
PMID: 17909040
Ref: An ARF/CtBP2 complex regulates BH3-only gene expression and p53-independent apoptosis.
PMID: 19798104
Ref: Inhibition of C-terminal binding protein attenuates transcription factor 4 signaling to selectively target colon cancer stem cells.
PMID: 25483087
Ref: Expression and prognostic significance of CTBP2 in human gliomas.
PMID: 27698809
Ref: Transforming activity and therapeutic targeting of C-terminal-binding protein 2 in Apc-mutated neoplasia.
PMID: 28414304