Primary Site >> Colorectal Cancer
Gene >> CSK
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Ref: Elevated c-Src tyrosine kinase activity in premalignant epithelia of ulcerative colitis. PMID: 7509341 Ref: Identification of a novel variant form of fibroblast growth factor receptor 3 (FGFR3 IIIb) in human colonic epithelium. PMID: 7923141 |
Ref: Expression of C-terminal src kinase in human colorectal cancer cell lines. PMID: 7533218 Ref: Src phosphorylation of the epidermal growth factor receptor at novel sites mediates receptor interaction with Src and P85 alpha. PMID: 7797556 Ref: Abnormal cell proliferation and p52/p35-CSK expression in the colons of aging rats. PMID: 8557097 |
Ref: Ubiquitin-dependent degradation of active Src. PMID: 10508617 |
Ref: Overexpression of the csk gene suppresses tumor metastasis in vivo. PMID: 11054667 |
Ref: Reduced C-terminal Src kinase activity is correlated inversely with pp60(c-src) activity in colorectal carcinoma. PMID: 11443610 |
Ref: Csk defines the ability of integrin-mediated cell adhesion and migration in human colon cancer cells: implication for a potential role in cancer metastasis. PMID: 14712234 |
Ref: Down-regulation of the tumor suppressor gene C-terminal Src kinase: an early event during premalignant colonic epithelial hyperproliferation. PMID: 15961079 |
Ref: PRL3 promotes cell invasion and proliferation by down-regulation of Csk leading to Src activation. PMID: 17192274 Ref: PTP1B contributes to the oncogenic properties of colon cancer cells through Src activation. PMID: 17974954 |
Ref: Antiproliferative effect of sulindac in colonic neoplasia prevention: role of COOH-terminal Src kinase. PMID: 18644992 |
Ref: Src family tyrosine kinases-driven colon cancer cell invasion is induced by Csk membrane delocalization. PMID: 20010872 Ref: p140Cap dual regulation of E-cadherin/EGFR cross-talk and Ras signalling in tumour cell scatter and proliferation. PMID: 20453886 Ref: Role of cytoskeleton in controlling the disorder strength of cellular nanoscale architecture. PMID: 20682278 Ref: Purvalanol A, a CDK inhibitor, effectively suppresses Src-mediated transformation by inhibiting both CDKs and c-Src. PMID: 20825494 |
Ref: Epithelial cells augment barrier function via activation of the Toll-like receptor 2/phosphatidylinositol 3-kinase pathway upon recognition of Salmonella enterica serovar Typhimurium curli fibrils in the gut. PMID: 23208603 Ref: Chemopreventive activity of plant flavonoid isorhamnetin in colorectal cancer is mediated by oncogenic Src and beta-catenin. PMID: 23824743 |
Ref: Drosophila C-terminal Src kinase regulates growth via the Hippo signaling pathway. PMID: 25446534 |
Ref: Overexpression of Srcin1 contributes to the growth and metastasis of colorectal cancer. PMID: 28393242 Ref: Csk-homologous kinase (Chk) is an efficient inhibitor of Src-family kinases but a poor catalyst of phosphorylation of their C-terminal regulatory tyrosine. PMID: 28784162 |
Ref: Role of Csk in intestinal epithelial barrier function and protection against colitis. PMID: 30173891 |