Primary Site >> Colorectal Cancer

Gene >> CRTC1

  • 2012
  • 2014
  • 2016
  • 2017
Ref: Pharmacological control of autophagy: therapeutic perspectives in inflammatory bowel disease and colorectal cancer.
PMID: 22632751
Ref: mTOR inhibition specifically sensitizes colorectal cancers with KRAS or BRAF mutations to BCL-2/BCL-XL inhibition by suppressing MCL-1.
PMID: 24163374
Ref: Dysregulated CRTC1 activity is a novel component of PGE2 signaling that contributes to colon cancer growth.
PMID: 26300003
Ref: Effective targeting of colorectal cancer cells using TORC1/2 kinase inhibitors in vitro and in vivo.
PMID: 26776341
Ref: Nesfatin-1/Nucleobindin-2 enhances cell migration, invasion, and epithelial-mesenchymal transition via LKB1/AMPK/TORC1/ZEB1 pathways in colon cancer.
PMID: 27150059
Ref: Multilevel genomics of colorectal cancers with microsatellite instability-clinical impact of JAK1 mutations and consensus molecular subtype 1.
PMID: 28539123