Primary Site >> Colorectal Cancer
Gene >> CREBBP
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Ref: Conjunction dysfunction: CBP/p300 in human disease. PMID: 9613201 |
Ref: beta-catenin signaling and cancer. PMID: 10580987 |
Ref: Regulation of interleukin-6 gene expression by pro-inflammatory cytokines in a colon cancer cell line. PMID: 10903137 |
Ref: The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation. PMID: 11532957 Ref: Inactivation of p21 by E1A leads to the induction of apoptosis in DNA-damaged cells. PMID: 11559818 |
Ref: Transcriptional deregulation of the keratin 18 gene in human colon carcinoma cells results from an altered acetylation mechanism. PMID: 12140315 Ref: Role of coactivators and corepressors in the induction of the RARbeta gene in human colon cancer cells. PMID: 12392082 |
Ref: Nemo-like kinase suppresses a wide range of transcription factors, including nuclear factor-kappaB. PMID: 14720327 Ref: A role for p300/CREB binding protein genes in promoting cancer progression in colon cancer cell lines with microsatellite instability. PMID: 14732695 Ref: Polyoma enhancer activator 3, an ets transcription factor, mediates the induction of cyclooxygenase-2 by nitric oxide in colorectal cancer cells. PMID: 14976201 Ref: Targets of 17beta-oestradiol-induced apoptosis in colon cancer cells: a mechanism for the protective effects of hormone replacement therapy? PMID: 15128281 |
Ref: Ciglitazone induces early cellular proliferation and NF-kappaB transcriptional activity in colon cancer cells through p65 phosphorylation. PMID: 15618021 Ref: Differential roles for the coactivators CBP and p300 on TCF/beta-catenin-mediated survivin gene expression. PMID: 15782138 |
Ref: CBP/p300 are bimodal regulators of Wnt signaling. PMID: 17410209 Ref: Expression of HDAC1 and CBP/p300 in human colorectal carcinomas. PMID: 17720775 Ref: Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation. PMID: 17908689 Ref: A role for CITED2, a CBP/p300 interacting protein, in colon cancer cell invasion. PMID: 18054336 |
Ref: Interactions between XIAP associated factor 1 and a nuclear co-activator, CBP, in colon cancer cells. PMID: 18362468 |
Ref: Preferential induction of EphB4 over EphB2 and its implication in colorectal cancer progression. PMID: 19366806 Ref: The transcriptional activity of Pygopus is enhanced by its interaction with cAMP-response-element-binding protein (CREB)-binding protein. PMID: 19555349 Ref: [Tissue microarray (TMA) validated progression markers in colorectal cancer using antibody microarrays]. PMID: 19648079 |
Ref: KLF4 interacts with beta-catenin/TCF4 and blocks p300/CBP recruitment by beta-catenin. PMID: 19901072 Ref: Nonsense mediated decay resistant mutations are a source of expressed mutant proteins in colon cancer cell lines with microsatellite instability. PMID: 21209843 |
Ref: Rational design of cyclic peptide modulators of the transcriptional coactivator CBP: a new class of p53 inhibitors. PMID: 21271695 Ref: HDAC inhibition decreases the expression of EGFR in colorectal cancer cells. PMID: 21464950 |
Ref: Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently suppresses dextran sulfate sodium-induced colitis and colon tumorigenesis in mice. PMID: 22409325 |
Ref: Corepressors (NCoR and SMRT) as well as coactivators are recruited to positively regulated 1alpha,25-dihydroxyvitamin D3-responsive genes. PMID: 22944139 Ref: CBP Activity Mediates Effects of the Histone Deacetylase Inhibitor Butyrate on WNT Activity and Apoptosis in Colon Cancer Cells. PMID: 23901348 Ref: p300 Influences Butyrate-Mediated WNT Hyperactivation In Colorectal Cancer Cells. PMID: 23901349 |
Ref: Modulation of Wnt Activity and Cell Physiology by Butyrate in LT97 Microadenoma Cells. PMID: 24563675 Ref: Thymine DNA glycosylase promotes transactivation of beta-catenin/TCFs by cooperating with CBP. PMID: 24748645 Ref: Safely targeting cancer stem cells via selective catenin coactivator antagonism. PMID: 24975284 Ref: The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth. PMID: 25082960 |
Ref: miRNA-26b Overexpression in Ulcerative Colitis-associated Carcinogenesis. PMID: 26083618 Ref: Acetylation-dependent function of human single-stranded DNA binding protein 1. PMID: 26170237 Ref: Screening of potential diagnostic markers and therapeutic targets against colorectal cancer. PMID: 26185457 Ref: Altering cancer transcriptomes using epigenomic inhibitors. PMID: 26191083 Ref: CREB-binding protein, p300, butyrate, and Wnt signaling in colorectal cancer. PMID: 26217075 Ref: Therapeutic targets in the Wnt signaling pathway: Feasibility of targeting TNIK in colorectal cancer. PMID: 26542362 |
Ref: Epigenetic regulation of E-cadherin expression by the histone demethylase UTX in colon cancer cells. PMID: 26819089 Ref: Bioinformatic exploration of MTA1-regulated gene networks in colon cancer. PMID: 27052252 Ref: Microarray Expression Data Identify DCC as a Candidate Gene for Early Meningioma Progression. PMID: 27096627 Ref: Determination of the Role of CBP- and p300-Mediated Wnt Signaling on Colonic Cells. PMID: 27177606 Ref: Somatic mutation detection using various targeted detection assays in paired samples of circulating tumor DNA, primary tumor and metastases from patients undergoing resection of colorectal liver metastases. PMID: 28949453 |
Ref: CIL-102-Induced Cell Cycle Arrest and Apoptosis in Colorectal Cancer Cells via Upregulation of p21 and GADD45. PMID: 28068431 Ref: 5-Fluorouracil targets histone acetyltransferases p300/CBP in the treatment of colorectal cancer. PMID: 28465257 Ref: ZEB1 Mediates Drug Resistance and EMT in p300-Deficient CRC. PMID: 28638460 Ref: Expression and role of nuclear receptor coregulators in colorectal cancer. PMID: 28740336 |
Ref: Benign and malignant tumors in Rubinstein-Taybi syndrome. PMID: 29359884 Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). PMID: 29786110 |