Primary Site >> Colorectal Cancer

Gene >> COPS8

  • 2009
  • 2012
  • 2014
  • 2015
  • 2016
  • 2017
Ref: The COP9 signalosome mediates beta-catenin degradation by deneddylation and blocks adenomatous polyposis coli destruction via USP15.
PMID: 19576224
Ref: Role of CSN5/JAB1 in Wnt/beta-catenin activation in colorectal cancer cells.
PMID: 22668871
Ref: Can hyperthermic intraperitoneal chemotherapy efficiency be improved by blocking the DNA repair factor COP9 signalosome?
PMID: 24728517
Ref: ERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer Development.
PMID: 26267535
Ref: Quercetin-induced apoptosis of HT-29 colon cancer cells via inhibition of the Akt-CSN6-Myc signaling axis.
PMID: 27748879
Ref: CSN5/JAB1 suppresses the WNT inhibitor DKK1 in colorectal cancer cells.
PMID: 28229932