Primary Site >> Colorectal Cancer

Gene >> COPS5

  • 2010
  • 2012
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  • 2015
  • 2017
  • 2018
Ref: The MIF homologue D-dopachrome tautomerase promotes COX-2 expression through beta-catenin-dependent and -independent mechanisms.
PMID: 21071513
Ref: Role of CSN5/JAB1 in Wnt/beta-catenin activation in colorectal cancer cells.
PMID: 22668871
Ref: JAB1 regulates unphosphorylated STAT3 DNA-binding activity through protein-protein interaction in human colon cancer cells.
PMID: 23911788
Ref: [Expression and significance of c-Jun activation domain binding protein 1 in human colorectal carcinoma].
PMID: 24854908
Ref: The beta-catenin E3 ubiquitin ligase SIAH-1 is regulated by CSN5/JAB1 in CRC cells.
PMID: 24882689
Ref: CSN5 silencing inhibits invasion and arrests cell cycle progression in human colorectal cancer SW480 and LS174T cells in vitro.
PMID: 26045788
Ref: HIF1alpha-Induced by Lysophosphatidic Acid Is Stabilized via Interaction with MIF and CSN5.
PMID: 26352431
Ref: Stat3 contributes to cancer progression by regulating Jab1/Csn5 expression.
PMID: 27524414
Ref: CSN5/JAB1 suppresses the WNT inhibitor DKK1 in colorectal cancer cells.
PMID: 28229932
Ref: JAB1-STAT3 activation loop is associated with recurrence following 5-fluorouracil-based adjuvant chemotherapy in human colorectal cancer.
PMID: 29113268
Ref: COPS5 and LASP1 synergistically interact to downregulate 14-3-3sigma expression and promote colorectal cancer progression via activating PI3K/AKT pathway.
PMID: 29226323