Primary Site >> Colorectal Cancer
Gene >> CNR1
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Ref: Anandamide is an endogenous inhibitor for the migration of tumor cells and T lymphocytes. PMID: 15034673 |
Ref: Cannabinoids and the digestive tract. PMID: 16596788 |
Ref: Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P. PMID: 16423891 |
Ref: The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells. PMID: 17583570 |
Ref: Long term cannabinoid receptor (CB1) blockade in obesity: implications for the development of colorectal cancer. PMID: 18076045 Ref: Reply to the letter to the editor "Long-term cannabinoid receptor (CB1) blockade in obesity: implications for the development of colorectal cancer". PMID: 18395892 Ref: Loss of cannabinoid receptor 1 accelerates intestinal tumor growth. PMID: 18676872 Ref: Estrogenic induction of cannabinoid CB1 receptor in human colon cancer cell lines. PMID: 18938775 Ref: Cannabinoid receptor activation induces apoptosis through tumor necrosis factor alpha-mediated ceramide de novo synthesis in colon cancer cells. PMID: 19047095 |
Ref: Single nucleotide change in the cannabinoid receptor-1 (CNR1) gene in colorectal cancer outcome. PMID: 19420965 Ref: Rimonabant inhibits human colon cancer cell growth and reduces the formation of precancerous lesions in the mouse colon. PMID: 19479993 |
Ref: Synergistic inhibition of human colon cancer cell growth by the cannabinoid CB1 receptor antagonist rimonabant and oxaliplatin. PMID: 19956878 Ref: The endogenous cannabinoid, anandamide, induces COX-2-dependent cell death in apoptosis-resistant colon cancer cells. PMID: 20514410 Ref: Effects of anandamide on polyamine levels and cell growth in human colon cancer cells. PMID: 20682986 |
Ref: Concerted action of CB1 cannabinoid receptor and deleted in colorectal cancer in axon guidance. PMID: 21273433 Ref: [Anandamide inhibits the growth of colorectal cancer cells through CB1 and lipid rafts]. PMID: 21575494 Ref: High tumour cannabinoid CB1 receptor immunoreactivity negatively impacts disease-specific survival in stage II microsatellite stable colorectal cancer. PMID: 21901119 Ref: Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent. PMID: 22110202 |
Ref: Interaction of endocannabinoid system and steroid hormones in the control of colon cancer cell growth. PMID: 21412772 |
Ref: Expression of the cannabinoid type I receptor and prognosis following surgery in colorectal cancer. PMID: 23426698 Ref: Cannabinoid receptor CB2 modulates axon guidance. PMID: 23951024 |
Ref: Inhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of cannabidiol. PMID: 24373545 Ref: Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid. PMID: 25269802 |
Ref: Extravirgin olive oil up-regulates CB(1) tumor suppressor gene in human colon cancer cells and in rat colon via epigenetic mechanisms. PMID: 25533906 Ref: Anti Proliferative and Pro Apoptotic Effects of Flavonoid Quercetin Are Mediated by CB1 Receptor in Human Colon Cancer Cell Lines. PMID: 25893829 Ref: The Antitumor Activity of Plant-Derived Non-Psychoactive Cannabinoids. PMID: 25916739 Ref: Endocannabinoid and ceramide levels are altered in patients with colorectal cancer. PMID: 25975960 |
Ref: Power of screening tests for colorectal cancer enhanced by high levels of M2-PK in addition to FOBT. PMID: 28155016 Ref: Dietary omega-3 Polyunsaturated Fatty Acids Inhibit Tumor Growth in Transgenic Apc(Min/+) Mice, Correlating with CB1 Receptor Up-Regulation. PMID: 28245562 Ref: Fatty acid amide hydrolase (FAAH) inhibitor PF-3845 reduces viability, migration and invasiveness of human colon adenocarcinoma Colo-205 cell line: an in vitro study. PMID: 28850633 |
Ref: G protein-coupled receptor GPR55 promotes colorectal cancer and has opposing effects to cannabinoid receptor 1. PMID: 28875496 Ref: miR1273g3p promotes proliferation, migration and invasion of LoVo cells via cannabinoid receptor 1 through activation of ERBB4/PIK3R3/mTOR/S6K2 signaling pathway. PMID: 29328379 Ref: Cannabinoid Receptor-1 Up-regulation in Azoxymethane (AOM)-treated Mice After Dietary Treatment with Quercetin. PMID: 30061214 |