Primary Site >> Colorectal Cancer
Gene >> CLOCK
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Ref: A strategy to discover circulating angiogenesis inhibitors generated by human tumors. PMID: 7545537 |
Ref: Cancer chronotherapy: principles, applications, and perspectives. PMID: 12491517 Ref: Chronotherapy for cancer. PMID: 14572683 Ref: Changes in toxicity and effectiveness with timing of drug administration: implications for drug safety. PMID: 14583062 |
Ref: Beta-catenin and cyclin D1: connecting development to breast cancer. PMID: 14712077 |
Ref: Human intestinal circadian clock: expression of clock genes in colonocytes lining the crypt. PMID: 16393700 |
Ref: Mutational dynamics in human tumors confirm the neutral intrinsic instability of the mitochondrial D-loop poly-cytidine repeat. PMID: 16708351 Ref: When does MMR loss occur during HNPCC progression? PMID: 17192057 |
Ref: Circadian rhythms in the CNS and peripheral clock disorders: chronopharmacological findings on antitumor drugs. PMID: 17299245 Ref: Implications of circadian clocks for the rhythmic delivery of cancer therapeutics. PMID: 17692427 Ref: Regulation of genes of the circadian clock in human colon cancer: reduced period-1 and dihydropyrimidine dehydrogenase transcription correlates in high-grade tumors. PMID: 17699798 Ref: Telomerase activation in neoplastic cell immortalization and tumour progression. PMID: 19105326 |
Ref: Period 2 mutation accelerates ApcMin/+ tumorigenesis. PMID: 19010825 |
Ref: Beta-catenin induces beta-TrCP-mediated PER2 degradation altering circadian clock gene expression in intestinal mucosa of ApcMin/+ mice. PMID: 19106159 Ref: Global co-distribution of light at night (LAN) and cancers of prostate, colon, and lung in men. PMID: 19142761 Ref: Correlated downregulation of estrogen receptor beta and the circadian clock gene Per1 in human colorectal cancer. PMID: 19148895 Ref: Clock genes and cancer. PMID: 20042409 |
Ref: Patient clock drawing and accuracy of self-report compared with chart review for colorectal cancer (CRC) screening. PMID: 19573932 Ref: Mutations in the circadian gene CLOCK in colorectal cancer. PMID: 20551151 Ref: Circadian rhythm of transferrin receptor 1 gene expression controlled by c-Myc in colon cancer-bearing mice. PMID: 20631077 Ref: Using DNA methylation patterns to infer tumor ancestry. PMID: 20711251 |
Ref: Expression of circadian genes correlates with liver metastasis and outcomes in colorectal cancer. PMID: 21380491 Ref: A combined experimental and mathematical approach for molecular-based optimization of irinotecan circadian delivery. PMID: 21931543 Ref: Clock gene expression levels and relationship with clinical and pathological features in colorectal cancer patients. PMID: 22080729 Ref: Expression of circadian clock gene human Period2 (hPer2) in human colorectal carcinoma. PMID: 22166120 Ref: Decreased expression of the melatonin receptor 1 in human colorectal adenocarcinomas. PMID: 22217986 |
Ref: Functional polymorphisms of circadian positive feedback regulation genes and clinical outcome of Chinese patients with resected colorectal cancer. PMID: 21773969 Ref: SIRT1 and the clock gene machinery in colorectal cancer. PMID: 22149272 Ref: Circadian regulation of the hepatic endobiotic and xenobitoic detoxification pathways: the time matters. PMID: 22303888 |
Ref: An association between clock genes and clock-controlled cell cycle genes in murine colorectal tumors. PMID: 22865596 Ref: Cryptochrome 1 overexpression correlates with tumor progression and poor prognosis in patients with colorectal cancer. PMID: 23626715 Ref: Expression of clock genes in patients with colorectal cancer. PMID: 23712462 Ref: hClock gene expression in human colorectal carcinoma. PMID: 23970287 Ref: Association of the clock genes polymorphisms with colorectal cancer susceptibility. PMID: 24037774 Ref: Expression of cell cycle regulatory factors hus1, gadd45a, rb1, cdkn2a and mre11a correlates with expression of clock gene per2 in human colorectal carcinoma tissue. PMID: 24062075 Ref: A circadian clock transcription model for the personalization of cancer chronotherapy. PMID: 24154875 Ref: [Chrono-drug delivery system based on the circadian rhythm of transferrin receptor]. PMID: 24437279 |
Ref: Overexpression of the circadian clock gene Bmal1 increases sensitivity to oxaliplatin in colorectal cancer. PMID: 24277452 Ref: Clock genes: their role in colorectal cancer. PMID: 24587674 Ref: Circadian clock circuitry in colorectal cancer. PMID: 24764658 Ref: Wrist actimetry circadian rhythm as a robust predictor of colorectal cancer patients survival. PMID: 24927369 |
Ref: Colorectal liver metastases with a disrupted circadian rhythm phase shift the peripheral clock in liver and kidney. PMID: 25045881 Ref: Nerve-guided laparoscopic total mesorectal excision for distal rectal cancer. PMID: 25331006 Ref: Expression of core clock genes in colorectal tumour cells compared with normal mucosa: a systematic review of clinical trials. PMID: 25418520 Ref: Case-control study of the PERIOD3 clock gene length polymorphism and colorectal adenoma formation. PMID: 25501848 Ref: Circadian Clock Gene CRY2 Degradation Is Involved in Chemoresistance of Colorectal Cancer. PMID: 25855785 Ref: Identification of Circadian Determinants of Cancer Chronotherapy through In Vitro Chronopharmacology and Mathematical Modeling. PMID: 26141947 Ref: OVEREXPRESSION OF BOTH CLOCK AND BMAL1 INHIBITS ENTRY TO S PHASE IN HUMAN COLON CANCER CELLS. PMID: 26370682 Ref: Circadian gene expression predicts patient response to neoadjuvant chemoradiation therapy for rectal cancer. PMID: 26617816 |
Ref: Circadian Clock in a Mouse Colon Tumor Regulates Intracellular Iron Levels to Promote Tumor Progression. PMID: 26797126 Ref: Expression of PER, CRY, and TIM genes for the pathological features of colorectal cancer patients. PMID: 27103825 Ref: Analysis of clock gene-miRNA correlation networks reveals candidate drivers in colorectal cancer. PMID: 27323779 Ref: Disruption of clock gene expression in human colorectal liver metastases. PMID: 27492458 Ref: [Preliminary investigation of intramural lateral spread distance in pull-through conformal resection of low rectal cancer]. PMID: 27680072 Ref: Aging related methylation influences the gene expression of key control genes in colorectal cancer and adenoma. PMID: 28058013 |
Ref: Case-control study of candidate gene methylation and adenomatous polyp formation. PMID: 27771773 Ref: Association between telomere length and the risk of colorectal cancer: a meta-analysis of observational studies. PMID: 28056862 Ref: Genetic variation of clock genes and cancer risk: a field synopsis and meta-analysis. PMID: 28177907 Ref: Enhancing circadian clock function in cancer cells inhibits tumor growth. PMID: 28196531 Ref: Perianal synovial sarcoma treated postoperatively with Iodine-125 brachytherapy: Technical details. PMID: 28365084 Ref: Upregulation of circadian gene 'hClock' contribution to metastasis of colorectal cancer. PMID: 28498393 Ref: [Standardized development of transanal endoscopic microsurgery]. PMID: 28836241 Ref: miR-6883 Family miRNAs Target CDK4/6 to Induce G1 Phase Cell-Cycle Arrest in Colon Cancer Cells. PMID: 29061672 Ref: Expression of circadian clock genes in human colorectal adenoma and carcinoma. PMID: 29113166 |
Ref: [A Case of Metastatic Carcinoma of Anal Fistula]. PMID: 29362337 Ref: Shiftwork-Mediated Disruptions of Circadian Rhythms and Sleep Homeostasis Cause Serious Health Problems. PMID: 29607311 Ref: Expression of clock genes cry1 and cry2 in human colorectal cancer and tumor adjacent tissues correlates with location of tumor differently. PMID: 29940771 Ref: Sex-dependent correlation between survival and expression of genes related to the circadian oscillator in patients with colorectal cancer. PMID: 29953268 Ref: The Circadian Clock Regulates Metabolic Phenotype Rewiring Via HKDC1 and Modulates Tumor Progression and Drug Response in Colorectal Cancer. PMID: 30005951 |