Primary Site >> Colorectal Cancer
Gene >> CLDN2
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Ref: Selective up-regulation of claudin-1 and claudin-2 in colorectal cancer. PMID: 17970035 |
Ref: Disturbed expression of E-cadherin, beta-catenin and tight junction proteins in colon carcinoma is unrelated to growth pattern and genetic polymorphisms. PMID: 18397460 |
Ref: Claudin expression in rectal well-differentiated endocrine neoplasms (carcinoid tumors). PMID: 19082451 Ref: Expression of tight and adherens junction proteins in ulcerative colitis associated colorectal carcinoma: upregulation of claudin-1, claudin-3, claudin-4, and beta-catenin. PMID: 19184060 Ref: Tumor volume of colon carcinoma is related to the invasive pattern but not to the expression of cell adhesion proteins. PMID: 19245593 |
Ref: Symplekin promotes tumorigenicity by up-regulating claudin-2 expression. PMID: 20133805 |
Ref: Claudin-2 expression increases tumorigenicity of colon cancer cells: role of epidermal growth factor receptor activation. PMID: 21383692 |
Ref: Hepatocyte growth factor activator inhibitor type 1 is a suppressor of intestinal tumorigenesis. PMID: 23447577 Ref: Epithelial cell adhesion molecule (EpCAM) regulates claudin dynamics and tight junctions. PMID: 23486470 Ref: Salmonella infection upregulates the leaky protein claudin-2 in intestinal epithelial cells. PMID: 23505542 Ref: Association of the epithelial-to-mesenchymal transition phenotype with responsiveness to the p21-activated kinase inhibitor, PF-3758309, in colon cancer models. PMID: 23543898 |
Ref: A mechanically-induced colon cancer cell population shows increased metastatic potential. PMID: 24884630 |
Ref: Lyn modulates Claudin-2 expression and is a therapeutic target for breast cancer liver metastasis. PMID: 25823815 Ref: Expression changes of cell-cell adhesion-related genes in colorectal tumors. PMID: 26137091 Ref: Resveratrol induces chemosensitization to 5-fluorouracil through up-regulation of intercellular junctions, Epithelial-to-mesenchymal transition and apoptosis in colorectal cancer. PMID: 26310874 |
Ref: HDAC-4 regulates claudin-2 expression in EGFR-ERK1/2 dependent manner to regulate colonic epithelial cell differentiation. PMID: 29152115 |
Ref: Transcriptomic Landscape of Treatment-Naive Ulcerative Colitis. PMID: 29040430 Ref: Treatment-related survival associations of claudin-2 expression in fibroblasts of colorectal cancer. PMID: 29134439 Ref: Pyrin Inflammasome Regulates Tight Junction Integrity to Restrict Colitis and Tumorigenesis. PMID: 29203393 Ref: Tight Junction Protein Claudin-2 Promotes Self-Renewal of Human Colorectal Cancer Stem-like Cells. PMID: 29510994 Ref: MicroRNA-488 inhibits progression of colorectal cancer via inhibition of mitogen-activated protein kinase pathway by targeting claudin-2. PMID: 30207785 |