Primary Site >> Colorectal Cancer
Gene >> CLDN1
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Ref: Involvement of claudin-1 in the beta-catenin/Tcf signaling pathway and its frequent upregulation in human colorectal cancers. PMID: 11939410 |
Ref: CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family. PMID: 12736707 |
Ref: Claudin-1 is a strong prognostic indicator in stage II colonic cancer: a tissue microarray study. PMID: 15475928 Ref: Intestinal perineuriomas: clinicopathologic definition of a new anatomic subset in a series of 10 cases. PMID: 15958849 Ref: Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer. PMID: 15965503 Ref: Claudins upregulation in human colorectal cancer. PMID: 16253248 |
Ref: Morphological and molecular alterations at the junctional complex in irradiated human colon adenocarcinoma cells, Caco-2. PMID: 17050478 |
Ref: Differential expression of genes encoding tight junction proteins in colorectal cancer: frequent dysregulation of claudin-1, -8 and -12. PMID: 17047970 Ref: Smad4 regulates claudin-1 expression in a transforming growth factor-beta-independent manner in colon cancer cells. PMID: 17308096 Ref: [Cloning of tight junction protein claudin-1 and construction of the mammalian expression vector]. PMID: 17425989 Ref: Selective up-regulation of claudin-1 and claudin-2 in colorectal cancer. PMID: 17970035 |
Ref: Reduced expression of the claudin-7 gene correlates with venous invasion and liver metastasis in colorectal cancer. PMID: 18357381 Ref: Smad7 induces hepatic metastasis in colorectal cancer. PMID: 18781153 Ref: Prostaglandin E2-EP1 and EP2 receptor signaling promotes apical junctional complex disassembly of Caco-2 human colorectal cancer cells. PMID: 19055708 |
Ref: Expression of tight and adherens junction proteins in ulcerative colitis associated colorectal carcinoma: upregulation of claudin-1, claudin-3, claudin-4, and beta-catenin. PMID: 19184060 Ref: Smad4 restoration leads to a suppression of Wnt/beta-catenin signaling activity and migration capacity in human colon carcinoma cells. PMID: 19284991 Ref: Claudin-1 protein is a major factor involved in the tumorigenesis of colorectal cancer. PMID: 19414319 |
Ref: HDAC inhibitors regulate claudin-1 expression in colon cancer cells through modulation of mRNA stability. PMID: 19881542 Ref: Expression of claudin-1, -3, -4, -5 and -7 proteins in low grade colorectal carcinoma of canines. PMID: 19924641 Ref: Increased claudin-1 protein expression contributes to tumorigenesis in ulcerative colitis-associated colorectal cancer. PMID: 20871038 Ref: Claudin 1 and Claudin 7 Gene Polymorphisms and Protein Derangement are Unrelated to the Growth Pattern and Tumor Volume of Colon Carcinoma. PMID: 23675182 |
Ref: Dysregulation of Claudin family genes in colorectal cancer in a Chinese population. PMID: 21294205 Ref: Cluster analysis of claudin-1 and -4, E-cadherin, and beta-catenin expression in colorectal cancers. PMID: 21360533 Ref: Lithium reduces tumorigenic potential in response to EGF signaling in human colorectal cancer cells. PMID: 21369697 Ref: Epithelial tight junctional changes in colorectal cancer tissues. PMID: 21479352 Ref: Prognostic importance of Claudin-1 and Claudin-4 expression in colon carcinomas. PMID: 21493012 Ref: Expression of CLDN1 in colorectal cancer: a novel marker for prognosis. PMID: 21720707 Ref: Genome-wide profiling of DNA methylation in human cancer cells. PMID: 21821115 Ref: Decreased expression of claudin-1 in rectal cancer: a factor for recurrence and poor prognosis. PMID: 21873169 Ref: Claudin-1 up-regulates the repressor ZEB-1 to inhibit E-cadherin expression in colon cancer cells. PMID: 21878201 Ref: KDM6B/JMJD3 histone demethylase is induced by vitamin D and modulates its effects in colon cancer cells. PMID: 21890490 |
Ref: Cholesteryl butyrate solid lipid nanoparticles inhibit the adhesion and migration of colon cancer cells. PMID: 22049973 Ref: Analysis of Snail-1, E-cadherin and claudin-1 expression in colorectal adenomas and carcinomas. PMID: 22408413 Ref: Increased claudin-1 protein expression in hepatic metastatic lesions of colorectal cancer. PMID: 22641667 Ref: Caudal homeobox protein Cdx-2 cooperates with Wnt pathway to regulate claudin-1 expression in colon cancer cells. PMID: 22719836 Ref: Claudin-1 expression confers resistance to anoikis in colon cancer cells in a Src-dependent manner. PMID: 22941059 Ref: [Expression and clinical significance of Claudin-1 and Claudin-4 in colorectal cancer tissues]. PMID: 23099910 |
Ref: Rab25 regulates integrin expression in polarized colonic epithelial cells. PMID: 23345591 Ref: Epithelial cell adhesion molecule (EpCAM) regulates claudin dynamics and tight junctions. PMID: 23486470 Ref: Upregulation of microRNA-155 promotes the migration and invasion of colorectal cancer cells through the regulation of claudin-1 expression. PMID: 23588589 Ref: Identification of putative immunologic targets for colon cancer prevention based on conserved gene upregulation from preinvasive to malignant lesions. PMID: 23682078 Ref: Trichostatin-A modulates claudin-1 mRNA stability through the modulation of Hu antigen R and tristetraprolin in colon cancer cells. PMID: 23880304 Ref: Low expression of claudin-1 and presence of poorly-differentiated tumor clusters correlate with poor prognosis in colorectal cancer. PMID: 23898096 Ref: Claudin-3 overexpression increases the malignant potential of colorectal cancer cells: roles of ERK1/2 and PI3K-Akt as modulators of EGFR signaling. PMID: 24069372 |
Ref: Claudin-1 regulates intestinal epithelial homeostasis through the modulation of Notch-signalling. PMID: 23766441 Ref: Polymorphisms in the CLDN1 and CLDN7 genes are related to differentiation and tumor stage in colon carcinoma. PMID: 24479816 Ref: Claudin-1 Expression Is Elevated in Colorectal Cancer Precursor Lesions Harboring the BRAF V600E Mutation. PMID: 24954356 Ref: Claudin-1 overexpression in intestinal epithelial cells enhances susceptibility to adenamatous polyposis coli-mediated colon tumorigenesis. PMID: 24997475 Ref: Loss of tight junction proteins (Claudin 1, 4, and 7) correlates with aggressive behavior in colorectal carcinoma. PMID: 25038829 |
Ref: B-Raf inhibitors induce epithelial differentiation in BRAF-mutant colorectal cancer cells. PMID: 25381152 Ref: rs17501976 polymorphism of CLDN1 gene is associated with decreased risk of colorectal cancer in a Chinese population. PMID: 25785120 Ref: Dendrosomal curcumin inhibits metastatic potential of human SW480 colon cancer cells through Down-regulation of Claudin1, Zeb1 and Hef1-1 gene expression. PMID: 25824783 Ref: Expression changes of cell-cell adhesion-related genes in colorectal tumors. PMID: 26137091 Ref: MIR517C inhibits autophagy and the epithelial-to-mesenchymal (-like) transition phenotype in human glioblastoma through KPNA2-dependent disruption of TP53 nuclear translocation. PMID: 26553592 Ref: Clinical significance of serum claudin-1 and claudin-7 levels in patients with colorectal cancer. PMID: 26807230 |
Ref: Cell-surface markers for colon adenoma and adenocarcinoma. PMID: 26894861 Ref: Complex Behavior of ALDH1A1 and IGFBP1 in Liver Metastasis from a Colorectal Cancer. PMID: 27152521 Ref: [capital IE, Cyrillicxpression of claudin-1, 3, and 4 in colorectal cancer and polyps]. PMID: 27296001 Ref: Filtered selection coupled with support vector machines generate a functionally relevant prediction model for colorectal cancer. PMID: 27330311 Ref: Claudin-1 promotes TNF-alpha-induced epithelial-mesenchymal transition and migration in colorectal adenocarcinoma cells. PMID: 27742576 Ref: Overexpressed Claudin-1 Can Be Visualized Endoscopically in Colonic Adenomas In Vivo. PMID: 27840845 Ref: [Effects of hydrogen-rich medium on lipopolysaccharide-induced intestinal epithelial barrier dysfunction of human colon carcinoma cells] PMID: 29917336 |
Ref: Prognostic and clinical significance of claudin-1 in colorectal cancer: A systemic review and meta-analysis. PMID: 28192244 Ref: [The expression of claudins in colonic neoplasms]. PMID: 28295005 Ref: Astilbin from Engelhardtia chrysolepis enhances intestinal barrier functions in Caco-2 cell monolayers. PMID: 28327343 Ref: Expression of claudin 1, claudin 4, and claudin 7 in colorectal cancer and its relation with CLDN DNA methylation patterns. PMID: 28381183 Ref: Antibody targeting of claudin-1 as a potential colorectal cancer therapy. PMID: 28659146 Ref: Antrodia camphorata inhibits metastasis and epithelial-to-mesenchymal transition via the modulation of claudin-1 and Wnt/beta-catenin signaling pathways in human colon cancer cells. PMID: 28688953 Ref: Prognostic significance of the genetic and the immunohistochemical expression of epithelial-mesenchymal-related markers in colon cancer. PMID: 28759954 |
Ref: Autophagy-mediated upregulation of cytoplasmic claudin 1 stimulates the degradation of SQSTM1/p62 under starvation. PMID: 29307823 Ref: Claudin-1 role in colon cancer: An update and a review. PMID: 29504115 Ref: Serrated epithelial colorectal polyps (hyperplastic polyps, sessile serrated adenomas) with perineurial stroma: Clinicopathological and molecular analysis of a new series. PMID: 29747061 Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). PMID: 29786110 Ref: Phytic acid improves intestinal mucosal barrier damage and reduces serum levels of proinflammatory cytokines in a 1,2-dimethylhydrazine-induced rat colorectal cancer model. PMID: 29947321 Ref: Downregulation of hepatic lipase is associated with decreased CD133 expression and clone formation in HepG2 cells. PMID: 30015857 Ref: Opposite functions of GSN and OAS2 on colorectal cancer metastasis, mediating perineural and lymphovascular invasion, respectively. PMID: 30148861 |