Primary Site >> Colorectal Cancer

Gene >> CHPT1

  • 1995
  • 1996
  • 1999
  • 2001
  • 2002
  • 2004
  • 2008
  • 2010
  • 2011
Ref: Differential stabilization of eukaryotic DNA topoisomerase I cleavable complexes by camptothecin derivatives.
PMID: 7766631
Ref: Clinical trials of irinotecan hydrochloride (CPT, campto injection, topotecin injection) in Japan.
PMID: 8993523
Ref: Homocamptothecin, an E-ring modified camptothecin with enhanced lactone stability, retains topoisomerase I-targeted activity and antitumor properties.
PMID: 10383158
Ref: A novel B-ring modified homocamptothecin, 12-Cl-hCPT, showing antiproliferative and topoisomerase I inhibitory activities superior to SN-38.
PMID: 11762642
Ref: Ceramide involvement in homocamptothecin- and camptothecin-induced cytotoxicity and apoptosis in colon HT29 cells.
PMID: 11894136
Ref: Cytotoxic effect of different camptothecin formulations on human colon carcinoma in vitro.
PMID: 15457131
Ref: [Three cases with liver metastasis from gastric or colon cancer successfully treated with S-1 combined with CPT- 11].
PMID: 18799916
Ref: Moxifloxacin increases anti-tumor and anti-angiogenic activity of irinotecan in human xenograft tumors.
PMID: 20025849
Ref: RECQL5 is an important determinant for camptothecin tolerance in human colorectal cancer cells.
PMID: 21210765
Ref: Surface-modified silica nanoparticles for tumor-targeted delivery of camptothecin and its biological evaluation.
PMID: 21756949