Primary Site >> Colorectal Cancer

Gene >> CHKA

  • 1998
  • 1999
  • 2003
  • 2006
  • 2016
  • 2018
Ref: [Molecular effects of vitamin D on cell cycle and oncogenesis].
PMID: 9691832
Ref: RNA synthesis block by 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) triggers p53-dependent apoptosis in human colon carcinoma cells.
PMID: 10523857
Ref: [Stat3 signal transduction pathway orchestrates G1 to S cell cycle transition in colon cancer cells].
PMID: 12920809
Ref: Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway.
PMID: 16574813
Ref: Overexpression of CHKA contributes to tumor progression and metastasis and predicts poor prognosis in colorectal carcinoma.
PMID: 27556502
Ref: Radiosensitization by irinotecan is attributed to G2/M phase arrest, followed by enhanced apoptosis, probably through the ATM/Chk/Cdc25C/Cdc2 pathway in p53-mutant colorectal cancer cells.
PMID: 30085332