Primary Site >> Esophagus Cancer

Gene >> CHEK2

  • 2006
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  • 2016
Ref: [Effect on retardation of G2/M phase in esophageal carcinoma cells transfected with CHK1 and CHK2 shRNA after irradiation].
PMID: 17236549
Ref: [Effects of RNA interference on CHK1 and CHK2 expression and G2/M arrest in esophageal carcinoma cell line TE13 after irradiation].
PMID: 17298739
Ref: Variant allele of CHEK2 is associated with a decreased risk of esophageal cancer lymph node metastasis in a Chinese population.
PMID: 22201027
Ref: Overexpression of Cdc25C predicts response to radiotherapy and survival in esophageal squamous cell carcinoma patients treated with radiotherapy followed by surgery.
PMID: 23470146
Ref: Genetic variants in DNA repair pathway genes and risk of esophageal squamous cell carcinoma and gastric adenocarcinoma in a Chinese population.
PMID: 23504502
Ref: Sterigmatocystin induces G1 arrest in primary human esophageal epithelial cells but induces G2 arrest in immortalized cells: key mechanistic differences in these two models.
PMID: 25294323
Ref: Combination of SNX-2112 with 5-FU exhibits antagonistic effect in esophageal cancer cells.
PMID: 25333998
Ref: Jaridonin-induced G2/M phase arrest in human esophageal cancer cells is caused by reactive oxygen species-dependent Cdc2-tyr15 phosphorylation via ATM-Chk1/2-Cdc25C pathway.
PMID: 25450480
Ref: Polymorphisms in checkpoint kinase 2 may contribute to lymph node metastasis from esophageal cancer.
PMID: 26550343
Ref: Genetic variants at 6p21, 10q23, 16q21 and 22q12 are associated with esophageal cancer risk in a Chinese Han population.
PMID: 26770579
Ref: Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer.
PMID: 26857264
Ref: The medicinal fungus Antrodia cinnamomea regulates DNA repair and enhances the radiosensitivity of human esophageal cancer cells.
PMID: 27826196