Primary Site >> Colorectal Cancer

Gene >> CFL1

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Ref: MRNA expression of genes altered by 5-azacytidine treatment in cancer cell lines is associated with clinicopathological parameters of human cancers.
PMID: 11768609
Ref: Proteome analysis reveals novel proteins associated with proliferation and differentiation of the colorectal cancer cell line Caco-2.
PMID: 12922171
Ref: Upregulation and dephosphorylation of cofilin: modulation by CD44 variant isoform in human colon cancer cells.
PMID: 16229833
Ref: Differential involvement of destrin and cofilin-1 in the control of invasive properties of Isreco1 human colon cancer cells.
PMID: 17583572
Ref: CD44 regulates cell migration in human colon cancer cells via Lyn kinase and AKT phosphorylation.
PMID: 17599831
Ref: Effects of ROCK inhibitor, Y-27632, on adhesion and mobility in esophageal squamous cell cancer cells.
PMID: 19649725
Ref: Oncogenic K-Ras turns death receptors into metastasis-promoting receptors in human and mouse colorectal cancer cells.
PMID: 20188103
Ref: Coagulation Factor Xa inhibits cancer cell migration via LIMK1-mediated cofilin inactivation.
PMID: 20347121
Ref: Comparative proteomic analysis of irinotecan-sensitive colorectal carcinoma cell line and its chemoresistant counterpart.
PMID: 21637159
Ref: Inhibition of Rho-associated coiled-coil containing protein kinase enhances the activation of epidermal growth factor receptor in pancreatic cancer cells.
PMID: 21722395
Ref: The death receptor CD95 activates the cofilin pathway to stimulate tumour cell invasion.
PMID: 21760611
Ref: Identification of phosphorylated serine-15 and -82 residues of HSPB1 in 5-fluorouracil-resistant colorectal cancer cells by proteomics.
PMID: 21989268
Ref: DADS downregulates the Rac1-ROCK1/PAK1-LIMK1-ADF/cofilin signaling pathway, inhibiting cell migration and invasion.
PMID: 23233092
Ref: Knockdown of PAK4 or PAK1 inhibits the proliferation of mutant KRAS colon cancer cells independently of RAF/MEK/ERK and PI3K/AKT signaling.
PMID: 23233484
Ref: Biological characterization of the antiproliferative potential of Co(II) and Sn(IV) coordination compounds in human cancer cell lines: a comparative proteomic approach.
PMID: 23800656
Ref: EZH2 regulates cofilin activity and colon cancer cell migration by targeting ITGA2 gene.
PMID: 25549357
Ref: MicroRNA-429 inhibits the migration and invasion of colon cancer cells by targeting PAK6/cofilin signaling.
PMID: 26058485
Ref: MIF, secreted by human hepatic sinusoidal endothelial cells, promotes chemotaxis and outgrowth of colorectal cancer in liver prometastasis.
PMID: 26087187
Ref: Neuron navigator 2 overexpression indicates poor prognosis of colorectal cancer and promotes invasion through the SSH1L/cofilin-1 pathway.
PMID: 26452645
Ref: MiR-145 inhibits human colorectal cancer cell migration and invasion via PAK4-dependent pathway.
PMID: 28440035
Ref: Prion Protein Family Contributes to Tumorigenesis via Multiple Pathways.
PMID: 29052140
Ref: Induced cortical tension restores functional junctions in adhesion-defective carcinoma cells.
PMID: 29184140
Ref: YAP Inhibits the Apoptosis and Migration of Human Rectal Cancer Cells via Suppression of JNK-Drp1-Mitochondrial Fission-HtrA2/Omi Pathways.
PMID: 29241219
Ref: LIMK/cofilin pathway and Slingshot are implicated in human colorectal cancer progression and chemoresistance.
PMID: 29352327
Ref: PRP4 kinase induces actin rearrangement and epithelial-mesenchymal transition through modulation of the actin-binding protein cofilin.
PMID: 29787735
Ref: Cofilin-1 signaling mediates epithelial-mesenchymal transition by promoting actin cytoskeleton reorganization and cell-cell adhesion regulation in colorectal cancer cells.
PMID: 30296500