Primary Site >> Colorectal Cancer
Gene >> CEACAM6
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Ref: The zinc glycinate marker in human colon carcinoma. PMID: 1255760 |
Ref: A putatively new antigen (CSAp) associated with gastrointestinal and ovarian neoplasia. PMID: 407152 |
Ref: Isolation of CEA-like material from urinary bladder carcinoma. PMID: 217136 |
Ref: Immunologic and biochemical studies on the carcinoembryonic antigen-like substance in human neuroblastoma. PMID: 86182 |
Ref: Purification and characterization of a 50,000 mol. wt glycoprotein antigen, and localization of determinants involved in cross-reactivity with carcinoembryonic antigen. PMID: 6191208 Ref: Granular cell myoblastoma: an immunoperoxidase study using a variety of antisera to human carcinoembryonic antigen. PMID: 6301969 |
Ref: Monoclonal antibodies identify a CEA crossreacting antigen of 95 kD (NCA-95) distinct in antigenicity and tissue distribution from the previously described NCA of 55 kD. PMID: 6724739 |
Ref: Association of the Y hapten with glycoproteins, glycolipids and carcinoembryonic antigen in colorectal carcinoma. PMID: 3768863 |
Ref: Mapping of monoclonal antibody-defined epitopes associated with carcinoembryonic antigen, CEA. PMID: 2439201 |
Ref: Differential expression of carcinoembryonic antigen and nonspecific crossreacting antigen genes in human colon adenocarcinomas and normal colon mucosa. PMID: 3133333 Ref: Protein analysis of NCA-50 shows identity to NCA cDNA deduced sequences and indicates posttranslational modifications. PMID: 3390172 |
Ref: Serologic mapping and biochemical characterization of the carcinoembryonic antigen epitopes using fourteen distinct monoclonal antibodies. PMID: 2474516 Ref: Conformational epitopes specific to carcinoembryonic antigen defined by monoclonal antibodies raised against colon cancer xenografts. PMID: 2475724 |
Ref: Monoclonal antibodies to carcino-embryonic antigen. PMID: 1701159 Ref: Tumor specificity of monoclonal antibodies to carcinoembryonic antigen. Immunohistochemical analysis. PMID: 2408131 |
Ref: The high lysability by LAK cells of colon-carcinoma cells resistant to doxorubicin is associated with a high expression of ICAM-1, LFA-3, NCA and a less-differentiated phenotype. PMID: 1706327 Ref: Transduction and expression of the human carcinoembryonic antigen gene in a murine colon carcinoma cell line. PMID: 1712245 Ref: Biosynthesis of carcinoembryonic antigen (CEA) gene family members expressed in human tumor cell lines: evidence for cleavage of the glycosyl phosphatidyl inositol (GPI) anchor by GPI-PLC and GPI-PLD. PMID: 1815506 Ref: Production and characterization of monoclonal antibodies against carcinoembryonic antigen (CEA). PMID: 1824544 |
Ref: Reactivities of an anti-CEA peptide monoclonal antibody. PMID: 1374782 Ref: CEA and NCA expressed by colon carcinoma cells affect their interaction with and lysability by activated lymphocytes. PMID: 1431336 |
Ref: Antiserum to carcinoembryonic antigen recognizes a phosphotyrosine-containing protein in human colon cancer cell lines. PMID: 7680008 Ref: Characterization of second-generation monoclonal antibodies against carcinoembryonic antigen. PMID: 7683969 Ref: Adhesion to carcinoembryonic antigen by human colorectal carcinoma cells involves at least two epitopes. PMID: 7690347 Ref: Determination of the specificities of monoclonal antibodies recognizing members of the CEA family using a panel of transfectants. PMID: 7690348 Ref: Expression of carcinoembryonic antigen (CEA) and nonspecific crossreacting antigen (NCA) in gastrointestinal cancer; the correlation with degree of differentiation. PMID: 8318403 Ref: Differential regulation of carcinoembryonic antigen and biliary glycoprotein by gamma-interferon. PMID: 8453631 |
Ref: Nonspecific cross-reacting antigen 50/90 is elevated in patients with breast, lung, and colon cancer. PMID: 8118811 Ref: A putative CEA moiety is shared by the cotton-top tamarin (Saguinus oedipus) and humans. PMID: 8162564 |
Ref: CD66b, CD66c and carcinoembryonic antigen (CEA) are independently regulated markers in sera of tumor patients. PMID: 7591230 Ref: Carbohydrate structures of a normal counterpart of the carcinoembryonic antigen produced by colon epithelial cells of normal adults. PMID: 7772858 |
Ref: Antigen heterogeneity in advanced colorectal and breast cancer. PMID: 21541535 Ref: Cell mediated cytotoxicity of human colon carcinoma cells by a monoclonal antibody (R4) recognizing the carcinoembryonic antigen (CEA) and CEA-related molecules. PMID: 21544473 |
Ref: A colonic tissue architecture assay applied to human colon carcinoma cells. PMID: 9028835 Ref: Decreased expression of biliary glycoprotein in hepatocellular carcinomas. PMID: 9036863 Ref: Cis-acting elements required for expression of the nonspecific cross-reacting antigen gene in colorectal carcinoma. PMID: 9041239 Ref: Several carcinoembryonic antigens (CD66) serve as receptors for gonococcal opacity proteins. PMID: 9151893 |
Ref: Transcriptional regulation of the non-specific cross-reacting antigen gene, a member of the carcinoembryonic antigen gene family up-regulated in colorectal carcinomas. PMID: 9654079 Ref: Adhesion of colorectal carcinoma cells to the endothelium is mediated by cytokines from CEA stimulated Kupffer cells. PMID: 10211983 |
Ref: Deregulated expression of the human tumor marker CEA and CEA family member CEACAM6 disrupts tissue architecture and blocks colonocyte differentiation. PMID: 11896570 Ref: Protein epitopes in carcinoembryonic antigen. Report of the ISOBM TD8 workshop. PMID: 12499780 |
Ref: Expression of CEACAM6 in resectable colorectal cancer: a factor of independent prognostic significance. PMID: 14512395 Ref: Interferon-gamma tempers the expression of carcinoembryonic antigen family molecules in human colon cells: a possible role in innate mucosal defence. PMID: 14636419 |
Ref: DNA microarray analysis of vitamin D-induced gene expression in a human colon carcinoma cell line. PMID: 14996990 Ref: Fully human IgG and IgM antibodies directed against the carcinoembryonic antigen (CEA) Gold 4 epitope and designed for radioimmunotherapy (RIT) of colorectal cancers. PMID: 15488142 |
Ref: Elevated expression and potential roles of human Sp5, a member of Sp transcription factor family, in human cancers. PMID: 16380080 Ref: Multiplex detection of surface molecules on colorectal cancers. PMID: 16485257 Ref: Increased colon tumor susceptibility in azoxymethane treated CEABAC transgenic mice. PMID: 16632476 Ref: Biomarker selection for detection of occult tumour cells in lymph nodes of colorectal cancer patients using real-time quantitative RT-PCR. PMID: 16755296 |
Ref: Expression patterns of CEACAM5 and CEACAM6 in primary and metastatic cancers. PMID: 17201906 Ref: Low dietary calcium levels modulate mucosal caspase expression and increase disease activity in mice with dextran sulfate sodium induced colitis. PMID: 17951488 Ref: Colorectal hyperplasia and dysplasia due to human carcinoembryonic antigen (CEA) family member expression in transgenic mice. PMID: 18159236 |
Ref: Contribution of intestinal epithelial cells to innate immunity of the human gut--studies on polarized monolayers of colon carcinoma cells. PMID: 19170965 |
Ref: Comparison of membrane fraction proteomic profiles of normal and cancerous human colorectal tissues with gel-assisted digestion and iTRAQ labeling mass spectrometry. PMID: 20546304 |
Ref: [Human carcinoembryonic antigen family proteins, structure and function]. PMID: 22922152 |
Ref: Overexpression and clinical significance of carcinoembryonic antigen-related cell adhesion molecule 6 in colorectal cancer. PMID: 22975528 Ref: CD66c is a novel marker for colorectal cancer stem cell isolation, and its silencing halts tumor growth in vivo. PMID: 23027178 Ref: Cytometric profiling of CD133+ cells in human colon carcinoma cell lines identifies a common core phenotype and cell type-specific mosaics. PMID: 23709346 Ref: Prioritization of cancer marker candidates based on the immunohistochemistry staining images deposited in the human protein atlas. PMID: 24303032 |
Ref: A novel llama antibody targeting Fn14 exhibits anti-metastatic activity in vivo. PMID: 24135629 |
Ref: Recombinant Salmonella-based CEACAM6 and 4-1BBL vaccine enhances T-cell immunity and inhibits the development of colorectal cancer in rats: In vivo effects of vaccine containing 4-1BBL and CEACAM6. PMID: 25872647 Ref: Interleukin-6 trans-signaling increases the expression of carcinoembryonic antigen-related cell adhesion molecules 5 and 6 in colorectal cancer cells. PMID: 26673628 Ref: Emerging Role and Targeting of Carcinoembryonic Antigen-related Cell Adhesion Molecule 6 (CEACAM6) in Human Malignancies. PMID: 27595061 |
Ref: Systematic large-scale meta-analysis identifies a panel of two mRNAs as blood biomarkers for colorectal cancer detection. PMID: 26993598 Ref: Major Protein of Carcinoembryonic Antigen Gene Family - CD66c, A Novel Marker in Colon Carcinoma. PMID: 27042567 Ref: Generation of a monoclonal antibody recognizing the CEACAM glycan structure and inhibiting adhesion using cancer tissue-originated spheroid as an antigen. PMID: 27098764 Ref: FOXP3 and CEACAM6 expression and T cell infiltration in the occurrence and development of colon cancer. PMID: 27284373 |
Ref: T cell immunity induced by a bivalent Salmonella-based CEACAM6 and 4-1BBL vaccines in a rat colorectal cancer model. PMID: 28521477 Ref: AA-NAT, MT1 and MT2 Correlates with Cancer Stem-Like Cell Markers in Colorectal Cancer: Study of the Influence of Stage and p53 Status of Tumors. PMID: 28604612 Ref: EphA2 signaling is impacted by carcinoembryonic antigen cell adhesion molecule 1-L expression in colorectal cancer liver metastasis in a cell context-dependent manner. PMID: 29262644 |
Ref: LGALS4, CEACAM6, TSPAN8, and COL1A2: Blood Markers for Colorectal Cancer-Validation in a Cohort of Subjects With Positive Fecal Immunochemical Test Result. PMID: 29352642 |