Primary Site >> Colorectal Cancer
Gene >> CEACAM5
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Ref: Patterns of serial CEA assays and their clinical use in management of colorectal cancer. PMID: 994514 |
Ref: Ultrastructural localization of carcinoembryonic antigen in normal intestine and colon cancer: abnormal distribution of CEA on the surfaces of colon cancer cells. PMID: 7042066 |
Ref: [Monoclonal antibodies to digestive-tract cancer]. PMID: 6870303 |
Ref: [CA 12-5 in cancer of the digestive tract. A comparison with CA 19-9 and CEA in cancer of the pancreas and colon]. PMID: 6595110 |
Ref: [Clinical study on serum 5'-nucleotide phosphodiesterase isoenzyme-V as a predictor of liver metastases in patients with gastric and colorectal cancers]. PMID: 3018474 Ref: Characterization of a new monoclonal antibody to a cell surface antigen on colorectal cancer and fetal gut tissues. PMID: 3510703 |
Ref: Carcinoembryonic antigen family: expression in a mouse L-cell transfectant and characterization of a partial cDNA in bacteriophage lambda gt11. PMID: 2955415 Ref: [Radioimmunoscintigraphy with monoclonal antibodies]. PMID: 3500011 Ref: Immunoscintigraphy of colorectal carcinoma with F (ab')2 fragments of anti-CEA monoclonal antibody. PMID: 3568032 |
Ref: Tumor imaging of colo-rectal carcinoma with an anti-CEA monoclonal antibody. PMID: 3162449 Ref: Tumour localization using monoclonal antibodies. II. Biodistribution of A5B7/111indium chelates. PMID: 3209298 Ref: Radiolocalisation of an anti-CEA monoclonal antibody (FO23C5) and its fragments in a colon carcinoma xenograft model. PMID: 3235854 |
Ref: [Two cases of gastrointestinal cancers with major responses to sequential methotrexate 5-FU plus 5'-DFUR]. PMID: 2525005 Ref: Promotion of differentiation in human colon carcinoma cells by vasoactive intestinal polypeptide. PMID: 2544928 Ref: Carcinoembryonic antigen, a human tumor marker, functions as an intercellular adhesion molecule. PMID: 2702691 |
Ref: Epithelial markers in pancreatic carcinoma: immunoperoxidase localisation of DD9, CEA, EMA and CAM 5.2. PMID: 1696288 Ref: Carcinoembryonic antigen functions as an accessory adhesion molecule mediating colon epithelial cell-collagen interactions. PMID: 2304917 |
Ref: Specific adhesion of carcinoembryonic antigen-bearing colorectal cancer cells to immobilized carcinoembryonic antigen. PMID: 1657369 Ref: A new radioimmunoassay detecting early stages of colon cancer: a comparison with CEA, AFP, and Ca 19-9. PMID: 1724634 Ref: The value of radioimmunoguided surgery in first and second look laparotomy for colorectal cancer. PMID: 1999127 Ref: Immunoscintigraphy of colorectal carcinoma with an anti-CEA monoclonal antibody: a critical review. PMID: 2010305 |
Ref: Expression of the cell surface antigen detected by the monoclonal antibody A7 in pancreatic carcinoma cell lines. PMID: 1327320 Ref: Pilot, multicenter and prospective trials with an anti-CEA antibody. PMID: 1431344 Ref: Anti-CEA and other antibodies in the study of gastrointestinal tumors. PMID: 1431346 Ref: Interleukin-6 increases carcinoembryonic antigen and histocompatibility leukocyte antigen expression on the surface of human colorectal carcinoma cells. PMID: 1477074 Ref: Specificity and affinity of monoclonal antibodies against carcinoembryonic antigen. PMID: 1559235 |
Ref: Colon carcinoma cells blocked in polarization exhibit increased expression of carcinoembryonic antigen. PMID: 8241027 Ref: Transcription of carcinoembryonic antigen in normal colon and colon carcinoma. In situ hybridization study and implication for a new in vivo functional model. PMID: 8317550 Ref: [Radioimmunodetection of colorectal cancer, using anti-CEA monoclonal antibody CEA102: experience of 20 cases]. PMID: 8464409 |
Ref: Alpha interferon, leucovorin, and 5-fluorouracil (ALF) in advanced cancer: results of a dose-finding study and evidence of activity in non-small cell lung cancer. PMID: 8032955 Ref: A new serum tumor marker, CAM 123-6, highly specific to pulmonary adenocarcinoma. PMID: 8144402 Ref: A putative CEA moiety is shared by the cotton-top tamarin (Saguinus oedipus) and humans. PMID: 8162564 Ref: [Treatment of advanced colorectal cancer with long-term continuous infusion of 5-fluorouracil]. PMID: 8291915 |
Ref: CD66b, CD66c and carcinoembryonic antigen (CEA) are independently regulated markers in sera of tumor patients. PMID: 7591230 Ref: The effect of transfection of the CEA gene on the metastatic behavior of the human colorectal cancer cell line MIP-101. PMID: 7757961 Ref: Susceptibility of colorectal-carcinoma cells to natural-killer-mediated lysis: relationship to CEA expression and degree of differentiation. PMID: 7790122 Ref: Increased expression of sialyl Lewis A and sialyl Lewis X in liver metastases of human colorectal carcinoma. PMID: 8621274 |
Ref: Serum carcinoembryonic antigen levels and proliferating cell nuclear antigen labeling index for patients with colorectal carcinoma. Correlation with tumor progression and survival. PMID: 8608572 Ref: Intraoperative radioimmunolocalization of an anti-CEA MAb F(Ab')2 (FO23C5) in CEA serum-negative colorectal cancer patients. PMID: 8687145 Ref: Cancer cell morphology at the invasive front and expression of cell adhesion-related carbohydrate in the primary lesion of patients with colorectal carcinoma with liver metastasis. PMID: 8826938 Ref: 5-Fluorouracil continuous infusion in metastatic colorectal cancer. PMID: 8924021 Ref: Drug-induced changes of carcinoembryonic antigen expression in human cancer cells: effect of 5-fluorouracil. PMID: 8968385 |
Ref: Neural cell adhesion molecule (N-CAM) in gastrointestinal neoplasias. PMID: 9137477 Ref: Cytokeratins, CEA, and mucin histochemistry in the diagnosis and characterization of extramammary Paget's disease. PMID: 9208972 |
Ref: [A case of hepatic metastasis of rectal cancer with familial adenomatous polyposis treated by transarterial administration of low-dose leucovorin and 5-FU]. PMID: 9492838 Ref: Use of Carcinoembryonic Antigen Gene Promoter in Colorectal Carcinoma-specific Suicidal Gene Therapy. PMID: 12174289 |
Ref: Establishment of a human colon cancer cell line (PMF-ko14) displaying highly metastatic activity. PMID: 10853016 Ref: Natural T-cell response against MHC class I epitopes of epithelial cell adhesion molecule, her-2/neu, and carcinoembryonic antigen in patients with colorectal cancer. PMID: 10987297 |
Ref: Protective immunity against human carcinoembryonic antigen (CEA) induced by an oral DNA vaccine in CEA-transgenic mice. PMID: 11300483 Ref: Mutations in the carcinoembryonic antigen gene in colorectal cancer patients: implications on liver metastasis. PMID: 11306451 Ref: Bispecific antibody targeting of doxorubicin to carcinoembryonic antigen-expressing colon cancer cell lines in vitro and in vivo. PMID: 11351306 Ref: The infection of human dendritic cells with recombinant avipox vectors expressing a costimulatory molecule transgene (CD80) to enhance the activation of antigen-specific cytolytic T cells. PMID: 11606396 Ref: Serum levels of E-selectin, ICAM-1 and VCAM-1 in colorectal cancer patients: correlations with clinicopathological features, patient survival and tumour surgery. PMID: 11720833 |
Ref: Expression and purification of recombinant immunotoxin--a fusion protein stabilizes a single-chain Fv (scFv) in denaturing condition. PMID: 12509988 Ref: Signal sequence deletion and fusion to tetanus toxoid epitope augment antitumor immune responses to a human carcinoembryonic antigen (CEA) plasmid DNA vaccine in a murine test system. PMID: 12719706 Ref: Hematopoietic growth factors in colorectal cancer patients. PMID: 12812262 Ref: The tumorigenic potential of human CX-1 colon adenocarcinoma cells depends on carcinoembryonic antigen (CEACAM5) expression. PMID: 12813580 Ref: Human tumor-derived heat shock protein 96 mediates in vitro activation and in vivo expansion of melanoma- and colon carcinoma-specific T cells. PMID: 14500642 Ref: Carcinoembryonic antigen-producing cell-specific oncolytic adenovirus, OV798, for colorectal cancer therapy. PMID: 14578465 Ref: Interferon-gamma tempers the expression of carcinoembryonic antigen family molecules in human colon cells: a possible role in innate mucosal defence. PMID: 14636419 Ref: [A case of multiple hepatic metastases from colorectal cancer effectively treated by arterial infusion therapy with Leucovorin/5-FU]. PMID: 14650973 |
Ref: Detection of occult tumour cells in lymph nodes of colorectal cancer patients using real-time quantitative RT-PCR for CEA and CK20 mRNAS. PMID: 15185350 Ref: [A case of advanced descending colon cancer with peritoneal dissemination responding to weekly high-dose l-leucovorin/5-fluorouracil combination therapy]. PMID: 15272595 |
Ref: Survival after surgical treatment of cancer of the rectum. PMID: 15309541 Ref: Transcriptome analysis of a human colorectal cancer cell line shows molecular targets of insulin-like growth factor-binding protein-4 overexpression. PMID: 15455346 Ref: Carcinoembryonic antigen antibody inhibits lung metastasis and augments chemotherapy in a human colonic carcinoma xenograft. PMID: 15592930 Ref: Immunobead multiplex RT-PCR detection of carcinoembryonic genes expressing cells in the blood of colorectal cancer patients. PMID: 15843204 Ref: Forced expression of deltaN-TCF-1B in colon cancer derived cell lines is accompanied by the induction of CEACAM5/6 and mesothelin. PMID: 15890249 Ref: Dendritic cells recognize tumor-specific glycosylation of carcinoembryonic antigen on colorectal cancer cells through dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin. PMID: 15994972 Ref: Markers of cellular adhesion in diagnosis and therapy control of colorectal carcinoma. PMID: 16033066 Ref: Capecitabine as third line therapy in patients with advanced colorectal cancer. PMID: 16076695 |
Ref: Phase III trial of 5-fluorouracil and leucovorin plus either 3H1 anti-idiotype monoclonal antibody or placebo in patients with advanced colorectal cancer. PMID: 16311275 Ref: Selection, affinity maturation, and characterization of a human scFv antibody against CEA protein. PMID: 16504122 Ref: Predictors of recurrence in patients with T2 and early T3, N0 adenocarcinoma of the rectum treated by surgery alone. PMID: 16943525 |
Ref: Pretreatment serum levels of hematopoietic cytokines in patients with colorectal adenomas and cancer. PMID: 16520929 Ref: Expression patterns of CEACAM5 and CEACAM6 in primary and metastatic cancers. PMID: 17201906 Ref: Clinical factors in prediction of prognosis after anterior resection with total mesorectal excision for carcinoma of the rectum. PMID: 17203190 Ref: Immunogenicity of the carcinoembryonic antigen derived peptide 694 in HLA-A2 healthy donors and colorectal carcinoma patients. PMID: 17447064 Ref: Carcinoembryonic antigen inhibits anoikis in colorectal carcinoma cells by interfering with TRAIL-R2 (DR5) signaling. PMID: 17510406 Ref: Hypoxia upregulates carcinoembryonic antigen expression in cancer cells. PMID: 17657737 Ref: Report of an autopsy case of colon cancer with amyotrophic lateral sclerosis. PMID: 17827908 Ref: Vaccination of metastatic colorectal cancer patients with matured dendritic cells loaded with multiple major histocompatibility complex class I peptides. PMID: 17893568 |
Ref: The CEACAM1-mediated apoptosis pathway is activated by CEA and triggers dual cleavage of CEACAM1. PMID: 18278069 Ref: [5-FU/LV therapy for a rectal cancer patient undergoing continuous hemodialysis with multiple hepatic metastases--a case report]. PMID: 18633266 Ref: Overexpression and elevated plasma level of tumor-associated antigen 90K/Mac-2 binding protein in colorectal carcinoma. PMID: 21136809 |
Ref: Contribution of intestinal epithelial cells to innate immunity of the human gut--studies on polarized monolayers of colon carcinoma cells. PMID: 19170965 Ref: Potent control of tumor growth by CEA/CD3-bispecific single-chain antibody constructs that are not competitively inhibited by soluble CEA. PMID: 19342971 Ref: [Study on radiation sensitivity of colorectal cancer cells using gene expression profile]. PMID: 19598022 Ref: Humanised IgG1 antibody variants targeting membrane-bound carcinoembryonic antigen by antibody-dependent cellular cytotoxicity and phagocytosis. PMID: 19904275 |
Ref: Growth and invasion of sporadic colorectal adenocarcinomas in terms of genetic change. PMID: 20191032 Ref: Expansion of CD133(+) colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery. PMID: 20332776 Ref: Clinical significance of preoperative serum vascular endothelial growth factor, interleukin-6, and C-reactive protein level in colorectal cancer. PMID: 20465852 Ref: Comparison of membrane fraction proteomic profiles of normal and cancerous human colorectal tissues with gel-assisted digestion and iTRAQ labeling mass spectrometry. PMID: 20546304 Ref: In vitro analysis and in vivo tumor targeting of a humanized, grafted nanobody in mice using pinhole SPECT/micro-CT. PMID: 20554727 Ref: Identification by a Digital Gene Expression Displayer (DGED) and test by RT-PCR analysis of new mRNA candidate markers for colorectal cancer in peripheral blood. PMID: 20596680 Ref: IGFBP-rP1, a potential molecule associated with colon cancer differentiation. PMID: 20977730 Ref: Surveillance with serial serum carcinoembryonic levels detect colorectal cancer recurrences in patients who are initial nonsecretors. PMID: 21105619 |
Ref: Plasma TIMP-1 and CEA in detection of primary colorectal cancer: a prospective, population based study of 4509 high-risk individuals. PMID: 20799911 Ref: Predictive factors of tumor response after neoadjuvant chemoradiation for locally advanced rectal cancer. PMID: 21093174 Ref: Parameters of biological activity in colorectal cancer. PMID: 21273626 Ref: Clinicopathological and molecular characterization of colorectal micropapillary carcinoma. PMID: 21336262 Ref: Phylogenetic discordance of human and canine carcinoembryonic antigen (CEA, CEACAM) families, but striking identity of the CEA receptors will impact comparative oncology studies. PMID: 21436956 Ref: Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) recognizes a novel ligand, Mac-2-binding protein, characteristically expressed on human colorectal carcinomas. PMID: 21515679 Ref: [Development and verification of CEA positive CT26 colon cancer cell line]. PMID: 21614692 Ref: A novel anti-CEACAM5 monoclonal antibody, CC4, suppresses colorectal tumor growth and enhances NK cells-mediated tumor immunity. PMID: 21731662 |
Ref: The prognostic significant of percentage drop in serum CEA post curative resection for colon cancer. PMID: 21094039 Ref: Differential glycosylation of MUC1 and CEACAM5 between normal mucosa and tumour tissue of colon cancer patients. PMID: 21823122 Ref: Prognostic value of preoperative carcinoembryonic antigen level in colorectal cancer in Tunisia. PMID: 22311447 Ref: Expression of the phosphorylated MEK5 protein is associated with TNM staging of colorectal cancer. PMID: 22458985 Ref: Lymph node tissue kallikrein-related peptidase 6 mRNA: a progression marker for colorectal cancer. PMID: 22699826 Ref: Quantitative immuno-SPECT monitoring of pretargeted radioimmunotherapy with a bispecific antibody in an intraperitoneal nude mouse model of human colon cancer. PMID: 23081995 Ref: Prognostic and predictive value of circulating tumor cell analysis in colorectal cancer patients. PMID: 23146106 |
Ref: Elevated CEA levels and low distance of the tumor from the anal verge are predictors of incomplete response to chemoradiation in patients with rectal cancer. PMID: 23010737 Ref: Preoperative elevation of carcinoembryonic antigen predicts poor tumor response and frequent distant recurrence for patients with rectal cancer who receive preoperative chemoradiotherapy and total mesorectal excision: a multi-institutional analysis in an PMID: 23208008 Ref: Celecoxib downregulates CD133 expression through inhibition of the Wnt signaling pathway in colon cancer cells. PMID: 23245395 Ref: Novel adenoviral vector induces T-cell responses despite anti-adenoviral neutralizing antibodies in colorectal cancer patients. PMID: 23624851 Ref: Detection of resectable recurrences in colorectal cancer patients with 2-[18F]fluoro-2-deoxy-D-glucose-positron emission tomography/computed tomography. PMID: 23713869 Ref: Clinical applications of gene expression in colorectal cancer. PMID: 23730510 Ref: Development of an imaging-guided CEA-pretargeted radionuclide treatment of advanced colorectal cancer: first clinical results. PMID: 23860529 Ref: Novel protein isoforms of carcinoembryonic antigen are secreted from pancreatic, gastric and colorectal cancer cells. PMID: 24070190 Ref: Soluble carcinoembryonic antigen activates endothelial cells and tumor angiogenesis. PMID: 24121495 Ref: [Cytosine deaminase and thymidine kinase double suicide gene system driven by carcinoembryonic antigen promoter for the treatment of colorectal carcinoma xenograft in nude mice]. PMID: 24169337 Ref: The relation between pathological complete response and clinical outcome in patients with rectal cancer. PMID: 24298571 Ref: Prioritization of cancer marker candidates based on the immunohistochemistry staining images deposited in the human protein atlas. PMID: 24303032 |
Ref: Knockdown of MMP-7 inhibits cell proliferation and enhances sensitivity to 5-Fluorouracil and X-ray irradiation in colon cancer cells. PMID: 23086188 Ref: Serpin B5 is a CEA-interacting biomarker for colorectal cancer. PMID: 24114705 Ref: Investigation of cell free BIRC5 mRNA as a serum diagnostic and prognostic biomarker for colorectal cancer. PMID: 24338523 Ref: Blood eosinophil and platelet levels, proteomics patterns of trail and CXCL8 correlated with survival in bevacizumab treated metastatic colon cancers. PMID: 24660552 Ref: Carcinoembryonic antigen promotes colorectal cancer progression by targeting adherens junction complexes. PMID: 24726916 |
Ref: Improving the therapeutic index in cancer therapy by using antibody-drug conjugates designed with a moderately cytotoxic drug. PMID: 25402018 Ref: Strengthened tumor antigen immune recognition by inclusion of a recombinant Eimeria antigen in therapeutic cancer vaccination. PMID: 25655760 Ref: Utility of postoperative CEA for surveillance of recurrence after resection of primary colorectal cancer. PMID: 25771102 Ref: Cell Free DNA of Tumor Origin Induces a 'Metastatic' Expression Profile in HT-29 Cancer Cell Line. PMID: 26133168 Ref: Elevated expression of ECT2 predicts unfavorable prognosis in patients with colorectal cancer. PMID: 26211594 Ref: Increased expression of Rab5A predicts metastasis and poor prognosis in colorectal cancer patients. PMID: 26261586 Ref: [Clinical characteristics and prognosis of colon cancer patient with extremely elevated carcinoembryonic antigen level]. PMID: 26499150 Ref: Interleukin-6 trans-signaling increases the expression of carcinoembryonic antigen-related cell adhesion molecules 5 and 6 in colorectal cancer cells. PMID: 26673628 Ref: Emerging Role and Targeting of Carcinoembryonic Antigen-related Cell Adhesion Molecule 6 (CEACAM6) in Human Malignancies. PMID: 27595061 |
Ref: A suggested guiding panel of seromarkers for efficient discrimination between primary and secondary human hepatocarcinoma. PMID: 26386723 Ref: Generation of a monoclonal antibody recognizing the CEACAM glycan structure and inhibiting adhesion using cancer tissue-originated spheroid as an antigen. PMID: 27098764 Ref: Risk Stratification in Patients with Stage II Colon Cancer. PMID: 27380640 Ref: Neutrophil-lymphocyte ratio and CEA level as prognostic and predictive factors in colorectal cancer: A systematic review and meta-analysis. PMID: 27461614 Ref: Can serum dynamics of carcinoembryonic antigen level during neoadjuvant chemoradiotherapy in rectal cancer predict tumor response and recurrence? A multi-institutional retrospective study. PMID: 27464635 Ref: The Genome-Wide Analysis of Carcinoembryonic Antigen Signaling by Colorectal Cancer Cells Using RNA Sequencing. PMID: 27583792 Ref: [Assessment of the risk factors relating to lymph node metastasis in rectal cancer after neoadjuvant chemoradiotherapy and the clinical significance]. PMID: 27680075 Ref: [Expression and significance of serum microRNA-135a-5p level in colorectal cancer]. PMID: 27998467 |
Ref: Enhanced colorectal cancer metastases in the alcohol-injured liver. PMID: 28168393 Ref: Tumour suppressor EP300, a modulator of paclitaxel resistance and stemness, is downregulated in metaplastic breast cancer. PMID: 28341962 Ref: Early Assessment of Colorectal Cancer by Quantifying Circulating Tumor Cells in Peripheral Blood: ECT2 in Diagnosis of Colorectal Cancer. PMID: 28362321 Ref: [Predictive value of combination detection of tissue Pgp1 expression and preoperative serum CEA level for colorectal cancer]. PMID: 28440527 Ref: Carcinoembryonic antigen directed PET-CECT scanning for postoperative surveillance of colorectal cancer. PMID: 28444968 Ref: Identification of CEA-interacting proteins in colon cancer cells and their changes in expression after irradiation. PMID: 28881503 Ref: EphA2 signaling is impacted by carcinoembryonic antigen cell adhesion molecule 1-L expression in colorectal cancer liver metastasis in a cell context-dependent manner. PMID: 29262644 |
Ref: Which Patients with Isolated Para-aortic Lymph Node Metastasis Will Truly Benefit from Extended Lymph Node Dissection for Colon Cancer? PMID: 28707461 Ref: Clinicopathologic Significance of Intestinal-type Molecules' Expression and Different EGFR Gene Status in Pulmonary Adenocarcinoma. PMID: 29489510 Ref: Biomarker expression in rectal cancer tissue before and after neoadjuvant therapy. PMID: 29615840 Ref: Predictors of Survival after Yttrium-90 Radioembolization for Colorectal Cancer Liver Metastases. PMID: 29754852 Ref: Serum-derived carcinoembryonic antigen (CEA) activates fibroblasts to induce a local re-modeling of the extracellular matrix that favors the engraftment of CEA-expressing tumor cells. PMID: 29756328 Ref: FBW7 suppresses metastasis of colorectal cancer by inhibiting HIF1alpha/CEACAM5 functional axis. PMID: 29910683 Ref: Circulating miR-338-5p is a potential diagnostic biomarker in colorectal cancer. PMID: 29952077 Ref: Evaluation of the Relationship between Carcinoembryonic Antigen and TNM Stage in Colorectal Cancer. PMID: 30002575 Ref: Nisin, a potent bacteriocin and anti-bacterial peptide, attenuates expression of metastatic genes in colorectal cancer cell lines. PMID: 30017942 Ref: Clinical Value of CXCL5 for Determining of Colorectal Cancer PMID: 30255816 Ref: The clincopathological variables to differentiate the nature of isolated pulmonary nodules in patients who received curative surgery for colorectal cancer. PMID: 30262438 |