Primary Site >> Colorectal Cancer
Gene >> CEACAM1
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Ref: K cell mediated lysis of cultured colon carcinoma and urinary bladder carcinoma cells induced by monospecific antisera against carcinoembryonic antigen (CEA) and two CEA-related normal glycoproteins. PMID: 873641 |
Ref: Biosynthesis of carcinoembryonic antigen (CEA) gene family members expressed in human tumor cell lines: evidence for cleavage of the glycosyl phosphatidyl inositol (GPI) anchor by GPI-PLC and GPI-PLD. PMID: 1815506 |
Ref: Biliary glycoprotein, a potential human cell adhesion molecule, is down-regulated in colorectal carcinomas. PMID: 7504281 Ref: Antiserum to carcinoembryonic antigen recognizes a phosphotyrosine-containing protein in human colon cancer cell lines. PMID: 7680008 Ref: Determination of the specificities of monoclonal antibodies recognizing members of the CEA family using a panel of transfectants. PMID: 7690348 Ref: Differential regulation of carcinoembryonic antigen and biliary glycoprotein by gamma-interferon. PMID: 8453631 |
Ref: Transcriptional control of the human biliary glycoprotein gene, a CEA gene family member down-regulated in colorectal carcinomas. PMID: 8055923 |
Ref: Association of pp60c-src with biliary glycoprotein (CD66a), an adhesion molecule of the carcinoembryonic antigen family downregulated in colorectal carcinomas. PMID: 7478590 Ref: Inhibition of colonic tumor cell growth by biliary glycoprotein. PMID: 8570189 |
Ref: Role of interferon regulatory factor-1 in the induction of biliary glycoprotein (cell CAM-1) by interferon-gamma. PMID: 8910434 |
Ref: A colonic tissue architecture assay applied to human colon carcinoma cells. PMID: 9028835 Ref: Decreased expression of biliary glycoprotein in hepatocellular carcinomas. PMID: 9036863 Ref: Down-regulation of carcinoembryonic antigen family member 2 expression is an early event in colorectal tumorigenesis. PMID: 9135022 Ref: Several carcinoembryonic antigens (CD66) serve as receptors for gonococcal opacity proteins. PMID: 9151893 Ref: Expression of CD66a (human C-CAM) and other members of the carcinoembryonic antigen gene family of adhesion molecules in human colorectal adenomas. PMID: 9192807 Ref: Optimal ratios of biliary glycoprotein isoforms required for inhibition of colonic tumor cell growth. PMID: 9205090 Ref: Dysregulation of carcinoembryonic antigen group members CGM2, CD66a (biliary glycoprotein), and nonspecific cross-reacting antigen in colorectal carcinomas. Comparative analysis by northern blot and in situ hybridization. PMID: 9250164 Ref: Biliary glycoprotein is overexpressed in human colon cancer cells with high metastatic potential. PMID: 9834361 |
Ref: Expression of biliary glycoprotein (CD66a) in normal and malignant breast epithelial cells. PMID: 9858884 |
Ref: The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues. PMID: 10202129 Ref: C-CAM1 expression: differential effects on morphology, differentiation state and suppression of human PC-3 prostate carcinoma cells. PMID: 10359532 Ref: Comparison of expression patterns and cell adhesion properties of the mouse biliary glycoproteins Bbgp1 and Bbgp2. PMID: 10491101 Ref: cis-Determinants in the cytoplasmic domain of CEACAM1 responsible for its tumor inhibitory function. PMID: 10523833 |
Ref: Induction of cytotoxic T cells and their antitumor activity in mice transgenic for carcinoembryonic antigen. PMID: 10946810 |
Ref: Signal transduction by the CEACAM1 tumor suppressor. Phosphorylation of serine 503 is required for growth-inhibitory activity. PMID: 11278391 Ref: The CEACAM1-L Ser503 residue is crucial for inhibition of colon cancer cell tumorigenicity. PMID: 11313949 Ref: Frequent p53 mutation in brain (fetal)-type glycogen phosphorylase positive foci adjacent to human 'de novo' colorectal carcinomas. PMID: 11384100 |
Ref: Genetic pathways of 'de novo' colorectal carcinomas with reference to fetal-type glycogen phosphorylase positive foci. PMID: 12469186 Ref: Expression of CEACAM6 in resectable colorectal cancer: a factor of independent prognostic significance. PMID: 14512395 Ref: Interferon-gamma tempers the expression of carcinoembryonic antigen family molecules in human colon cells: a possible role in innate mucosal defence. PMID: 14636419 |
Ref: The human tumor suppressor CEACAM1 modulates apoptosis and is implicated in early colorectal tumorigenesis. PMID: 15568039 Ref: CEACAM1 and hyperplastic polyps: new links in the chain of events leading to colon cancer. PMID: 15602572 |
Ref: Selection, affinity maturation, and characterization of a human scFv antibody against CEA protein. PMID: 16504122 Ref: Deletion of the carcinoembryonic antigen-related cell adhesion molecule 1 (Ceacam1) gene contributes to colon tumor progression in a murine model of carcinogenesis. PMID: 16619040 Ref: Biomarker selection for detection of occult tumour cells in lymph nodes of colorectal cancer patients using real-time quantitative RT-PCR. PMID: 16755296 |
Ref: Up-regulation of tumor suppressor carcinoembryonic antigen-related cell adhesion molecule 1 in human colon cancer Caco-2 cells following repetitive exposure to dietary levels of a polyphenol-rich chokeberry juice. PMID: 16860979 Ref: CEACAM1 impedes thyroid cancer growth but promotes invasiveness: a putative mechanism for early metastases. PMID: 17057731 |
Ref: The CEACAM1-mediated apoptosis pathway is activated by CEA and triggers dual cleavage of CEACAM1. PMID: 18278069 Ref: Glycosylation-dependent interactions of C-type lectin DC-SIGN with colorectal tumor-associated Lewis glycans impair the function and differentiation of monocyte-derived dendritic cells. PMID: 18292560 Ref: Intestinal tumor progression is promoted by decreased apoptosis and dysregulated Wnt signaling in Ceacam1-/- mice. PMID: 18454175 Ref: Genetic construction, expression, and characterization of a single chain anti-CEA antibody fused to cytosine deaminase from yeast. PMID: 18497986 Ref: Whole genome exon arrays identify differential expression of alternatively spliced, cancer-related genes in lung cancer. PMID: 18927117 |
Ref: Contribution of intestinal epithelial cells to innate immunity of the human gut--studies on polarized monolayers of colon carcinoma cells. PMID: 19170965 Ref: Discovery of fully human anti-MET monoclonal antibodies with antitumor activity against colon cancer tumor models in vivo. PMID: 19308290 |
Ref: The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the "Fountain of Youth" to mediate healthful aging. PMID: 20227497 |
Ref: Genetic alterations and expression pattern of CEACAM1 in colorectal adenomas and cancers. PMID: 20524097 Ref: Colorectal cancer in the cotton top tamarin (Saguinus oedipus): how do they evade liver metastasis? PMID: 20645001 Ref: Re-expression of CEACAM1 long cytoplasmic domain isoform is associated with invasion and migration of colorectal cancer. PMID: 21413011 Ref: Phylogenetic discordance of human and canine carcinoembryonic antigen (CEA, CEACAM) families, but striking identity of the CEA receptors will impact comparative oncology studies. PMID: 21436956 Ref: A novel anti-CEACAM5 monoclonal antibody, CC4, suppresses colorectal tumor growth and enhances NK cells-mediated tumor immunity. PMID: 21731662 Ref: Hollow spheroids beyond the invasive margin indicate the malignant potential of colorectal cancer. PMID: 22021784 |
Ref: MDR-1-overexpression in HT 29 colon cancer cells grown in SCID mice. PMID: 22154301 Ref: [Human carcinoembryonic antigen family proteins, structure and function]. PMID: 22922152 Ref: Loss of expression of the tumor suppressor CEACAM1 links different hereditary colorectal carcinoma subtypes to the genesis of sporadic colorectal carcinoma. PMID: 23038226 Ref: Stromal CEACAM1 expression regulates colorectal cancer metastasis. PMID: 23170281 |
Ref: Host-related carcinoembryonic antigen cell adhesion molecule 1 promotes metastasis of colorectal cancer. PMID: 22469976 Ref: Oncogenic Wnt/beta-catenin signalling pathways in the cancer-resistant epididymis have implications for cancer research. PMID: 23155044 Ref: Development and evaluation of a novel anti-colorectal cancer monoclonal antibody, WL5. PMID: 23376714 |
Ref: Progress of cancer research on astrocyte elevated gene-1/Metadherin (Review). PMID: 25009642 |
Ref: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. PMID: 25363763 Ref: CEACAM1 and hollow spheroid formation modulate the chemosensitivity of colorectal cancer to 5-fluorouracil. PMID: 25547406 Ref: P4H9-detected molecule expression on spindle-shaped fibroblasts indicates malignant phenotype of colorectal cancer. PMID: 26469833 Ref: Emerging Role and Targeting of Carcinoembryonic Antigen-related Cell Adhesion Molecule 6 (CEACAM6) in Human Malignancies. PMID: 27595061 |
Ref: Carcinoembryonic Antigen Cell Adhesion Molecule 1 long isoform modulates malignancy of poorly differentiated colon cancer cells. PMID: 25666195 Ref: miR-137 Regulates the Tumorigenicity of Colon Cancer Stem Cells through the Inhibition of DCLK1. PMID: 26747706 |
Ref: Co-expression of TIM-3 and CEACAM1 promotes T cell exhaustion in colorectal cancer patients. PMID: 28038383 Ref: Overexpression of the transcription factor ATF3 with a regulatory molecular signature associates with the pathogenic development of colorectal cancer. PMID: 28402947 Ref: The Induction of Selected Wnt Target Genes by Tcf1 Mediates Generation of Tumorigenic Colon Stem Cells. PMID: 28467911 Ref: CEACAM1 is associated with recurrence after hepatectomy for colorectal liver metastasis. PMID: 29180203 Ref: EphA2 signaling is impacted by carcinoembryonic antigen cell adhesion molecule 1-L expression in colorectal cancer liver metastasis in a cell context-dependent manner. PMID: 29262644 |
Ref: Interferon regulatory factor 1 and a variant of heterogeneous nuclear ribonucleoprotein L coordinately silence the gene for adhesion protein CEACAM1. PMID: 29720400 Ref: Effect of CEACAM-1 knockdown in human colorectal cancer cells. PMID: 30008845 |