Primary Site >> Esophagus Cancer

Gene >> CDKN2B

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Ref: Frequent somatic mutation of the MTS1/CDK4I (multiple tumor suppressor/cyclin-dependent kinase 4 inhibitor) gene in esophageal squamous cell carcinoma.
PMID: 8012957
 Ref: Genomic DNA and messenger RNA expression alterations of the CDKN2B and CDKN2 genes in esophageal squamous carcinoma cell lines.
PMID: 7547637
Ref: Intragenic mutations of CDKN2B and CDKN2A in primary human esophageal cancers.
PMID: 8595411
 Ref: The molecular biology of esophageal carcinoma.
PMID: 8893331
Ref: [Analysis of the p16INK4, p15INK4B genes abnormality and the amplification of cyclin D1 gene in esophageal cancer].
PMID: 8920671
Ref: Growth suppression of esophageal cancer cells by p16INK4 and p15INK4B in vitro.
PMID: 9166536
Ref: Expression of cyclin D1, CDK4 and p27KIP1 is associated with the p16MTS1 gene status in human esophageal carcinoma cell lines.
PMID: 9414383
 Ref: Multiple types of aberrations in the p16 (INK4a) and the p15(INK4b) genes in 30 esophageal squamous-cell-carcinoma cell lines.
PMID: 9033652
 Ref: Aberrant methylation of p16INK4a and deletion of p15INK4b are frequent events in human esophageal cancer in Linxian, China.
PMID: 9934853
 Ref: p15(PAF), a novel PCNA associated factor with increased expression in tumor tissues.
PMID: 11313979
 Ref: Induction of G1 cell cycle arrest and P15INK4b expression by ECRG1 through interaction with Miz-1.
PMID: 15095404
Ref: Molecular biology of esophageal cancer.
PMID: 15138356
 Ref: Loss of heterozygosity on chromosome 10p14-p15 in colorectal carcinoma.
PMID: 16127298
 Ref: ECRG1, a novel candidate of tumor suppressor gene in the esophageal carcinoma, triggers a senescent program in NIH3T3 cells.
PMID: 16380648
 Ref: Establishment and characterization of a new xenograft-derived human esophageal squamous cell carcinoma cell line HKESC-4 of Chinese origin.
PMID: 17889704
 Ref: Genomic profiling of 766 cancer-related genes in archived esophageal normal and carcinoma tissues.
PMID: 18241037
Ref: Genome-wide copy number analysis in esophageal adenocarcinoma using high-density single-nucleotide polymorphism arrays.
PMID: 18519675
 Ref: 3,3'-Diindolylmethane suppresses growth of human esophageal squamous cancer cells by G1 cell cycle arrest.
PMID: 22293900
Ref: Expression of p14(ARF), p15(INK4b), p16(INK4a) and skp2 increases during esophageal squamous cell cancer progression.
PMID: 22970012
 Ref: Growth inhibitory effects and molecular mechanisms of crotoxin treatment in esophageal Eca-109 cells and transplanted tumors in nude mice.
PMID: 23202800
 Ref: Miz-1 promotes the proliferation of esophageal cancer cells via suppression of p21 and release of p21-arrested cyclin D1.
PMID: 27109891
 Ref: LncRNA SNHG7 promotes the proliferation of esophageal cancer cells and inhibits its apoptosis.
PMID: 29771415