Primary Site >> Stomach Cancer
Gene >> CDKN2A
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Ref: Highly frequent homozygous deletion of the p16 gene in esophageal cancer cell lines. PMID: 8093026 |
Ref: Mutation frequency of the p16/CDKN2 gene in primary cancers in the upper digestive tract. PMID: 7614482 Ref: Loss of heterozygosity on the short arm of chromosome 9 without p16 gene mutation in gastric carcinomas. PMID: 7775254 Ref: [Multiple gene alterations involved in the processor of human gastric carcinogenesis]. PMID: 8697090 |
Ref: Genetic status and expression of the cyclin-dependent kinase inhibitors in human gastric carcinoma cell lines. PMID: 8797888 Ref: Microsatellite instability-associated mutations associate preferentially with the intestinal type of primary gastric carcinomas in a high-risk population. PMID: 8840981 Ref: [Mutation frequency of the p16/CDKN2 gene and amplification of the cyclin E gene in human primary gastric carcinomas]. PMID: 8920672 Ref: Intragenic homozygous deletions of MTS1 gene in gastric cancer in Taiwan. PMID: 8957063 Ref: [Correlation of multiple gene changes with malignant phenotype of human gastric carcinoma]. PMID: 9275549 Ref: [Deletion and down-regulation of mts1/p16 gene in human gastric cancer]. PMID: 9387251 Ref: Decreased expression of p16 gene in gastric cancer. PMID: 21544452 |
Ref: Frequent detection of aberrant RNA transcripts of the CDKN2 gene in human gastric adenocarcinoma. PMID: 9139866 Ref: Infrequent alterations of the p16 (MTS-1) gene in human gastric cancer. PMID: 9222307 Ref: [Alteration of p15 and p16 gene in gastric cancer]. PMID: 9263516 Ref: High frequency of simultaneous loss of p16 and p16beta gene expression in squamous cell carcinoma of the esophagus but not in adenocarcinoma of the esophagus or stomach. PMID: 9333024 Ref: Alterations of p16INK4A and p15INK4B genes in gastric carcinomas. PMID: 9366289 Ref: [Effects of lanthanum and cerium on malignant proliferation and expression of tumor-related gene]. PMID: 9812584 Ref: [Exogenous mtsl/p16 gene suppresses tumorigenicity of human gastric cancer cell line]. PMID: 10920869 Ref: Altered expression of tumor suppressors p16 and Rb in gastric carcinogenesis. PMID: 27053889 |
Ref: Overexpression of mutant p53 and c-erbB-2 proteins and mutations of the p15 and p16 genes in human gastric carcinoma: with respect to histological subtypes and stages. PMID: 9570245 Ref: Quantitative analysis of CDKN2, p53 and retinoblastoma mRNA in human gastric carcinoma. PMID: 9664118 Ref: Alterations of CDKN2 (MTS1/p16INK4A) gene in paraffin-embedded tumor tissues of human stomach, lung, cervix and liver cancers. PMID: 9873831 Ref: Alterations of the p16/MTS1-tumor suppressor gene in gastric cancer. PMID: 9894245 |
Ref: Comparative genomic hybridization of cancer of the gastroesophageal junction: deletion of 14Q31-32.1 discriminates between esophageal (Barrett's) and gastric cardia adenocarcinomas. PMID: 9973227 Ref: The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer. PMID: 10073286 Ref: Distinct methylation pattern and microsatellite instability in sporadic gastric cancer. PMID: 10495421 Ref: Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype. PMID: 10554013 Ref: p53, p16 and RB expression in adenosquamous and squamous cell carcinomas of the stomach. PMID: 10605694 Ref: [Effect of compound Chinese drug bailong on the expression of tumor suppressor genes and relationship with prekallikrein activator signal pathway in human gastric carcinoma BGC82-3 cell line]. PMID: 11783178 |
Ref: Expression of tumor suppressor gene p16(INK4) products in primary gastric cancer. PMID: 10705239 Ref: Loss of p16 and p27 is associated with progression of human gastric cancer. PMID: 10779641 Ref: Correlation of p16 hypermethylation with p16 protein loss in sporadic gastric carcinomas. PMID: 10830779 Ref: The effects of recombinant RA538 and antisense c-myc adenovirus on tumor cells and the molecular mechanism concerned. PMID: 10837516 Ref: Methylation of specific CpG sites in the promoter region could significantly down-regulate p16(INK4a) expression in gastric adenocarcinoma. PMID: 10861481 Ref: Alterations and hypermethylation of the p14(ARF) gene in gastric cancer. PMID: 10925358 Ref: Molecular characteristics of eight gastric cancer cell lines established in Japan. PMID: 11107048 Ref: The suppression effect of light rare earth elements on proliferation of two cancer cell lines. PMID: 11351862 |
Ref: DNA methyltransferase expression and DNA methylation of CPG islands and peri-centromeric satellite regions in human colorectal and stomach cancers. PMID: 11146446 Ref: CpG island methylation in premalignant stages of gastric carcinoma. PMID: 11306456 Ref: Concurrent hypermethylation of multiple tumor-related genes in gastric carcinoma and adjacent normal tissues. PMID: 11413518 Ref: Site specificity and mechanism of oxidative DNA damage induced by carcinogenic catechol. PMID: 11470755 Ref: p16(INK4a) Promoter hypermethylation of non-tumorous tissue adjacent to gastric cancer is correlated with glandular atrophy and chronic inflammation. PMID: 11477571 Ref: DNA methylation status of hMLH1, p16(INK4a), and CDH1 is not associated with mRNA expression levels of DNA methyltransferase and DNA demethylase in gastric carcinomas. PMID: 11496321 Ref: CDKN2A novel mutation in a patient from a melanoma-prone family. PMID: 11595880 Ref: Expression, deletion [was deleton] and mutation of p16 gene in human gastric cancer. PMID: 11819820 Ref: [A study of the correlation between p16 protein expression and DNA quantitative analysis in human gastric carcinoma cells]. PMID: 11866976 |
Ref: Epstein-barr virus-positive gastric carcinoma demonstrates frequent aberrant methylation of multiple genes and constitutes CpG island methylator phenotype-positive gastric carcinoma. PMID: 11891177 Ref: Effect of cis-9, trans-11-conjugated linoleic acid on cell cycle of gastric adenocarcinoma cell line (SGC-7901). PMID: 11925596 Ref: The trefoil factor 1 participates in gastrointestinal cell differentiation by delaying G1-S phase transition and reducing apoptosis. PMID: 12034770 Ref: Detection of gene promoter hypermethylation in the tumor and serum of patients with gastric carcinoma. PMID: 12060614 Ref: Loss of expression of tumor suppressor p16(INK4) protein in human primary gastric cancer is related to the grade of differentiation. PMID: 12145426 Ref: Promoter methylation status of E-cadherin, hMLH1, and p16 genes in nonneoplastic gastric epithelia. PMID: 12163364 Ref: Distinct promoter hypermethylation of p16INK4a, CDH1, and RAR-beta in intestinal, diffuse-adherent, and diffuse-scattered type gastric carcinomas. PMID: 12210063 Ref: Preferential loss of Fhit expression in signet-ring cell and Krukenberg subtypes of gastric cancer. PMID: 12218081 Ref: Effects of retinoic acid on metastasis and its related proteins in gastric cancer cells in vivo and in vitro. PMID: 12230954 Ref: Effect of isoverbascoside, a phenylpropanoid glycoside antioxidant, on proliferation and differentiation of human gastric cancer cell. PMID: 12421475 Ref: Promoter hypermethylation of tumor-related genes in gastric intestinal metaplasia of patients with and without gastric cancer. PMID: 12448005 Ref: Reduced expression and promoter methylation of p16 gene in Epstein-Barr virus-associated gastric carcinoma. PMID: 12460459 Ref: Promoter methylations of p16INK4a and p14ARF genes in early and advanced gastric cancer. Correlations of the modes of their occurrence with histologic type. PMID: 12608655 |
Ref: P16 hypermethylation contributes to the characterization of gene inactivation profiles in primary gastric cancer. PMID: 12469165 Ref: p16 hypermethylation during gastric carcinogenesis of Wistar rats by N-methyl-N'-nitro-N-nitrosoguanidine. PMID: 12547284 Ref: p16Ink4a is overexpressed in H. pylori-associated gastritis and is correlated with increased epithelial apoptosis. PMID: 12603618 Ref: Methylation and mutation analysis of p16 gene in gastric cancer. PMID: 12632489 Ref: Relationship between the expression of human telomerase reverse transcriptase gene and cell cycle regulators in gastric cancer and its significance. PMID: 12632490 Ref: Studies on microsatellite instability in p16 gene and expression of hMSH2 mRNA in human gastric cancer tissues. PMID: 12632492 Ref: Concerted promoter hypermethylation of hMLH1, p16INK4A, and E-cadherin in gastric carcinomas with microsatellite instability. PMID: 12692837 Ref: Tumour suppressor gene expression correlates with gastric cancer prognosis. PMID: 12692839 Ref: Profile of aberrant CpG island methylation along multistep gastric carcinogenesis. PMID: 12695555 Ref: Global and non-random CpG-island methylation in gastric carcinoma associated with Epstein-Barr virus. PMID: 12708478 Ref: Relationship between inactivation of p16 gene and gastric carcinoma. PMID: 12717828 Ref: Profile of aberrant CpG island methylation along the multistep pathway of gastric carcinogenesis. PMID: 12746473 Ref: Exogenous wild-type p16INK4A gene induces delayed cell proliferation and promotes chemosensitivity through decreased pRB and increased E2F-1 expressions. PMID: 12792810 Ref: Detection of p16 promoter hypermethylation in serum of gastric cancer patients. PMID: 12824886 Ref: p53 and p14 increase sensitivity of gastric cells to H. pylori-induced apoptosis. PMID: 12870784 Ref: Relationship between alterations of p16(INK4a) and p14(ARF) genes of CDKN2A locus and gastric carcinogenesis. PMID: 12890389 Ref: Detection of methylation of human p16(Ink4a) gene 5'-CpG islands by electrochemical method coupled with linker-PCR. PMID: 12907744 Ref: Aberrant CpG island hypermethylation of chronic gastritis, in relation to aging, gender, intestinal metaplasia, and chronic inflammation. PMID: 14507661 Ref: DNA methylation of multiple genes in gastric carcinoma: association with histological type and CpG island methylator phenotype. PMID: 14556664 Ref: Identification of HRK as a target of epigenetic inactivation in colorectal and gastric cancer. PMID: 14695142 |
Ref: Promoter methylation status of tumor suppressor and tumor-related genes in neoplastic and non-neoplastic gastric epithelia. PMID: 14702190 Ref: 5-Aza-2'-deoxycitydine induces demethylation and up-regulates transcription of p16INK4A gene in human gastric cancer cell lines. PMID: 14733783 Ref: Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers. PMID: 14742272 Ref: Promoter hypermethylation of E-cadherin and its abnormal expression in Epstein-Barr virus-associated gastric carcinoma. PMID: 14750169 Ref: Epstein-barr virus-positive gastric carcinoma has a distinct protein expression profile in comparison with epstein-barr virus-negative carcinoma. PMID: 15014022 Ref: Frequent CpG island methylation in precursor lesions and early gastric adenocarcinomas. PMID: 15064707 Ref: [Relationship between alterations of p16INK4a and p14ARF genes of CDKN2A locus and gastric carcinogenesis]. PMID: 15231134 Ref: Detection of lymph node micrometastases by gene promoter hypermethylation in samples obtained by endosonography- guided fine-needle aspiration biopsy. PMID: 15240535 Ref: [Inhibitory effect of MUC2 antisense oligodeoxynucleotide with lipofectin on human gastric cancer cell proliferation]. PMID: 15248919 Ref: High-throughput method for detecting DNA methylation. PMID: 15262448 Ref: Detection of aberrant methylation as a tumor marker in serum of patients with gastric cancer. PMID: 15330201 Ref: Comparison of methylation-specific polymerase chain reaction (MSP) with reverse transcriptase-polymerase chain reaction (RT-PCR) in peripheral blood of gastric cancer patients. PMID: 15334633 Ref: High-density methylation of p14ARF and p16INK4A in Epstein-Barr virus-associated gastric carcinoma. PMID: 15352040 Ref: Loss of p16/CDKN2A protein in Epstein-Barr virus-associated gastric carcinoma. PMID: 15459500 Ref: Expression of Dnmt1, demethylase, MeCP2 and methylation of tumor-related genes in human gastric cancer. PMID: 15526354 Ref: Microarray-based method for detecting methylation changes of p16(Ink4a) gene 5'-CpG islands in gastric carcinomas. PMID: 15534905 Ref: In situ analysis of p16/INK4 promoter hypermethylation in esophageal carcinoma and gastric carcinoma. PMID: 15612883 Ref: [Allicin induced cell cycle arrest in human gastric cancer cell lines]. PMID: 15634516 |
Ref: Relationship between CDX2 gene methylation and dietary factors in gastric cancer patients. PMID: 15498792 Ref: [Expression and significance of cell cycle regulators in gastric carcinoma]. PMID: 15694028 Ref: Loss of p16 protein defines high-risk patients with gastrointestinal stromal tumors: a tissue microarray study. PMID: 15701851 Ref: Prognostic significance of CpG island methylator phenotype and microsatellite instability in gastric carcinoma. PMID: 15701853 Ref: Clinicopathologic and protein expression differences between cardia carcinoma and noncardia carcinoma of the stomach. PMID: 15726543 Ref: CGMIM: automated text-mining of Online Mendelian Inheritance in Man (OMIM) to identify genetically-associated cancers and candidate genes. PMID: 15796777 Ref: Nuclear factor-kappaB activation correlates with better prognosis and Akt activation in human gastric cancer. PMID: 15814628 Ref: Expression of p16 gene and Rb protein in gastric carcinoma and their clinicopathological significance. PMID: 15818729 Ref: Detection of p16 hypermethylation in gastric carcinomas using a seminested methylation-specific PCR. PMID: 15859515 Ref: Studies on inducing apoptosis effects and mechanism of CIK cells for MGC-803 gastric cancer cell lines. PMID: 15869451 Ref: Potential diagnostic and prognostic values of detecting promoter hypermethylation in the serum of patients with gastric cancer. PMID: 15942635 Ref: Comparison of serum aberrant methylation and conventional tumor markers in gastric cancer patients. PMID: 16001680 Ref: Whole-genome analyses of loss of heterozygosity and methylation analysis of four tumor-suppressor genes in N-methyl-N'-nitro-N-nitrosoguanidine-induced rat stomach carcinomas. PMID: 16053512 Ref: [Promoter methylation profile in gastric cancer]. PMID: 16163424 Ref: Polymorphism of p16 INK4A and cyclin D1 in adenocarcinomas of the upper gastrointestinal tract. PMID: 16163549 Ref: Cell-cycle regulators, bcl-2 and NF-kappaB in Epstein-Barr virus-positive gastric carcinomas. PMID: 16211221 Ref: Composite glandular-endocrine cell carcinomas of the stomach: clinicopathologic and methylation study. PMID: 16218931 Ref: Relationship between the extent of chromosomal losses and the pattern of CpG methylation in gastric carcinomas. PMID: 16224153 Ref: Concordant loss of MTAP and p16/CDKN2A expression in gastroesophageal carcinogenesis: evidence of homozygous deletion in esophageal noninvasive precursor lesions and therapeutic implications. PMID: 16224217 Ref: Expression of tumor suppressor and tumor-related proteins in differentiated carcinoma, undifferentiated carcinoma with tubular component and pure undifferentiated carcinoma of the stomach. PMID: 16254038 Ref: Association of genetic polymorphisms of MK, IL-4, p16, p21, p53 genes and human gastric cancer in Taiwan. PMID: 16289646 |
Ref: Frequent p16 CpG island hypermethylation in primary remnant gastric cancer suggesting an independent carcinogenic pathway. PMID: 16465421 Ref: Early-onset gastric cancers have a different molecular expression profile than conventional gastric cancers. PMID: 16474375 Ref: Accumulation of DNA methylation is associated with tumor stage in gastric cancer. PMID: 16475210 Ref: Alterations of tumor suppressor and tumor-related genes in the development and progression of gastric cancer. PMID: 16482617 Ref: Hypermethylation of hMLH1, HPP1, p14(ARF), p16(INK4A) and APC in primary adenocarcinomas of the small bowel. PMID: 16619216 Ref: P16 protein abnormality in Epstein-Barr virus-associated gastric carcinomas. PMID: 16619489 Ref: [Difference in methylation of genomic DNA between gastric primary cancer and lymph nodes with metastatic gastric cancer]. PMID: 16681882 Ref: CpG island methylation status in gastric carcinoma with and without infection of Epstein-Barr virus. PMID: 16707594 Ref: DNA methylation as a marker for the past and future. PMID: 16799880 Ref: Synergic antiproliferative effect of DNA methyltransferase inhibitor in combination with anticancer drugs in gastric carcinoma. PMID: 16805821 Ref: Correlation between serum DNA methylation and prognosis in gastric cancer patients. PMID: 16821608 Ref: [Quercetin inhibits growth and induces apoptosis of human gastric carcinoma cells]. PMID: 16948901 Ref: Multiple tumor suppressor genes are increasingly methylated with age in non-neoplastic gastric epithelia. PMID: 16952303 Ref: [Expression of tissue microarray p53, p16 and cyclooxygenase-2 in gastric cancer]. PMID: 17074152 Ref: An inverse correlation between Interleukin-6 and select gene promoter methylation in patients with gastric cancer. PMID: 17139167 Ref: Folate levels in mucosal tissue but not methylenetetrahydrofolate reductase polymorphisms are associated with gastric carcinogenesis. PMID: 17171786 |
Ref: Immunohistochemical analysis of pRb2/p130, VEGF, EZH2, p53, p16(INK4A), p27(KIP1), p21(WAF1), Ki-67 expression patterns in gastric cancer. PMID: 16998811 Ref: p73 gene promoter methylation in Epstein-Barr virus-associated gastric carcinoma. PMID: 17058198 Ref: [Hierarchical clustering analysis to detect associations between clinical and pathological features of gastric tumors and hypermethylation of suppressor genes]. PMID: 17369979 Ref: Molecular analysis of primary gastric cancer, corresponding xenografts, and 2 novel gastric carcinoma cell lines reveals novel alterations in gastric carcinogenesis. PMID: 17376510 Ref: Risk prediction of gastric cancer by analysis of aberrant DNA methylation in non-neoplastic gastric epithelium. PMID: 17438355 Ref: Constitutive phosphorylation of the FOXO1A transcription factor as a prognostic variable in gastric cancer. PMID: 17491598 Ref: Potential advantages of DNA methyltransferase 1 (DNMT1)-targeted inhibition for cancer therapy. PMID: 17571247 Ref: Clinical application of methylation specific-polymerase chain reaction in serum of patients with gastric cancer. PMID: 17591100 Ref: Aberrant methylation of multiple genes in gastric carcinomas. PMID: 17652530 Ref: Expression of Fhit, Mlh1, p16INK4A and E-cadherin in early gastric neoplasia: Correlation with histological grade and gastric phenotype. PMID: 17671701 Ref: Pterostilbene induces apoptosis and cell cycle arrest in human gastric carcinoma cells. PMID: 17696482 Ref: Methylation of tumor-related genes in neoadjuvant-treated gastric cancer: relation to therapy response and clinicopathologic and molecular features. PMID: 17785563 Ref: Metastatic suppressor genes inactivated by aberrant methylation in gastric cancer. PMID: 17963294 Ref: Expression of anion exchanger 1 sequestrates p16 in the cytoplasm in gastric and colonic adenocarcinoma. PMID: 17971901 Ref: Aberrant methylation of p16 predicts candidates for 5-fluorouracil-based adjuvant therapy in gastric cancer patients. PMID: 18008030 Ref: Re-expression of methylation-induced tumor suppressor gene silencing is associated with the state of histone modification in gastric cancer cell lines. PMID: 18069755 Ref: Genetic and epigenetic markers to identify high risk patients for multiple early gastric cancers after treatment with endoscopic mucosal resection. PMID: 18398497 |
Ref: The influence of promoter polymorphism of nuclear factor-erythroid 2-related factor 2 gene on the aberrant DNA methylation in gastric epithelium. PMID: 18097597 Ref: CpG island hypermethylation of tumor-suppressor genes in H. pylori-infected non-neoplastic gastric mucosa is linked with gastric cancer risk. PMID: 18205664 Ref: Methylation pattern analysis using high-throughput microarray of solid-phase hyperbranched rolling circle amplification products. PMID: 18228535 Ref: p16 promoter hypermethylation: a useful serum marker for early detection of gastric cancer. PMID: 18395906 Ref: Increased frequency of CpG island methylator phenotype and CDH1 methylation in a gastric cancer high-risk region of china. PMID: 18607505 Ref: Methylation status of ANAPC1, CDKN2A and TP53 promoter genes in individuals with gastric cancer. PMID: 18622497 Ref: [Gene methylation patterns in digestive tumors]. PMID: 18769787 Ref: Epstein-Barr virus and gastric carcinoma--viral carcinogenesis through epigenetic mechanisms. PMID: 18784828 Ref: Reprimo as a potential biomarker for early detection in gastric cancer. PMID: 18829507 Ref: [Effects of sodium butyrate on proliferation of human gastric cancer cells and expression of p16 gene]. PMID: 18844115 Ref: [Epstein-Barr virus infection and p16(INK4a) overexpression in gastric adenocarcinoma]. PMID: 19105332 Ref: DNA methylation profile in diffuse type gastric cancer: evidence for hypermethylation of the BRCA1 promoter region in early-onset gastric carcinogenesis. PMID: 19399343 |
Ref: E2F promoter-regulated oncolytic adenovirus with p16 gene induces cell apoptosis and exerts antitumor effect on gastric cancer. PMID: 19034663 Ref: DNA methylation status is inversely correlated with green tea intake and physical activity in gastric cancer patients. PMID: 19170207 Ref: FoxM1 is up-regulated in gastric cancer and its inhibition leads to cellular senescence, partially dependent on p27 kip1. PMID: 19235838 Ref: Biological significance of promoter hypermethylation of tumor-related genes in patients with gastric carcinoma. PMID: 19336228 Ref: RhoA regulates G1-S progression of gastric cancer cells by modulation of multiple INK4 family tumor suppressors. PMID: 19372585 Ref: Chronic nonsteroidal anti-inflammatory drug (NSAID) use suppresses multiple CpG islands hyper methylation (CIHM) of tumor suppressor genes in the human gastric mucosa. PMID: 19432886 Ref: Promoter hypermethylation of multiple genes in early gastric adenocarcinoma and precancerous lesions. PMID: 19695681 Ref: Effect of polymorphisms of IL-17A, -17F and MIF genes on CpG island hyper-methylation (CIHM) in the human gastric mucosa. PMID: 19724898 Ref: [Effects of 5-Aza-2'-deoxycytidine and trichostatin A on P16, hMLH1 and MGMT genes and DNA methylation in human gastric cancer cells]. PMID: 19742343 Ref: Expression of p53, p21 and p16 does not correlate with response to preoperative chemoradiation in gastric carcinoma. PMID: 19760973 Ref: Promoter histone H3 lysine 9 di-methylation is associated with DNA methylation and aberrant expression of p16 in gastric cancer cells. PMID: 19787243 Ref: [Effect of weikangning on growth and cell cycle regulators of gastric cancer cell]. PMID: 20329612 Ref: Expression of cytoplasmic p16 and anion exchanger 1 is associated with the invasion and absence of lymph metastasis in gastric carcinoma. PMID: 21475808 |
Ref: The histone demethylase RBP2 Is overexpressed in gastric cancer and its inhibition triggers senescence of cancer cells. PMID: 19850045 Ref: Anticancer bioactive peptide suppresses human gastric cancer growth through modulation of apoptosis and the cell cycle. PMID: 19956858 Ref: Aberrant gene methylation in the lymph nodes provides a possible marker for diagnosing micrometastasis in gastric cancer. PMID: 19957042 Ref: Gastrin suppresses the interdependent expression of p16 and anion exchanger 1 favoring growth inhibition of gastric cancer cells. PMID: 20020491 Ref: Induction of anion exchanger-1 translation and its opposite roles in the carcinogenesis of gastric cancer cells and differentiation of K562 cells. PMID: 20062076 Ref: The presence of JC virus in gastric carcinomas correlates with patient's age, intestinal histological type and aberrant methylation of tumor suppressor genes. PMID: 20081806 Ref: Helicobacter pylori and EBV in gastric carcinomas: methylation status and microsatellite instability. PMID: 20082476 Ref: Association between IL-17A, -17F and MIF polymorphisms predispose to CpG island hyper-methylation in gastric cancer. PMID: 20127054 Ref: CpG island promoter methylation (CIHM) status of tumor suppressor genes correlates with morphological appearances of gastric cancer. PMID: 20150642 Ref: Increased number of CpG island hypermethylation in tumor suppressor genes of non-neoplastic gastric mucosa correlates with higher risk of gastric cancer. PMID: 20150736 Ref: BMI1 and Mel-18 oppositely regulate carcinogenesis and progression of gastric cancer. PMID: 20170541 Ref: Molecular analysis of gastric differentiated-type intramucosal and submucosal cancers. PMID: 20178104 Ref: Evaluation of cell cycle protein expression in gastric cancer: cyclin B1 expression and its prognostic implication. PMID: 20334896 Ref: Role of Helicobacter pylori infection in aberrant DNA methylation along multistep gastric carcinogenesis. PMID: 20345486 Ref: [Gastric carcinoma and chronic gastritis: epigenetic regulation of CDH1 (E-Cadherin), CDKN2A (p16INK4A), PTGS2 (COX-2) and EGFR genes through methylation]. PMID: 20353702 Ref: Association between cyclin D1 polymorphism with CpG island promoter methylation status of tumor suppressor genes in gastric cancer. PMID: 20397048 Ref: CDKN2A promoter methylation is related to the tumor location and histological subtype and associated with Helicobacter pylori flaA(+) strains in gastric adenocarcinomas. PMID: 20402675 Ref: BCL2L10 is frequently silenced by promoter hypermethylation in gastric cancer. PMID: 20428828 Ref: Up-regulation of activation-induced cytidine deaminase causes genetic aberrations at the CDKN2b-CDKN2a in gastric cancer. PMID: 20637757 Ref: Methylation of the p16 gene is frequently detected in lymphatic-invasive gastric cancer. PMID: 20683001 Ref: Constitutive activation of glycogen synthase kinase-3beta correlates with better prognosis and cyclin-dependent kinase inhibitors in human gastric cancer. PMID: 20704706 Ref: Oncogenic role of the chromobox protein CBX7 in gastric cancer. PMID: 20723236 Ref: Lack of p16 gene mutations in gastric cancers in Kashmir. PMID: 20843112 Ref: Glycogen synthase kinase-3beta does not correlate with the expression and activity of beta-catenin in gastric cancer. PMID: 20854473 Ref: MTHFR C677T polymorphism and differential methylation status in gastric cancer: an association with Helicobacter pylori infection. PMID: 20957490 Ref: EBV-infection in cardiac and non-cardiac gastric adenocarcinomas is associated with promoter methylation of p16, p14 and APC, but not hMLH1. PMID: 20978327 Ref: Polycomb CBX7 directly controls trimethylation of histone H3 at lysine 9 at the p16 locus. PMID: 21060834 Ref: S-adenosylmethionine inhibits the growth of cancer cells by reversing the hypomethylation status of c-myc and H-ras in human gastric cancer and colon cancer. PMID: 21152119 Ref: Epstein-Barr virus-specific methylation of human genes in gastric cancer cells. PMID: 21194482 Ref: The prognostic significance of whole blood global and specific DNA methylation levels in gastric adenocarcinoma. PMID: 21203466 Ref: [Clinicopathologic features and protein expression study of Epstein-Barr virus-associated gastric carcinoma in Guangzhou]. PMID: 21215093 Ref: Promoter methylation of p16, Runx3, DAPK and CHFR genes is frequent in gastric carcinoma. PMID: 21302620 Ref: Association between common genetic variants in pre-microRNAs and the clinicopathological characteristics and survival of gastric cancer patients. PMID: 22993637 |
Ref: Human ribosomal protein S13 promotes gastric cancer growth through down-regulating p27(Kip1). PMID: 19912438 Ref: Canine gastric carcinoma: immunohistochemical expression of cell cycle proteins (p53, p21, and p16) and heat shock proteins (Hsp27 and Hsp70). PMID: 20587688 Ref: Cetuximab enhances the activities of irinotecan on gastric cancer cell lines through downregulating the EGFR pathway upregulated by irinotecan. PMID: 21286718 Ref: Hypermethylation of tumor-related genes in Tunisian patients with gastric carcinoma: clinical and biological significance. PMID: 21308683 Ref: Downregulation of methylthioadenosin phosphorylase by homozygous deletion in gastric carcinoma. PMID: 21412930 Ref: Expression ratio of CCND1 to CDKN2A mRNA predicts RB1 status of cultured cancer cell lines and clinical tumor samples. PMID: 21447152 Ref: EBV-infection in cardiac and non-cardiac gastric adenocarcinomas is associated with promoter methylation of p16, p14 and APC, but not hMLH1. PMID: 21538028 Ref: Helicobacter pylori upregulates the expression of p16(INK4) in gastric cancer cells. PMID: 21830402 Ref: Aberrant DNA methylation of cancer-associated genes in gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST). PMID: 21831520 Ref: Inactivation of COX-2, HMLH1 and CDKN2A gene by promoter methylation in gastric cancer: relationship with histological subtype, tumor location and Helicobacter pylori genotype. PMID: 21849808 Ref: Global DNA methylation and tumor suppressor gene promoter methylation and gastric cancer risk in an Omani Arab population. PMID: 22126203 |
Ref: Characterization of the gene structure, functional significance, and clinical application of RNF180, a novel gene in gastric cancer. PMID: 21717426 Ref: Identification of protein expression signatures in gastric carcinomas using clustering analysis. PMID: 21777278 Ref: Prognostic significance of aberrant gene methylation in gastric cancer. PMID: 22206050 Ref: Germline promoter hypermethylation of tumor suppressor genes in gastric cancer. PMID: 22228973 Ref: Constitutive activation of STAT3 is predictive of poor prognosis in human gastric cancer. PMID: 22328012 Ref: 15-PGDH is reduced and induces apoptosis and cell cycle arrest in gastric carcinoma. PMID: 22416177 Ref: Integrase interactor 1 regulates proliferation, apoptosis and invasion in gastric cancer cells. PMID: 22490415 Ref: [Expression of multiple tumor suppressor gene p16 and its relationship with prognosis of gastric cancer patients]. PMID: 22490850 Ref: Association between p16, hMLH1 and E-cadherin promoter hypermethylation and intake of local hot salted tea and sun-dried foods in Kashmiris with gastric tumors. PMID: 22502664 Ref: Nucleosomes correlate with in vivo progression pattern of de novo methylation of p16 CpG islands in human gastric carcinogenesis. PMID: 22558275 Ref: Clinical potential of DNA methylation in gastric cancer: a meta-analysis. PMID: 22558417 Ref: High-throughput mutation profiling identifies frequent somatic mutations in advanced gastric adenocarcinoma. PMID: 22723903 Ref: Promoter methylation of tumor-related genes in gastric carcinogenesis. PMID: 22936446 Ref: Acceleration of gastric tumorigenesis through MKRN1-mediated posttranslational regulation of p14ARF. PMID: 23104211 Ref: [Genetic and epigenetic alterations in gastric carcinogenesis]. PMID: 23198549 |
Ref: Role of DNA methylation in the development of Epstein-Barr virus-associated gastric carcinoma. PMID: 23073987 Ref: Targeted inactivation of HDAC2 restores p16INK4a activity and exerts antitumor effects on human gastric cancer. PMID: 23175521 Ref: Cytotoxicity of 5-Aza-2'-deoxycytidine against gastric cancer involves DNA damage in an ATM-P53 dependent signaling pathway and demethylation of P16(INK4A). PMID: 23201008 Ref: Effects of 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine (PhIP) on histopathology, oxidative stress, and expression of c-fos, c-jun and p16 in rat stomachs. PMID: 23313794 Ref: Human papillomavirus-unrelated gastric type of cervical adenocarcinoma presenting with a metastatic ovarian tumor: report of a case. PMID: 23343707 Ref: Analysis of the methylation patterns of the p16 INK4A, p15 INK4B, and APC genes in gastric adenocarcinoma patients from a Brazilian population. PMID: 23504555 Ref: Diet folate, DNA methylation and polymorphisms in methylenetetrahydrofolate reductase in association with the susceptibility to gastric cancer. PMID: 23534741 Ref: Interleukin polymorphisms and differential methylation status in gastric cancer: an association with Helicobacter pylori infection. PMID: 23566094 Ref: Anti-cancer effects of newly developed chemotherapeutic agent, glycoconjugated palladium (II) complex, against cisplatin-resistant gastric cancer cells. PMID: 23672493 Ref: Somatostatin receptor 1, a novel EBV-associated CpG hypermethylated gene, contributes to the pathogenesis of EBV-associated gastric cancer. PMID: 23722468 Ref: miR-200b and miR-200c as prognostic factors and mediators of gastric cancer cell progression. PMID: 23995857 Ref: The utility of immunohistochemistry for providing genetic information on tumors. PMID: 24065374 Ref: Disappearance of Serum Methylated p16 Indicates Longer Survival in Patients with Gastric Cancer. PMID: 24156035 Ref: Potential Therapeutic Role of Hispidulin in Gastric Cancer through Induction of Apoptosis via NAG-1 Signaling. PMID: 24159347 Ref: Resveratrol inhibits the growth of gastric cancer by inducing G1 phase arrest and senescence in a Sirt1-dependent manner. PMID: 24278101 Ref: Aberrant DNA Methylation of P16, MGMT, and hMLH1 Genes in Combination with MTHFR C677T Genetic Polymorphism in gastric cancer. PMID: 24550949 |
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