Primary Site >> Stomach Cancer
Gene >> CDKN1A
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Ref: Tumor-associated antigen of spontaneous mammary tumor in rats. PMID: 6427720 |
Ref: Molecular biology of gastric cancer. PMID: 7676688 |
Ref: Inhibition of cell growth by transforming growth factor beta 1 is associated with p53-independent induction of p21 in gastric carcinoma cells. PMID: 8641969 Ref: The p53 gene is a potent determinant of chemosensitivity and radiosensitivity in gastric and colorectal cancers. PMID: 8642047 Ref: Genetic status and expression of the cyclin-dependent kinase inhibitors in human gastric carcinoma cell lines. PMID: 8797888 Ref: Expression of cyclin-dependent kinase inhibitor p21WAF1/CIP1 in non-neoplastic mucosa and neoplasia of the stomach: relationship with p53 status and proliferative activity. PMID: 8976868 |
Ref: Expression of p21 (waf1/cip1/sdi1), but not p53 protein, is a factor in the survival of patients with advanced gastric carcinoma. PMID: 9179052 Ref: Loss of p21WAF1/CIP1 expression correlates with disease progression in gastric carcinoma. PMID: 9184177 Ref: Evidence that expression of a mutated p53 gene attenuates apoptotic cell death in human gastric intestinal-type carcinomas in vivo. PMID: 9247603 Ref: Growth inhibition of cultured human gastric cancer cells by 9-cis-retinoic acid with induction of cdk inhibitor Waf1/Cip1/Sdi1/p21 protein. PMID: 9342842 Ref: Increase in proliferation and apoptosis of gastric epithelial cells early in the natural history of Helicobacter pylori infection. PMID: 9403720 Ref: Effect of Helicobacter pylori eradication on intestinal metaplasia and gastric epithelium proliferation. PMID: 9494859 Ref: Medico-genetic and cytogenetic study of a family with high predisposition to malignant disease in gastro-intestinal tract. PMID: 9505210 Ref: 5-Fluorouracil (5-FU) induced apoptosis in gastric cancer cell lines: role of the p53 gene. PMID: 14646558 |
Ref: Expression of p53 and p21WAF1/CIP1 proteins in gastric and esophageal cancers: comparison with mutations of the p53 gene. PMID: 9512119 Ref: Expression of cyclin dependent kinase inhibitor p21WAF1 alone and in combination with p27KIP1 shows prognostic value in gastric carcinoma. PMID: 9741540 Ref: Helicobacter pylori and Epstein-Barr virus infection and the p53 tumour suppressor pathway in gastric stump cancer compared with carcinoma in the non-operated stomach. PMID: 9930069 Ref: [Garlic oil induces differentiation and apoptosis of human gastric cancer cell line]. PMID: 10921020 |
Ref: Non-steroidal anti-inflammatory drug-induced apoptosis in gastric cancer cells is blocked by protein kinase C activation through inhibition of c-myc. PMID: 10027304 Ref: Effect of antisense human telomerase RNA transfection on the growth of human gastric cancer cell lines. PMID: 10049783 Ref: The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer. PMID: 10073286 Ref: Expression of cell-cycle regulators, cyclin E and p21WAF1/CIP1, potential prognostic markers for gastric cancer. PMID: 10218458 Ref: Helicobacter pylori inhibits the G1 to S transition in AGS gastric epithelial cells. PMID: 10344728 Ref: Rapid induction of p21WAF1 but delayed down-regulation of Cdc25A in the TGF-beta-induced cell cycle arrest of gastric carcinoma cells. PMID: 10376964 Ref: Adenovirus-mediated transfer of wild-type p53 gene results in apoptosis or growth arrest in human cultured gastric carcinoma cells. PMID: 10402231 Ref: Differential apoptosis by indomethacin in gastric epithelial cells through the constitutive expression of wild-type p53 and/or up-regulation of c-myc. PMID: 10403534 Ref: Effect of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (vesnarinone) on the growth of gastric cancer cell lines. PMID: 10403550 Ref: Inhibition of gastric cancer by camptothecin involves apoptosis and multiple cellular pathways. PMID: 10455888 Ref: TGF-beta-induced cell-cycle arrest through the p21(WAF1/CIP1)-G1 cyclin/Cdks-p130 pathway in gastric-carcinoma cells. PMID: 10508488 Ref: Mutated p53 protein expression and proliferative activity in advanced gastric cancer. PMID: 10522058 Ref: Expression of cell-cycle regulatory proteins cyclin D1, cyclin E, and their inhibitor p21 WAF1/CIP1 in gastric cancer. PMID: 10547573 Ref: Pharmacological inhibition of protein kinase C activity could induce apoptosis in gastric cancer cells by differential regulation of apoptosis-related genes. PMID: 10548353 Ref: Targeting molecular pathways with camptothecin as novel therapy for gastric cancer. PMID: 10554369 Ref: Reduced expression of p33(ING1) and the relationship with p53 expression in human gastric cancer. PMID: 10660101 Ref: [Effect of compound Chinese drug bailong on the expression of tumor suppressor genes and relationship with prekallikrein activator signal pathway in human gastric carcinoma BGC82-3 cell line]. PMID: 11783178 Ref: [Regulation of cell cycle by retinoic acid in gastric cancer cells]. PMID: 12548778 |
Ref: Mechanism for inactivation of the KIP family cyclin-dependent kinase inhibitor genes in gastric cancer cells. PMID: 10667572 Ref: Overexpression of protein kinase C-beta1 isoenzyme suppresses indomethacin-induced apoptosis in gastric epithelial cells. PMID: 10702201 Ref: Expression of p53 and p21waf1/cip1 in gastric carcinoma: lack of inter-relationship or correlation with prognosis. PMID: 10718178 Ref: Expressions of cell-cycle regulatory gene products in conventional gastric adenomas: possible immunohistochemical markers of malignant transformation. PMID: 10746668 Ref: Induction of apoptosis in human gastric cancer by sodium butyrate. PMID: 10810354 Ref: Bcl-2 accelerates retinoic acid-induced growth arrest and recovery in human gastric cancer cells. PMID: 10816444 Ref: Prognostic value of the cyclin-dependent kinase inhibitor p27Kip1 in gastric cancer. PMID: 10928108 Ref: [Gastric cancer and tumor growth regulation. Study of cell proliferation markers and protein complex p53/p21WAF1/CIP1/mdm-2]. PMID: 10962880 Ref: Deoxynybomycin is a selective anti-tumor agent inducing apoptosis and inhibiting topoisomerase I. PMID: 10993200 Ref: The suppression effect of light rare earth elements on proliferation of two cancer cell lines. PMID: 11351862 Ref: Effects of garlic oil on tumoragenecity and intercellular communication in human gastric cancer cell line. PMID: 18763119 |
Ref: Arsenic trioxide induces apoptosis in human gastric cancer cells through up-regulation of p53 and activation of caspase-3. PMID: 11146441 Ref: Caspase-mediated Cdk2 activation is a critical step to execute transforming growth factor-beta1-induced apoptosis in human gastric cancer cells. PMID: 11313870 Ref: Expression of p21(WAF1/CIP1) and p53 proteins in gastric carcinoma: its relationships with cell proliferation activity and prognosis. PMID: 11463497 Ref: Inhibition of proteasome function induced apoptosis in gastric cancer. PMID: 11477551 Ref: p21/waf1/cip1 in gastric cancer: associations with histopathological subtypes, lymphonodal metastasis, prognosis and p53 status. PMID: 11521990 Ref: Growth pattern and expressions of cell cycle regulator proteins p53 and p21WAF1/CIP1 in early gastric carcinoma. PMID: 11745255 Ref: Functional p53 is required for triptolide-induced apoptosis and AP-1 and nuclear factor-kappaB activation in gastric cancer cells. PMID: 11753684 Ref: Growth inhibition of gastric cancer cells by all-trans retinoic acid through arresting cell cycle progression. PMID: 11780391 Ref: Combined examination of p27(Kip1), p21(Waf1/Cip1) and p53 expression allows precise estimation of prognosis in patients with gastric carcinoma. PMID: 11903579 |
Ref: Expression and mutation analyses of P53R2, a newly identified p53 target for DNA repair in human gastric carcinoma. PMID: 11920641 Ref: Effect of cis-9, trans-11-conjugated linoleic acid on cell cycle of gastric adenocarcinoma cell line (SGC-7901). PMID: 11925596 Ref: Increased proliferative activity caused by loss of p21(WAF1/CIP1) expression and its clinical significance in patients with early-stage gastric carcinoma. PMID: 11932915 Ref: Different roles of p53 between Epstein-Barr virus-positive and -negative gastric carcinomas of matched histology. PMID: 11956816 Ref: Expression of cell-cycle related proteins in Helicobacter pylori gastritis and association with gastric carcinoma. PMID: 12088113 Ref: Novel target for induction of apoptosis by cyclo-oxygenase-2 inhibitor SC-236 through a protein kinase C-beta(1)-dependent pathway. PMID: 12203123 Ref: Effect of isoverbascoside, a phenylpropanoid glycoside antioxidant, on proliferation and differentiation of human gastric cancer cell. PMID: 12421475 Ref: Helicobacter pylori releases a factor(s) inhibiting cell cycle progression of human gastric cell lines by affecting cyclin E/cdk2 kinase activity and Rb protein phosphorylation through enhanced p27(KIP1) protein expression. PMID: 12441136 Ref: Synthetic retinoid CD437 induces cell-dependent cycle arrest by differential regulation of cell cycle associated proteins. PMID: 12529993 Ref: Immunohistochemical expression of TGF-beta1, p21WAF1, p53, Ki67, and angiogenesis in gastric carcinomas: a clinicopathologic study. PMID: 12794244 |
Ref: Mucosal high apoptotic activity and low p21WAF1/CIP1 expression and submucosal low proliferative activity in superficially spreading early gastric cancers: comparison with the penetrating growth type. PMID: 12588435 Ref: Aberrant signaling of TGF-beta1 by the mutant Smad4 in gastric cancer cells. PMID: 12860278 Ref: Prediction of lymph node metastasis by p53, p21(Waf1), and PCNA expression in esophageal cancer patients. PMID: 12866574 Ref: Prognostic significance of p21 and p53 expression in gastric cancer. PMID: 12872447 |
Ref: Upregulation of heme oxygenase-1 and p21 confers resistance to apoptosis in human gastric cancer cells. PMID: 14647439 Ref: Susceptibility to killer T cells of gastric cancer cells enhanced by Mitomycin-C involves induction of ATBF1 and activation of p21 (Waf1/Cip1) promoter. PMID: 14978340 Ref: BMP-2 modulates the proliferation and differentiation of normal and cancerous gastric cells. PMID: 15003517 Ref: Expression of p21(WAF1) and p53 and polymorphism of p21(WAF1) gene in gastric carcinoma. PMID: 15069711 Ref: p53 polymorphism and p21WAF1/CIP1 haplotype in the intestinal gastric cancer and the precancerous lesions. PMID: 15240512 Ref: Identification of novel genes associated with the response to 5-FU treatment in gastric cancer cell lines using a cDNA microarray. PMID: 15331170 Ref: High microvascular density is correlated with high VEGF, iNOS and COX-2 expression in penetrating growth-type early gastric carcinomas. PMID: 15569052 |
Ref: Histone H3 acetylation is associated with reduced p21(WAF1/CIP1) expression by gastric carcinoma. PMID: 15586362 Ref: Blocking effects of genistein on cell proliferation and possible mechanism in human gastric carcinoma. PMID: 15609399 Ref: [Expression and significance of cell cycle regulators in gastric carcinoma]. PMID: 15694028 Ref: Resveratrol regulates cellular PKC alpha and delta to inhibit growth and induce apoptosis in gastric cancer cells. PMID: 15744586 Ref: Induction of DMBT1 expression by reduced ERK activity during a gastric mucosa differentiation-like process and its association with human gastric cancer. PMID: 15760920 Ref: Loss of Klf4 in mice causes altered proliferation and differentiation and precancerous changes in the adult stomach. PMID: 15825076 Ref: Tissue microarray analysis of multiple gene expression in intestinal metaplasia, dysplasia and carcinoma of the stomach. PMID: 15842632 Ref: [Expression of cyclin dependent kinase inhibitors of KIP family in gastric cancer]. PMID: 16118517 Ref: RUNX3 suppresses gastric epithelial cell growth by inducing p21(WAF1/Cip1) expression in cooperation with transforming growth factor {beta}-activated SMAD. PMID: 16135801 Ref: Cell-cycle regulators, bcl-2 and NF-kappaB in Epstein-Barr virus-positive gastric carcinomas. PMID: 16211221 Ref: Effects of allitridi on cell cycle arrest of human gastric cancer cells. PMID: 16222732 Ref: A study on the prognostic value of cyclins D1 and E expression levels in resectable gastric cancer and on some correlations between cyclins expression, histoclinical parameters and selected protein products of cell-cycle regulatory genes. PMID: 16270527 Ref: p53-Independent negative regulation of p21/cyclin-dependent kinase-interacting protein 1 by the sonic hedgehog-glioma-associated oncogene 1 pathway in gastric carcinoma cells. PMID: 16322228 |
Ref: Lycopene supplementation prevents smoke-induced changes in p53, p53 phosphorylation, cell proliferation, and apoptosis in the gastric mucosa of ferrets. PMID: 16365067 Ref: TGF-beta signaling pathway inactivation and cell cycle deregulation in the development of gastric cancer: role of the beta-spectrin, ELF. PMID: 16650383 Ref: Selective inhibition of cell growth by activin in SNU-16 cells. PMID: 16718778 Ref: Histone deacetylase inhibitor, trichostatin A, increases the chemosensitivity of anticancer drugs in gastric cancer cell lines. PMID: 16865256 Ref: Relationship of hypoxia-inducible factor 1alpha and p21WAF1/CIP1 expression to cell apoptosis and clinical outcome in patients with gastric cancer. PMID: 17166265 Ref: Folate levels in mucosal tissue but not methylenetetrahydrofolate reductase polymorphisms are associated with gastric carcinogenesis. PMID: 17171786 |
Ref: Immunohistochemical analysis of pRb2/p130, VEGF, EZH2, p53, p16(INK4A), p27(KIP1), p21(WAF1), Ki-67 expression patterns in gastric cancer. PMID: 16998811 Ref: Mechanisms of growth arrest by zinc ribbon domain-containing 1 in gastric cancer cells. PMID: 17389617 Ref: Prognostic significance of p21WAF1/CIP1, p27Kip1, p53 and E-cadherin expression in gastric cancer. PMID: 17483253 Ref: [The relationship of mTOR signaling pathway and histone acetylation in human gastric cancer cell lines]. PMID: 17680526 Ref: Identification and characterization of a novel germ line p53 mutation in familial gastric cancer in the Japanese population. PMID: 17690113 |
Ref: Frequent epigenetic inactivation of hSRBC in gastric cancer and its implication in attenuated p53 response to stresses. PMID: 18059034 Ref: The influence of promoter polymorphism of nuclear factor-erythroid 2-related factor 2 gene on the aberrant DNA methylation in gastric epithelium. PMID: 18097597 Ref: Helicobacter pylori regulates p21(WAF1) by histone H4 acetylation. PMID: 18302936 Ref: E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer. PMID: 18328430 Ref: Anti-proliferative and chemosensitizing effects of luteolin on human gastric cancer AGS cell line. PMID: 18398671 Ref: Proteasome inhibitor MG-132 lowers gastric adenocarcinoma TMK1 cell proliferation via bone morphogenetic protein signaling. PMID: 18435911 Ref: Induction of G2/M arrest and apoptosis by water extract of Strychni Semen in human gastric carcinoma AGS cells. PMID: 18446845 Ref: E1A physically interacts with RUNX3 and inhibits its transactivation activity. PMID: 18570183 Ref: [Effects of sodium butyrate on proliferation and differentiation of human gastric carcinoma cell line AGS]. PMID: 18710616 Ref: Comparison of the prognostic value of a panel of tissue tumor markers and established clinicopathological factors in patients with gastric cancer. PMID: 18751407 Ref: Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis. PMID: 18827816 Ref: Extensive alteration in the expression profiles of TGFB pathway signaling components and TP53 is observed along the gastric dysplasia-carcinoma sequence. PMID: 18830930 |
Ref: Anticancer effect of celecoxib via COX-2 dependent and independent mechanisms in human gastric cancers cells. PMID: 18923901 Ref: Upregulation of the cycline kinase subunit CKS2 increases cell proliferation rate in gastric cancer. PMID: 19034516 Ref: Methylation of protocadherin 10, a novel tumor suppressor, is associated with poor prognosis in patients with gastric cancer. PMID: 19084528 Ref: Functional role of the KLF6 tumour suppressor gene in gastric cancer. PMID: 19101139 Ref: Functional links between clustered microRNAs: suppression of cell-cycle inhibitors by microRNA clusters in gastric cancer. PMID: 19153141 Ref: Pseudolaric acid B-induced apoptosis through p53-dependent pathway in human gastric carcinoma cells. PMID: 19219727 Ref: Eupatilin exhibits a novel anti-tumor activity through the induction of cell cycle arrest and differentiation of gastric carcinoma AGS cells. PMID: 19281788 Ref: Restoration of XAF1 expression induces apoptosis and inhibits tumor growth in gastric cancer. PMID: 19358264 Ref: RhoA regulates G1-S progression of gastric cancer cells by modulation of multiple INK4 family tumor suppressors. PMID: 19372585 Ref: Hispolon from Phellinus linteus has antiproliferative effects via MDM2-recruited ERK1/2 activity in breast and bladder cancer cells. PMID: 19477214 Ref: Arginine deiminase originating from Lactococcus lactis ssp. lactis American Type Culture Collection (ATCC) 7962 induces G1-phase cell-cycle arrest and apoptosis in SNU-1 stomach adenocarcinoma cells. PMID: 19624867 |
Ref: Synergistic antitumor effects of FGFR2 inhibitor with 5-fluorouracil on scirrhous gastric carcinoma. PMID: 19621385 Ref: The histone demethylase RBP2 Is overexpressed in gastric cancer and its inhibition triggers senescence of cancer cells. PMID: 19850045 Ref: The host defense peptide LL-37 activates the tumor-suppressing bone morphogenetic protein signaling via inhibition of proteasome in gastric cancer cells. PMID: 20054823 Ref: [Analysis of the P53 transcriptional activity in gastric cancer]. PMID: 20140870 Ref: Intracellular chloride regulates cell proliferation through the activation of stress-activated protein kinases in MKN28 human gastric cancer cells. PMID: 20205250 Ref: Evaluation of cell cycle protein expression in gastric cancer: cyclin B1 expression and its prognostic implication. PMID: 20334896 Ref: PTEN- and p53-mediated apoptosis and cell cycle arrest by FTY720 in gastric cancer cells and nude mice. PMID: 20506484 Ref: Tumor suppressor, AT motif binding factor 1 (ATBF1), translocates to the nucleus with runt domain transcription factor 3 (RUNX3) in response to TGF-beta signal transduction. PMID: 20599712 Ref: Absence of CIP1/KIP1 hypermethylation in gastric cancer patients from Northern Brazil. PMID: 20668328 |
Ref: Changes in the gene expression profile of gastric cancer cells in response to ibuprofen: a gene pathway analysis. PMID: 20548326 Ref: The G1 phase arrest and apoptosis by intrinsic pathway induced by valproic acid inhibit proliferation of BGC-823 gastric carcinoma cells. PMID: 21113745 Ref: Potent in vitro and in vivo antitumor effects of MDM2 inhibitor nutlin-3 in gastric cancer cells. PMID: 21205074 Ref: Antiproliferative mechanism of a cannabinoid agonist by cell cycle arrest in human gastric cancer cells. PMID: 21312237 Ref: RNA interference targeting raptor inhibits proliferation of gastric cancer cells. PMID: 21396933 Ref: CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth. PMID: 21397861 Ref: Down-regulation of miR-27a might inhibit proliferation and drug resistance of gastric cancer cells. PMID: 21569481 Ref: Arctigenin induces cell cycle arrest by blocking the phosphorylation of Rb via the modulation of cell cycle regulatory proteins in human gastric cancer cells. PMID: 21621647 Ref: Nitric oxide inhibits gastric cancer cell growth through the modulation of the Akt pathway. PMID: 21769431 Ref: Histone demethylase JMJD2B is required for tumor cell proliferation and survival and is overexpressed in gastric cancer. PMID: 22133676 |
Ref: Gastrokine 1 induces senescence through p16/Rb pathway activation in gastric cancer cells. PMID: 21676900 Ref: Epigenetic inactivation of paired box gene 5, a novel tumor suppressor gene, through direct upregulation of p53 is associated with prognosis in gastric cancer patients. PMID: 22105368 Ref: MiR-663, a microRNA targeting p21(WAF1/CIP1), promotes the proliferation and tumorigenesis of nasopharyngeal carcinoma. PMID: 22249270 Ref: Constitutive activation of STAT3 is predictive of poor prognosis in human gastric cancer. PMID: 22328012 Ref: 15-PGDH is reduced and induces apoptosis and cell cycle arrest in gastric carcinoma. PMID: 22416177 Ref: miR-124 inhibits cell proliferation in gastric cancer through down-regulation of SPHK1. PMID: 22450659 Ref: Integrase interactor 1 regulates proliferation, apoptosis and invasion in gastric cancer cells. PMID: 22490415 Ref: Investigation and identification of let-7a related functional proteins in gastric carcinoma by proteomics. PMID: 22596182 Ref: 5-Aza-2'-deoxycytidine induces cytotoxicity in BGC-823 cells via DNA methyltransferase 1 and 3a independent of p53 status. PMID: 22664909 Ref: ERK inhibition enhances TSA-induced gastric cancer cell apoptosis via NF-kappaB-dependent and Notch-independent mechanism. PMID: 22781708 Ref: ZIC1 modulates cell-cycle distributions and cell migration through regulation of sonic hedgehog, PI(3)K and MAPK signaling pathways in gastric cancer. PMID: 22799764 Ref: Differentially expressed proteins identified in overexpressed let-7a gastric carcinoma cells by two-dimensional polyacrylamide gel electrophoresis. PMID: 22968827 |
Ref: Cytotoxicity of 5-Aza-2'-deoxycytidine against gastric cancer involves DNA damage in an ATM-P53 dependent signaling pathway and demethylation of P16(INK4A). PMID: 23201008 Ref: Antitumor activity of cell-permeable RUNX3 protein in gastric cancer cells. PMID: 23230322 Ref: miR-17-5p/20a are important markers for gastric cancer and murine double minute 2 participates in their functional regulation. PMID: 23333058 Ref: Connexin32 inhibits gastric carcinogenesis through cell cycle arrest and altered expression of p21Cip1 and p27Kip1. PMID: 23351380 Ref: Nobiletin induces apoptosis and potentiates the effects of the anticancer drug 5-fluorouracil in p53-mutated SNU-16 human gastric cancer cells. PMID: 23441616 Ref: Acetyl-11-keto-beta-boswellic acid (AKBA) inhibits human gastric carcinoma growth through modulation of the Wnt/beta-catenin signaling pathway. PMID: 23500016 Ref: Growth-inhibitory activity of melatonin on murine foregastric carcinoma cells in vitro and the underlying molecular mechanism. PMID: 23564716 Ref: Excessive MET signaling causes acquired resistance and addiction to MET inhibitors in the MKN45 gastric cancer cell line. PMID: 23568717 Ref: [Effect of silencing AEG-1 with small interfering RNA on the proliferation and cell cycle of gastric carcinoma SGC-7901 cells]. PMID: 23648295 Ref: Upregulation of miR-370 contributes to the progression of gastric carcinoma via suppression of FOXO1. PMID: 23721824 Ref: MicroRNA-212 inhibits proliferation of gastric cancer by directly repressing retinoblastoma binding protein 2. PMID: 23794145 Ref: Epstein-Barr virus-encoded BARF1 promotes proliferation of gastric carcinoma cells through regulation of NF-kappaB. PMID: 23824821 Ref: Resveratrol inhibits the growth of gastric cancer by inducing G1 phase arrest and senescence in a Sirt1-dependent manner. PMID: 24278101 Ref: Transcriptomic changes induced by mycophenolic acid in gastric cancer cells. PMID: 24349619 Ref: Urushiol Induces Apoptosis via a p53-dependent Pathway in Human Gastric Cancer Cells. PMID: 25337543 |
Ref: Inhibition of mTOR signalling potentiates the effects of trichostatin A in human gastric cancer cell lines by promoting histone acetylation. PMID: 24030871 Ref: A novel tri-allelic insertion/deletion polymorphism in the promoter of p21(Waf1/Cip1) and the association with gastric cancer. PMID: 24387689 Ref: CEP55 contributes to human gastric carcinoma by regulating cell proliferation. PMID: 24390615 Ref: Involvement of BID translocation in glycyrrhetinic acid and 11-deoxy glycyrrhetinic acid-induced attenuation of gastric cancer growth. PMID: 24547973 Ref: Tangeretin, a citrus polymethoxyflavonoid, induces apoptosis of human gastric cancer AGS cells through extrinsic and intrinsic signaling pathways. PMID: 24573532 Ref: Antitumor activity of di-n-butyl-(2,6-difluorobenzohydroxamato)tin(IV) against human gastric carcinoma SGC-7901 cells via G2/M cell cycle arrest and cell apoptosis. PMID: 24643073 Ref: Genetic association of gastric cancer with miRNA clusters including the cancer-related genes MIR29, MIR25, MIR93 and MIR106: results from the EPIC-EURGAST study. PMID: 24643999 Ref: Chk1, but not Chk2, is responsible for G2/M phase arrest induced by diallyl disulfide in human gastric cancer BGC823 cells. PMID: 24650757 Ref: Differential expression of histone deacetylase and acetyltransferase genes in gastric cancer and their modulation by trichostatin A. PMID: 24668547 Ref: Specific anti-gastric cancer effects of a recombinant plasmid expressing nonstructural protein 1 of parvovirus H1. PMID: 24749129 Ref: Odd-skipped related 1 is a novel tumour suppressor gene and a potential prognostic biomarker in gastric cancer. PMID: 24931004 Ref: ADRM1 gene amplification is a candidate driver for metastatic gastric cancers. PMID: 24968865 Ref: Ablation of galectin-3 induces p27(KIP1)-dependent premature senescence without oncogenic stress. PMID: 24971481 Ref: Long noncoding RNA associated-competing endogenous RNAs in gastric cancer. PMID: 25124853 Ref: BAX and CDKN1A polymorphisms correlated with clinical outcomes of gastric cancer patients treated with postoperative chemotherapy. PMID: 25267570 Ref: [Anti-gastric cancer effect of melatonin and Bcl-2, Bax, p21 and p53 expression changes]. PMID: 25516522 |
Ref: Dysregulation of apoptotic signaling pathways by interaction of RPLP0 and cathepsin X/Z in gastric cancer. PMID: 25433997 Ref: Inhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells. PMID: 25609923 Ref: SP1-induced upregulation of the long noncoding RNA TINCR regulates cell proliferation and apoptosis by affecting KLF2 mRNA stability in gastric cancer. PMID: 25728677 Ref: Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer AGS and N PMID: 25767376 Ref: Sacituzumab Govitecan (IMMU-132), an Anti-Trop-2/SN-38 Antibody-Drug Conjugate: Characterization and Efficacy in Pancreatic, Gastric, and Other Cancers. PMID: 25915780 Ref: MHY-449, a novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivative, mediates oxidative stress-induced apoptosis in AGS human gastric cancer cells. PMID: 25998412 Ref: By recruiting HDAC1, MORC2 suppresses p21 Waf1/Cip1 in gastric cancer. PMID: 26098774 Ref: Equol inhibits proliferation of human gastric carcinoma cells via modulating Akt pathway. PMID: 26420965 |
Ref: Inhibition of class I histone deacetylases by romidepsin potently induces Epstein-Barr virus lytic cycle and mediates enhanced cell death with ganciclovir. PMID: 26205347 Ref: Epigenetic silencing of GDF1 disrupts SMAD signaling to reinforce gastric cancer development. PMID: 26212015 Ref: AMPK activator AICAR promotes 5-FU-induced apoptosis in gastric cancer cells. PMID: 26497305 Ref: Overexpressed CISD2 has prognostic value in human gastric cancer and promotes gastric cancer cell proliferation and tumorigenesis via AKT signaling pathway. PMID: 26565812 Ref: GNA13 as a prognostic factor and mediator of gastric cancer progression. PMID: 26735177 Ref: Expression of aurora kinase A correlates with the Wnt-modulator RACGAP1 in gastric cancer. PMID: 26778597 Ref: Increased expression of LncRNA PANDAR predicts a poor prognosis in gastric cancer. PMID: 26898439 Ref: Increased expression of long noncoding RNA TUG1 predicts a poor prognosis of gastric cancer and regulates cell proliferation by epigenetically silencing of p57. PMID: 26913601 Ref: RNA-binding motif protein 47 inhibits Nrf2 activity to suppress tumor growth in lung adenocarcinoma. PMID: 26923328 Ref: The potential of deferasirox as a novel therapeutic modality in gastric cancer. PMID: 26965928 Ref: Ablation of human telomerase reverse transcriptase (hTERT) induces cellular senescence in gastric cancer through a galectin-3 dependent mechanism. PMID: 27494887 Ref: Paris Saponin I Sensitizes Gastric Cancer Cell Lines to Cisplatin via Cell Cycle Arrest and Apoptosis. PMID: 27755523 |
Ref: CDKN1A histone acetylation and gene expression relationship in gastric adenocarcinomas. PMID: 26567008 Ref: miR-340 Inhibits Proliferation and Induces Apoptosis in Gastric Cancer Cell Line SGC-7901, Possibly via the AKT Pathway. PMID: 28057912 Ref: Long noncoding RNA HOXA-AS2 represses P21 and KLF2 expression transcription by binding with EZH2, LSD1 in colorectal cancer. PMID: 28112720 Ref: Long noncoding AGAP2-AS1 is activated by SP1 and promotes cell proliferation and invasion in gastric cancer. PMID: 28209205 Ref: Expression of estrogen receptors and androgen receptor and their clinical significance in gastric cancer. PMID: 28388558 Ref: KLF15 Inhibits Cell Proliferation in Gastric Cancer Cells via Up-Regulating CDKN1A/p21 and CDKN1C/p57 Expression. PMID: 28421457 Ref: Long non-coding RNA PCAT-1 over-expression promotes proliferation and metastasis in gastric cancer cells through regulating CDKN1A. PMID: 28571676 Ref: Prognostic and Predictive Value of p21-activated Kinase 6 Associated Support Vector Machine Classifier in Gastric Cancer Treated by 5-fluorouracil/Oxaliplatin Chemotherapy. PMID: 28687498 Ref: Mutational analysis of driver genes with tumor suppressive and oncogenic roles in gastric cancer. PMID: 28729958 Ref: Diallyl trisulfide induces apoptosis and mitotic arrest in AGS human gastric carcinoma cells through reactive oxygen species-mediated activation of AMP-activated protein kinase. PMID: 28753455 Ref: Hard clam extracts induce atypical apoptosis in human gastric cancer cells. PMID: 28810604 Ref: PANDAR: a pivotal cancer-related long non-coding RNA in human cancers. PMID: 28976505 Ref: Liquiritin induces apoptosis and autophagy in cisplatin (DDP)-resistant gastric cancer cells in vitro and xenograft nude mice in vivo. PMID: 29048624 Ref: Functions of the AP-2alpha gene in activating apoptosis and inhibiting proliferation of gastric cancer cells both in vitro and in vivo. PMID: 29181055 |
Ref: Long noncoding RNA PANDAR blocks CDKN1A gene transcription by competitive interaction with p53 protein in gastric cancer. PMID: 29416011 Ref: Parthenolide facilitates apoptosis and reverses drug-resistance of human gastric carcinoma cells by inhibiting the STAT3 signaling pathway. PMID: 29467878 Ref: Characterization of oncogene suppressor marker expression in patients with submucosal gastric carcinoma. PMID: 29468062 Ref: Melatonin induces the apoptosis and inhibits the proliferation of human gastric cancer cells via blockade of the AKT/MDM2 pathway. PMID: 29484412 Ref: Long non-coding RNA CASC15 regulates gastric cancer cell proliferation, migration and epithelial mesenchymal transition by targeting CDKN1A and ZEB1. PMID: 29489064 Ref: ROS-mediated activation of AMPK plays a critical role in sulforaphane-induced apoptosis and mitotic arrest in AGS human gastric cancer cells. PMID: 29593120 Ref: Long noncoding RNA SNHG6 regulates p21 expression via activation of the JNK pathway and regulation of EZH2 in gastric cancer cells. PMID: 30031062 Ref: MicroRNA181a promotes cell proliferation and inhibits apoptosis in gastric cancer by targeting RASSF1A. PMID: 30106448 Ref: Berberine: A potential adjunct for the treatment of gastrointestinal cancers? PMID: 30125974 Ref: MicroRNA-96 expression induced by low-dose cisplatin or doxorubicin regulates chemosensitivity, cell death and proliferation in gastric cancer SGC7901 cells by targeting FOXO1. PMID: 30128023 Ref: Prognostic value of long noncoding RNAs in gastric cancer: a meta-analysis. PMID: 30147339 Ref: Extracellular acidity enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis via DR5 in gastric cancer cells. PMID: 30181698 Ref: EGR1-mediated transcription of lncRNA-HNF1A-AS1 promotes cell cycle progression in gastric cancer. PMID: 30185552 Ref: Epstein-Barr Virus miR-BART5-3p inhibits p53 expression. PMID: 30209170 |