Primary Site >> Biliary tract Cancer

Gene >> CDKN1A

  • 1999
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  • 2004
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  • 2010
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  • 2018
Ref: Protein expression and genetic alterations of p53 and ras in intrahepatic cholangiocarcinoma.
PMID: 10469215
Ref: Involvement of p38 mitogen-activated protein kinase signaling in transformed growth of a cholangiocarcinoma cell line.
PMID: 11124819
Ref: Reduced p21(WAF1/CIP1) expression is an early event in gallbladder carcinogenesis and is of prognostic significance for patients with carcinomas of the gallbladder.
PMID: 11521218
Ref: Deregulation of G1/S transition is a common event in carcinoma of the ampulla of vater.
PMID: 12239913
Ref: PPARgamma ligands inhibit cholangiocarcinoma cell growth through p53-dependent GADD45 and p21 pathway.
PMID: 12829999
Ref: Cyclooxygenase-2 promotes human cholangiocarcinoma growth: evidence for cyclooxygenase-2-independent mechanism in celecoxib-mediated induction of p21waf1/cip1 and p27kip1 and cell cycle arrest.
PMID: 14973068
Ref: Frequent p16ink4a inactivation is an early and frequent event of intraductal papillary neoplasm of the liver arising in hepatolithiasis.
PMID: 15619210
Ref: Expression of p21 and p27 in gallbladder cancer.
PMID: 17457432
Ref: Expression of p21(Wafl/Cip1), p57(Kip2) and HER2/neu in patients with gallbladder cancer.
PMID: 17595796
Ref: Histone deacetylase inhibitor MS-275 alone or combined with bortezomib or sorafenib exhibits strong antiproliferative action in human cholangiocarcinoma cells.
PMID: 17724801
Ref: Inhibition of histone deacetylase for the treatment of biliary tract cancer: a new effective pharmacological approach.
PMID: 17729398
Ref: 22-oxa-1,25-dihydroxyvitamin D3 efficiently inhibits tumor growth in inoculated mice and primary histoculture of cholangiocarcinoma.
PMID: 20681031
Ref: CIZ1 promoted the growth and migration of gallbladder cancer cells.
PMID: 25427641
Ref: Magnolol inhibits growth of gallbladder cancer cells through the p53 pathway.
PMID: 26250568
Ref: 20(S)-ginsenoside Rg3 promotes senescence and apoptosis in gallbladder cancer cells via the p53 pathway.
PMID: 26309394
Ref: Sirtuin7 has an oncogenic potential via promoting the growth of cholangiocarcinoma cells.
PMID: 29438839
Ref: Epigenetic silencing of tumor suppressor gene CDKN1A by oncogenic long non-coding RNA SNHG1 in cholangiocarcinoma.
PMID: 29970899