Primary Site >> Colorectal Cancer
Gene >> CDK20
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Ref: Colon goblet cells lose proliferative response to TGF alpha as they differentiate. PMID: 7790121 |
Ref: Bromocriptine transcriptionally activates the multidrug resistance gene (pgp2/mdr1b) by a novel pathway. PMID: 9111066 Ref: A variant form of ETS1 induces apoptosis in human colon cancer cells. PMID: 9266972 |
Ref: Disruption of fibronectin binding to the alpha 5 beta 1 integrin stimulates the expression of cyclin-dependent kinases and DNA synthesis through activation of extracellular signal-regulated kinase. PMID: 9430710 Ref: Signal transduction mechanisms in neurotensin-mediated cellular regulation. PMID: 9706144 Ref: Increased constitutive activity of mitogen-activated protein kinase and renaturable 85 kDa kinase in human-colorectal cancer. PMID: 9823970 |
Ref: The p42 variant of ETS1 protein rescues defective Fas-induced apoptosis in colon carcinoma cells. PMID: 10097131 Ref: Expression and activity of mitogen activated protein kinases in human colorectal carcinoma. PMID: 10323886 Ref: Requirement of the MAP kinase cascade for cell cycle progression and differentiation of human intestinal cells. PMID: 10484389 |
Ref: Leptin is a growth factor for colonic epithelial cells. PMID: 11438496 Ref: Epidermal growth factor induces expression of decay-accelerating factor in human colonic cancer cells via the mitogen-activated protein kinase pathway. PMID: 11528371 |
Ref: Influence of epidermal growth factor receptor (EGFR), p53 and intrinsic MAP kinase pathway status of tumour cells on the antiproliferative effect of ZD1839 ("Iressa"). PMID: 11986789 Ref: Perturbation by geraniol of cell membrane permeability and signal transduction pathways in human colon cancer cells. PMID: 12388655 |
Ref: Aberrant expression and activation of the thrombin receptor protease-activated receptor-1 induces cell proliferation and motility in human colon cancer cells. PMID: 12707033 Ref: Raf proteins and cancer: B-Raf is identified as a mutational target. PMID: 12781369 |
Ref: Critical involvement of stress-activated mitogen-activated protein kinases in the regulation of intracellular adhesion molecule-1 in serosal fibroblasts isolated from patients with Crohn's disease. PMID: 15275879 |
Ref: Extracellular cysteine/cystine redox regulates the p44/p42 MAPK pathway by metalloproteinase-dependent epidermal growth factor receptor signaling. PMID: 15746213 Ref: Caspase-1 is a direct target gene of ETS1 and plays a role in ETS1-induced apoptosis. PMID: 16103071 |
Ref: Mitogen-activated protein kinase signaling is activated in prostate tumors but not mediated by B-RAF mutations. PMID: 16413100 Ref: Sphinganine causes early activation of JNK and p38 MAPK and inhibition of AKT activation in HT-29 human colon cancer cells. PMID: 16475687 Ref: Expression of interleukin (IL)-11 and IL-11 receptor in human colorectal adenocarcinoma: IL-11 up-regulation of the invasive and proliferative activity of human colorectal carcinoma cells. PMID: 16964382 |
Ref: Celecoxib decreases expression of the adhesion molecules ICAM-1 and VCAM-1 in a colon cancer cell line (HT29). PMID: 18084318 |
Ref: Chloroquine inhibits colon cancer cell growth in vitro and tumor growth in vivo via induction of apoptosis. PMID: 19194831 |
Ref: Functional characterisation of cell cycle-related kinase (CCRK) in colorectal cancer carcinogenesis. PMID: 20466538 |
Ref: SKLB610: a novel potential inhibitor of vascular endothelial growth factor receptor tyrosine kinases inhibits angiogenesis and tumor growth in vivo. PMID: 21691074 Ref: Inhibition of Rho-associated coiled-coil containing protein kinase enhances the activation of epidermal growth factor receptor in pancreatic cancer cells. PMID: 21722395 |
Ref: p42.3: a promising biomarker for the progression and prognosis of human colorectal cancer. PMID: 23576022 |
Ref: TIF1beta is phosphorylated at serine 473 in colorectal tumor cells through p38 mitogen-activated protein kinase as an oxidative defense mechanism. PMID: 28864417 |
Ref: CCRK is a novel signalling hub exploitable in cancer immunotherapy. PMID: 29360538 |