Primary Site >> Stomach Cancer

Gene >> CDK1

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Ref: Increased expression of p34cdc2 and its kinase activity in human gastric and colonic carcinomas.
PMID: 8416202
Ref: Interleukin 4 regulates G1 cell cycle progression in gastric carcinoma cells.
PMID: 8313369
Ref: The prognostic significance of p34cdc2 and cyclin D1 protein expression in prostate adenocarcinoma.
PMID: 9264360
Ref: Cyclin-dependent kinase inhibitors block proliferation of human gastric cancer cells.
PMID: 9288122
Ref: Prognostic factors in gastric cancer.
PMID: 9758367
Ref: The in vivo effect of bryostatin-1 on paclitaxel-induced tumor growth, mitotic entry, and blood flow.
PMID: 10778982
Ref: Adenovirus-mediated E2F-1 gene transfer induces an apoptotic response in human gastric carcinoma cells that is enhanced by cyclin dependent kinase inhibitors.
PMID: 10851267
Ref: Synthetic retinoid CD437 induces cell-dependent cycle arrest by differential regulation of cell cycle associated proteins.
PMID: 12529993
Ref: Telomerase activity, expression of Bcl-2 and cell cycle regulation in doxorubicin resistant gastric carcinoma cell lines.
PMID: 12579337
Ref: Helicobacter pylori inhibits activity of cdc2 kinase and delays G2/M to G1 progression in gastric adenocarcinoma cell line.
PMID: 12678330
Ref: Flavopiridol enhances the effect of docetaxel in vitro and in vivo in human gastric cancer cells.
PMID: 12813134
Ref: Cyclin-dependent kinase 1 gene expression is associated with poor prognosis in gastric carcinoma.
PMID: 14654553
Ref: BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo.
PMID: 15231674
Ref: [In vitro inhibitory effect of dibenzoxanthene CY-B12 on proliferation of tumor cell lines and its possible mechanisms].
PMID: 16351789
Ref: Effect of pseudolaric acid B on gastric cancer cells: inhibition of proliferation and induction of apoptosis.
PMID: 16437677
Ref: Berberine induces cell cycle arrest and apoptosis in human gastric carcinoma SNU-5 cell line.
PMID: 16440412
Ref: Inhibitory effect of Polo-like kinase 1 depletion on mitosis and apoptosis of gastric cancer cells.
PMID: 16440413
Ref: Gambogic acid-induced G2/M phase cell-cycle arrest via disturbing CDK7-mediated phosphorylation of CDC2/p34 in human gastric carcinoma BGC-823 cells.
PMID: 17012222
Ref: Chromosomal instability by beta-catenin/TCF transcription in APC or beta-catenin mutant cells.
PMID: 17160019
Ref: Cell growth inhibition, G2M cell cycle arrest, and apoptosis induced by the novel compound Alternol in human gastric carcinoma cell line MGC803.
PMID: 17619824
Ref: Prognostic implications of cyclin B1, p34cdc2, p27(Kip1) and p53 expression in gastric cancer.
PMID: 17722244
Ref: Comparative evaluation of C1311 cytotoxic activity and interference with cell cycle progression in a panel of human solid tumour and leukaemia cell lines.
PMID: 17786324
Ref: Anti-proliferative and chemosensitizing effects of luteolin on human gastric cancer AGS cell line.
PMID: 18398671
Ref: Induction of G2/M arrest and apoptosis by water extract of Strychni Semen in human gastric carcinoma AGS cells.
PMID: 18446845
Ref: Activated Akt as an indicator of prognosis in gastric cancer.
PMID: 18841391
Ref: Oroxylin A induces G2/M phase cell-cycle arrest via inhibiting Cdk7-mediated expression of Cdc2/p34 in human gastric carcinoma BGC-823 cells.
PMID: 18957166
Ref: Restoration of XAF1 expression induces apoptosis and inhibits tumor growth in gastric cancer.
PMID: 19358264
Ref: Overexpression of eukaryotic elongation factor eEF2 in gastrointestinal cancers and its involvement in G2/M progression in the cell cycle.
PMID: 19360331
Ref: Ochratoxin A induces G(2) phase arrest in human gastric epithelium GES-1 cells in vitro.
PMID: 20060447
Ref: Simvastatin inhibits cell growth and induces apoptosis and G0/G1 cell cycle arrest in hepatic cancer cells.
PMID: 20878096
Ref: Involvement of MAPK and PI3K signaling pathway in sterigmatocystin-induced G2 phase arrest in human gastric epithelium cells.
PMID: 21287681
Ref: Induction of apoptosis by evodiamine involves both activation of mitotic arrest and mitotic slippage.
PMID: 21887472
Ref: Paris chinensis dioscin induces G2/M cell cycle arrest and apoptosis in human gastric cancer SGC-7901 cells.
PMID: 22110264
Ref: Paris saponin I induces G(2)/M cell cycle arrest and apoptosis in human gastric carcinoma SGC7901 cells.
PMID: 22173496
Ref: Intestinal metabolite compound K of panaxoside inhibits the growth of gastric carcinoma by augmenting apoptosis via Bid-mediated mitochondrial pathway.
PMID: 21323864
Ref: Novel anti-cancer role of naphthazarin in human gastric cancer cells.
PMID: 21904775
Ref: Xanthatin induces G2/M cell cycle arrest and apoptosis in human gastric carcinoma MKN-45 cells.
PMID: 22532019
Ref: Maspin genetically and functionally associates with gastric cancer by regulating cell cycle progression.
PMID: 22962304
Ref: 7-difluoromethoxyl-5,4'-di-n-octylgenistein inhibits growth of gastric cancer cells through downregulating forkhead box M1.
PMID: 22969238
Ref: Revealing the molecular mechanism of gastric cancer marker annexin A4 in cancer cell proliferation using exon arrays.
PMID: 22970268
Ref: Interaction effects between genes involved in the AKT signaling pathway and phytoestrogens in gastric carcinogenesis: a nested case-control study from the Korean Multi-Center Cancer Cohort.
PMID: 23042672
Ref: Silibinin triggers apoptosis and cell-cycle arrest of SGC7901 cells.
PMID: 22619007
Ref: Genistein induces G2/M arrest in gastric cancer cells by increasing the tumor suppressor PTEN expression.
PMID: 24053672
Ref: Anti-tumor activity of the X-linked inhibitor of apoptosis (XIAP) inhibitor embelin in gastric cancer cells.
PMID: 24136460
Ref: Involvement of BID translocation in glycyrrhetinic acid and 11-deoxy glycyrrhetinic acid-induced attenuation of gastric cancer growth.
PMID: 24547973
Ref: Nanostring-based multigene assay to predict recurrence for gastric cancer patients after surgery.
PMID: 24598828
Ref: Antitumor activity of di-n-butyl-(2,6-difluorobenzohydroxamato)tin(IV) against human gastric carcinoma SGC-7901 cells via G2/M cell cycle arrest and cell apoptosis.
PMID: 24643073
Ref: Orostachys japonicus induces apoptosis and cell cycle arrest through the mitochondria-dependent apoptotic pathway in AGS human gastric cancer cells.
PMID: 24789703
Ref: A novel derivative of quinazoline, WYK431 induces G2/M phase arrest and apoptosis in human gastric cancer BGC823 cells through the PI3K/Akt pathway.
PMID: 24859921
Ref: Overexpression of nuclear apoptosis-inducing factor 1 altered the proteomic profile of human gastric cancer cell MKN45 and induced cell cycle arrest at G1/S phase.
PMID: 24926661
Ref: Downregulation of Cdk1 and cyclinB1 expression contributes to oridonin-induced cell cycle arrest at G2/M phase and growth inhibition in SGC-7901 gastric cancer cells.
PMID: 25124639
Ref: Silibinin inhibits proliferation, induces apoptosis and causes cell cycle arrest in human gastric cancer MGC803 cells via STAT3 pathway inhibition.
PMID: 25169527
Ref: Cantharidin induces G2/M phase arrest and apoptosis in human gastric cancer SGC-7901 and BGC-823 cells.
PMID: 25364455
Ref: Alkaloids from beach spider lily (Hymenocallis littoralis) induce apoptosis of HepG-2 cells by the fas-signaling pathway.
PMID: 25422219
Ref: Mad2 and BubR1 modulates tumourigenesis and paclitaxel response in MKN45 gastric cancer cells.
PMID: 25483095
Ref: Tanshinone IIA inhibits gastric carcinoma AGS cells through increasing p-p38, p-JNK and p53 but reducing p-ERK, CDC2 and cyclin B1 expression.
PMID: 25503137
Ref: Kaempferol inhibits gastric cancer tumor growth: An in vitro and in vivo study.
PMID: 25500692
Ref: Targeting heat-shock protein 90 with ganetespib for molecularly targeted therapy of gastric cancer.
PMID: 25590805
Ref: Deoxypodophyllotoxin induces G2/M cell cycle arrest and apoptosis in SGC-7901 cells and inhibits tumor growth in vivo.
PMID: 25608854
Ref: Inhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells.
PMID: 25609923
Ref: Myeloid cell leukemia-1 regulates the cell growth and predicts prognosis in gastric cancer.
PMID: 25672320
Ref: Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer AGS and N
PMID: 25767376
Ref: Identification of potential targets for diallyl disulfide in human gastric cancer MGC-803 cells using proteomics approaches.
PMID: 25812569
Ref: BTG1 expression correlates with pathogenesis, aggressive behaviors and prognosis of gastric cancer: a potential target for gene therapy.
PMID: 26050197
Ref: Honokiol induces cell cycle arrest and apoptosis in human gastric carcinoma MGC-803 cell line.
PMID: 26131123
Ref: Aqueous extracts of Fructus Ligustri Lucide induce gastric carcinoma cell apoptosis and G2/M cycle arrest.
PMID: 26550140
Ref: Novel mechanism of harmaline on inducing G2/M cell cycle arrest and apoptosis by up-regulating Fas/FasL in SGC-7901 cells.
PMID: 26678950
Ref: Activation of nuclear PTEN by inhibition of Notch signaling induces G2/M cell cycle arrest in gastric cancer.
PMID: 25823029
Ref: Chelidonine induces mitotic slippage and apoptotic-like death in SGC-7901 human gastric carcinoma cells.
PMID: 26677104
Ref: [Jaridonin, a new diterpenoid from Isodon rubescens, induces cell cycle arrest in gastric cancer cells through activating ataxia telangiectasia mutated kinase].
PMID: 27087371
Ref: miR-200b induces cell cycle arrest and represses cell growth in esophageal squamous cell carcinoma.
PMID: 27496804
Ref: Menadione induces G2/M arrest in gastric cancer cells by down-regulation of CDC25C and proteasome mediated degradation of CDK1 and cyclin B1.
PMID: 28077999
Ref: Andrographolide Inhibits Proliferation and Metastasis of SGC7901 Gastric Cancer Cells.
PMID: 28194420
Ref: CDKL1 promotes tumor proliferation and invasion in colorectal cancer.
PMID: 28352193
Ref: Anthelmintic drug albendazole arrests human gastric cancer cells at the mitotic phase and induces apoptosis.
PMID: 28352336
Ref: Cell cycle protein Bora serves as a novel poor prognostic factor in multiple adenocarcinomas.
PMID: 28402276
Ref: Synthesis and Antiproliferative Activity of Novel All-Trans-Retinoic Acid-Podophyllotoxin Conjugate towards Human Gastric Cancer Cells.
PMID: 28420180
Ref: pPeOp from Omphalia lapidescens Schroet induces cell cycle arrest and inhibits the migration of MC-4 gastric tumor cells.
PMID: 28693202
Ref: Effects of purified Omphalia lapidescens protein on metastasis, cell cycle, apoptosis and the JAK-STAT signaling pathway in SGC-7901 human gastric cells.
PMID: 29102525
Ref: FPHPB inhibits gastric tumor cell proliferation by inducing G2-M cell cycle arrest.
PMID: 29304495
Ref: Characterization and validation of potential therapeutic targets based on the molecular signature of patient-derived xenografts in gastric cancer.
PMID: 29433585
Ref: Morphologic and Immunohistochemical Appraisal of Primary Gastric Carcinomas.
PMID: 29438113
Ref: [6]-Gingerol enhances the radiosensitivity of gastric cancer via G2/M phase arrest and apoptosis induction.
PMID: 29512739
Ref: Effects of purified Omphalia lapidescens protein on metastasis, cell cycle, apoptosis and the JAK-STAT signaling pathway in SGC-7901 human gastric cells.
PMID: 29541181
Ref: Osthole inhibits gastric cancer cell proliferation through regulation of PI3K/AKT.
PMID: 29590128
Ref: Discovery of an Indirubin Derivative as a Novel c-Met Kinase Inhibitor with in vitro Anti-Tumor Effects.
PMID: 30060294
Ref: Genetically engineered drug rhCNB induces apoptosis and cell cycle arrest in both gastric cancer cells and hepatoma cells.
PMID: 30154649
Ref: LncRNA CASC11 promoted gastric cancer cell proliferation, migration and invasion in vitro by regulating cell cycle pathway.
PMID: 30200804
Ref: [Screening of cell cycle-related genes regulated by KIAA0101 in gastric cancer].
PMID: 30377125