Primary Site >> Colorectal Cancer

Gene >> CDH3

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Ref: Functional loss of E-cadherin and cadherin-11 alleles on chromosome 16q22 in colonic cancer.
PMID: 10398117
Ref: [New oral anticancer drug, TS-1 (S-1)--from bench to clinic].
PMID: 11432358
Ref: Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells.
PMID: 12203117
Ref: [Timeline from discovery of 5-FU to development of an oral anticancer agent S-1 and its drug concept].
PMID: 16897967
Ref: Pilot study of simplified low-dose S-1 plus CPT-11 as first-line chemotherapy for patients with advanced colorectal cancer.
PMID: 17595792
Ref: High intratumoral dihydropyrimidine dehydrogenase mRNA levels in pancreatic cancer associated with a high rate of response to S-1.
PMID: 18309485
Ref: Successful treatment with S-1 plus CPT-11 for lymph node metastasis from colon cancer: report of a case.
PMID: 18383902
Ref: Ectopic expression of P-cadherin correlates with promoter hypomethylation early in colorectal carcinogenesis and enhanced intestinal crypt fission in vivo.
PMID: 18829530
Ref: Whole genome exon arrays identify differential expression of alternatively spliced, cancer-related genes in lung cancer.
PMID: 18927117
Ref: Identification of a novel tumor-associated antigen, cadherin 3/P-cadherin, as a possible target for immunotherapy of pancreatic, gastric, and colorectal cancers.
PMID: 18927288
Ref: Demethylation of the CDH3 gene is frequently detected in advanced colorectal cancer.
PMID: 19528483
Ref: Frequent CDH3 demethylation in advanced gastric carcinoma.
PMID: 19846933
Ref: Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.
PMID: 19915572
Ref: Reversal of gene expression changes in the colorectal normal-adenoma pathway by NS398 selective COX2 inhibitor.
PMID: 20087348
Ref: [Pharmacokinetic study of S-1 for the treatment of peritoneal metastasis from colon cancer--using a mouse peritoneal metastasis model].
PMID: 20841935
Ref: Fine-mapping of colorectal cancer susceptibility loci at 8q23.3, 16q22.1 and 19q13.11: refinement of association signals and use of in silico analysis to suggest functional variation and unexpected candidate target genes.
PMID: 21531788
Ref: In vivo therapeutic effect of CDH3/P-cadherin-targeting radioimmunotherapy.
PMID: 22223257
Ref: Identification of putative immunologic targets for colon cancer prevention based on conserved gene upregulation from preinvasive to malignant lesions.
PMID: 23682078
Ref: Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer.
PMID: 24691442
Ref: Expression changes of cell-cell adhesion-related genes in colorectal tumors.
PMID: 26137091
Ref: Expression Level of Genes Coding for Cell Adhesion Molecules of Cadherin Group in Colorectal Cancer Patients.
PMID: 26167814
Ref: Filtered selection coupled with support vector machines generate a functionally relevant prediction model for colorectal cancer.
PMID: 27330311
Ref: Discovery of novel plasma proteins as biomarkers for the development of incisional hernias after midline incision in patients with colorectal cancer: The ColoCare study.
PMID: 27745870
Ref: P-Cadherin (CDH3) is overexpressed in colorectal tumors and has potential as a serum marker for colorectal cancer monitoring.
PMID: 29142905