Primary Site >> Pancreatic Cancer
Gene >> CDH2
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Ref: The mutant K-ras oncogene causes pancreatic periductal lymphocytic infiltration and gastric mucous neck cell hyperplasia in transgenic mice. PMID: 12727809 |
Ref: Functional screen of the fanconi anemia pathway in cancer cells by Fancd2 immunoblot. PMID: 15107817 Ref: N-cadherin expression and epithelial-mesenchymal transition in pancreatic carcinoma. PMID: 15217949 Ref: Identification of 27 5' CpG islands aberrantly methylated and 13 genes silenced in human pancreatic cancers. PMID: 15467763 |
Ref: Analysis of E-, N-cadherin, alpha-, beta-, and gamma-catenin expression in human pancreatic carcinoma cell lines. PMID: 15714139 |
Ref: Vascular endothelial growth factor receptor-1 activation mediates epithelial to mesenchymal transition in human pancreatic carcinoma cells. PMID: 16397214 Ref: N-cadherin and keratinocyte growth factor receptor mediate the functional interplay between Ki-RASG12V and p53V143A in promoting pancreatic cell migration, invasion, and tissue architecture disruption. PMID: 16705170 Ref: Collagen I promotes metastasis in pancreatic cancer by activating c-Jun NH(2)-terminal kinase 1 and up-regulating N-cadherin expression. PMID: 17178870 |
Ref: STAT3-induced WNT5A signaling loop in embryonic stem cells, adult normal tissues, chronic persistent inflammation, rheumatoid arthritis and cancer (Review). PMID: 17203201 Ref: Association of axon guidance factor semaphorin 3A with poor outcome in pancreatic cancer. PMID: 17631638 |
Ref: ADH-1 suppresses N-cadherin-dependent pancreatic cancer progression. PMID: 17721921 |
Ref: Tumor expression of integrin-linked kinase (ILK) correlates with the expression of the E-cadherin repressor snail: an immunohistochemical study in ductal pancreatic adenocarcinoma. PMID: 20091050 |
Ref: MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition. PMID: 21102519 Ref: Nuclear factor-kappaB-dependent epithelial to mesenchymal transition induced by HIF-1alpha activation in pancreatic cancer cells under hypoxic conditions. PMID: 21887310 Ref: [Regulatory mechanisms of Hedgehog signaling pathway for epithelial-mesenchymal transition in pancreatic cancer cells]. PMID: 22340649 |
Ref: Establishment of a highly migratory subclone reveals that CD133 contributes to migration and invasion through epithelial-mesenchymal transition in pancreatic cancer. PMID: 22109279 Ref: N-cadherin haploinsufficiency increases survival in a mouse model of pancreatic cancer. PMID: 22158044 Ref: Suppression of the epidermal growth factor receptor inhibits epithelial-mesenchymal transition in human pancreatic cancer PANC-1 cells. PMID: 22271412 Ref: The novel monoclonal antibody HPC2 and N-cadherin distinguish pancreatic ductal adenocarcinoma from cholangiocarcinoma. PMID: 22406361 Ref: Role of Cripto-1 during epithelial-to-mesenchymal transition in development and cancer. PMID: 22542493 Ref: Hypoxia inducible factor-1alpha is necessary for invasive phenotype in Vegf-deleted islet cell tumors. PMID: 22768384 Ref: MUC4 potentiates invasion and metastasis of pancreatic cancer cells through stabilization of fibroblast growth factor receptor 1. PMID: 22791819 Ref: The BHLH transcription factor DEC1 plays an important role in the epithelial-mesenchymal transition of pancreatic cancer. PMID: 22825629 Ref: [Experimental study of the function of nuclear factor-kappaB-dependent epithelial to mesenchymal transition in pancreatic cancer cells under hypoxic conditions]. PMID: 22883954 Ref: Naringenin decreases invasiveness and metastasis by inhibiting TGF-beta-induced epithelial to mesenchymal transition in pancreatic cancer cells. PMID: 23300530 |
Ref: Grape seed proanthocyanidins inhibit migration potential of pancreatic cancer cells by promoting mesenchymal-to-epithelial transition and targeting NF-kappaB. PMID: 22902508 Ref: EGCG inhibits growth of human pancreatic tumors orthotopically implanted in Balb C nude mice through modulation of FKHRL1/FOXO3a and neuropilin. PMID: 22971992 Ref: GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft. PMID: 23200667 Ref: Targeting cancer-related inflammation: Chinese herbal medicine inhibits epithelial-to-mesenchymal transition in pancreatic cancer. PMID: 23922983 Ref: Resveratrol inhibits the epithelial-mesenchymal transition of pancreatic cancer cells via suppression of the PI-3K/Akt/NF-kappaB pathway. PMID: 23992306 Ref: Nox4-derived ROS signaling contributes to TGF-beta-induced epithelial-mesenchymal transition in pancreatic cancer cells. PMID: 24123012 Ref: Novel pancreatic cancer cell lines derived from genetically engineered mouse models of spontaneous pancreatic adenocarcinoma: applications in diagnosis and therapy. PMID: 24278292 |
Ref: Overexpression of AIB1 correlates inversely with E-cadherin expression in pancreatic adenocarcinoma and may promote lymph node metastasis. PMID: 23542947 Ref: CUB-domain containing protein 1 represses the epithelial phenotype of pancreatic cancer cells. PMID: 24384474 Ref: Antagonism of microRNA-99a promotes cell invasion and down-regulates E-cadherin expression in pancreatic cancer cells by regulating mammalian target of rapamycin. PMID: 24461517 Ref: CD133 facilitates epithelial-mesenchymal transition through interaction with the ERK pathway in pancreatic cancer metastasis. PMID: 24468059 Ref: Therapeutic targeting of Neu1 sialidase with oseltamivir phosphate (Tamiflu(R)) disables cancer cell survival in human pancreatic cancer with acquired chemoresistance. PMID: 24470763 Ref: MiR-196a promotes pancreatic cancer progression by targeting nuclear factor kappa-B-inhibitor alpha. PMID: 24504166 Ref: MiR-200a inhibits epithelial-mesenchymal transition of pancreatic cancer stem cell. PMID: 24521357 Ref: Effects of the HIF-1alpha and NF-kappaB loop on epithelial-mesenchymal transition and chemoresistance induced by hypoxia in pancreatic cancer cells. PMID: 24535079 Ref: Inflammation and pancreatic cancer: molecular and functional interactions between S100A8, S100A9, NT-S100A8 and TGFbeta1. PMID: 24670043 Ref: The Activation of beta1-integrin by Type I Collagen Coupling with the Hedgehog Pathway Promotes the Epithelial-Mesenchymal Transition in Pancreatic Cancer. PMID: 24720337 Ref: alpha-Mangostin suppresses the viability and epithelial-mesenchymal transition of pancreatic cancer cells by downregulating the PI3K/Akt pathway. PMID: 24812621 Ref: Upregulation of autophagy by hypoxia-inducible factor-1alpha promotes EMT and metastatic ability of CD133+ pancreatic cancer stem-like cells during intermittent hypoxia. PMID: 24994549 Ref: The vitamin D analog, MART-10, represses metastasis potential via downregulation of epithelial-mesenchymal transition in pancreatic cancer cells. PMID: 25149065 Ref: Human equilibrative nucleoside transporter-1 knockdown tunes cellular mechanics through epithelial-mesenchymal transition in pancreatic cancer cells. PMID: 25314577 |
Ref: Transcriptional silencing of ETS-1 abrogates epithelial-mesenchymal transition resulting in reduced motility of pancreatic cancer cells. PMID: 25421630 Ref: Stromal SLIT2 impacts on pancreatic cancer-associated neural remodeling. PMID: 25590802 Ref: Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells. PMID: 25632222 Ref: Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells. PMID: 25632225 Ref: miR-183 induces cell proliferation, migration, and invasion by regulating PDCD4 expression in the SW1990 pancreatic cancer cell line. PMID: 25776494 Ref: S100 calcium-binding protein A6 promotes epithelial-mesenchymal transition through beta-catenin in pancreatic cancer cell line. PMID: 25799022 Ref: Superoxide dismutase promotes the epithelial-mesenchymal transition of pancreatic cancer cells via activation of the H2O2/ERK/NF-kappaB axis. PMID: 25825208 Ref: Suppression of the Epidermal Growth Factor-like Domain 7 and Inhibition of Migration and Epithelial-Mesenchymal Transition in Human Pancreatic Cancer PANC-1 Cells. PMID: 25987088 Ref: Expression of E-cadherin repressors SNAIL, ZEB1 and ZEB2 by tumour and stromal cells influences tumour-budding phenotype and suggests heterogeneity of stromal cells in pancreatic cancer. PMID: 25989272 Ref: miR-33a suppresses the nuclear translocation of beta-catenin to enhance gemcitabine sensitivity in human pancreatic cancer cells. PMID: 26113407 Ref: Anthothecol-encapsulated PLGA nanoparticles inhibit pancreatic cancer stem cell growth by modulating sonic hedgehog pathway. PMID: 26199979 Ref: Therapeutic designed poly (lactic-co-glycolic acid) cylindrical oseltamivir phosphate-loaded implants impede tumor neovascularization, growth and metastasis in mouse model of human pancreatic carcinoma. PMID: 26309402 |
Ref: N-cadherin functions as a growth suppressor in a model of K-ras-induced PanIN. PMID: 26477318 Ref: The canonical Wnt pathway regulates the metastasis-promoting mucin MUC4 in pancreatic ductal adenocarcinoma. PMID: 26526617 Ref: Epitelial-to-mesenchimal transition and invasion are upmodulated by tumor-expressed granzyme B and inhibited by docosahexaenoic acid in human colorectal cancer cells. PMID: 26830472 Ref: Curcumin inhibits hypoxia-induced epithelialmesenchymal transition in pancreatic cancer cells via suppression of the hedgehog signaling pathway. PMID: 27035865 Ref: Hyperglycemia Promotes the Epithelial-Mesenchymal Transition of Pancreatic Cancer via Hydrogen Peroxide. PMID: 27433288 Ref: Interleukin-32alpha inactivates JAK2/STAT3 signaling and reverses interleukin-6-induced epithelial-mesenchymal transition, invasion, and metastasis in pancreatic cancer cells. PMID: 27471397 Ref: CCL21/CCR7 Axis Contributed to CD133+ Pancreatic Cancer Stem-Like Cell Metastasis via EMT and Erk/NF-kappaB Pathway. PMID: 27505247 Ref: Up-regulation of N-cadherin by Collagen I-activated Discoidin Domain Receptor 1 in Pancreatic Cancer Requires the Adaptor Molecule Shc1. PMID: 27605668 Ref: Inhibition of NF-kappa B pathway leads to deregulation of epithelial-mesenchymal transition and neural invasion in pancreatic cancer. PMID: 27775688 Ref: MicroRNA-93 Promotes Epithelial-Mesenchymal Transition of Endometrial Carcinoma Cells. PMID: 27829043 Ref: Leukotriene B4 induces EMT and vimentin expression in PANC-1 pancreatic cancer cells: Involvement of BLT2 via ERK2 activation. PMID: 27914516 |
Ref: Upregulation of MicroRNA-935 Promotes the Malignant Behaviors of Pancreatic Carcinoma PANC-1 Cells via Targeting Inositol Polyphosphate 4-Phosphatase Type I Gene (INPP4A). PMID: 27733216 Ref: Paracrine IL-6 signaling mediates the effects of pancreatic stellate cells on epithelial-mesenchymal transition via Stat3/Nrf2 pathway in pancreatic cancer cells. PMID: 27750041 Ref: Oridonin inhibition and miR200b3p/ZEB1 axis in human pancreatic cancer. PMID: 27878247 Ref: Methyl-CpG-binding domain 3 inhibits epithelial-mesenchymal transition in pancreatic cancer cells via TGF-beta/Smad signalling. PMID: 27898661 Ref: Analysis of the origin of anaplastic pancreatic cancer and the mechanism of its dedifferentiation. PMID: 28064441 Ref: HNRNPA2B1 regulates the epithelial-mesenchymal transition in pancreatic cancer cells through the ERK/snail signalling pathway. PMID: 28077929 Ref: Furin promotes epithelial-mesenchymal transition in pancreatic cancer cells via Hippo-YAP pathway. PMID: 28259973 Ref: The over expression of long non-coding RNA ANRIL promotes epithelial-mesenchymal transition by activating the ATM-E2F1 signaling pathway in pancreatic cancer: An in vivo and in vitro study. PMID: 28344092 Ref: CBX7 negatively regulates migration and invasion in glioma via Wnt/beta-catenin pathway inactivation. PMID: 28388562 Ref: Hypoxia-inducible factor 1alpha participates in hypoxia-induced epithelial-mesenchymal transition via response gene to complement 32. PMID: 28810656 Ref: Galeterone and its analogs inhibit Mnk-eIF4E axis, synergize with gemcitabine, impede pancreatic cancer cell migration, invasion and proliferation and inhibit tumor growth in mice. PMID: 28881737 Ref: CXCR4/Let-7a Axis Regulates Metastasis and Chemoresistance of Pancreatic Cancer Cells Through Targeting HMGA2. PMID: 28954272 Ref: Sanguinarine inhibits pancreatic cancer stem cell characteristics by inducing oxidative stress and suppressing sonic hedgehog-Gli-Nanog pathway. PMID: 28968696 Ref: SET contributes to the epithelial-mesenchymal transition of pancreatic cancer. PMID: 28978088 Ref: Tenascin-C induces migration and invasion through JNK/c-Jun signalling in pancreatic cancer. PMID: 29088796 Ref: Ursodeoxycholic acid suppresses epithelial-mesenchymal transition and cancer stem cell formation by reducing the levels of peroxiredoxin II and reactive oxygen species in pancreatic cancer cells. PMID: 29130098 Ref: Deubiquitinase USP9X promotes cell migration, invasion and inhibits apoptosis of human pancreatic cancer. PMID: 29130109 |
Ref: Pseudolaric Acid B Inhibits Proliferation, Invasion and Epithelial-to-Mesenchymal Transition in Human Pancreatic Cancer Cell. PMID: 29214772 Ref: CUL4B promotes metastasis and proliferation in pancreatic cancer cells by inducing epithelial-mesenchymal transition via the Wnt/beta-catenin signaling pathway. PMID: 29274277 Ref: Luteolin inhibits pancreatitisinduced acinarductal metaplasia, proliferation and epithelialmesenchymal transition of acinar cells. PMID: 29286098 Ref: Notch signaling molecule is involved in the invasion of MiaPaCa2 cells induced by CoCl2 via regulating epithelialmesenchymal transition. PMID: 29393429 Ref: Furin inhibitor D6R suppresses epithelial-mesenchymal transition in SW1990 and PaTu8988 cells via the Hippo-YAP signaling pathway. PMID: 29435056 Ref: Curcumin inhibits superoxide dismutase-induced epithelial-to-mesenchymal transition via the PI3K/Akt/NF-kappaB pathway in pancreatic cancer cells. PMID: 29512729 Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). PMID: 29786110 Ref: Long noncoding RNA PVT1 promotes epithelialmesenchymal transition via the TGFbeta/Smad pathway in pancreatic cancer cells. PMID: 29845201 Ref: Nab-paclitaxel interrupts cancer-stromal interaction through C-X-C motif chemokine 10-mediated interleukin-6 downregulation in vitro. PMID: 29902349 Ref: MicroRNA-30b targets Snail to impede epithelial-mesenchymal transition in pancreatic cancer stem cells. PMID: 29937934 Ref: Overexpression of GP73 promotes cell invasion, migration and metastasis by inducing epithelial-mesenchymal transition in pancreatic cancer. PMID: 30217697 Ref: ROR1 is highly expressed in circulating tumor cells and promotes invasion of pancreatic cancer. PMID: 30272313 Ref: EVI1 expression is associated with aggressive behavior in intrahepatic cholangiocarcinoma. PMID: 30349952 Ref: High expression of WNT7A predicts poor prognosis and promote tumor metastasis in pancreatic ductal adenocarcinoma. PMID: 30361522 |