Primary Site >> Stomach Cancer
Gene >> CDH17
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Ref: [Metastasis related genes and malignancy in human esophageal, gastric and colorectal cancers]. PMID: 8094950 Ref: Molecular mechanism of stomach carcinogenesis. PMID: 8440743 |
Ref: [Genetic characteristics of scirrhous gastric carcinomas]. PMID: 7944479 Ref: A monoclonal antibody identifies a novel GPI-anchored glycoprotein involved in epithelial intercellular adhesion. PMID: 7962185 Ref: E-cadherin gene mutations provide clues to diffuse type gastric carcinomas. PMID: 8033105 Ref: Alterations of the cadherin-catenin cell adhesion system in cancers. PMID: 8983063 |
Ref: Surgical treatment of tumor metastases: general considerations and results. PMID: 7538364 Ref: [Dysfunction of E-cadherin due to mutation of beta-catenin in a scirrhous gastric cancer cell line]. PMID: 7629993 Ref: [Correlation between the intercellular adhesion molecule (E-cadherin) and its associated protein (alpha-catenin) expression and metastasis in human digestive cancers]. PMID: 7629995 Ref: Molecular biology of gastric cancer. PMID: 7676688 Ref: E-cadherin as a tumor (invasion) suppressor gene. PMID: 7748170 Ref: Loss of E-cadherin-dependent cell-cell adhesion due to mutation of the beta-catenin gene in a human cancer cell line, HSC-39. PMID: 7862112 Ref: Expression of e-cadherin, alpha-catenins and Beta-catenins in human gastric carcinomas - correlation with histology and tumor progression. PMID: 21597700 |
Ref: [Genetic alterations in stomach cancer]. PMID: 8692139 Ref: Dominant negative inhibition of the association between beta-catenin and c-erbB-2 by N-terminally deleted beta-catenin suppresses the invasion and metastasis of cancer cells. PMID: 8806677 Ref: Single-cell mutation analysis of tumors from stained histologic slides. PMID: 8973475 Ref: Mutations of p53, E-cadherin, alpha- and beta-catenin genes and tyrosine phosphorylation of beta-catenin in human gastric carcinomas. PMID: 21541555 |
Ref: Abnormal immunoreactivity of the E-cadherin-catenin complex in gastric carcinoma: relationship with patient survival. PMID: 8978342 Ref: Frequent mutation of the E2F-4 cell cycle gene in primary human gastrointestinal tumors. PMID: 9192806 Ref: Efficiency of single-cell polymerase chain reaction from stained histologic slides and integrity of DNA in archival tissue. PMID: 9458389 Ref: Peritoneal dissemination is inhibited by treatment with antibodies against CD44H, beta(1) integrin, and carcinostatic agents in NUGC-4 human gastric cancer cells. PMID: 21533384 |
Ref: H pylori infection is associated with downregulation of E-cadherin, a molecule involved in epithelial cell adhesion and proliferation control. PMID: 9708215 Ref: Mutations of the human E-cadherin (CDH1) gene. PMID: 9744472 Ref: Expression of cadherin-catenin cell adhesion molecules, phosphorylated tyrosine residues and growth factor receptor-tyrosine kinases in gastric cancers. PMID: 9765619 Ref: Dysregulation of the E-cadherin/catenin complex by irreversible mutations in human carcinomas. PMID: 9823469 |
Ref: Germline E-cadherin gene (CDH1) mutations predispose to familial gastric cancer and colorectal cancer. PMID: 10072428 Ref: Identification of eleven novel tumor-associated E-cadherin mutations. Mutations in brief no. 215. Online. PMID: 10094558 Ref: E-cadherin downregulation in cancer: fuel on the fire? PMID: 10203750 Ref: Low frequency of germline E-cadherin mutations in familial and nonfamilial gastric cancer. PMID: 10206317 Ref: Germline mutations of E-cadherin gene in Korean familial gastric cancer patients. PMID: 10319582 Ref: Beta- and gamma-catenin mutations, but not E-cadherin inactivation, underlie T-cell factor/lymphoid enhancer factor transcriptional deregulation in gastric and pancreatic cancer. PMID: 10392898 Ref: Abnormal expression and function of the E-cadherin-catenin complex in gastric carcinoma cell lines. PMID: 10408833 Ref: Tumour-associated E-cadherin mutations alter cellular morphology, decrease cellular adhesion and increase cellular motility. PMID: 10439038 Ref: E-cadherin germline mutations define an inherited cancer syndrome dominated by diffuse gastric cancer. PMID: 10477433 Ref: Distinct methylation pattern and microsatellite instability in sporadic gastric cancer. PMID: 10495421 Ref: The role of the E-cadherin/catenin adhesion complex in the development and progression of cancer. PMID: 10542129 Ref: Up-regulated cytoplasmic expression, with reduced membranous distribution, of the src substrate p120(ctn) in gastric carcinoma. PMID: 10547572 Ref: Disruption of E-cadherin-mediated cell adhesion systems in gastric cancers in young patients. PMID: 10551330 Ref: Familial gastric cancer: overview and guidelines for management. PMID: 10593993 Ref: Reduction in membranous expression of beta-catenin and increased cytoplasmic E-cadherin expression predict poor survival in gastric cancer. PMID: 10604738 Ref: Molecular biology of gastric carcinoma: from laboratory to bedside. PMID: 10634150 Ref: 9th Seah Cheng Siang Memorial Lecture: gastric cancer--where are we now? PMID: 10672411 Ref: The role of the E-cadherin/catenin complex in gastrointestinal cancer. PMID: 10692769 Ref: Cadherin adhesion in the intestinal crypt regulates morphogenesis, mitogenesis, motogenesis, and metaplasia formation. PMID: 10694934 |
Ref: Epidemiology of gastric cancer: an evaluation of available evidence. PMID: 10779225 Ref: The E-cadherin gene (CDH1) variants T340A and L599V in gastric and colorectal cancer patients in Korea. PMID: 10896919 Ref: Regulation of disease-progression genes in human gastric carcinoma cells by interleukin 8. PMID: 10914718 Ref: Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer. PMID: 10973239 Ref: E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice. PMID: 11040191 Ref: Expression patterns of the E-cadherin-catenin cell-cell adhesion complex in gastric cancer. PMID: 11100378 Ref: Molecular characteristics of eight gastric cancer cell lines established in Japan. PMID: 11107048 Ref: Prognostic significance of E-cadherin/catenin complex expression in gastric cancer. PMID: 11194192 Ref: Molecular aspects of invasion and metastasis of stomach cancer. PMID: 11217448 Ref: The use of molecular biology in diagnosis and prognosis of gastric cancer. PMID: 11525306 Ref: Clinical significance of disordered beta-catenin expression pattern in human gastric cancers. PMID: 11984736 |
Ref: Altered expression and mutation of beta-catenin gene in gastric carcinomas and cell lines. PMID: 11241321 Ref: Genetic and epigenetic changes in stomach cancer. PMID: 11243597 Ref: IQGAP1, a negative regulator of cell-cell adhesion, is upregulated by gene amplification at 15q26 in gastric cancer cell lines HSC39 and 40A. PMID: 11289714 Ref: E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma. PMID: 11313896 Ref: Gastric adenocarcinoma: pathomorphology and molecular pathology. PMID: 11315254 Ref: Absence of microsatellite instability and germline mutations of E-cadherin, APC and p53 genes in Japanese familial gastric cancer. PMID: 11399952 Ref: Immunohistochemical evaluation of cadherin and catenin expression in early gastric carcinomas: correlation with clinicopathologic characteristics and Helicobacter pylori infection. PMID: 11408802 Ref: LI-cadherin: a marker of gastric metaplasia and neoplasia. PMID: 11413113 Ref: Concurrent hypermethylation of multiple tumor-related genes in gastric carcinoma and adjacent normal tissues. PMID: 11413518 Ref: [Molecular mechanism of carcinogenesis in gastric cancer: Intercellular molecule cadherin and catenin]. PMID: 11424459 Ref: A new mutation of E-cadherin gene in familial gastric linitis plastica cancer with extra-digestive dissemination. PMID: 11434599 Ref: Germline E-cadherin gene mutations: is prophylactic total gastrectomy indicated? PMID: 11443625 Ref: Different patterns of beta-catenin expression in gastric carcinomas: relationship with clinicopathological parameters and prognostic outcome. PMID: 11493330 Ref: A germline E-cadherin mutation in a family with gastric and colon cancer. PMID: 11562785 Ref: Inactivation of the E-cadherin gene in sporadic diffuse-type gastric cancer. PMID: 11598162 Ref: Prophylactic total gastrectomy for familial gastric cancer. PMID: 11602891 Ref: Establishment of a new scirrhous gastric cancer cell line with loss of heterozygosity at E-cadherin locus. PMID: 11605005 Ref: Multicellular gastric cancer spheroids recapitulate growth pattern and differentiation phenotype of human gastric carcinomas. PMID: 11606498 Ref: Loss of E-cadherin expression in gastric intestinal metaplasia and later stage p53 altered expression in gastric carcinogenesis. PMID: 11665847 Ref: Changes in the E-cadherin-catenin complex expression in early and advanced gastric cancers. PMID: 11684825 Ref: Association of E-cadherin germ-line alterations with prostate cancer. PMID: 11705864 Ref: Alterations of E-cadherin and beta-catenin in gastric cancer. PMID: 11747475 Ref: Molecular mechanisms involved in the pathogenesis of gastric carcinoma: interactions between genetic alterations, cellular phenotype and cancer histotype. PMID: 11813565 Ref: Single amino acid substitutions in conserved extracellular domains of E-cadherin differ in their functional consequences. PMID: 11846558 |
Ref: Global gene expression analysis of gastric cancer by oligonucleotide microarrays. PMID: 11782383 Ref: Genetic and epigenetic alterations of tumor suppressor and tumor-related genes in gastric cancer. PMID: 11813881 Ref: Abnormal expression of E-cadherin and beta-catenin may be a molecular marker of submucosal invasion and lymph node metastasis in early gastric cancer. PMID: 11856141 Ref: Germline mutations in E-cadherin do not explain association of hereditary prostate cancer, gastric cancer and breast cancer. PMID: 11948460 Ref: Screening E-cadherin in gastric cancer families reveals germline mutations only in hereditary diffuse gastric cancer kindred. PMID: 11968083 Ref: Novel germline CDH1 mutations in hereditary diffuse gastric cancer families. PMID: 11968084 Ref: Molecular biology of gastric cancer. PMID: 11979414 Ref: Prophylactic gastrectomy for CDH1 mutation carriers. PMID: 11998610 Ref: E-cadherin mutations and hereditary gastric cancer: prevention by resection? PMID: 12145417 Ref: Promoter methylation status of E-cadherin, hMLH1, and p16 genes in nonneoplastic gastric epithelia. PMID: 12163364 Ref: Epigenetic versus genetic alterations in the inactivation of E-cadherin. PMID: 12191636 Ref: CDH1 c-160a promotor polymorphism is not associated with risk of stomach cancer. PMID: 12209998 Ref: E-cadherin gene variants in gastric cancer families whose probands are diagnosed with diffuse gastric cancer. PMID: 12216071 Ref: Paracrine cyclooxygenase-2-mediated signalling by macrophages promotes tumorigenic progression of intestinal epithelial cells. PMID: 12370807 Ref: CDX2 regulates liver intestine-cadherin expression in normal and malignant colon epithelium and intestinal metaplasia. PMID: 12404231 Ref: Hereditary aspects of gastric cancer. PMID: 12417969 Ref: Expression of E-cadherin and beta-catenin in gastric carcinoma and its correlation with the clinicopathological features and patient survival. PMID: 12439911 Ref: Association of CDH1 haplotypes with susceptibility to sporadic diffuse gastric cancer. PMID: 12444556 Ref: [Relationship between abnormal expression of beta-catenin in gastric carcinoma and survival]. PMID: 12452049 |
Ref: Abnormal expression of E-cadherin, beta-catenin, and c-erbB-2 in advanced gastric cancer: its association with liver metastasis. PMID: 12548420 Ref: Alteration of E-cadherin-mediated adhesion protein is common, but microsatellite instability is uncommon in young age gastric cancers. PMID: 12558744 Ref: Identification and characterization of human SNAIL3 (SNAI3) gene in silico. PMID: 12579345 Ref: Identification of CDH1 germline missense mutations associated with functional inactivation of the E-cadherin protein in young gastric cancer probands. PMID: 12588804 Ref: N-terminal E-cadherin peptides act as decoy receptors for Listeria monocytogenes. PMID: 12595481 Ref: Ile-Leu substitution (I415L) in germline E-cadherin gene (CDH1) in Japanese familial gastric cancer. PMID: 12604719 Ref: Promoter methylation of E-cadherin gene in gastric mucosa associated with Helicobacter pylori infection and in gastric cancer. PMID: 12631658 Ref: Genetic screening for hereditary diffuse gastric cancer. PMID: 12647996 Ref: Preventive gastrectomy in patients with gastric cancer risk due to genetic alterations of the E-cadherin gene defect. PMID: 12690477 Ref: Deregulation of E-cadherin-catenin complex in precancerous lesions of gastric adenocarcinoma. PMID: 12702045 Ref: Cell adhesion-related gene expression by Helicobacter pylori in gastric epithelial AGS cells. PMID: 12757765 Ref: [Studies of promoter methylation status and protein expression of E-cadherin gene in associated progression stages of gastric cancer]. PMID: 12776596 Ref: Molecular mechanisms of carcinogenesis in gastric cancer. PMID: 12790321 Ref: Soluble E-cadherin is an independent pretherapeutic factor for long-term survival in gastric cancer. PMID: 12805328 Ref: Expression of liver-intestine cadherin and its possible interaction with galectin-3 in ductal adenocarcinoma of the pancreas. PMID: 12824888 Ref: Is there a link between environmental factors and a genetic predisposition to cancer? A lesson from a familial cluster of gastric cancers. PMID: 12855270 Ref: Screening E-cadherin germline mutations in Italian patients with familial diffuse gastric cancer: an analysis in the District of Urbino, Region Marche, Central Italy. PMID: 12908778 Ref: A single nucleotide polymorphism in the E-cadherin gene promoter-160 is not associated with risk of Korean gastric cancer. PMID: 12923325 Ref: Expression of beta-catenin and E-cadherin in the adenoma-carcinoma sequence of the stomach. PMID: 12926124 Ref: [Hereditary gastric cancer. Genetics and clinical management]. PMID: 12940100 Ref: The intracellular E-cadherin germline mutation V832 M lacks the ability to mediate cell-cell adhesion and to suppress invasion. PMID: 12944922 Ref: E-cadherin germline missense mutations and cell phenotype: evidence for the independence of cell invasion on the motile capabilities of the cells. PMID: 14500541 Ref: Locoregional alpha-radioimmunotherapy of intraperitoneal tumor cell dissemination using a tumor-specific monoclonal antibody. PMID: 14506190 Ref: The G/A nucleotide change at cDNA position 2494 in the E-cadherin gene (CDH1): analysis in Italian patients. PMID: 14610318 Ref: [Correlation of E-cadherin, beta-catenin and gamma-catenin gene expression with the invasion and metastasis of gastric carcinoma]. PMID: 14625188 Ref: The role of the E-cadherin gene (CDH1) in diffuse gastric cancer susceptibility: from the laboratory to clinical practice. PMID: 14630673 Ref: Familial gastric cancer. PMID: 14762482 |
Ref: Intragenic deletion of CDH1 as the inactivating mechanism of the wild-type allele in an HDGC tumour. PMID: 14661064 Ref: Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers. PMID: 14742272 Ref: Promoter hypermethylation of E-cadherin and its abnormal expression in Epstein-Barr virus-associated gastric carcinoma. PMID: 14750169 Ref: [Expression of beta-catenin and E-cadherin in early gastric cancer: correlation with clinicopathologic parameters]. PMID: 14978364 Ref: Genes and gastric cancer. PMID: 15011894 Ref: Genetic pathways of two types of gastric cancer. PMID: 15055305 Ref: Gene expression profile of gastric carcinoma: identification of genes and tags potentially involved in invasion, metastasis, and carcinogenesis by serial analysis of gene expression. PMID: 15059891 Ref: Geno- and pheno-typic characterization in ten patients with double-primary gastric and colorectal adenocarcinomas. PMID: 15083323 Ref: Prognostic analysis of E-cadherin gene promoter hypermethylation in patients with surgically resected, node-positive, diffuse gastric cancer. PMID: 15102685 Ref: Abnormal expression of E-cadherin in early gastric carcinoma: its relationship with macroscopic growth patterns and catenin alpha and beta. PMID: 15128072 Ref: Search for new biomarkers of gastric cancer through serial analysis of gene expression and its clinical implications. PMID: 15132764 Ref: Effects of c9,t11-conjugated linoleic acid on adhesion of human gastric carcinoma cell line SGC-7901. PMID: 15133841 Ref: Clinical implications of E-cadherin associated hereditary diffuse gastric cancer. PMID: 15138199 Ref: Increased tyrosine kinase activites may lead to the phenotypic differences of gastric cancer cells. PMID: 15161014 Ref: Germline mutations of the E-cadherin(CDH1) and TP53 genes, rather than of RUNX3 and HPP1, contribute to genetic predisposition in German gastric cancer patients. PMID: 15173255 Ref: Overexpression of LI-cadherin in gastric cancer is associated with lymph node metastasis. PMID: 15178443 Ref: Dynamics of cell adhesion and motility in living cells is altered by a single amino acid change in E-cadherin fused to enhanced green fluorescent protein. PMID: 15259055 Ref: E-Cadherin (CDH1) and p53 rather than SMAD4 and Caspase-10 germline mutations contribute to genetic predisposition in Portuguese gastric cancer patients. PMID: 15288293 Ref: Predictive and prognostic role of E-cadherin protein expression in patients with advanced gastric carcinomas treated with palliative chemotherapy. PMID: 15361706 Ref: CDH1 germline mutation in hereditary gastric carcinoma. PMID: 15457549 Ref: [18F]Fluoro-2-deoxy-D-glucose positron emission tomography detects gastric carcinoma in an early stage in an asymptomatic E-cadherin mutation carrier. PMID: 15475432 Ref: Frequent aberrant methylation of the CDH4 gene promoter in human colorectal and gastric cancer. PMID: 15548679 Ref: Genetic screening for familial gastric cancer. PMID: 20233471 Ref: Nuclear pedigree criteria for the identification of individuals suspected to be at risk of an inherited predisposition to gastric cancer. PMID: 20233472 |
Ref: Effect of tumor-associated mutant E-cadherin variants with defects in exons 8 or 9 on matrix metalloproteinase 3. PMID: 15389640 Ref: Intestinal trefoil factor promotes invasion in non-tumorigenic Rat-2 fibroblast cell. PMID: 15680474 Ref: CDX2 co-localizes with liver-intestine cadherin in intestinal metaplasia and adenocarcinoma of the stomach. PMID: 15732140 Ref: CDH1 associated gastric cancer: a report of a family and review of the literature. PMID: 15780560 Ref: Cell death triggered by alpha-emitting 213Bi-immunoconjugates in HSC45-M2 gastric cancer cells is different from apoptotic cell death. PMID: 15791436 Ref: Molecular-pathological prognostic factors of gastric cancer: a review. PMID: 15864715 Ref: Multinuclear giant cell formation is enhanced by down-regulation of Wnt signaling in gastric cancer cell line, AGS. PMID: 15878526 Ref: Gastric cancer: new genetic developments. PMID: 15895459 Ref: New concepts of molecular biology on gastric carcinogenesis. PMID: 16001683 Ref: Clinicopathological significant and prognostic influence of cadherin-17 expression in gastric cancer. PMID: 16044349 Ref: Gastric mucosa alterations in first-degree relatives of gastric cancer patients. PMID: 16080494 Ref: Frequent loss of membranous E-cadherin in gastric cancers: A cross-talk with Wnt in determining the fate of beta-catenin. PMID: 16132582 Ref: Comparative genomics on SNAI1, SNAI2, and SNAI3 orthologs. PMID: 16142376 Ref: Inactivation of ELF/TGF-beta signaling in human gastrointestinal cancer. PMID: 16158060 Ref: [Promoter methylation profile in gastric cancer]. PMID: 16163424 Ref: Fractionated locoregional low-dose radioimmunotherapy improves survival in a mouse model of diffuse-type gastric cancer using a 213Bi-conjugated monoclonal antibody. PMID: 16203804 Ref: [CpG island methylation of E-cadherin gene promoter in gastric carcinoma]. PMID: 16219136 Ref: Regulation of human peptide transporter 1 (PEPT1) in gastric cancer cells by anticancer drugs. PMID: 16253763 Ref: Epithelial-mesenchymal transition in gastric cancer (Review). PMID: 16273224 Ref: Interaction of CagA with Crk plays an important role in Helicobacter pylori-induced loss of gastric epithelial cell adhesion. PMID: 16275761 Ref: [Prophylactic gastric surgery]. PMID: 16292563 Ref: Discrepancy between E-cadherin protein expression and morphology in human gastric carcinoma cells. PMID: 16334807 Ref: Epstein-barr virus-related gastric adenocarcinoma: an early secondary cancer post hemopoietic stem cell transplantation. PMID: 16344071 |
Ref: Early-onset gastric cancers have a different molecular expression profile than conventional gastric cancers. PMID: 16474375 Ref: Alterations of tumor suppressor and tumor-related genes in the development and progression of gastric cancer. PMID: 16482617 Ref: E-cadherin in gastric cancer. PMID: 16482618 Ref: Conversion of cadherin isoforms in cultured human gastric carcinoma cells. PMID: 16521229 Ref: CDH1 gene promoter hypermethylation in gastric cancer: relationship to Goseki grading, microsatellite instability status, and EBV invasion. PMID: 16531765 Ref: Single nucleotide polymorphisms (SNPs) at CDH1 promoter region in familial gastric cancer. PMID: 16555931 Ref: E-cadherin missense mutations, associated with hereditary diffuse gastric cancer (HDGC) syndrome, display distinct invasive behaviors and genetic interactions with the Wnt and Notch pathways in Drosophila epithelia. PMID: 16600987 Ref: Mechanisms inactivating the gene for E-cadherin in sporadic gastric carcinomas. PMID: 16610016 Ref: A review of the genomics of gastric cancer. PMID: 16616344 Ref: Molecular characteristics of differentiated-type gastric carcinoma with distinct mucin phenotype: LI-cadherin is associated with intestinal phenotype. PMID: 16634965 Ref: Effects of Helicobacter pylori eradication on methylation status of E-cadherin gene in noncancerous stomach. PMID: 16707623 Ref: CDH1/E-cadherin germline mutations in early-onset gastric cancer. PMID: 16801346 Ref: Correlation between serum DNA methylation and prognosis in gastric cancer patients. PMID: 16821608 Ref: Disordered beta-catenin expression and E-cadherin/CDH1 promoter methylation in gastric carcinoma. PMID: 16830381 Ref: A novel mutation in the E-cadherin gene in the first family with hereditary diffuse gastric cancer reported in Spain. PMID: 16870389 Ref: Familial gastric cancer - aetiology and pathogenesis. PMID: 16997156 Ref: Familial gastric cancer - clinical management. PMID: 16997157 Ref: [Hereditary diffuse gastric cancer]. PMID: 17075480 Ref: [The inhibitive effects of celecoxib combined with octreotide on the metastasis of human gastric cancer in vivo]. PMID: 17313803 |
Ref: Expression of liver-intestine cadherin and its correlation with lymph node metastasis in gastric cancer: can it predict N stage preoperatively? PMID: 17063305 Ref: Hereditary diffuse gastric cancer and E-cadherin: description of the first germline mutation in an Italian family. PMID: 17126523 Ref: Non-invasive visualisation of the development of peritoneal carcinomatosis and tumour regression after 213Bi-radioimmunotherapy using bioluminescence imaging. PMID: 17206415 Ref: Identification of seven novel germline mutations in the human E-cadherin (CDH1) gene. PMID: 17221870 Ref: Effect of celecoxib on E-cadherin, VEGF, Microvessel density and apoptosis in gastric cancer. PMID: 17224647 Ref: Altered expression of a Li-cadherin in gastric cancer and intestinal metaplasia. PMID: 17226075 Ref: Slug is overexpressed in gastric carcinomas and may act synergistically with SIP1 and Snail in the down-regulation of E-cadherin. PMID: 17299729 Ref: Destabilized adhesion in the gastric proliferative zone and c-Src kinase activation mark the development of early diffuse gastric cancer. PMID: 17363565 Ref: Association of extracellular cleavage of E-cadherin mediated by MMP-7 with HGF-induced in vitro invasion in human stomach cancer cells. PMID: 17396032 Ref: Preemptive total gastrectomy for hereditary gastric cancer. PMID: 17458604 Ref: EGFR regulates RhoA-GTP dependent cell motility in E-cadherin mutant cells. PMID: 17510211 Ref: Up-regulation of gastric cancer cell invasion by Twist is accompanied by N-cadherin and fibronectin expression. PMID: 17512904 Ref: CDH1 truncating mutations in the E-cadherin gene: an indication for total gastrectomy to treat hereditary diffuse gastric cancer. PMID: 17522512 Ref: Single nucleotide polymorphisms in the promoter region of the E-cadherin gene in gastric cancer: case-control study in a young Mexican population. PMID: 17549573 Ref: Aberrant methylation of multiple genes in gastric carcinomas. PMID: 17652530 Ref: Germline E-cadherin mutations in familial lobular breast cancer. PMID: 17660459 Ref: E-cadherin and beta-catenin expression in Epstein-Barr virus-associated gastric carcinoma and their prognostic significance. PMID: 17663505 Ref: Evidence that the V832M E-cadherin germ-line missense mutation does not influence the affinity of alpha -catenin for the cadherin/catenin complex. PMID: 17668349 Ref: 213Bi-induced death of HSC45-M2 gastric cancer cells is characterized by G2 arrest and up-regulation of genes known to prevent apoptosis but induce necrosis and mitotic catastrophe. PMID: 17699730 Ref: E-cadherin gene promoter hypermethylation in H. pylori-induced enlarged fold gastritis. PMID: 17760721 Ref: Pathophysiological role of the activation of p38 mitogen-activated protein kinases in poorly differentiated gastric cancer. PMID: 17803652 Ref: Association between CDH1 haplotypes and gastric cancer risk in a Japanese population. PMID: 17852867 Ref: Epstein-Barr virus, beta-catenin, and E-cadherin in gastric carcinomas. PMID: 17982235 Ref: [Correlation of E-cadherin hypermethylation to tumorigenesis and development of gastric cancer]. PMID: 17991318 Ref: Identification of an intronic single nucleotide polymorphism leading to allele dropout during validation of a CDH1 sequencing assay: implications for designing polymerase chain reaction-based assays. PMID: 18007144 Ref: [Frequent promoter hypermethylation of several tumor suppressor genes in gastric carcinoma and foveolar epithelium]. PMID: 18069630 Ref: High incidence of familial gastric cancer in Tuscany, a region in Italy. PMID: 18185018 Ref: A short guide to hereditary diffuse gastric cancer. PMID: 19725995 |
Ref: New aspects of Helicobacter pylori infection involvement in gastric oncogenesis. PMID: 17720195 Ref: TMPRSS4 promotes invasion, migration and metastasis of human tumor cells by facilitating an epithelial-mesenchymal transition. PMID: 17968309 Ref: The E-cadherin gene polymorphism 160C->A and cancer risk: A HuGE review and meta-analysis of 26 case-control studies. PMID: 17971340 Ref: Endogastric capsule for E-cadherin gene (CDH1) promoter hypermethylation assessment in DNA from gastric juice of diffuse gastric cancer patients. PMID: 17986624 Ref: Li-cadherin is inversely correlated with galectin-3 expression in gastric cancer. PMID: 17999183 Ref: Enhanced activation of epidermal growth factor receptor caused by tumor-derived E-cadherin mutations. PMID: 18245470 Ref: E-cadherin promoter hypermethylation induced by interleukin-1beta treatment or H. pylori infection in human gastric cancer cell lines. PMID: 18249489 Ref: [Gastric cancer: histological type, histogenesis, and gene abnormalities]. PMID: 18281780 Ref: Positive association of up-regulated Cripto-1 and down-regulated E-cadherin with tumour progression and poor prognosis in gastric cancer. PMID: 18312357 Ref: CDH1 gene polymorphisms, smoking, Helicobacter pylori infection and the risk of gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST). PMID: 18342503 Ref: A clinicopathological study on the expression of cadherin-17 and caudal-related homeobox transcription factor (CDX2) in human gastric carcinoma. PMID: 18353622 Ref: Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells. PMID: 18377425 Ref: Risk-reducing total gastrectomy for germline mutations in E-cadherin (CDH1): pathologic findings with clinical implications. PMID: 18391748 Ref: The NMD mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers. PMID: 18427545 Ref: Hereditary diffuse gastric cancer: diagnosis, genetic counseling, and prophylactic total gastrectomy. PMID: 18442100 Ref: A novel diffuse gastric cancer susceptibility variant in E-cadherin (CDH1) intron 2: a case control study in an Italian population. PMID: 18482459 Ref: Key elements of the BMP/SMAD pathway co-localize with CDX2 in intestinal metaplasia and regulate CDX2 expression in human gastric cell lines. PMID: 18498120 Ref: Increased frequency of CpG island methylator phenotype and CDH1 methylation in a gastric cancer high-risk region of china. PMID: 18607505 Ref: E-cadherin gene alterations in gastric cancers in different ethnic populations. PMID: 18646324 Ref: Genetic polymorphisms of the E-cadherin promoter and risk of sporadic gastric carcinoma in Chinese populations. PMID: 18768510 Ref: Mechanisms and sequelae of E-cadherin silencing in hereditary diffuse gastric cancer. PMID: 18788075 Ref: Hereditary diffuse gastric cancer: implications of genetic testing for screening and prophylactic surgery. PMID: 18798546 Ref: Molecular targets and biological modifiers in gastric cancer. PMID: 19013893 |
Ref: E-cadherin deficiency initiates gastric signet-ring cell carcinoma in mice and man. PMID: 19223545 Ref: Transcriptome dissection of gastric cancer: identification of novel diagnostic and therapeutic targets from pathology specimens. PMID: 19261089 Ref: Role of the epithelial-mesenchymal transition regulator Slug in primary human cancers. PMID: 19273255 Ref: Chronic nonsteroidal anti-inflammatory drug (NSAID) use suppresses multiple CpG islands hyper methylation (CIHM) of tumor suppressor genes in the human gastric mucosa. PMID: 19432886 Ref: Secreted LOXL2 is a novel therapeutic target that promotes gastric cancer metastasis via the Src/FAK pathway. PMID: 19625348 Ref: Nature meets nurture: molecular genetics of gastric cancer. PMID: 19657673 Ref: Upregulation of human DNA binding protein A (dbpA) in gastric cancer cells. PMID: 19749785 Ref: [Associations of E-cadherin gene (CDH1) and hereditary gastric cancer in China]. PMID: 19781162 Ref: Postoperative autovaccinotherapy for patients with gastric cancer and expression of some proteins in tumor tissue. PMID: 19783961 Ref: Cyclooxygenase-2 mediated regulation of E-cadherin occurs in conventional but not early-onset gastric cancer cell lines. PMID: 19940363 Ref: Can gastric cancer be prevented? PMID: 20388948 Ref: Clinicopathological significance of E-cadherin, beta-catenin and p53 expression in gastric adenocarinoma. PMID: 21772890 |
Ref: Differential gene expression triggered by highly cytotoxic alpha-emitter-immunoconjugates in gastric cancer cells. PMID: 19139817 Ref: Chronic aspirin use suppresses CDH1 methylation in human gastric mucosa. PMID: 19184424 Ref: Germline mutation of the E-cadherin gene in three sibling cases with advanced gastric cancer: clinical consequences for the other family members. PMID: 19474748 Ref: Familial gastric cancer and Li-Fraumeni syndrome. PMID: 19674071 Ref: Four human breast cancer cell lines with biallelic inactivating alpha-catenin gene mutations. PMID: 19763817 Ref: High expression of atypical protein kinase C lambda/iota in gastric cancer as a prognostic factor for recurrence. PMID: 19774416 Ref: Allele-specific CDH1 downregulation and hereditary diffuse gastric cancer. PMID: 19965908 Ref: Activation of 5-lipoxygenase is required for nicotine mediated epithelial-mesenchymal transition and tumor cell growth. PMID: 20061081 Ref: Advanced cancer with situs inversus totalis associated with KIF3 complex deficiency: report of two cases. PMID: 20107958 Ref: Establishment and characterization of a new hypoxia-resistant cancer cell line, OCUM-12/Hypo, derived from a scirrhous gastric carcinoma. PMID: 20145613 Ref: CpG island promoter methylation (CIHM) status of tumor suppressor genes correlates with morphological appearances of gastric cancer. PMID: 20150642 Ref: Nitric oxide causes anoikis through attenuation of E-cadherin and activation of caspase-3 in human gastric carcinoma AZ-521 cells infected with Mycoplasma hyorhinis. PMID: 20179380 Ref: The clinical significance of vimentin-expressing gastric cancer cells in bone marrow. PMID: 20358301 Ref: Collagen type I regulates beta-catenin tyrosine phosphorylation and nuclear translocation to promote migration and proliferation of gastric carcinoma cells. PMID: 20372837 Ref: Gene expression profiling of metaplastic lineages identifies CDH17 as a prognostic marker in early stage gastric cancer. PMID: 20398667 Ref: Lentiviral-mediated miRNA against liver-intestine cadherin suppresses tumor growth and invasiveness of human gastric cancer. PMID: 20500517 Ref: Methylation status of CDH1 gene in samples of gastric mucous from Brazilian patients with chronic gastritis infected by Helicobacter pylori. PMID: 20520968 Ref: The expression of E-cadherin-catenin complex in patients with advanced gastric cancer: role in formation of metastasis. PMID: 20529814 Ref: Periodic acid-schiff is superior to hematoxylin and eosin for screening prophylactic gastrectomies from CDH1 mutation carriers. PMID: 20534996 Ref: Role of ES cell-expressed Ras (ERas) in tumorigenicity of gastric cancer. PMID: 20566745 Ref: Association of E-cadherin (CDH1) gene polymorphisms and gastric cancer risk. PMID: 20632448 Ref: Promoter polymorphisms and methylation of E-cadherin (CDH1) and KIT in gastric cancer patients from northern Brazil. PMID: 20651373 Ref: [Hereditary gastric cancer]. PMID: 20824432 Ref: Differential interleukin-6/Stat3 signaling as a function of cellular context mediates Ras-induced transformation. PMID: 20929542 Ref: Protein kinase D1 suppresses epithelial-to-mesenchymal transition through phosphorylation of snail. PMID: 20940406 Ref: [Current views of the molecular mechanisms of gastric cancer progression]. PMID: 21086643 Ref: Inhibitory effects of miRNA-200c on chemotherapy-resistance and cell proliferation of gastric cancer SGC7901/DDP cells. PMID: 21114921 Ref: E-cadherin and beta-catenin expression in gastric neoplastic and non-neoplastic lesions--correlations with H. pylori infection. PMID: 21528754 |
Ref: Blockade of proliferation and migration of gastric cancer via targeting CDH17 with an arti fi cial microRNA. PMID: 20393816 Ref: Over-expression of Ephb4 is associated with carcinogenesis of gastric cancer. PMID: 20686847 Ref: Prophylactic total gastrectomy for individuals with germline CDH1 mutation. PMID: 20719348 Ref: Connective tissue growth factor enhances the migration of gastric cancer through downregulation of E-cadherin via the NF-kappaB pathway. PMID: 20946117 Ref: 177Lu-immunotherapy of experimental peritoneal carcinomatosis shows comparable effectiveness to 213Bi-immunotherapy, but causes toxicity not observed with 213Bi. PMID: 21072513 Ref: Genomic and epigenetic profiles of gastric cancer: potential diagnostic and therapeutic applications. PMID: 21191688 Ref: The E-cadherin (CDH1) -160C>A polymorphism associated with gastric cancer among Asians but not Europeans. PMID: 21214416 Ref: Genomic and genetic alterations influence the progression of gastric cancer. PMID: 21253387 Ref: Role of DNA methylation in the development of diffuse-type gastric cancer. PMID: 21273772 Ref: Loss of E-cadherin in mouse gastric epithelial cells induces signet ring-like cells, a possible precursor lesion of diffuse gastric cancer. PMID: 21276134 Ref: Helicobacter pylori induces malignant transformation of gastric epithelial cells in vitro. PMID: 21284736 Ref: Nicotine promotes cell migration through alpha7 nicotinic acetylcholine receptor in gastric cancer cells. PMID: 21347787 Ref: ERM stable knockdown by siRNA reduced in vitro migration and invasion of human SGC-7901 cells. PMID: 21352885 Ref: CDH1 -160C>A gene polymorphism is an ethnicity-dependent risk factor for gastric cancer. PMID: 21570316 Ref: [Pathology and pathobiology of the gastric carcinoma]. PMID: 21634103 Ref: Intrinsic subtypes of gastric cancer, based on gene expression pattern, predict survival and respond differently to chemotherapy. PMID: 21684283 Ref: Gastric cancer stem-like cells possess higher capability of invasion and metastasis in association with a mesenchymal transition phenotype. PMID: 21782323 Ref: Gastric cancer: basic aspects. PMID: 21896084 Ref: Gastrokine 1 functions as a tumor suppressor by inhibition of epithelial-mesenchymal transition in gastric cancers. PMID: 21898090 Ref: Molecular pathology of gastric cancer: research and practice. PMID: 22005013 Ref: miR-27 promotes human gastric cancer cell metastasis by inducing epithelial-to-mesenchymal transition. PMID: 22018270 Ref: Molecular pathology of gastric carcinoma. PMID: 22104201 Ref: Biomarker analysis of cetuximab plus oxaliplatin/leucovorin/5-fluorouracil in first-line metastatic gastric and oesophago-gastric junction cancer: results from a phase II trial of the Arbeitsgemeinschaft Internistische Onkologie (AIO). PMID: 22152101 Ref: Anti-invasive activity of ethanol extracts of Ganoderma lucidum through tightening of tight junctions and inhibition of matrix metalloproteinase activities in human gastric carcinoma cells. PMID: 22196505 Ref: Inhibition of invasion and metastasis of gastric cancer cells through snail targeting artificial microRNA interference. PMID: 22471493 |
Ref: Phosphorylation of the gastric tumor suppressor RUNX3 following H. pylori infection results in its localization to the cytoplasm. PMID: 21567391 Ref: CDH1 promoter polymorphism and stomach cancer susceptibility. PMID: 21625863 Ref: Down-regulation of P-cadherin with PF-03732010 inhibits cell migration and tumor growth in gastric cancer. PMID: 21720740 Ref: Co-expression of hepatocyte growth factor and c-Met predicts peritoneal dissemination established by autocrine hepatocyte growth factor/c-Met signaling in gastric cancer. PMID: 21796631 Ref: Synergistic tumour suppressor activity of E-cadherin and p53 in a conditional mouse model for metastatic diffuse-type gastric cancer. PMID: 21865403 Ref: Pancreatic ductal adenocarcinoma in hereditary diffuse gastric cancer. A case report. PMID: 21992816 Ref: The predictive effect of cadherin-17 on lymph node micrometastasis in pN0 gastric cancer. PMID: 22009269 Ref: Smad3 regulates E-cadherin via miRNA-200 pathway. PMID: 22020340 Ref: Integrated analysis of whole genome exon array and array-comparative genomic hybridization in gastric and colorectal cancer cells. PMID: 22034905 Ref: The combined expression of metaplasia biomarkers predicts the prognosis of gastric cancer. PMID: 22048633 Ref: Overexpression of EphA2 correlates with epithelial-mesenchymal transition-related proteins in gastric cancer and their prognostic importance for postoperative patients. PMID: 22189617 Ref: Role of PCDH10 and its hypermethylation in human gastric cancer. PMID: 22206871 Ref: PCDH17 gene promoter demethylation and cell cycle arrest by genistein in gastric cancer. PMID: 22207556 Ref: Frequency of CDH1 germline mutations in gastric carcinoma coming from high- and low-risk areas: metanalysis and systematic review of the literature. PMID: 22225527 Ref: Relevance of MET activation and genetic alterations of KRAS and E-cadherin for cetuximab sensitivity of gastric cancer cell lines. PMID: 22290393 Ref: Transcriptional regulation of miR-196b by ETS2 in gastric cancer cells. PMID: 22298639 Ref: MicroRNA-200b regulates cell proliferation, invasion, and migration by directly targeting ZEB2 in gastric carcinoma. PMID: 22311119 Ref: Regulation of glycogen synthase kinase-3 by thymosin beta-4 is associated with gastric cancer cell migration. PMID: 22328534 Ref: ZEB2 promotes the metastasis of gastric cancer and modulates epithelial mesenchymal transition of gastric cancer cells. PMID: 22350782 Ref: Upregulation and secretion of kallikrein-related peptidase 6 (KLK6) in gastric cancer. PMID: 22373580 Ref: IQGAP2, A candidate tumour suppressor of prostate tumorigenesis. PMID: 22406297 Ref: Kruppel-like factor 4 negatively regulates beta-catenin expression and inhibits the proliferation, invasion and metastasis of gastric cancer. PMID: 22407433 Ref: Gastric tumor development in Smad3-deficient mice initiates from forestomach/glandular transition zone along the lesser curvature. PMID: 22411066 Ref: Helicobacter pylori induces promoter methylation of E-cadherin via interleukin-1beta activation of nitric oxide production in gastric cancer cells. PMID: 22415887 Ref: Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. PMID: 22484628 Ref: Association between p16, hMLH1 and E-cadherin promoter hypermethylation and intake of local hot salted tea and sun-dried foods in Kashmiris with gastric tumors. PMID: 22502664 Ref: CDH1 gene polymorphisms, plasma CDH1 levels and risk of gastric cancer in a Chinese population. PMID: 22535324 Ref: Familial gastric cancer and germline mutations of E-cadherin. PMID: 22595728 Ref: The role of human peritoneal mesothelial cells in the fibrosis and progression of gastric cancer. PMID: 22614335 Ref: Liver-intestine cadherin induction by epidermal growth factor receptor is associated with intestinal differentiation of gastric cancer. PMID: 22676223 Ref: Transcription initiation arising from E-cadherin/CDH1 intron2: a novel protein isoform that increases gastric cancer cell invasion and angiogenesis. PMID: 22752307 Ref: Anti-proliferation and anti-invasion effects of diosgenin on gastric cancer BGC-823 cells with HIF-1alpha shRNAs. PMID: 22754381 Ref: Knockdown of liver-intestine cadherin decreases BGC823 cell invasiveness and metastasis in vivo. PMID: 22791949 Ref: N-myc downstream regulated gene 1 (NDRG1) promotes metastasis of human scirrhous gastric cancer cells through epithelial mesenchymal transition. PMID: 22844455 Ref: Genetic testing by cancer site: stomach. PMID: 22846738 Ref: [Hereditary diffuse gastric cancer]. PMID: 22920204 Ref: Epstein-barr virus infected gastric adenocarcinoma expresses latent and lytic viral transcripts and has a distinct human gene expression profile. PMID: 22929309 Ref: Frequent silencing of protocadherin 8 by promoter methylation, a candidate tumor suppressor for human gastric cancer. PMID: 22941331 Ref: Significance of preoperative tissue levels of vascular-endothelial cadherin, liver-intestine cadherin and vascular endothelial growth factor in gastric cancer. PMID: 23089909 Ref: Caveolin-1, E-cadherin and beta-catenin in Gastric Carcinoma, Precancerous Tissues and Chronic Non-atrophic Gastritis. PMID: 23359759 |
Ref: The molecular mechanism of microRNA-145 to suppress invasion-metastasis cascade in gastric cancer. PMID: 22370644 Ref: Establishment and characterization of novel gastric signet-ring cell and non signet-ring cell poorly differentiated adenocarcinoma cell lines with low and high malignant potential. PMID: 22450770 Ref: A novel CDH1 germline missense mutation in a sporadic gastric cancer patient in north-east of Italy. PMID: 22543498 Ref: MicroRNA-7 functions as an anti-metastatic microRNA in gastric cancer by targeting insulin-like growth factor-1 receptor. PMID: 22614005 Ref: Hereditary diffuse gastric cancer: a family diagnosis and treatment. PMID: 22723466 Ref: C-terminal tensin-like gene functions as an oncogene and promotes cell motility in pancreatic cancer. PMID: 22750970 Ref: Heat shock protein 27 expression is inversely correlated with atrophic gastritis and intraepithelial neoplasia. PMID: 22886594 Ref: Epigenetic modulation by methionine deficiency attenuates the potential for gastric cancer cell dissemination. PMID: 22948834 Ref: Expression of serum response factor in gastric carcinoma and its molecular mechanisms involved in the regulation of the invasion and migration of SGC-7901 cells. PMID: 23134219 Ref: An alpha-E-catenin (CTNNA1) mutation in hereditary diffuse gastric cancer. PMID: 23208944 Ref: Searching for E-cadherin gene mutations in early onset diffuse gastric cancer and hereditary diffuse gastric cancer in Korean patients. PMID: 23264079 Ref: Cadherin-17 induces tumorigenesis and lymphatic metastasis in gastric cancer through activation of NFkappaB signaling pathway. PMID: 23298905 Ref: Human metastable epiallele candidates link to common disorders. PMID: 23321599 Ref: STAT3 interacts with Skp2/p27/p21 pathway to regulate the motility and invasion of gastric cancer cells. PMID: 23333463 Ref: Somatic mutations and deletions of the E-cadherin gene predict poor survival of patients with gastric cancer. PMID: 23341533 Ref: [E-cadherin expression and CDH1 promoter methylation in sporadic and hereditary gastric cancer]. PMID: 23353171 Ref: Recombinant Erdr1 suppresses the migration and invasion ability of human gastric cancer cells, SNU-216, through the JNK pathway. PMID: 23370368 Ref: Downregulated microRNA-200a promotes EMT and tumor growth through the wnt/beta-catenin pathway by targeting the E-cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma. PMID: 23381389 Ref: A synergistic interaction between transcription factors nuclear factor-kappaB and signal transducers and activators of transcription 3 promotes gastric cancer cell migration and invasion. PMID: 23402362 Ref: Novel CDH1 germline mutations identified in Chinese gastric cancer patients. PMID: 23431106 Ref: Mutation screen and RNA analysis disclose the changed splicing of the E-cadherin transcription in gastric cancer. PMID: 23435907 Ref: E-cadherin alterations in hereditary disorders with emphasis on hereditary diffuse gastric cancer. PMID: 23481202 Ref: KLF8 involves in TGF-beta-induced EMT and promotes invasion and migration in gastric cancer cells. PMID: 23504025 Ref: Potential advantages of CUDC-101, a multitargeted HDAC, EGFR, and HER2 inhibitor, in treating drug resistance and preventing cancer cell migration and invasion. PMID: 23536719 Ref: Effects of Helicobacter pylori infection on gastric parietal cells and E-cadherin in Mongolian gerbils. PMID: 23545479 Ref: Targeting CDH17 suppresses tumor progression in gastric cancer by downregulating Wnt/beta-catenin signaling. PMID: 23554857 Ref: Molecular and survival differences between familial and sporadic gastric cancers. PMID: 23555086 Ref: Helicobacter pylori-induced alteration of epithelial cell signaling and polarity: a possible mechanism of gastric carcinoma etiology and disparity. PMID: 23629919 Ref: LMP1-induced cell death may contribute to the emergency of its oncogenic property. PMID: 23637765 Ref: E-cadherin and adherens-junctions stability in gastric carcinoma: functional implications of glycosyltransferases involving N-glycan branching biosynthesis, N-acetylglucosaminyltransferases III and V. PMID: 23671930 Ref: MAWBP and MAWD inhibit proliferation and invasion in gastric cancer. PMID: 23687415 Ref: Integrin-linked kinase silencing induces a S/G2/M phases cell cycle slowing and modulates metastasis-related genes in SGC7901 human gastric carcinoma cells. PMID: 23748822 Ref: Laparoscopic prophylactic total gastrectomy with linear stapler side-to-side esophagojejunal anastomosis for hereditary diffuse gastric cancer syndrome in 2 siblings. PMID: 23752020 Ref: Targeted delivery of miR-200c/DOC to inhibit cancer stem cells and cancer cells by the gelatinases-stimuli nanoparticles. PMID: 23806972 Ref: AC1MMYR2, an inhibitor of dicer-mediated biogenesis of Oncomir miR-21, reverses epithelial-mesenchymal transition and suppresses tumor growth and progression. PMID: 23811941 Ref: Honokiol thwarts gastric tumor growth and peritoneal dissemination by inhibiting Tpl2 in an orthotopic model. PMID: 23828905 Ref: Pyruvate kinase M2 plays a dual role on regulation of the EGF/EGFR signaling via E-cadherin-dependent manner in gastric cancer cells. PMID: 23840737 Ref: microRNA-148a suppresses human gastric cancer cell metastasis by reversing epithelial-to-mesenchymal transition. PMID: 23873106 Ref: [CD133 promotes the invasion and metastasis of gastric cancer via epithelial-mesenchymal transition]. PMID: 23888452 Ref: Helicobacter pylori-Induced Chronic Gastritis and Assessing Risks for Gastric Cancer. PMID: 23983680 Ref: Milky spot macrophages remodeled by gastric cancer cells promote peritoneal mesothelial cell injury. PMID: 23994334 Ref: [Effect of RNA interference inhibition to expression of CD133 on tumor cell biological characteristics in KATO-III CD133(+) cells of human gastric cancer]. PMID: 24062002 Ref: CD14 regulates gastric cancer cell epithelialmesenchymal transition and invasion in vitro. PMID: 24064911 Ref: The utility of immunohistochemistry for providing genetic information on tumors. PMID: 24065374 Ref: Interaction between cyclooxygenase-2, Snail, and E-cadherin in gastric cancer cells. PMID: 24115825 Ref: [Effects of inhibition of Hedgehog signaling pathway for transforming growth factor-beta-induced epithelial-mesenchymal transition]. PMID: 24169291 Ref: Identification and characterization of CDH1 germline variants in sporadic gastric cancer patients and in individuals at risk of gastric cancer. PMID: 24204729 Ref: CCR5 Antagonism by Maraviroc Reduces the Potential for Gastric Cancer Cell Dissemination. PMID: 24466382 Ref: Association among lifestyle, clinical examination, polymorphisms in CDH1 gene and Traditional Chinese Medicine syndrome differentiation of gastric cancer. PMID: 24660577 |
Ref: Role of hMLH1 and E-cadherin promoter methylation in gastric cancer progression. PMID: 24022108 Ref: Caveolin-1 promotes gastric cancer progression by up-regulating epithelial to mesenchymal transition by crosstalk of signalling mechanisms under hypoxic condition. PMID: 24070739 Ref: Significance and prognostic value of Gli-1 and Snail/E-cadherin expression in progressive gastric cancer. PMID: 24081672 Ref: Expression of APC, beta-catenin and E-cadherin in Tunisian patients with gastric adenocarcinoma: clinical significance. PMID: 24197976 Ref: Epithelial-mesenchymal transition in human gastric cancer cell lines induced by TNF-alpha-inducing protein of Helicobacter pylori. PMID: 24249671 Ref: SALL4, a novel marker for human gastric carcinogenesis and metastasis. PMID: 24276240 Ref: Reduced expression of the chromatin remodeling gene ARID1A enhances gastric cancer cell migration and invasion via downregulation of E-cadherin transcription. PMID: 24293408 Ref: DNAJB4 molecular chaperone distinguishes WT from mutant E-cadherin, determining their fate in vitro and in vivo. PMID: 24293545 Ref: CD24 mediates gastric carcinogenesis and promotes gastric cancer progression via STAT3 activation. PMID: 24327257 Ref: Transforming growth factor-beta1 signaling blockade attenuates gastric cancer cell-induced peritoneal mesothelial cell fibrosis and alleviates peritoneal dissemination both in vitro and in vivo. PMID: 24347485 Ref: Integrated microRNA network analyses identify a poor-prognosis subtype of gastric cancer characterized by the miR-200 family. PMID: 24352645 Ref: Rescue of wild-type E-cadherin expression from nonsense-mutated cancer cells by a suppressor-tRNA. PMID: 24424122 Ref: Epithelial-to-mesenchymal transition predicts prognosis in clinical gastric cancer. PMID: 24453058 Ref: Targeting cadherin-17 inactivates Ras/Raf/MEK/ERK signaling and inhibits cell proliferation in gastric cancer. PMID: 24465527 Ref: Complementary molecular approaches reveal heterogeneous CDH1 germline defects in Italian patients with hereditary diffuse gastric cancer (HDGC) syndrome. PMID: 24493355 Ref: Expression of the E-cadherin/beta-catenin/tcf-4 pathway in gastric diseases with relation to Helicobacter pylori infection: clinical and pathological implications. PMID: 24528029 Ref: CDH1 polymorphisms and haplotypes in sporadic diffuse and intestinal gastric cancer: a case-control study based on direct sequencing analysis. PMID: 24684952 Ref: Genomic profile analysis of diffuse-type gastric cancers. PMID: 24690483 Ref: RhoGDI2 promotes epithelial-mesenchymal transition via induction of Snail in gastric cancer cells. PMID: 24721928 Ref: Down-regulation of FoxM1 leads to the inhibition of the epithelial-mesenchymal transition in gastric cancer cells. PMID: 24726291 Ref: An updated review of gastric cancer in the next-generation sequencing era: insights from bench to bedside and vice versa. PMID: 24744582 Ref: Down-regulation of WAVE2, WASP family verprolin-homologous protein 2, in gastric cancer indicates lymph node metastasis and cell migration. PMID: 24778020 Ref: Cooperativity of E-cadherin and Smad4 loss to promote diffuse-type gastric adenocarcinoma and metastasis. PMID: 24784840 Ref: p16 Methylation is associated with chemosensitivity to fluorouracil in patients with advanced gastric cancer. PMID: 24816738 Ref: Role of epithelial-mesenchymal transition in gastric cancer initiation and progression. PMID: 24833870 Ref: Normal fibroblasts induce E-cadherin loss and increase lymph node metastasis in gastric cancer. PMID: 24845259 Ref: TGF-beta1-induced expression of Id-1 is associated with tumor progression in gastric cancer. PMID: 24861919 Ref: Roles of E-cadherin (CDH1) genetic variations in cancer risk: a meta-analysis. PMID: 24870781 Ref: Aquaporin 3 promotes epithelial-mesenchymal transition in gastric cancer. PMID: 24887009 Ref: Epidermal growth factor-like domain-containing protein 7 (EGFL7) enhances EGF receptor-AKT signaling, epithelial-mesenchymal transition, and metastasis of gastric cancer cells. PMID: 24945379 Ref: NDRG1 expression is related to the progression and prognosis of gastric cancer patients through modulating proliferation, invasion and cell cycle of gastric cancer cells. PMID: 24985974 Ref: Study on the Biological Characteristics of CD133 (+) Cells Interfered by RNA Interference in Gastric Cancer. PMID: 25006468 Ref: Helicobacter pylori CagA promotes Snail-mediated epithelial-mesenchymal transition by reducing GSK-3 activity. PMID: 25055241 Ref: SRF expedites metastasis and modulates the epithelial to mesenchymal transition by regulating miR-199a-5p expression in human gastric cancer. PMID: 25080937 Ref: Hereditary diffuse gastric cancer associated with E-cadherin germline mutation: a case report. PMID: 25089230 Ref: Baicalein inhibits migration and invasion of gastric cancer cells through suppression of the TGF-beta signaling pathway. PMID: 25109410 Ref: E-cadherin and gastric cancer: cause, consequence, and applications. PMID: 25184143 Ref: Presymptomatic identification of CDH1 germline mutation in a healthy korean individual with family history of gastric cancer. PMID: 25187893 Ref: De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells. PMID: 25216525 Ref: Thrombin conducts epithelialmesenchymal transition via proteaseactivated receptor1 in human gastric cancer. PMID: 25231630 Ref: Trichostatin A induces mesenchymal-like morphological change and gene expression but inhibits migration and colony formation in human cancer cells. PMID: 25269990 Ref: Meta-analysis: E-cadherin immunoexpression as a potential prognosis biomarker related to gastric cancer metastasis in Asian patients. PMID: 25317805 Ref: E-cadherin germline mutation carriers: clinical management and genetic implications. PMID: 25332147 Ref: Association of genetic variants in and promoter hypermethylation of CDH1 with gastric cancer: a meta-analysis. PMID: 25340495 Ref: Germline mutations in MAP3K6 are associated with familial gastric cancer. PMID: 25340522 Ref: Research on the efficacy of Celastrus Orbiculatus in suppressing TGF-beta1-induced epithelial-mesenchymal transition by inhibiting HSP27 and TNF-alpha-induced NF-kappa B/Snail signaling pathway in human gastric adenocarcinoma. PMID: 25370696 Ref: WAVE3 promotes epithelial-mesenchymal transition of gastric cancer through upregulation of Snail. PMID: 25378074 Ref: CEACAM6 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition via PI3K/AKT signaling pathway. PMID: 25398131 Ref: Anti-tumor efficacy of fulvestrant in estrogen receptor positive gastric cancer. PMID: 25534230 Ref: [Effect of miR-92b on migration, adhesion and invasion of human gastric cancer cell line SGC7901]. PMID: 25537895 Ref: Inhibiting Helicobacter pylori HtrA protease by addressing a computationally predicted allosteric ligand binding site. PMID: 26819700 |
Ref: Peroxisome proliferator-activated receptor gamma upregulates galectin-9 and predicts prognosis in intestinal-type gastric cancer. PMID: 24976296 Ref: PRRX1 promotes epithelial-mesenchymal transition through the Wnt/beta-catenin pathway in gastric cancer. PMID: 25428393 Ref: Bone morphogenetic protein 2 mediates epithelial-mesenchymal transition via AKT and ERK signaling pathways in gastric cancer. PMID: 25448881 Ref: The downregulation of miR-200c/141 promotes ZEB1/2 expression and gastric cancer progression. PMID: 25502084 Ref: CCR7 pathway induces epithelial-mesenchymal transition through up-regulation of Snail signaling in gastric cancer. PMID: 25572817 Ref: Exome sequencing reveals three novel candidate predisposition genes for diffuse gastric cancer. PMID: 25576241 Ref: Current status of management of malignant disease: current management of gastric cancer. PMID: 25591828 Ref: Lack of association between the CDH1 polymorphism and gastric cancer susceptibility: a meta-analysis. PMID: 25599647 Ref: Helicobacter pylori bacteria alter the p53 stress response via ERK-HDM2 pathway. PMID: 25605238 Ref: [E-cadherin expression and CDH1 promoter methylation in sporadic and hereditary gastric cancer]. PMID: 25613626 Ref: Inactivation of the phosphatidylinositol 3-kinase/Akt pathway is involved in BMP9-mediated tumor-suppressive effects in gastric cancer cells. PMID: 25640278 Ref: [Experimental study of human bone marrow mesenchymal stem cells on regulating the biological characteristics of gastric cancer cells]. PMID: 25656126 Ref: Thermo-chemotherapy Induced miR-218 upregulation inhibits the invasion of gastric cancer via targeting Gli2 and E-cadherin. PMID: 25694126 Ref: Antimetastatic effects of Celastrus orbiculatus on human gastric adenocarcinoma by inhibiting epithelial-mesenchymal transition and NF-kappaB/snail signaling pathway. PMID: 25722220 Ref: Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer AGS and N PMID: 25767376 Ref: Synthetic Lethal Screens Identify Vulnerabilities in GPCR Signaling and Cytoskeletal Organization in E-Cadherin-Deficient Cells. PMID: 25777964 Ref: Helicobacter pylori-induced epithelial-mesenchymal transition, a potential role of gastric cancer initiation and an emergence of stem cells. PMID: 25784376 Ref: From molecular classification to targeted therapeutics: the changing face of systemic therapy in metastatic gastroesophageal cancer. PMID: 25784931 Ref: Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNFalpha-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction. PMID: 25785838 Ref: The Lauren classification highlights the role of epithelial-to-mesenchymal transition in gastric carcinogenesis: an immunohistochemistry study of the STAT3 and adhesion molecules expression. PMID: 25822437 Ref: Zipper-interacting protein kinase promotes epithelial-mesenchymal transition, invasion and metastasis through AKT and NF-kB signaling and is associated with metastasis and poor prognosis in gastric cancer patients. PMID: 25831050 Ref: Association between cadherin-17 expression and pathological characteristics of gastric cancer: a meta-analysis. PMID: 25834338 Ref: TMEM16A overexpression contributes to tumor invasion and poor prognosis of human gastric cancer through TGF-beta signaling. PMID: 25839162 Ref: High-mobility-group A2 overexpression provokes a poor prognosis of gastric cancer through the epithelial-mesenchymal transition. PMID: 25845850 Ref: A study of RUNX3, E-cadherin and beta-catenin in CagA-positive Helicobacter pylori associated chronic gastritis in Saudi patients. PMID: 25967717 Ref: Histone demethylase RBP2 promotes malignant progression of gastric cancer through TGF-beta1-(p-Smad3)-RBP2-E-cadherin-Smad3 feedback circuit. PMID: 25974964 Ref: Association between human papillomavirus and Epstein - Barr virus DNA and gene promoter methylation of RB1 and CDH1 in the cervical lesions: a transversal study. PMID: 26032781 Ref: Clinicopathologic and molecular characteristics of gastric cancer showing gastric and intestinal mucin phenotype. PMID: 26033320 Ref: Epigenetically downregulated Semaphorin 3E contributes to gastric cancer. PMID: 26036259 Ref: Myeloid cell leukemia-1 promotes epithelial-mesenchymal transition of human gastric cancer cells. PMID: 26058661 Ref: Resveratrol inhibits the hedgehog signaling pathway and epithelial-mesenchymal transition and suppresses gastric cancer invasion and metastasis. PMID: 26137075 Ref: Hereditary Diffuse Gastric Cancer Syndrome: CDH1 Mutations and Beyond. PMID: 26182300 Ref: E-cadherin-defective gastric cancer cells depend on Laminin to survive and invade. PMID: 26246502 Ref: Mitogen-activated protein kinase activator with WD40 repeats (MAWD) and MAWD-binding protein induce cell differentiation in gastric cancer. PMID: 26373288 Ref: Correlation of cadherin-17 protein expression with clinicopathological features and prognosis of patients with sporadic gastric cancer. PMID: 26421870 Ref: Effect of BRMS1 expression on proliferation, migration and adhesion of mouse forestomach carcinoma. PMID: 26433658 Ref: Arsenic sulfide inhibits cell migration and invasion of gastric cancer in vitro and in vivo. PMID: 26487802 Ref: Tumorigenic hybrids between mesenchymal stem cells and gastric cancer cells enhanced cancer proliferation, migration and stemness. PMID: 26498753 Ref: FAT4 functions as a tumour suppressor in gastric cancer by modulating Wnt/beta-catenin signalling. PMID: 26633557 Ref: Epithelial-mesenchymal transition in gastric cancer. PMID: 26807164 Ref: EZH2 Mediates the Regulation of S100A4 on E-cadherin Expression and the Proliferation, Migration of Gastric Cancer Cells. PMID: 26897964 |
Ref: DIXDC1 activates the Wnt signaling pathway and promotes gastric cancer cell invasion and metastasis. PMID: 25648220 Ref: Osteopontin, E-cadherin, and beta-catenin expression as prognostic biomarkers in patients with radically resected gastric cancer. PMID: 25862567 Ref: Preventing E-cadherin aberrant N-glycosylation at Asn-554 improves its critical function in gastric cancer. PMID: 26189796 Ref: CCL18 promotes the invasion and migration of gastric cancer cells via ERK1/2/NF-kappaB signaling pathway. PMID: 26242263 Ref: Phase II trial of dacomitinib in patients with HER2-positive gastric cancer. PMID: 26581547 Ref: Correlations of fascin-1 and cadherin-17 protein expression with clinicopathologic features and prognosis of patients with gastric cancer. PMID: 26743780 Ref: C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of Phosphoinositide 3-Kinase Subunits. PMID: 26855187 Ref: Resistance to the c-Met inhibitor KRC-108 induces the epithelial transition of gastric cancer cells. PMID: 26893681 Ref: Comprehensive molecular portrait using next generation sequencing of resected intestinal-type gastric cancer patients dichotomized according to prognosis. PMID: 26961069 Ref: Phosphatase of regenerating liver-3 inhibits invasiveness and proliferation in non-small cell lung cancer by regulating the epithelial-mesenchymal transition. PMID: 26967563 Ref: Fibroblasts induced epithelial to mesenchymal transition of tumor cells and their extra circulation traveling behavior. PMID: 26968903 Ref: DDR2 Induces Gastric Cancer Cell Activities via Activating mTORC2 Signaling and Is Associated with Clinicopathological Characteristics of Gastric Cancer. PMID: 27010547 Ref: MicroRNA-421 regulated by HIF-1alpha promotes metastasis, inhibits apoptosis, and induces cisplatin resistance by targeting E-cadherin and caspase-3 in gastric cancer. PMID: 27016414 Ref: Gastrointestinal Factor GDDR Attenuates Epithelial-Mesenchymal Transition in Gastric Cancer via Inhibiting AKT Signal. PMID: 27017226 Ref: Gelsolin-mediated activation of PI3K/Akt pathway is crucial for hepatocyte growth factor-induced cell scattering in gastric carcinoma. PMID: 27058427 Ref: Interleukin-1beta increases the risk of gastric cancer through induction of aberrant DNA methylation in a mouse model. PMID: 27073577 Ref: FOXQ1 promotes gastric cancer metastasis through upregulation of Snail. PMID: 27109028 Ref: Prognosis of Pregnancy-Associated Gastric Cancer: An Age-, Sex-, and Stage-Matched Case-Control Study. PMID: 27114414 Ref: Knockdown of CMTM3 promotes metastasis of gastric cancer via the STAT3/Twist1/EMT signaling pathway. PMID: 27121055 Ref: MicroRNA-145-5p inhibits gastric cancer invasiveness through targeting N-cadherin and ZEB2 to suppress epithelial-mesenchymal transition. PMID: 27143926 Ref: Piperine treatment suppresses Helicobacter pylori toxin entry in to gastric epithelium and minimizes beta-catenin mediated oncogenesis and IL-8 secretion in vitro. PMID: 27158376 Ref: DDR1 enhances invasion and metastasis of gastric cancer via epithelial-mesenchymal transition. PMID: 27179963 Ref: An investigation of the factors effecting high-risk individuals' decision-making about prophylactic total gastrectomy and surveillance for hereditary diffuse gastric cancer (HDGC). PMID: 27256430 Ref: 7-Difluoromethoxyl-5,4'-di-n-octyl genistein inhibits the stem-like characteristics of gastric cancer stem-like cells and reverses the phenotype of epithelial-mesenchymal transition in gastric cancer cells. PMID: 27279287 Ref: Aldehyde dehydrogenase 3A1 is robustly upregulated in gastric cancer stem-like cells and associated with tumorigenesis. PMID: 27279633 Ref: Gastrokine-2 suppresses epithelial mesenchymal transition through PI3K/AKT/GSK3beta signaling in gastric cancer. PMID: 27323966 Ref: Hypermethylation Status of E-Cadherin Gene in Gastric Cancer Patients in a High Incidence Area. PMID: 27356686 Ref: miR-223/FBW7 axis regulates doxorubicin sensitivity through epithelial mesenchymal transition in non-small cell lung cancer. PMID: 27398136 Ref: Persisting and Increasing Neutrophil Infiltration Associates with Gastric Carcinogenesis and E-cadherin Downregulation. PMID: 27412620 Ref: Decreased expression of the long noncoding RNA LINC00261 indicate poor prognosis in gastric cancer and suppress gastric cancer metastasis by affecting the epithelial-mesenchymal transition. PMID: 27439973 Ref: Cate's Story: Hereditary Diffuse Gastric Cancer. PMID: 27441520 Ref: O-mannosylation and N-glycosylation: two coordinated mechanisms regulating the tumour suppressor functions of E-cadherin in cancer. PMID: 27533452 Ref: MiR-203 inhibits tumor invasion and metastasis in gastric cancer by ATM. PMID: 27542403 Ref: Tbx3 overexpression in human gastric cancer is correlated with advanced tumor stage and nodal status and promotes cancer cell growth and invasion. PMID: 27553355 Ref: Coupling CDH17 and CLDN18 markers for comprehensive membrane-targeted detection of human gastric cancer. PMID: 27580354 Ref: MicroRNA-21 promotes TGF-beta1-induced epithelial-mesenchymal transition in gastric cancer through up-regulating PTEN expression. PMID: 27611950 Ref: Establishment and characterization of an expanding-type gastric cancer cell line by Ming's classification. PMID: 27633271 Ref: PFK15, a Small Molecule Inhibitor of PFKFB3, Induces Cell Cycle Arrest, Apoptosis and Inhibits Invasion in Gastric Cancer. PMID: 27669567 Ref: Association between the CDH1-472delA and -160C>A polymorphisms and diffuse and intestinal gastric cancer in a Mexican population. PMID: 27706737 Ref: The effect of oxamflatin on the E-cadherin expression in gastric cancer cell line. PMID: 27767089 Ref: WIN 55,212-2 Inhibits the Epithelial Mesenchymal Transition of Gastric Cancer Cells via COX-2 Signals. PMID: 27802436 Ref: Advances in Understanding How Heavy Metal Pollution Triggers Gastric Cancer. PMID: 27803929 Ref: YAP1 enhances cell proliferation, migration, and invasion of gastric cancer in vitro and in vivo. PMID: 27835600 Ref: Knockdown of Radixin Suppresses Gastric Cancer Metastasis In Vitro by Up-Regulation of E-Cadherin via NF-kappaB/Snail Pathway. PMID: 27855404 Ref: MiR-30a Decreases Multidrug Resistance (MDR) of Gastric Cancer Cells. PMID: 27876712 Ref: Direct regulation of FOXK1 by C-jun promotes proliferation, invasion and metastasis in gastric cancer cells. PMID: 27882939 Ref: Genetic predisposition to gastric cancer. PMID: 27899187 Ref: Aspirin inhibits the proliferation and migration of gastric cancer cells in p53-knockout mice. PMID: 27899979 Ref: PBX3 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition. PMID: 27900025 Ref: Prophylactic Total Gastrectomy for Hereditary Diffuse Gastric Cancer. PMID: 28008412 |
Ref: Decitabine inhibits tumor cell proliferation and up-regulates e-cadherin expression in Epstein-Barr virus-associated gastric cancer. PMID: 27430892 Ref: The promotion of the transformation of quiescent gastric cancer stem cells by IL-17 and the underlying mechanisms. PMID: 27524415 Ref: Diffuse Gastric Carcinoma Undergoes Characteristic Phenotypic Changes in the Intravascular Environment: Evidence for a Reversal of the Epithelial-Mesenchymal Transition in Lymphovascular Metastasis. PMID: 27733664 Ref: Inhibition of CDH17 gene expression via RNA interference reduces proliferation and apoptosis of human MKN28 gastric cancer cells. PMID: 27909714 Ref: TGFbeta1-Induced LncRNA UCA1 Upregulation Promotes Gastric Cancer Invasion and Migration. PMID: 28075173 Ref: HIF-1alpha induces the epithelial-mesenchymal transition in gastric cancer stem cells through the Snail pathway. PMID: 28076840 Ref: MALAT1 promoted invasiveness of gastric adenocarcinoma. PMID: 28077118 Ref: Circular RNA 0000096 affects cell growth and migration in gastric cancer. PMID: 28081541 Ref: Liver X receptor alpha (LXRalpha) promoted invasion and EMT of gastric cancer cells by regulation of NF-kappaB activity. PMID: 28091828 Ref: TNF-alpha-inducing protein of Helicobacter pylori induces epithelial-mesenchymal transition (EMT) in gastric cancer cells through activation of IL-6/STAT3 signaling pathway. PMID: 28130110 Ref: MicroRNA-495 Inhibits Gastric Cancer Cell Migration and Invasion Possibly via Targeting High Mobility Group AT-Hook 2 (HMGA2). PMID: 28159956 Ref: Luteolin suppresses gastric cancer progression by reversing epithelial-mesenchymal transition via suppression of the Notch signaling pathway. PMID: 28241766 Ref: microRNA-203 suppresses invasion of gastric cancer cells by targeting ERK1/2/Slug/ E-cadherin signaling. PMID: 28269747 Ref: Basic Transcription Factor 3 Is Required for Proliferation and Epithelial-Mesenchymal Transition via Regulation of FOXM1 and JAK2/STAT3 Signaling in Gastric Cancer. PMID: 28276310 Ref: The role of MALAT-1 in the invasion and metastasis of gastric cancer. PMID: 28276823 Ref: Roles of RUNX in Hippo Pathway Signaling. PMID: 28299672 Ref: Introducing crucial protein panel of gastric adenocarcinoma disease. PMID: 28331560 Ref: From inflammation to gastric cancer: Role of Helicobacter pylori. PMID: 28356927 Ref: Protocadherin 7 inhibits cell migration and invasion through E-cadherin in gastric cancer. PMID: 28381163 Ref: CDH17 is a downstream effector of HOXA13 in modulating the Wnt/beta-catenin signaling pathway in gastric cancer. PMID: 28387908 Ref: REG3A promotes the proliferation, migration, and invasion of gastric cancer cells. PMID: 28435292 Ref: [Digoxin inhibits migration and invasion of human gastric carcinoma MKN45 cells through down-regulation of AEG-1]. PMID: 28435978 Ref: Plasma expression of the intestinal metaplasia markers CDH17 and TFF3 in patients with gastric cancer. PMID: 28453457 Ref: Relationships of MMP-9, E-cadherin, and VEGF expression with clinicopathological features and response to chemosensitivity in gastric cancer. PMID: 28459196 Ref: Bradykinin Promotes Cell Proliferation, Migration, Invasion, and Tumor Growth of Gastric Cancer Through ERK Signaling Pathway. PMID: 28464378 Ref: Membrane-bound beta-catenin degradation is enhanced by ETS2-mediated Siah1 induction in Helicobacter pylori-infected gastric cancer cells. PMID: 28481365 Ref: MicroRNA-217 suppressed epithelial-to-mesenchymal transition in gastric cancer metastasis through targeting PTPN14. PMID: 28485805 Ref: miR-551b regulates epithelial-mesenchymal transition and metastasis of gastric cancer by inhibiting ERBB4 expression. PMID: 28501849 Ref: MiR-2392 suppresses metastasis and epithelial-mesenchymal transition by targeting MAML3 and WHSC1 in gastric cancer. PMID: 28512191 Ref: Genetic Alterations in Gastric Cancer Associated with Helicobacter pylori Infection. PMID: 28512631 Ref: Yiqi Huayu Jiedu Decoction Inhibits the Invasion and Metastasis of Gastric Cancer Cells through TGF-beta/Smad Pathway. PMID: 28539961 Ref: Up-regulation of long non-coding RNA XLOC_010235 regulates epithelial-to-mesenchymal transition to promote metastasis by associating with Snail1 in gastric cancer. PMID: 28550287 Ref: Knockdown of long noncoding RNA GHET1 inhibits cell activation of gastric cancer. PMID: 28577495 Ref: MiR-133b inhibits proliferation and invasion of gastric cancer cells by up-regulating FBN1 expression. PMID: 28582847 Ref: Wnt10B is critical for the progression of gastric cancer. PMID: 28599424 Ref: FPR2 promotes invasion and metastasis of gastric cancer cells and predicts the prognosis of patients. PMID: 28600569 Ref: MicroRNA-630 Suppresses Epithelial-to-Mesenchymal Transition by Regulating FoxM1 in Gastric Cancer Cells. PMID: 28601080 Ref: EphA2 affects the sensitivity of oxaliplatin by inducing EMT in oxaliplatin-resistant gastric cancer cells. PMID: 28624791 Ref: EMP3 is induced by TWIST1/2 and regulates epithelial-to-mesenchymal transition of gastric cancer cells. PMID: 28718375 Ref: Calcium-binding protein S100A14 induces differentiation and suppresses metastasis in gastric cancer. PMID: 28726786 Ref: Oncogenic KRAS and p53 Loss Drive Gastric Tumorigenesis in Mice That Can Be Attenuated by E-Cadherin Expression. PMID: 28760854 Ref: Circ-104916 is downregulated in gastric cancer and suppresses migration and invasion of gastric cancer cells. PMID: 28761361 Ref: ERas is constitutively expressed in full term placenta of pregnant cows. PMID: 28787666 Ref: Hypoxia-inducible factor-1 alpha Correlates with Tumor-Associated Macrophages Infiltration, Influences Survival of Gastric Cancer Patients. PMID: 28819379 Ref: Expression and potential roles of sodium-potassium ATPase and E-cadherin in human gastric adenocarcinoma. PMID: 28832634 Ref: FOXM1 facilitates gastric cancer cell migration and invasion by inducing Cathepsin D. PMID: 28978107 Ref: Hispolon as an inhibitor of TGF-beta-induced epithelial-mesenchymal transition in human epithelial cancer cells by co-regulation of TGF-beta-Snail/Twist axis. PMID: 29085494 Ref: Diagnostic, Predictive, Prognostic, and Therapeutic Molecular Biomarkers in Third Millennium: A Breakthrough in Gastric Cancer. PMID: 29094049 Ref: Upregulation of T-cadherin suppresses cell proliferation, migration and invasion of gastric cancer in vitro. PMID: 29104635 Ref: Long noncoding RNA SNHG20 promotes gastric cancer progression by inhibiting p21 expression and regulating the GSK-3beta/ beta-catenin signaling pathway. PMID: 29113337 Ref: Aqueous Huaier Extract Suppresses Gastric Cancer Metastasis and Epithelial to Mesenchymal Transition by Targeting Twist. PMID: 29151976 Ref: [IL-6 promotes gastric cancer cell proliferation and EMT through regulating miR-152/PIK3R3 pathway]. PMID: 29187649 Ref: miR-302b inhibits tumorigenesis by targeting EphA2 via Wnt/ beta-catenin/EMT signaling cascade in gastric cancer. PMID: 29273006 Ref: Characterizing Metastatic HER2-Positive Gastric Cancer at the CDH1 Haplotype. PMID: 29295527 Ref: Melanoma differentiation-associated gene-7 suppresses human gastric cancer cell invasion and migration. PMID: 29344144 |
Ref: Loss of E-Cadherin-Dependent Cell-Cell Adhesion and the Development and Progression of Cancer. PMID: 28507022 Ref: A new mutation of the CDH1 gene in a patient with an aggressive signet-ring cell carcinoma of the stomach. PMID: 29131691 Ref: Downregulation of liver-intestine cadherin enhances cisplatin-induced apoptosis in human gastric cancer BGC823 cells. PMID: 29203930 Ref: FBXO2, a novel marker for metastasis in human gastric cancer. PMID: 29269301 Ref: miR-200c inhibits TGF-beta-induced-EMT to restore trastuzumab sensitivity by targeting ZEB1 and ZEB2 in gastric cancer. PMID: 29302045 Ref: PCDHGA9 acts as a tumor suppressor to induce tumor cell apoptosis and autophagy and inhibit the EMT process in human gastric cancer. PMID: 29348665 Ref: Arsenic trioxide attenuates STAT-3 activity and epithelial-mesenchymal transition through induction of SHP-1 in gastric cancer cells. PMID: 29409467 Ref: Merging perspectives: genotype-directed molecular therapy for hereditary diffuse gastric cancer (HDGC) and E-cadherin-EGFR crosstalk. PMID: 29468433 Ref: Synergistic Cytotoxic Effect on Gastric Cancer Cells of an Immunotoxin Cocktail in Which Antibodies Recognize Different Epitopes on CDH17. PMID: 29474162 Ref: Astragaloside IV inhibits TGF-beta1-induced epithelial-mesenchymal transition through inhibition of the PI3K/Akt/NF-kappaB pathway in gastric cancer cells. PMID: 29480652 Ref: miR-519d-3p Inhibits Cell Proliferation and Invasion of Gastric Cancer by Downregulating B-Cell Lymphoma 6. PMID: 29510377 Ref: Identification of selective inhibitors for diffuse-type gastric cancer cells by screening of annotated compounds in preclinical models. PMID: 29527007 Ref: Multi-omics analysis identifies pathways and genes involved in diffuse-type gastric carcinogenesis induced by E-cadherin, p53, and Smad4 loss in mice. PMID: 29528141 Ref: Identification of inhibitor against H. pylori HtrA protease using structure-based virtual screening and molecular dynamics simulations approaches. PMID: 29555508 Ref: PIAS1 inhibited the metastasis of gastric cancer cell by epithelial-mesenchymal transition regulation within the inflammatory microenvironment. PMID: 29556278 Ref: MicroRNA-338 inhibits proliferation, migration, and invasion of gastric cancer cells by the Wnt/beta-catenin signaling pathway. PMID: 29565486 Ref: Long noncoding RNA Lnc01614 promotes the occurrence and development of gastric cancer by activating EMT pathway. PMID: 29565488 Ref: Involvement of microRNAs-MMPs-E-cadherin in the migration and invasion of gastric cancer cells infected with Helicobacter pylori. PMID: 29604247 Ref: [beta-Lapachone combined with NVP-BEZ235 inhibit proliferation and migration of BGC-823 gastric cancer cells]. PMID: 29673455 Ref: Molecular mechanism of Poria cocos combined with oxaliplatin on the inhibition of epithelial-mesenchymal transition in gastric cancer cells. PMID: 29710543 Ref: DNA methyltransferase 3A isoform b contributes to repressing E-cadherin through cooperation of DNA methylation and H3K27/H3K9 methylation in EMT-related metastasis of gastric cancer. PMID: 29717263 Ref: Effects of glabridin combined with 5-fluorouracil on the proliferation and apoptosis of gastric cancer cells. PMID: 29725429 Ref: CircRNA_0023642 promotes migration and invasion of gastric cancer cells by regulating EMT. PMID: 29762831 Ref: Clinical and functional characterization of the CDH1 germline variant c.1679C>G in three unrelated families with hereditary diffuse gastric cancer. PMID: 29769627 Ref: TEMPORARY REMOVAL: CDH17 alters MMP-2 expression via canonical NF-kappaB signalling in human gastric cancer. PMID: 29783070 Ref: A novel de novo CDH1 germline variant aids in the classification of carboxy-terminal E-cadherin alterations predicted to escape nonsense-mediated mRNA decay. PMID: 29798843 Ref: Long non-coding RNA AFAP1-antisense RNA 1 promotes the proliferation, migration and invasion of gastric cancer cells and is associated with poor patient survival. PMID: 29805596 Ref: Long non-coding RNA GHET1 promotes human breast cancer cell proliferation, invasion and migration via affecting epithelial mesenchymal transition. PMID: 29843220 Ref: Targeting miR-9 in gastric cancer cells using locked nucleic acid oligonucleotides. PMID: 29879907 Ref: The Role of E-cadherin in Helicobacter pylori-Related Gastric Diseases. PMID: 29938616 Ref: KRAB zinc-finger protein 382 regulates epithelial-mesenchymal transition and functions as a tumor suppressor, but is silenced by CpG methylation in gastric cancer. PMID: 29956735 Ref: Effects of Celastrus orbiculatus on Epithelial Mesenchymal Transition in Gastric Mucosal Epithelial Cells by Inhibiting Lgr5 Expression from Rats with Gastric Precancerous Lesions. PMID: 29976080 Ref: Long Non-Coding RNA RP11-789C1.1 Suppresses Epithelial to Mesenchymal Transition in Gastric Cancer Through the RP11-789C1.1/MiR-5003/E-Cadherin Axis. PMID: 29991048 Ref: 12-Lipoxygenase promotes invasion and metastasis of human gastric cancer cells via epithelial-mesenchymal transition. PMID: 30008824 Ref: Metastasis suppressor protein 1 regulated by PTEN suppresses invasion, migration, and EMT of gastric carcinoma by inactivating PI3K/AKT signaling. PMID: 30013632 Ref: Upregulation of EphB3 in gastric cancer with acquired resistance to a FGFR inhibitor. PMID: 30044964 Ref: DcR3 induces proliferation, migration, invasion, and EMT in gastric cancer cells via the PI3K/AKT/GSK-3beta/beta-catenin signaling pathway. PMID: 30050309 Ref: [DS2, a newly synthetic ent-kaurane diterpenoid analog, inhibits proliferation and migration of human gastric cancer cell]. PMID: 30060356 Ref: Neogenin-1 Promotes Cell Proliferation, Motility, and Adhesion by Up-Regulation of Zinc Finger E-Box Binding Homeobox 1 Via Activating the Rac1/PI3K/AKT Pathway in Gastric Cancer Cells. PMID: 30064133 Ref: Polyphyllin I inhibits growth and invasion of cisplatin-resistant gastric cancer cells by partially inhibiting CIP2A/PP2A/Akt signaling axis. PMID: 30119963 Ref: E2F1 induces LSINCT5 transcriptional activity and promotes gastric cancer progression by affecting the epithelial-mesenchymal transition. PMID: 30127643 Ref: Early genetic counseling and detection of CDH1 mutation in asymptomatic carriers improves survival in hereditary diffuse gastric cancer. PMID: 30145018 Ref: MicroRNA-133a inhibits gastric cancer cells growth, migration, and epithelial-mesenchymal transition process by targeting presenilin 1. PMID: 30161272 Ref: Metastasis suppressor protein 1 regulated by PTEN suppresses invasion, migration, and EMT of gastric carcinoma by inactivating PI3K/AKT signaling. PMID: 30246429 Ref: Upregulation of long noncoding RNA CCAT1-L promotes epithelial-mesenchymal transition in gastric adenocarcinoma. PMID: 30254457 Ref: Establishment and Characterization of gc-006-03, a Novel Human Signet Ring Cell Gastric Cancer Cell Line Derived from Metastatic Ascites. PMID: 30271482 Ref: Cleft lip/palate and hereditary diffuse gastric cancer: report of a family harboring a CDH1 c.687 + 1G > A germline mutation and review of the literature. PMID: 30306390 Ref: Hypermethylation of miR-338-3p and Impact of its Suppression on Cell Metastasis Through N-Cadherin Accumulation at the Cell -Cell Junction and Degradation of MMP in Gastric Cancer. PMID: 30308487 Ref: HOXB9 inhibits proliferation in gastric carcinoma cells via suppression of phosphorylated-Akt and NF-kappaB-dependent Snail expression. PMID: 30314948 Ref: Antitumor evaluation of novel phenothiazine derivatives that inhibit migration and tubulin polymerization against gastric cancer MGC-803 cells. PMID: 30345465 |