Primary Site >> Colorectal Cancer
Gene >> CDH17
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Ref: Complete amino acid sequence of the epidermal desmoglein precursor polypeptide and identification of a second type of desmoglein gene. PMID: 1935985 |
Ref: Morphoregulatory activities of E-cadherin and beta-1 integrins in colorectal tumour cells. PMID: 1384639 Ref: Cloning and characterization of a gene that regulates cell adhesion. PMID: 1560826 |
Ref: [Metastasis related genes and malignancy in human esophageal, gastric and colorectal cancers]. PMID: 8094950 Ref: Association of the APC tumor suppressor protein with catenins. PMID: 8259519 Ref: Phorbol ester-induced scattering of HT-29 human intestinal cancer cells is associated with down-modulation of E-cadherin. PMID: 8282758 Ref: Models of colorectal tumour differentiation. PMID: 8348537 Ref: Molecular mechanism of stomach carcinogenesis. PMID: 8440743 |
Ref: Reduced E-cadherin expression correlates with increased invasiveness in colorectal carcinoma cell lines. PMID: 8039307 Ref: Soluble fragments of e-cadherin cell-adhesion molecule increase in urinary-excretion of cancer-patients, potentially indicating its shedding from epithelial tumor-cells. PMID: 21559679 |
Ref: Role of the E-cadherin/alpha-catenin complex in modulating cell-cell and cell-matrix adhesive properties of invasive colon carcinoma cells. PMID: 7496831 Ref: Transition from the noninvasive to the invasive phenotype and loss of alpha-catenin in human colon cancer cells. PMID: 7553655 Ref: [Correlation between the intercellular adhesion molecule (E-cadherin) and its associated protein (alpha-catenin) expression and metastasis in human digestive cancers]. PMID: 7629995 Ref: Inhibition of cancer cell motility and invasion by interleukin-12. PMID: 7641424 Ref: The tyrosine kinase substrate p120cas binds directly to E-cadherin but not to the adenomatous polyposis coli protein or alpha-catenin. PMID: 7651399 Ref: Inhibition of hepatocyte growth factor-induced motility and in vitro invasion of human colon cancer cells by gamma-linolenic acid. PMID: 7710939 Ref: Activation of the E-cadherin/catenin complex in human MCF-7 breast cancer cells by all-trans-retinoic acid. PMID: 8519658 |
Ref: Formation of focal adhesion and spreading of polarized human colon cancer cells in association with tyrosine phosphorylation of paxillin in response to phorbol ester. PMID: 8569182 Ref: Suppression of tumorigenicity by plakoglobin: an augmenting effect of N-cadherin. PMID: 8601608 Ref: p120-catenin expression in human colorectal cancer. PMID: 8895533 |
Ref: Progression of familial adenomatous polyposis (FAP) colonic cells after transfer of the src or polyoma middle T oncogenes: cooperation between src and HGF/Met in invasion. PMID: 9010033 Ref: Expression of E-cadherin, alpha, beta and gamma-catenin in human colorectal cancer. PMID: 9137497 Ref: Protein kinase C activation upregulates intercellular adhesion of alpha-catenin-negative human colon cancer cell variants via induction of desmosomes. PMID: 9166410 Ref: Frequent mutation of the E2F-4 cell cycle gene in primary human gastrointestinal tumors. PMID: 9192806 Ref: Reduced expression of molecules of the cadherin/catenin complex in the transition from colorectal adenoma to carcinoma. PMID: 9216695 Ref: [Genetic and environmental factors in colorectal cancer. Mutations in the familial adenomatous polyposis gene]. PMID: 9235686 Ref: [Molecular etiology of colorectal carcinogenesis, clinical manifestations and therapy]. PMID: 9244653 Ref: The interactions of APC, E-cadherin and beta-catenin in tumour development and progression. PMID: 9274521 Ref: Beta-catenin mutations in cell lines established from human colorectal cancers. PMID: 9294210 Ref: Reciprocity between membranous and nuclear expression of beta-catenin in colorectal tumours. PMID: 9334837 Ref: Identification of four distinct pools of catenins in mammalian cells and transformation-dependent changes in catenin distributions among these pools. PMID: 9368032 Ref: Functional downregulation of the E-cadherin/catenin complex leads to loss of contact inhibition of motility and of mitochondrial activity, but not of growth in confluent epithelial cell cultures. PMID: 9438130 Ref: Cadherin and catenin biology represent a global mechanism for epithelial cancer progression. PMID: 9536277 |
Ref: Beta-catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors. PMID: 9426055 Ref: Aberrant expression and phosphorylation of beta-catenin in human colorectal cancer. PMID: 9484818 Ref: Intestinal trefoil factor controls the expression of the adenomatous polyposis coli-catenin and the E-cadherin-catenin complexes in human colon carcinoma cells. PMID: 9501226 Ref: Modulation of hepatocyte growth factor-induced scattering of HT29 colon carcinoma cells. Involvement of the MAPK pathway. PMID: 9512500 Ref: Mutations in the beta-catenin gene (CTNNB1) in endometrioid ovarian carcinomas. PMID: 9537226 Ref: Acquisition of cell adhesion and induction of focal adhesion kinase of human colon cancer Colo 201 cells by retinoic acid-induced differentiation. PMID: 9566310 Ref: Level of alpha-catenin expression in colorectal cancer correlates with invasiveness, metastatic potential, and survival. PMID: 9624037 Ref: Differential nuclear translocation and transactivation potential of beta-catenin and plakoglobin. PMID: 9628899 Ref: Preparation and characterization of differently aggregated colorectal carcinoma cell subpopulations from surgical specimens. PMID: 9674875 Ref: alpha-Catenin-vinculin interaction functions to organize the apical junctional complex in epithelial cells. PMID: 9700171 Ref: [Dysfunction of E-cadherin-catenin system in invasion and metastasis of colorectal cancer]. PMID: 9742518 Ref: A mutation in alpha-catenin disrupts adhesion in clone A cells without perturbing its actin and beta-catenin binding activity. PMID: 9762469 Ref: Dysregulation of the E-cadherin/catenin complex by irreversible mutations in human carcinomas. PMID: 9823469 Ref: Hepatocyte growth factor/scatter factor induces not only scattering but also cohort migration of human colorectal-adenocarcinoma cells. PMID: 9833769 |
Ref: Activation of protein kinase C modulates cell-cell and cell-substratum adhesion of a human colorectal carcinoma cell line and restores 'normal' epithelial morphology. PMID: 9935190 Ref: Mutated epithelial cadherin is associated with increased tumorigenicity and loss of adhesion and of responsiveness to the motogenic trefoil factor 2 in colon carcinoma cells. PMID: 10051639 Ref: Germline E-cadherin gene (CDH1) mutations predispose to familial gastric cancer and colorectal cancer. PMID: 10072428 Ref: Transforming growth factor beta stimulation of colorectal cancer cell lines: type II receptor bypass and changes in adhesion molecule expression. PMID: 10077641 Ref: E-cadherin binding prevents beta-catenin nuclear localization and beta-catenin/LEF-1-mediated transactivation. PMID: 10085258 Ref: Immunohistological analysis of E-cadherin, alpha-, beta- and gamma-catenin expression in colorectal cancer: implications for cell adhesion and signaling. PMID: 10211089 Ref: p120(ctn) acts as an inhibitory regulator of cadherin function in colon carcinoma cells. PMID: 10225956 Ref: An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin. PMID: 10228155 Ref: The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. PMID: 10318916 Ref: Dysregulation of beta-catenin is common in canine sporadic colorectal tumors. PMID: 10332831 Ref: Cadherin-catenin expression in primary colorectal cancer: a survival analysis. PMID: 10362114 Ref: Beta- and gamma-catenin mutations, but not E-cadherin inactivation, underlie T-cell factor/lymphoid enhancer factor transcriptional deregulation in gastric and pancreatic cancer. PMID: 10392898 Ref: beta-catenin expression in primary and metastatic colorectal carcinoma. PMID: 10404062 Ref: Nuclear beta-catenin in colorectal tumors: to freeze or not to freeze? Colon Cancer Team at IMAS. PMID: 10424893 Ref: Association of the HGF/SF receptor, c-met, with the cell-surface adhesion molecule, E-cadherin, and catenins in human tumor cells. PMID: 10425198 Ref: Ezrin regulates cell-cell and cell-matrix adhesion, a possible role with E-cadherin/beta-catenin. PMID: 10462524 Ref: Distinct methylation pattern and microsatellite instability in sporadic gastric cancer. PMID: 10495421 Ref: Cohort migration of carcinoma cells: differentiated colorectal carcinoma cells move as coherent cell clusters or sheets. PMID: 10506935 Ref: Changes of E-cadherin and beta-catenin levels during induced differentiation of colorectal carcinoma cells. PMID: 10534578 Ref: beta-catenin signaling and cancer. PMID: 10580987 Ref: Reduction in membranous expression of beta-catenin and increased cytoplasmic E-cadherin expression predict poor survival in gastric cancer. PMID: 10604738 Ref: Cross-regulation of beta-catenin-LEF/TCF and retinoid signaling pathways. PMID: 10607566 Ref: Molecular biology of gastric carcinoma: from laboratory to bedside. PMID: 10634150 Ref: The role of the E-cadherin/catenin complex in gastrointestinal cancer. PMID: 10692769 Ref: A colorectal cell line with alterations in E-cadherin and epithelial biology may be an in vitro model of colitis. PMID: 10694944 Ref: [Molecular carcinogenesis in ulcerative colitis-associated and sporadic colorectal carcinoma--differences and similarities]. PMID: 10714203 |
Ref: Butyrate regulates E-cadherin transcription, isoform expression and intracellular position in colon cancer cells. PMID: 10638989 Ref: p21WAF1 regulates anchorage-independent growth of HCT116 colon carcinoma cells via E-cadherin expression. PMID: 10646868 Ref: [Effect of laminin antisense RNA on the expression of five intracellular proteins stimulated by transforming growth factor beta(1)]. PMID: 10751536 Ref: The E-cadherin gene (CDH1) variants T340A and L599V in gastric and colorectal cancer patients in Korea. PMID: 10896919 Ref: Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin. PMID: 11035789 Ref: Induction of invasion in vivo of alpha-catenin-positive HCT-8 human colon-cancer cells. PMID: 11072244 |
Ref: Hypermethylation of the promoter region of the E-cadherin gene (CDH1) in sporadic and ulcerative colitis associated colorectal cancer. PMID: 11171827 Ref: Altered distribution of beta-catenin, and its binding proteins E-cadherin and APC, in ulcerative colitis-related colorectal cancers. PMID: 11211307 Ref: Truncated DCC reduces N-cadherin/catenin expression and calcium-dependent cell adhesion in neuroblastoma cells. PMID: 11232642 Ref: Inhibition of integrin linked kinase (ILK) suppresses beta-catenin-Lef/Tcf-dependent transcription and expression of the E-cadherin repressor, snail, in APC-/- human colon carcinoma cells. PMID: 11244511 Ref: Requirement of protein kinase Calpha, extracellular matrix remodeling, and cell-matrix interaction for transforming growth factorbeta-regulated expression of E-cadherin and catenins. PMID: 11267998 Ref: Increased beta-catenin expression and nuclear translocation accompany cellular hyperproliferation in vivo. PMID: 11306465 Ref: Down-regulation of beta-catenin TCF signaling is linked to colonic epithelial cell differentiation. PMID: 11309309 Ref: Changes of E-cadherin and beta-catenin in human and mouse intestinal tumours. PMID: 11352396 Ref: Tyrosine phosphorylation translocates beta-catenin from cell-->cell interface to the cytoplasm, but does not significantly enhance the LEF-1-dependent transactivating function. PMID: 11401329 Ref: Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling. PMID: 11470825 Ref: The cadherin-catenin superfamily in endocrine tumors. PMID: 11478263 Ref: Expression of alpha-catenin in alpha-catenin-deficient cells increases resistance to sphingosine-induced apoptosis. PMID: 11489917 Ref: Immunohistochemical analysis of candidate gene product expression in the duodenal epithelium of children with coeliac sprue. PMID: 11533074 Ref: HGF upregulates and modifies subcellular distribution of proteins in colon cancer cell enterocytic differentiation. PMID: 11557528 Ref: A germline E-cadherin mutation in a family with gastric and colon cancer. PMID: 11562785 Ref: Correlation of beta-catenin and cyclin D1 expression in colon cancers. PMID: 11574779 Ref: alphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion. PMID: 11590244 Ref: The expression of E-cadherin and catenins in sporadic colorectal carcinoma. PMID: 11727261 Ref: Possible contribution of CD44 variant 6 and nuclear beta-catenin expression to the formation of budding tumor cells in patients with T1 colorectal carcinoma. PMID: 11745187 |
Ref: Reduced expression of EphrinA1 (EFNA1) inhibits three-dimensional growth of HT29 colon carcinoma cells. PMID: 11741747 Ref: Tumor necrosis factor alpha stimulates invasion of Src-activated intestinal cells. PMID: 11832448 Ref: Protection against anoikis and down-regulation of cadherin expression by a regulatable beta-catenin protein. PMID: 11904289 Ref: Molecular histology in the study of solid tumours. PMID: 11950953 Ref: Beta-catenin expression and allelic loss at APC in sporadic colorectal carcinogenesis. PMID: 11956815 Ref: Increased Src activity disrupts cadherin/catenin-mediated homotypic adhesion in human colon cancer and transformed rodent cells. PMID: 11980666 Ref: Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation. PMID: 12060769 Ref: Aberrant methylation of the CDH13 (H-cadherin) promoter region in colorectal cancers and adenomas. PMID: 12067979 Ref: Novel colon cancer cell lines leading to better understanding of the diversity of respective primary cancers. PMID: 12096341 Ref: Protocadherin LKC, a new candidate for a tumor suppressor of colon and liver cancers, its association with contact inhibition of cell proliferation. PMID: 12117771 Ref: Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling. PMID: 12134161 Ref: Nr-CAM is a target gene of the beta-catenin/LEF-1 pathway in melanoma and colon cancer and its expression enhances motility and confers tumorigenesis. PMID: 12183361 Ref: Complex formation of IQGAP1 with E-cadherin/catenin during cohort migration of carcinoma cells. Its possible association with localized release from cell-cell adhesion. PMID: 12189501 Ref: Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells. PMID: 12203117 Ref: Epigenetic control of the E-cadherin gene (CDH1) by CpG methylation in colectomy samples of patients with ulcerative colitis. PMID: 12203775 Ref: Variable nuclear localization of alpha-catenin in colorectal carcinoma. PMID: 12218077 Ref: CDX2 regulates liver intestine-cadherin expression in normal and malignant colon epithelium and intestinal metaplasia. PMID: 12404231 Ref: [High concentration of E-cadherin in portal drainage vein of colorectal cancer patients may predict metachronous liver metastasis]. PMID: 12484050 Ref: Altered expression of the catenin p120 in human cancer: implications for tumor progression. PMID: 12492499 Ref: Ursodeoxycholic acid and F(6)-D(3) inhibit aberrant crypt proliferation in the rat azoxymethane model of colon cancer: roles of cyclin D1 and E-cadherin. PMID: 12496057 |
Ref: Extracellular calcium and calcium sensing receptor function in human colon carcinomas: promotion of E-cadherin expression and suppression of beta-catenin/TCF activation. PMID: 12517779 Ref: Decreased syndecan-2 expression correlates with trichostatin-A induced-morphological changes and reduced tumorigenic activity in colon carcinoma cells. PMID: 12584561 Ref: Requirement of both mucins and proteoglycans in cell-cell dissociation and invasiveness of colon carcinoma HT-29 cells. PMID: 12640674 Ref: Alkylphospholipids reversibly open epithelial tight junctions. PMID: 12680191 Ref: Cells heterozygous for the ApcMin mutation have decreased gap junctional intercellular communication and connexin43 level, and reduced microtubule polymerization. PMID: 12727791 Ref: Muc4/sialomucin complex, the intramembrane ErbB2 ligand, translocates ErbB2 to the apical surface in polarized epithelial cells. PMID: 12748185 Ref: Abnormalities of the cadherin-catenin complex in chemically-induced colo-rectal carcinogenesis. PMID: 12756972 Ref: Overexpression of the thymosin beta-4 gene is associated with malignant progression of SW480 colon cancer cells. PMID: 12761500 Ref: Expression of beta-catenin in basal cell carcinoma. PMID: 12786827 Ref: E-cadherin involved in inactivation of WNT/beta-catenin signalling in urothelial carcinoma and normal urothelial cells. PMID: 12799639 Ref: [Roles of beta-catenin overexpression and adenomatous polyposis coli mutation in head and neck cancer]. PMID: 12872724 Ref: Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases. PMID: 12915469 Ref: Overexpression of the beta-catenin binding domain of cadherin selectively kills colorectal cancer cells. PMID: 12949799 Ref: A protein knockdown strategy to study the function of beta-catenin in tumorigenesis. PMID: 14516475 Ref: Functional and molecular characterization of the epithelioid to round transition in human colorectal cancer LoVo cells. PMID: 14562048 Ref: Autoregulation of E-cadherin expression by cadherin-cadherin interactions: the roles of beta-catenin signaling, Slug, and MAPK. PMID: 14623871 Ref: Matrilysin (MMP-7) induces homotypic adhesion of human colon cancer cells and enhances their metastatic potential in nude mouse model. PMID: 14647460 |
Ref: Density-dependent location and interactions of truncated APC and beta-catenin. PMID: 14647421 Ref: Restoration of full-length adenomatous polyposis coli (APC) protein in a colon cancer cell line enhances cell adhesion. PMID: 14679305 Ref: HGF and ligation of alphavbeta5 integrin induce a novel, cancer cell-specific gene expression required for cell scattering. PMID: 14697335 Ref: Csk defines the ability of integrin-mediated cell adhesion and migration in human colon cancer cells: implication for a potential role in cancer metastasis. PMID: 14712234 Ref: Roles of phosphatidylinositol 3'-kinase and mammalian target of rapamycin/p70 ribosomal protein S6 kinase in K-Ras-mediated transformation of intestinal epithelial cells. PMID: 14729629 Ref: Expression of alpha-catenin in alpha-catenin-deficient cells results in a reduced proliferation in three-dimensional multicellular spheroids but not in two-dimensional monolayer cultures. PMID: 14755240 Ref: Alpha-catenin is required for IGF-I-induced cellular migration but not invasion in human colonic cancer cells. PMID: 14961074 Ref: Src SH3/2 domain-mediated peripheral accumulation of Src and phospho-myosin is linked to deregulation of E-cadherin and the epithelial-mesenchymal transition. PMID: 15075377 Ref: Disruption of STAT3 signaling leads to tumor cell invasion through alterations of homotypic cell-cell adhesion complexes. PMID: 15077188 Ref: Geno- and pheno-typic characterization in ten patients with double-primary gastric and colorectal adenocarcinomas. PMID: 15083323 Ref: Loss of Smad4 correlates with loss of the invasion suppressor E-cadherin in advanced colorectal carcinomas. PMID: 15095268 Ref: Transforming growth factor beta regulates cell-cell adhesion through extracellular matrix remodeling and activation of focal adhesion kinase in human colon carcinoma Moser cells. PMID: 15133493 Ref: Characterization of the E-cadherin/catenin complex in colorectal carcinoma cell lines. PMID: 15154912 Ref: Intravasation-related metastatic factors in colorectal cancer. PMID: 15192312 Ref: Inducible expression of p120Cas1B isoform corroborates the role for p120-catenin as a positive regulator of E-cadherin function in intestinal cancer cells. PMID: 15219847 Ref: Overexpression of the thymosin beta-4 gene is associated with increased invasion of SW480 colon carcinoma cells and the distant metastasis of human colorectal carcinoma. PMID: 15235586 Ref: Reduced expression of liver-intestine cadherin is associated with progression and lymph node metastasis of human colorectal carcinoma. PMID: 15279905 Ref: Thiazolidinedione, a peroxisome proliferator-activated receptor-gamma ligand, inhibits growth and metastasis of HT-29 human colon cancer cells through differentiation-promoting effects. PMID: 15289864 Ref: Critical role of N-cadherin in myofibroblast invasion and migration in vitro stimulated by colon-cancer-cell-derived TGF-beta or wounding. PMID: 15331629 Ref: CSE1/CAS overexpression inhibits the tumorigenicity of HT-29 colon cancer cells. PMID: 15354419 Ref: Down-regulation of SNAIL suppresses MIN mouse tumorigenesis: modulation of apoptosis, proliferation, and fractal dimension. PMID: 15367710 Ref: Zinc stabilizes adenomatous polyposis coli (APC) protein levels and induces cell cycle arrest in colon cancer cells. PMID: 15368361 Ref: Paradoxically enhanced immunoreactivity of hepatocyte growth factor activator inhibitor type 1 (HAI-1) in cancer cells at the invasion front. PMID: 15471558 Ref: Transactivation of E-cadherin is not involved in the activity of EGF receptor in colorectal carcinoma cells. PMID: 15492839 Ref: Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis. PMID: 15526363 Ref: The dietary phytochemical chlorophyllin alters E-cadherin and beta-catenin expression in human colon cancer cells. PMID: 15570051 |
Ref: Modulation of tumor formation and intestinal cell migration by estrogens in the Apc(Min/+) mouse model of colorectal cancer. PMID: 15579483 Ref: Epigenetics, mismatch repair genes and colorectal cancer. PMID: 15720901 Ref: CDX2 co-localizes with liver-intestine cadherin in intestinal metaplasia and adenocarcinoma of the stomach. PMID: 15732140 Ref: MET signalling in primary colon epithelial cells leads to increased transformation irrespective of aberrant Wnt signalling. PMID: 15785735 Ref: Synthesis of junctional proteins in metastasizing colon cancer cells. PMID: 15819418 Ref: The epithelial-mesenchymal transition (EMT) and colorectal cancer progression. PMID: 15846061 Ref: Frizzled-7 receptor ectodomain expression in a colon cancer cell line induces morphological change and attenuates tumor growth. PMID: 15901282 Ref: The SRC-induced mesenchymal state in late-stage colon cancer cells. PMID: 15942195 Ref: Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer. PMID: 15965503 Ref: New concepts of molecular biology on gastric carcinogenesis. PMID: 16001683 Ref: Global gene expression analysis in time series following N-acetyl L-cysteine induced epithelial differentiation of human normal and cancer cells in vitro. PMID: 16001974 Ref: Lysosomal trafficking of beta-catenin induced by the tea polyphenol epigallocatechin-3-gallate. PMID: 16054165 Ref: E-cadherin and vitamin D receptor regulation by SNAIL and ZEB1 in colon cancer: clinicopathological correlations. PMID: 16203744 Ref: E-cadherin regulates the association between beta-catenin and actinin-4. PMID: 16204054 Ref: Biosensor-based micro-affinity purification for the proteomic analysis of protein complexes. PMID: 16212417 Ref: Identification of regions of alpha-catenin required for desmosome organization in epithelial cells. PMID: 16273278 Ref: Inhibition of intestinal tumorigenesis in Apcmin/+ mice by (-)-epigallocatechin-3-gallate, the major catechin in green tea. PMID: 16288056 Ref: Altered localization of p120 catenin during epithelial to mesenchymal transition of colon carcinoma is prognostic for aggressive disease. PMID: 16322241 |
Ref: An increase in the number of adhesion proteins with altered expression is associated with an increased risk of cancer death for colon carcinoma patients. PMID: 15937692 Ref: Effect of indomethacin on E-cadherin and beta-catenin expression in HT-29 colon cancer cells. PMID: 15963497 Ref: Roles and regulation of Wnt signaling and beta-catenin in prostate cancer. PMID: 16023783 Ref: Anti-proliferative effects of green tea polyphenol EGCG on Ha-Ras-induced transformation of intestinal epithelial cells. PMID: 16157446 Ref: ILK over-expression in human colon cancer progression correlates with activation of beta-catenin, down-regulation of E-cadherin and activation of the Akt-FKHR pathway. PMID: 16278819 Ref: The leukocyte protein L-plastin induces proliferation, invasion and loss of E-cadherin expression in colon cancer cells. PMID: 16287074 Ref: Overexpression of ADAM9 enhances growth factor-mediated recycling of E-cadherin in human colon cancer cell line HT29 cells. PMID: 16336960 Ref: Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility. PMID: 16368433 Ref: E-cadherin modulates Wnt-dependent transcription in colorectal cancer cells but does not alter Wnt-independent gene expression in fibroblasts. PMID: 16368435 Ref: Overexpressed LEF-1 proteins display different nuclear localization patterns of beta-catenin in normal versus tumor cells. PMID: 16378739 Ref: Vangl1 protein acts as a downstream effector of intestinal trefoil factor (ITF)/TFF3 signaling and regulates wound healing of intestinal epithelium. PMID: 16410243 Ref: Prognostic value of E-cadherin, beta-catenin, MMPs (7 and 9), and TIMPs (1 and 2) in patients with colorectal carcinoma. PMID: 16425303 Ref: Expression of Wnt-signaling pathway proteins in intraductal papillary mucinous neoplasms of the pancreas: a tissue microarray analysis. PMID: 16426922 Ref: SKI-606 decreases growth and motility of colorectal cancer cells by preventing pp60(c-Src)-dependent tyrosine phosphorylation of beta-catenin and its nuclear signaling. PMID: 16489032 Ref: Colon cancer cells: pro-invasive signalling. PMID: 16513408 Ref: Protein-tyrosine phosphatase PCP-2 inhibits beta-catenin signaling and increases E-cadherin-dependent cell adhesion. PMID: 16574648 Ref: Requirement of the enzymatic and signaling activities of plasmin for phorbol-ester-induced scattering of colon cancer cells. PMID: 16631161 Ref: Hypoxia-inducible factor-1alpha induces the epithelial-mesenchymal transition of human prostatecancer cells. PMID: 16701010 Ref: Direct interaction of the C-terminal domain of alpha-catenin and F-actin is necessary for stabilized cell-cell adhesion. PMID: 16798615 Ref: Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines. PMID: 16857785 Ref: Chemoprevention of colon carcinogenesis by polyethylene glycol: suppression of epithelial proliferation via modulation of SNAIL/beta-catenin signaling. PMID: 16928827 Ref: E-cadherin regulates human Nanos1, which interacts with p120ctn and induces tumor cell migration and invasion. PMID: 17047063 Ref: Morphological and molecular alterations at the junctional complex in irradiated human colon adenocarcinoma cells, Caco-2. PMID: 17050478 Ref: Tiam1 regulates cell adhesion, migration and apoptosis in colon tumor cells. PMID: 17086355 Ref: RhoA mediates cyclooxygenase-2 signaling to disrupt the formation of adherens junctions and increase cell motility. PMID: 17178865 |
Ref: Frizzled-7 dictates three-dimensional organization of colorectal cancer cell carcinoids. PMID: 17016432 Ref: Thymosin beta4 triggers an epithelial-mesenchymal transition in colorectal carcinoma by upregulating integrin-linked kinase. PMID: 17072345 Ref: Truncated isoform of mouse alphaT-catenin is testis-restricted in expression and function. PMID: 17185752 Ref: Identification of seven novel germline mutations in the human E-cadherin (CDH1) gene. PMID: 17221870 Ref: Loss of AP-2alpha results in deregulation of E-cadherin and MMP-9 and an increase in tumorigenicity of colon cancer cells in vivo. PMID: 17224907 Ref: Establishment and characterization of a novel human colorectal cancer cell line (CLY) metastasizing spontaneously to the liver in nude mice. PMID: 17342324 Ref: Activation of tumor-specific splice variant Rac1b by dishevelled promotes canonical Wnt signaling and decreased adhesion of colorectal cancer cells. PMID: 17363564 Ref: Elucidating the interactions between the adhesive and transcriptional functions of beta-catenin in normal and cancerous cells. PMID: 17382967 Ref: Prognostic significance of the wnt signalling pathway molecules APC, beta-catenin and E-cadherin in colorectal cancer: a tissue microarray-based analysis. PMID: 17448021 Ref: The Wnt antagonist DICKKOPF-1 gene is induced by 1alpha,25-dihydroxyvitamin D3 associated to the differentiation of human colon cancer cells. PMID: 17449905 Ref: The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity. PMID: 17486063 Ref: Role of APAF-1, E-cadherin and peritumoral lymphocytic infiltration in tumour budding in colorectal cancer. PMID: 17516584 Ref: Regulation of E-cadherin and beta-catenin by Ca2+ in colon carcinoma is dependent on calcium-sensing receptor expression and function. PMID: 17557293 Ref: Antiproliferative effect of conjugated linoleic acid in caco-2 cells: involvement of PPARgamma and APC/beta-catenin pathways. PMID: 17632092 Ref: Clusterin expression can be modulated by changes in TCF1-mediated Wnt signaling. PMID: 17634137 Ref: An active Src kinase-beta-actin association is linked to actin dynamics at the periphery of colon cancer cells. PMID: 17651734 Ref: Molecular portrait of cisplatin induced response in human testis cancer cell lines based on gene expression profiles. PMID: 17711579 Ref: E-cadherin is required for caveolin-1-mediated down-regulation of the inhibitor of apoptosis protein survivin via reduced beta-catenin-Tcf/Lef-dependent transcription. PMID: 17785436 Ref: The prognostic significance of E-cadherin and liver intestine-cadherin expression in colorectal cancer. PMID: 17828401 Ref: beta-Catenin signaling in biological control and cancer. PMID: 17854061 Ref: [Effects of hFRNK on E-cadherin/beta-catenin in colon cancer cells in vitro]. PMID: 17892129 Ref: EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells. PMID: 17906625 Ref: SND1, a component of RNA-induced silencing complex, is up-regulated in human colon cancers and implicated in early stage colon carcinogenesis. PMID: 17909068 |
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