Primary Site >> Esophagus Cancer

Gene >> CDH1

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Ref: Frequent hypermethylation of the 5' CpG island of E-cadherin in esophageal adenocarcinoma.
PMID: 11555590
Ref: Accumulation of promoter methylation suggests epigenetic progression in squamous cell carcinoma of the esophagus.
PMID: 16899597
Ref: Cathepsin B is the driving force of esophageal cell invasion in a fibroblast-dependent manner.
PMID: 20563251
Ref: Functional polymorphisms associated with disease-free survival in resected carcinoma of the esophagus.
PMID: 20922573
Ref: Hypermethylation-modulated down-regulation of CDH1 expression contributes to the progression of esophageal cancer.
PMID: 21373750
Ref: Concerted loss of TGFbeta-mediated proliferation control and E-cadherin disrupts epithelial homeostasis and causes oral squamous cell carcinoma.
PMID: 25233932
Ref: FOXQ1 promotes esophageal cancer proliferation and metastasis by negatively modulating CDH1.
PMID: 26349968
Ref: 5-Azacytidine suppresses EC9706 cell proliferation and metastasis by upregulating the expression of SOX17 and CDH1.
PMID: 27513557
Ref: Decreased expression of CDH1 or CTNNB1 affects poor prognosis of patients with esophageal cancer.
PMID: 27600761
Ref: Esophageal Adenocarcinoma Cells and Xenograft Tumors Exposed to Erb-b2 Receptor Tyrosine Kinase 2 and 3 Inhibitors Activate Transforming Growth Factor Beta Signaling, Which Induces Epithelial to Mesenchymal Transition.
PMID: 28286209