Primary Site >> Pancreatic Cancer
Gene >> CDC42
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Ref: Molecular cloning and characterization of WRCH2 on human chromosome 15q15. PMID: 11956592 |
Ref: Identification and characterization of ARHGAP27 gene in silico. PMID: 15492870 |
Ref: Overexpressed P-cadherin/CDH3 promotes motility of pancreatic cancer cells by interacting with p120ctn and activating rho-family GTPases. PMID: 15833838 |
Ref: Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs. PMID: 17273804 |
Ref: Inhibition of peroxisome proliferator-activated receptor gamma activity suppresses pancreatic cancer cell motility. PMID: 19016747 |
Ref: Rac1 activation inhibits E-cadherin-mediated adherens junctions via binding to IQGAP1 in pancreatic carcinoma cells. PMID: 19737400 |
Ref: p8 expression controls pancreatic cancer cell migration, invasion, adhesion, and tumorigenesis. PMID: 21344397 Ref: GRB2 couples RhoU to epidermal growth factor receptor signaling and cell migration. PMID: 21508312 |
Ref: Murine colon proteome and characterization of the protein pathways. PMID: 22929016 Ref: miR-143 inhibits the metastasis of pancreatic cancer and an associated signaling pathway. PMID: 23070684 |
Ref: Expression profiles analysis of pancreatic cancer. PMID: 23426533 Ref: Saponins extracted from by-product of Asparagus officinalis L. suppress tumour cell migration and invasion through targeting Rho GTPase signalling pathway. PMID: 23450726 |
Ref: Palladin promotes invasion of pancreatic cancer cells by enhancing invadopodia formation in cancer-associated fibroblasts. PMID: 23524582 Ref: Vav1 as a central regulator of invadopodia assembly. PMID: 24332539 |
Ref: Targeting Pancreatic Cancer Metastasis by Inhibition of Vav1, a Driver of Tumor Cell Invasion. PMID: 25977335 |
Ref: Whole Genome Sequencing of Newly Established Pancreatic Cancer Lines Identifies Novel Somatic Mutation (c.2587G>A) in Axon Guidance Receptor Plexin A1 as Enhancer of Proliferation and Invasion. PMID: 26962861 Ref: ARHGEF15 overexpression worsens the prognosis in patients with pancreatic ductal adenocarcinoma through enhancing the motility and proliferative activity of the cancer cells. PMID: 27145964 Ref: Integrinbeta1 modulates tumour resistance to gemcitabine and serves as an independent prognostic factor in pancreatic adenocarcinomas. PMID: 27289231 Ref: Overexpression and biological function of IQGAP3 in human pancreatic cancer. PMID: 28078013 |
Ref: High Expression of Cell Division Cycle 42 Promotes Pancreatic Cancer Growth and Predicts Poor Outcome of Pancreatic Cancer Patients. PMID: 28181096 Ref: Discovery and characterization of small molecule Rac1 inhibitors. PMID: 28410221 Ref: Cdc42 Signaling Pathway Inhibition as a Therapeutic Target in Ras- Related Cancers. PMID: 28571533 Ref: Septin remodeling is essential for the formation of cell membrane protrusions (microtentacles) in detached tumor cells. PMID: 29100341 |
Ref: Multiplexed Real-Time NMR GTPase Assay for Simultaneous Monitoring of Multiple Guanine Nucleotide Exchange Factor Activities from Human Cancer Cells and Organoids. PMID: 29543440 Ref: Interleukin-6 promotes pancreatic cancer cell migration by rapidly activating the small GTPase CDC42. PMID: 29853638 Ref: ARHGEF4 predicts poor prognosis and promotes cell invasion by influencing ERK1/2 and GSK-3alpha/beta signaling in pancreatic cancer. PMID: 30226582 Ref: Novel Methylselenoesters Induce Programed Cell Death via Entosis in Pancreatic Cancer Cells. PMID: 30241340 Ref: Integrin beta1 promotes gemcitabine resistance in pancreatic cancer through Cdc42 activation of PI3K p110beta signaling. PMID: 30243721 |