Primary Site >> Colorectal Cancer
Gene >> CDC37
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Ref: Hyaluronan constitutively regulates ErbB2 phosphorylation and signaling complex formation in carcinoma cells. PMID: 15632176 |
Ref: Silencing the cochaperone CDC37 destabilizes kinase clients and sensitizes cancer cells to HSP90 inhibitors. PMID: 18931700 |
Ref: Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33. PMID: 22451720 |
Ref: Restricting direct interaction of CDC37 with HSP90 does not compromise chaperoning of client proteins. PMID: 24292678 Ref: Cks1 proteasomal degradation is induced by inhibiting Hsp90-mediated chaperoning in cancer cells. PMID: 25544127 |
Ref: Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922. PMID: 27391062 |
Ref: Cdc37 facilitates cell survival of colorectal carcinoma via activating the CDK4 signaling pathway. PMID: 29288563 |