Primary Site >> Colorectal Cancer
Gene >> CD8A
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Ref: Association of colorectal tumor epithelium expressing HLA-D/DR with CD8-positive T-cells and mononuclear phagocytes. PMID: 3105871 |
Ref: An 80 to 85 kilodalton human phosphoglycoprotein associated with cell activation. PMID: 3183379 |
Ref: Colonic lymphoid cell subsets and epithelial HLA-DR antigens in familial polyposis coli. PMID: 2558037 Ref: Characterization of activated lymphocytes in colon cancer. PMID: 2783402 |
Ref: Patterns of human tumor-infiltrating lymphocytes in 120 human cancers. PMID: 1689143 Ref: Effects of radiolabelled monoclonal antibody infusion on blood leukocytes in cancer patients. PMID: 1968968 Ref: Investigation of cytokine gene expression in human colorectal cancer. PMID: 2114216 |
Ref: Immunological effects of levamisole in vitro. PMID: 1790137 Ref: Immuno-chemotherapy of advanced colorectal cancer with alpha-2a interferon and 5-fluorouracil. Immunopharmacological studies. PMID: 1801883 Ref: Immunotherapy with IL2 by constant infusion and weekly doxorubicin. PMID: 1830717 Ref: Perforin expression in lymphocytes infiltrated to human colorectal cancer. PMID: 1892750 Ref: Monoclonal antibody-targeted superantigens: a different class of anti-tumor agents. PMID: 1924393 Ref: Changes in leucocyte populations following murine bifunctional antibody infusion in colon cancer patients. PMID: 2025955 Ref: Lymphocytopenia, T-lymphocyte subsets, and colorectal polyps in automotive pattern and model makers. PMID: 2037906 |
Ref: Establishment of cytotoxic CD4+ T cell clones from cancer patients treated by local immunotherapy. PMID: 1363274 Ref: Effect of anti-CD3 antibody on the generation of interleukin-2-activated lymphocytes from tumor tissues of gastrointestinal cancer. PMID: 1386555 Ref: Locally superantigen-activated peritoneal cytolytic T lymphocytes belong to the CD8+ CD45RC- subset and lyse MHC class II+ tumor cells. PMID: 1487309 Ref: [Significance of antitumor effects and immunological response on endogenously induced LAK therapy for primary or metastatic liver tumor]. PMID: 1530292 Ref: [Detection of endogenous IFN-gamma and TNF-alpha in tumor-infiltrating mononuclear cells of human colorectal cancer]. PMID: 1559660 Ref: An analysis of autologous T-cell anti-tumour responses in colon-carcinoma patients following active specific immunization (ASI). PMID: 1639535 Ref: Spontaneous cytotoxicity of human intraepithelial lymphocytes against epithelial cell tumors. PMID: 1727781 Ref: Shared human melanoma antigens. Recognition by tumor-infiltrating lymphocytes in HLA-A2.1-transfected melanomas. PMID: 1729379 |
Ref: Low-dose interleukin-2 in combination with interferon-alpha effectively modulates biological response in vivo. PMID: 7683166 Ref: The role of lymphocyte surface binding sites for wheat germ agglutinin in the negative regulation of cancer patients. PMID: 8219608 Ref: Hepatic arterial infusions of interleukin-2-based immunochemotherapy in the treatment of unresectable liver metastases from colorectal cancer. PMID: 8221817 Ref: Study of effect of surgical stress on immunity in patients with gastrointestinal cancer. PMID: 8274052 Ref: Characterization of the inflammatory cell populations in normal colon and colonic carcinomas. PMID: 8287117 Ref: Specific immune recognition of autologous tumor by lymphocytes infiltrating colon carcinomas: analysis by cytokine secretion. PMID: 8422663 Ref: Intestinal intraepithelial lymphocytes bind to colon cancer cells by HML-1 and CD11a. PMID: 8453630 Ref: [Characterization of autologous-tumor specific cytotoxic T cells induced by means of butanol-extracted soluble antigen from T lymphocytes in colon cancer patients]. PMID: 8464410 Ref: Inhibition of proliferation, activation and function of human natural-killer-cells in-vitro by secreted products of lovo, a colorectal-cancer cell-line. PMID: 21573430 |
Ref: Alteration in lymphocyte phenotype associated with administration of adjuvant levamisole and 5-fluorouracil. PMID: 7515770 Ref: A phase II study of advanced colorectal cancer patients treated with combination 5-fluorouracil plus leucovorin and subcutaneous interleukin-2 plus alpha interferon. PMID: 7830105 Ref: Secretion of human monoclonal antibody after fusion of an immortal T cell line and lymphocytes from the peripheral blood of a patient with colon carcinoma. PMID: 7858181 Ref: p21-ras-peptide-specific T-cell responses in a patient with colorectal cancer. CD4+ and CD8+ T cells recognize a peptide corresponding to a common mutation (13Gly-->Asp). PMID: 7903287 Ref: Binding of natural human IgM auto-antibodies to human tumor cell lines and stimulated normal T lymphocytes. PMID: 7912225 Ref: Effect of essential fatty acids on circulating T cell subsets in patients with colorectal cancer. PMID: 7954523 Ref: The effect of previous blood transfusion on lymphocyte subsets and natural killer cell function in patients with colorectal cancer. PMID: 7975450 Ref: Complete remission of liver metastases from colorectal cancer by treatment with a hepatic artery infusion (HAI) of interleukin-2-based immunochemotherapy: reports of three cases. PMID: 8054783 Ref: Phenotypical and functional characteristics of tumor-infiltrating lymphocytes from colon carcinomas stimulated with rIL-2 and rIL-4 in vitro: comparison with lymphocytes of the normal colon mucosa and the peripheral blood. PMID: 8074499 |
Ref: Clinical evidence that the human monoclonal anti-idiotypic antibody 105AD7, delays tumor growth by stimulating anti-tumor T-cell responses. PMID: 7492753 Ref: A novel co-stimulatory T cell antigen co-expressed on renal cell carcinoma. PMID: 7495750 Ref: Expression of adhesion molecules in the host response to colon carcinoma. PMID: 7540782 Ref: Colorectal cell line suppression of lymphokine activated killer cell generation is reversed by suramin. PMID: 7540893 Ref: Generation of human cytotoxic T cells specific for human carcinoembryonic antigen epitopes from patients immunized with recombinant vaccinia-CEA vaccine. PMID: 7629885 Ref: Morphological and functional characteristics of tumor-infiltrating lymphocytes from human colorectal cancers after stimulation with rIL-2. PMID: 7649213 Ref: Expansion of mucin-reactive T-helper lymphocytes from patients with colorectal cancer. PMID: 7663570 Ref: Tumor-associated glycoantigen, sialyl Lewis(a) as a target for bispecific antibody-directed adoptive tumor immunotherapy. PMID: 7721341 Ref: CD8+ T cells from a patient with colon carcinoma, specific for a mutant p21-Ras-derived peptide (Gly13-->Asp), are cytotoxic towards a carcinoma cell line harbouring the same mutation. PMID: 7728775 Ref: Polysaccharide preparation PSK augments the proliferation and cytotoxicity of tumor-infiltrating lymphocytes in vitro. PMID: 7762991 Ref: Alterations in the signal-transducing molecules of T cells and NK cells in colorectal tumor-infiltrating, gut mucosal and peripheral lymphocytes: correlation with the stage of the disease. PMID: 7790109 Ref: Phase I trial of escalating doses of interleukin-1 beta in combination with a fixed dose of interleukin-2. PMID: 7844609 Ref: Culture of tumour-infiltrating lymphocytes from melanoma and colon carcinoma: removal of tumour cells does not affect tumour-specificity. PMID: 8536275 Ref: Immunological alterations induced by adjuvant treatment of postoperative colon carcinoma Duke's B or C with levamisole in combination with 5-FU. PMID: 8572636 |
Ref: Lymphocyte subset infiltration patterns and HLA antigen status in colorectal carcinomas and adenomas. PMID: 8566865 Ref: DCC protein expression in hematopoietic cell populations and its relation to leukemogenesis. PMID: 8609244 Ref: Immune reactions induced by interleukin-2 transfected colorectal cancer cells in vitro: predominant induction of lymphokine-activated killer cells. PMID: 8834769 Ref: Phase II trial of intravenous endotoxin in patients with colorectal and non-small cell lung cancer. PMID: 8983279 Ref: Phenotypical and functional differences of tumor-infiltrating lymphocytes from human colorectal cancers induced by costimulation with rIL-2 and rIL-4 in vitro. PMID: 9042222 Ref: Necessity of biotherapeutic treatments inducing TH1 cell functions in colorectal cancer. PMID: 10851498 Ref: Immunological directives for biotherapy improvement in the treatment of colorectal cancer. PMID: 10851527 |
Ref: Infiltration of mononuclear inflammatory cells into primary colorectal carcinomas: an immunohistological analysis. PMID: 9020482 Ref: Biologic properties of a bispecific single-chain antibody directed against 17-1A (EpCAM) and CD3: tumor cell-dependent T cell stimulation and cytotoxic activity. PMID: 9103467 Ref: Carbohydrate recognition on MUC1-expressing targets enhances cytotoxicity of a T cell subpopulation. PMID: 9246205 Ref: Expression of costimulatory molecules B7-1 and B7-2 by macrophages along invasive margin of colon cancer: a possible antitumor immunity? PMID: 9314947 Ref: Construction and biological activity of a recombinant bispecific single-chain antibody designed for therapy of minimal residual colorectal cancer. PMID: 9435872 Ref: Generation of stable CD4+ and CD8+ T cell lines from patients immunized with ras oncogene-derived peptides reflecting codon 12 mutations. PMID: 9514698 Ref: Tumor localization by tumor infiltrating lymphocytes labeled with indium-111 in patients with metastatic renal cell carcinoma, melanoma, and colorectal cancer. PMID: 10851449 |
Ref: MHC class I bound peptides of a colon carcinoma cell line, a Ki-ras gene-targeted progeny cell line and a B cell line. PMID: 9489488 Ref: CD4- and TCRalphabeta-positive T lymphocytes predominantly infiltrated into well-moderately differentiated colon adenocarcinoma tissues. PMID: 9544823 Ref: Adoptive transfer: the role of perforin in mouse cytotoxic T lymphocyte rejection of human tumor xenografts in vivo. PMID: 9584828 Ref: T-cell evaluation in patients with colon cancer: dinitrochlorobenzene skin testing versus plasma levels of sIL-2r and sCD8. PMID: 9607619 Ref: [Preoperative treatment with interleukin-2 in colorectal carcinoma]. PMID: 9628067 Ref: Gene transfer of costimulatory molecules into a human colorectal cancer cell line: requirement of CD54, CD80 and class II MHC expression for enhanced immunogenicity. PMID: 9640250 Ref: Tumour necrosis factor-alpha enhances intraepithelial lymphocyte proliferation and migration. PMID: 9659158 Ref: Adjuvant adoptive immunotherapy with tumour-infiltrating lymphocytes and modulated doses of interleukin-2 in 22 patients with melanoma, colorectal and renal cancer, after radical metastasectomy, and in 12 advanced patients. PMID: 9671141 Ref: Laparoscopic-assisted vs. open surgery for colorectal cancer: comparative study of immune effects. PMID: 9678378 Ref: Mutated Ras peptides as vaccines in immunotherapy of cancer. PMID: 9704487 Ref: CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer. PMID: 9721846 Ref: Identification of a human CD8+ T lymphocyte neo-epitope created by a ras codon 12 mutation which is restricted by the HLA-A2 allele. PMID: 9732698 Ref: Phase-II randomized study of pre-operative IL-2 administration in operable NSCLC. PMID: 9733054 Ref: [Host reactions affect cancer progression]. PMID: 9742527 Ref: Comparison of the effects of various clinically applied mistletoe preparations on peripheral blood leukocytes. PMID: 9893935 Ref: [Overexpression of B7-1 amd B7-2 by LFA-1 positive lymphocytes in chronic inflammatory bowel diseases]. PMID: 14518246 |
Ref: Inhibitory effects of transforming growth factor-beta (TGF-beta) on certain functions of intraepithelial lymphocytes. PMID: 10193412 Ref: Lymphocyte subpopulations in patients with multiple primary tumors. PMID: 10223250 Ref: Significance of pre-treatment immunological parameters in colorectal cancer patients with unresectable metastases to the liver. PMID: 10228796 Ref: High prevalence of activated intraepithelial cytotoxic T lymphocytes and increased neoplastic cell apoptosis in colorectal carcinomas with microsatellite instability. PMID: 10362805 Ref: Functional expression of beta1 and beta2 integrins on tumor infiltrating lymphocytes (TILs) in colorectal cancer. PMID: 10433007 Ref: Immunohistochemical analysis of inflammation in primary sclerosing cholangitis. PMID: 10445798 Ref: Pathophysiologic significance of host reactions in human cancer tissue: desmoplasia and tumor immunity. PMID: 10458476 Ref: Functional down-regulation of beta1 and beta2 integrins of lamina propria lymphocytes (LPL) and tumor-infiltrating lymphocytes (TIL) in colorectal cancer patients. PMID: 10458690 Ref: Characterisation of tumour infiltrating lymphocytes and correlations with immunological surface molecules in colorectal cancer. PMID: 10505031 Ref: Effect of B7.1-transfected human colon cancer cells on the induction of autologous tumour-specific cytotoxic T cells. PMID: 10530496 Ref: Recognition of a shared human prostate cancer-associated antigen by nonclassical MHC-restricted CD8+ T cells. PMID: 10570328 Ref: [Clinical study on treatment of rectal carcinoma with Chinese herbal medicine and high dose fluorouracil emulsion via rectal infusion]. PMID: 11783207 |
Ref: 105Ad7 cancer vaccine stimulates anti-tumour helper and cytotoxic T-cell responses in colorectal cancer patients but repeated immunisations are required to maintain these responses. PMID: 10585589 Ref: Evidence for Fas counter attack in vivo from a study of colorectal cancer. PMID: 10601589 Ref: Limitations of CD44v6 amplification for the detection of tumour cells in the blood of colorectal cancer patients. PMID: 10755402 Ref: Differential role of Fas/Fas ligand interactions in cytolysis of primary and metastatic colon carcinoma cell lines by human antigen-specific CD8+ CTL. PMID: 10779805 Ref: Influence of interferon gamma on modulation of Fas expression by human colon carcinoma cells and their subsequent sensitivity to antigen-specific CD8+ cytotoxic T lymphocyte attack. PMID: 10941902 Ref: Infiltration of CD8+ T cells in non-small cell lung cancer is associated with dedifferentiation of cancer cells, but not with prognosis. PMID: 10946920 Ref: Docetaxel-induced lymphopenia in patients with solid tumors: a prospective phenotypic analysis. PMID: 11002234 Ref: [Isolation and phenotypic analysis of lamina propria mononuclear cells from colonoscopic biopsy specimens]. PMID: 12501634 |
Ref: Tumour infiltrating lymphocytes and apoptosis are independent features in colorectal cancer stratified according to microsatellite instability status. PMID: 11171826 Ref: Familial cancer: depressed NK-cell cytotoxicity in healthy and cancer affected members. PMID: 11299423 Ref: Randomized clinical trial of the effect of open versus laparoscopically assisted colectomy on systemic immunity in patients with colorectal cancer. PMID: 11412248 Ref: CD3+CD56+CD8+ cells demonstrating a suppressor T cell-like function in the peripheral blood of colon cancer patients. PMID: 11494036 Ref: Melanoma-Reactive CD8+ T cells recognize a novel tumor antigen expressed in a wide variety of tumor types. PMID: 11565834 Ref: Changes in T cell subsets, interleukin-6 and C-reactive protein after laparoscopic and open colorectal resection for malignancy. PMID: 11727135 Ref: A parathyroid-hormone-related-protein (PTH-rP)-specific cytotoxic T cell response induced by in vitro stimulation of tumour-infiltrating lymphocytes derived from prostate cancer metastases, with epitope peptide-loaded autologous dendritic cells and low-do PMID: 11742494 Ref: Treatment of human colon carcinoma cell lines with anti-neoplastic agents enhances their lytic sensitivity to antigen-specific CD8+ cytotoxic T lymphocytes. PMID: 11761438 Ref: Minimal costimulatory requirements for T cell priming and TH1 differentiation: activation of naive human T lymphocytes by tumor cells armed with bifunctional antibody constructs. PMID: 12747771 |
Ref: Mature dendritic cells make clusters with T cells in the invasive margin of colorectal carcinoma. PMID: 11748640 Ref: Proliferation of T-cell subsets that contact tumour cells in colorectal cancer. PMID: 11882037 Ref: Increased expression of CD40 ligand on activated T cells of patients with colon cancer. PMID: 11948126 Ref: Different occurrence of CD8+, CD45R0+, and CD68+ immune cells in regional lymph node metastases from colorectal cancer as potential prognostic predictors. PMID: 12018450 Ref: A short-term dietary supplementation of high doses of vitamin E increases T helper 1 cytokine production in patients with advanced colorectal cancer. PMID: 12060616 Ref: The role of CD8(+) T cells in immune responses to colorectal cancer. PMID: 12070710 Ref: Identification of an interferon-gamma-inducible carcinoembryonic antigen (CEA) CD8(+) T-cell epitope, which mediates tumor killing in CEA transgenic mice. PMID: 12208761 Ref: Effect of parenteral nutrition with L-arginine supplementation on postoperative immune function in patients with colorectal cancer. PMID: 12297482 Ref: Helicobacter pylori organisms induce expression of activation and apoptotic surface markers on human lymphocytes and AGS cells: a cytofluorimetric evaluation. PMID: 12510791 |
Ref: Prognostic significance of CD8+ T cell and macrophage peritumoral infiltration in colorectal cancer. PMID: 12579264 Ref: Prognostic value of the CD4+/CD8+ ratio of tumour infiltrating lymphocytes in colorectal cancer and HLA-DR expression on tumour cells. PMID: 12695859 Ref: CD103+ intraepithelial lymphocytes--a unique population in microsatellite unstable sporadic colorectal cancer. PMID: 12751377 Ref: Recombinant antigen expression on yeast surface (RAYS) for the detection of serological immune responses in cancer patients. PMID: 12828452 Ref: [Determination of four kinds of cell phenotypes of peripheral blood lymphocytes in patients with colorectal cancer]. PMID: 12866971 Ref: NKG2D engagement of colorectal cancer-specific T cells strengthens TCR-mediated antigen stimulation and elicits TCR independent anti-tumor activity. PMID: 12884870 Ref: Analysis of MICA gene transcripts in human rectal cancers. PMID: 12894536 Ref: The apoptosis inhibitor protein survivin induces tumor-specific CD8+ and CD4+ T cells in colorectal cancer patients. PMID: 12907624 Ref: Intestinal immune responses in wild-type and Apcmin/+ mouse, a model for colon cancer. PMID: 12941845 Ref: Vaccination with autologous tumor-derived heat-shock protein gp96 after liver resection for metastatic colorectal cancer. PMID: 12960108 Ref: Human tumor-derived heat shock protein 96 mediates in vitro activation and in vivo expansion of melanoma- and colon carcinoma-specific T cells. PMID: 14500642 Ref: Colon polyps and cytokines: emerging immunological mechanisms. PMID: 14502322 Ref: EphA2 as target of anticancer immunotherapy: identification of HLA-A*0201-restricted epitopes. PMID: 14679012 |
Ref: Immune system and prognosis in colorectal cancer: a detailed immunohistochemical analysis. PMID: 14968119 Ref: In vivo manipulation of dendritic cell migration and activation to elicit antitumour immunity. PMID: 15027495 Ref: Tumour T-lymphocyte subset infiltration and tumour recurrence following curative resection for colorectal cancer. PMID: 15028311 Ref: Anandamide is an endogenous inhibitor for the migration of tumor cells and T lymphocytes. PMID: 15034673 Ref: Tumour-infiltrating lymphocytes in colorectal cancer with microsatellite instability are activated and cytotoxic. PMID: 15048750 Ref: [Expression of leucocyte cell-surface antigens on colon cancer cell line HR8348]. PMID: 15067730 Ref: AIM-2: a novel tumor antigen is expressed and presented by human glioma cells. PMID: 15076139 Ref: Dendritic cells in colorectal cancer correlate with other tumor-infiltrating immune cells. PMID: 15197496 Ref: CD8+ cytotoxic T lymphocytes isolated from allogeneic healthy donors recognize HLA class Ia/Ib-associated renal carcinoma antigens with ubiquitous or restricted tissue expression. PMID: 15231579 Ref: Prognostic role of CD8+ tumor-infiltrating lymphocytes in stage III colorectal cancer with and without microsatellite instability. PMID: 15257543 Ref: Diverse populations of T cells with NK cell receptors accumulate in the human intestine in health and in colorectal cancer. PMID: 15259008 Ref: Adequate nourishment through total parenteral nutrition treatment may augment immune function in patients with colon cancer. PMID: 15325502 Ref: Intraepithelial CD8+ T-cell-count becomes a prognostic factor after a longer follow-up period in human colorectal carcinoma: possible association with suppression of micrometastasis. PMID: 15494715 Ref: Perioperative immunonutrition ameliorates the postoperative immune depression in patients with gastrointestinal system cancer (prospective clinical study in 42 patients). PMID: 15587331 |
Ref: T-cell receptor BV gene usage in colorectal carcinoma patients immunised with recombinant Ep-CAM protein or anti-idiotypic antibody. PMID: 15570423 Ref: Natural killer cells infiltrating colorectal cancer and MHC class I expression. PMID: 15607811 Ref: Chinese medical herbs for chemotherapy side effects in colorectal cancer patients. PMID: 15674951 Ref: The relationship between tumour T-lymphocyte infiltration, the systemic inflammatory response and survival in patients undergoing curative resection for colorectal cancer. PMID: 15700032 Ref: A potent immunogenic general cancer vaccine that targets survivin, an inhibitor of apoptosis proteins. PMID: 15746049 Ref: ABCE1, a member of ATP-binding cassette transporter gene, encodes peptides capable of inducing HLA-A2-restricted and tumor-reactive cytotoxic T lymphocytes in colon cancer patients. PMID: 15809757 Ref: Phase I study of immunization with dendritic cells modified with fowlpox encoding carcinoembryonic antigen and costimulatory molecules. PMID: 15837756 Ref: Allogeneic dendritomas induce anti-tumour immunity against metastatic colon cancer. PMID: 15853920 Ref: Selective infiltration of CCR5(+)CXCR3(+) T lymphocytes in human colorectal carcinoma. PMID: 15856455 Ref: Human colorectal cancer cells induce T-cell death through release of proapoptotic microvesicles: role in immune escape. PMID: 15940614 Ref: Induction of antigen-specific CD4- and CD8-mediated T-cell responses by fusions of autologous dendritic cells and metastatic colorectal cancer cells. PMID: 15945098 Ref: [Clinical research of intraperitoneal chemotherapy plus Shenmai Injection in treating advanced colorectal cancer]. PMID: 16009102 Ref: DNA-based vaccines activate innate and adaptive antitumor immunity by engaging the NKG2D receptor. PMID: 16040807 Ref: Phase I/II combined chemoimmunotherapy with carcinoembryonic antigen-derived HLA-A2-restricted CAP-1 peptide and irinotecan, 5-fluorouracil, and leucovorin in patients with primary metastatic colorectal cancer. PMID: 16115944 Ref: [Effect of laparoscopic radical operation on systemic immunity in patients with colorectal cancer]. PMID: 16224653 Ref: Dendritic cells fused with allogeneic colorectal cancer cell line present multiple colorectal cancer-specific antigens and induce antitumor immunity against autologous tumor cells. PMID: 16278414 Ref: CD8+, HLA-unrestricted, cytotoxic T-lymphocyte line against malignant melanoma. PMID: 16281981 Ref: Effector memory T cells, early metastasis, and survival in colorectal cancer. PMID: 16371631 Ref: Lymphocyte subsets in peripheral blood as prognostic factors in colorectal cancer. PMID: 17343340 |
Ref: Induction of cellular immune responses against carcinoembryonic antigen in patients with metastatic tumors after vaccination with altered peptide ligand-loaded dendritic cells. PMID: 16034561 Ref: MT110: a novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors. PMID: 16139892 Ref: Characterization of tumour-infiltrating lymphocytes and apoptosis in colitis-associated neoplasia: comparison with sporadic colorectal cancer. PMID: 16315333 Ref: Tumor-associated antigen recognized by the 22-1-1 monoclonal antibody encourages colorectal cancer progression under the scanty CD8+ T cells. PMID: 16428480 Ref: Effects of desialylation of ovine submaxillary gland mucin (OSM) on humoral and cellular immune responses to Tn and sialylated Tn. PMID: 16524255 Ref: Perioperative IFN-alpha to avoid surgically induced immune suppression in colorectal cancer patients. PMID: 16598674 Ref: Identification of a major histocompatibility complex class I-restricted T-cell epitope in the tumour-associated antigen, 5T4. PMID: 16630022 Ref: Activation and dramatically increased cytolytic activity of tumor specific T lymphocytes after radio-frequency ablation in patients with hepatocellular carcinoma and colorectal liver metastases. PMID: 16773688 Ref: Unexpected abundance of HLA class II presented peptides in primary renal cell carcinomas. PMID: 16857787 Ref: Preoperative granulocyte/macrophage colony-stimulating factor (GM-CSF) increases hepatic dendritic cell numbers and clustering with lymphocytes in colorectal cancer patients. PMID: 16920503 Ref: Ex-vivo analysis of CD8+ T cells infiltrating colorectal tumors identifies a major effector-memory subset with low perforin content. PMID: 16967323 Ref: Proliferating endothelial cells and leukocyte infiltration as prognostic markers in colorectal cancer. PMID: 17059898 Ref: Vascular endothelial growth factor blockade reduces intratumoral regulatory T cells and enhances the efficacy of a GM-CSF-secreting cancer immunotherapy. PMID: 17121902 Ref: Tumor infiltrating T lymphocytes in colorectal cancer: Tumor-selective activation and cytotoxic activity in situ. PMID: 17122624 Ref: Colon cancer and the immune system: the role of tumor invading T cells. PMID: 17143936 Ref: Enhancement of immunologic tumor regression by intratumoral administration of dendritic cells in combination with cryoablative tumor pretreatment and Bacillus Calmette-Guerin cell wall skeleton stimulation. PMID: 17189420 Ref: Gene expression analysis of tumor infiltrating lymphocyte markers in endometrial cancers indicates no significant increases in those cases with microsatellite instability. PMID: 17192060 |
Ref: Efficient tumor cell lysis mediated by a Bcl-X(L) specific T cell clone isolated from a breast cancer patient. PMID: 16850344 Ref: Increased expression of HSP70 by colon cancer cells is not always associated with access to the dendritic cell cross-presentation pathway. PMID: 17235439 Ref: A pilot study of CTLA-4 blockade after cancer vaccine failure in patients with advanced malignancy. PMID: 17289891 Ref: Modulation of CD103 expression on human colon carcinoma-specific CTL. PMID: 17312135 Ref: High-level expression of chemokine CXCL16 by tumor cells correlates with a good prognosis and increased tumor-infiltrating lymphocytes in colorectal cancer. PMID: 17510400 Ref: Soluble Ig-like transcript 3 inhibits tumor allograft rejection in humanized SCID mice and T cell responses in cancer patients. PMID: 17513794 Ref: Low TCR avidity and lack of tumor cell recognition in CD8(+) T cells primed with the CEA-analogue CAP1-6D peptide. PMID: 17564703 Ref: The T-box transcription factor eomesodermin controls CD8 T cell activity and lymph node metastasis in human colorectal cancer. PMID: 17566017 Ref: Identification and characterization of ErbB-3-binding protein-1 as a target for immunotherapy. PMID: 17641068 Ref: Tumor doubling time and local immune response to hepatic metastases from colorectal cancer. PMID: 17654526 Ref: Effect of perioperative allogeneic red blood cell transfusion on the immune-inflammatory response after colorectal cancer resection. PMID: 17671807 Ref: The importance of T-lymphocyte subsets on overall survival of colorectal and gastric cancer patients. PMID: 17768369 Ref: Chemokine receptors in cancer metastasis and cancer cell-derived chemokines in host immune response. PMID: 17894551 Ref: Characterization of antigen-specific immune responses induced by canarypox virus vaccines. PMID: 17947686 Ref: [Microsatellite instability and therapeutic sensitivity]. PMID: 18314604 |
Ref: Enhancement of anti-tumor activity in vitro and in vivo by CD150 and SAP. PMID: 17692919 Ref: Human tankyrases are aberrantly expressed in colon tumors and contain multiple epitopes that induce humoral and cellular immune responses in cancer patients. PMID: 18026951 Ref: Multimarker phenotype predicts adverse survival in patients with lymph node-negative colorectal cancer. PMID: 18076013 Ref: Distinct CD8+ T cell repertoires primed with agonist and native peptides derived from a tumor-associated antigen. PMID: 18209048 Ref: Dissection of spontaneous cytotoxicity by human intestinal intraepithelial lymphocytes: MIC on colon cancer triggers NKG2D-mediated lysis through Fas ligand. PMID: 18284469 Ref: Preoperative treatment with a non-steroidal anti-inflammatory drug (NSAID) increases tumor tissue infiltration of seemingly activated immune cells in colorectal cancer. PMID: 18307280 Ref: Reverse transcriptase inhibitors induce cell differentiation and enhance the immunogenic phenotype in human renal clear-cell carcinoma. PMID: 18351578 Ref: Disrupted expression of CXCL5 in colorectal cancer is associated with rapid tumor formation in rats and poor prognosis in patients. PMID: 18413816 Ref: Impact of postoperative omega-3 fatty acid-supplemented parenteral nutrition on clinical outcomes and immunomodulations in colorectal cancer patients. PMID: 18416476 Ref: Detection and functional analysis of tumor infiltrating T-lymphocytes (TIL) in liver metastases from colorectal cancer. PMID: 18521684 Ref: Dysregulation in immune functions is reflected in tumor cell cytotoxicity by peripheral blood mononuclear cells from head and neck squamous cell carcinoma patients. PMID: 18547033 Ref: Local recurrence in mismatch repair-proficient colon cancer predicted by an infiltrative tumor border and lack of CD8+ tumor-infiltrating lymphocytes. PMID: 18559598 Ref: Primary CD56+ NK/T-cell lymphoma of the rectum accompanied with refractory ulcerative colitis. PMID: 18648746 Ref: T-cell responses to survivin in cancer patients undergoing radiation therapy. PMID: 18676762 Ref: Induction of both CD8+ and CD4+ T-cell-mediated responses in colorectal cancer patients by colon antigen-1. PMID: 18974390 Ref: High density of FOXP3-positive T cells infiltrating colorectal cancers with microsatellite instability. PMID: 18985040 Ref: Two-marker protein profile predicts poor prognosis in patients with early rectal cancer. PMID: 18985041 Ref: Leptin receptor-related immune response in colorectal tumors: the role of colonocytes and interleukin-8. PMID: 19010917 Ref: Intrarectal vaccination with recombinant vaccinia virus expressing carcinoembronic antigen induces mucosal and systemic immunity and prevents progression of colorectal cancer. PMID: 19018004 |
Ref: MSI-H colorectal cancers preferentially retain and expand intraepithelial lymphocytes rather than peripherally derived CD8+ T cells. PMID: 18488217 Ref: Decline of T cell-related immune functions in cancer patients and an attempt to restore them through infusion of activated autologous T cells. PMID: 18555517 Ref: Aberrant expression of the hematopoietic-restricted minor histocompatibility antigen LRH-1 on solid tumors results in efficient cytotoxic T cell-mediated lysis. PMID: 18719914 Ref: New time-dependent approach to analyse the prognostic significance of immunohistochemical biomarkers in colon cancer and diffuse large B-cell lymphoma. PMID: 18977805 Ref: Identification of CD8+CD25+Foxp3+ suppressive T cells in colorectal cancer tissue. PMID: 19022917 Ref: Tumor-infiltrating FOXP3+ T regulatory cells show strong prognostic significance in colorectal cancer. PMID: 19064967 Ref: TNK cells (NKG2D+ CD8+ or CD4+ T lymphocytes) in the control of human tumors. PMID: 19089424 Ref: Characterization of genetically modified T-cell receptors that recognize the CEA:691-699 peptide in the context of HLA-A2.1 on human colorectal cancer cells. PMID: 19118044 Ref: Lymphocyte recruitment into the tumor site is altered in patients with MSI-H colon cancer. PMID: 19165625 Ref: Activation of tumor-specific T lymphocytes after laser-induced thermotherapy in patients with colorectal liver metastases. PMID: 19184001 Ref: T cell-mediated immunoregulation in the gastrointestinal tract. PMID: 19210347 Ref: The localization and density of immune cells in primary tumors of human metastatic colorectal cancer shows an association with response to chemotherapy. PMID: 19226101 Ref: Enrichment of human CD4+ V(alpha)24/Vbeta11 invariant NKT cells in intrahepatic malignant tumors. PMID: 19342695 Ref: Identification of an immunogenic HLA-A*0201-binding T-cell epitope of the transcription factor PAX2. PMID: 19342968 Ref: Potent control of tumor growth by CEA/CD3-bispecific single-chain antibody constructs that are not competitively inhibited by soluble CEA. PMID: 19342971 Ref: IL4Ralpha+ myeloid-derived suppressor cell expansion in cancer patients. PMID: 19414811 Ref: Critical role for CD8+FoxP3+ regulatory T cells in colon cancer immune response in humans. PMID: 19433592 Ref: [Effect of enterosorption on immunologic parameters of patients with colorectal cancer in the postoperative period]. PMID: 19435203 Ref: Colorectal carcinomas in MUTYH-associated polyposis display histopathological similarities to microsatellite unstable carcinomas. PMID: 19527492 Ref: T cell infiltrate predicts long-term survival following resection of colorectal cancer liver metastases. PMID: 19568816 Ref: Correlation of cyclooxygenase 2 expression and inflammatory cells infiltration in colorectal cancer. PMID: 19579928 Ref: [Effect of Shenqi Fuzheng injection combined with chemotherapy in treating advanced colorectal carcinoma]. PMID: 19673337 Ref: CD8+ lymphocytes/ tumour-budding index: an independent prognostic factor representing a 'pro-/anti-tumour' approach to tumour host interaction in colorectal cancer. PMID: 19755986 Ref: In situ cytotoxic and memory T cells predict outcome in patients with early-stage colorectal cancer. PMID: 19858404 Ref: The prognostic significance of peripheral T-lymphocyte subsets and natural killer cells in patients with colorectal cancer. PMID: 19950782 Ref: Invasive front of colorectal cancer: dynamic interface of pro-/anti-tumor factors. PMID: 20014453 Ref: Decrease in intrahepatic CD56+ lymphocytes in gastric and colorectal cancer patients with liver metastases. PMID: 20078551 |
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