Primary Site >> Colorectal Cancer
Gene >> CD68
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Tumor infiltrating cells in human cancer. On the possible role of CD16+ macrophages in antitumor cytotoxicity. PMID: 1501443 |
Ref: Stromal expression of platelet-derived growth factor beta-receptor and platelet-derived growth factor B-chain in colorectal cancer. PMID: 8264231 Ref: Characterization of the inflammatory cell populations in normal colon and colonic carcinomas. PMID: 8287117 |
Ref: Expression of adhesion molecules in the host response to colon carcinoma. PMID: 7540782 |
Ref: Platelet-derived endothelial cell growth factor in human colon cancer angiogenesis: role of infiltrating cells. PMID: 8757194 |
Ref: Expression of costimulatory molecules B7-1 and B7-2 by macrophages along invasive margin of colon cancer: a possible antitumor immunity? PMID: 9314947 |
Ref: Significance of platelet-derived endothelial cell growth factor in the angiogenesis of human gastric cancer. PMID: 9516932 Ref: Immunopathology of metastases in patients of colorectal carcinoma treated with monoclonal antibody 17-1A and granulocyte macrophage colony-stimulating factor. PMID: 9717820 Ref: [Overexpression of B7-1 amd B7-2 by LFA-1 positive lymphocytes in chronic inflammatory bowel diseases]. PMID: 14518246 |
Ref: Mast cell sarcoma with tissue eosinophilia arising in the ascending colon. PMID: 10430280 Ref: Up-regulation of macrophage wnt gene expression in adenoma-carcinoma progression of human colorectal cancer. PMID: 10507776 |
Ref: Localization of cyclooxygenase-2 in human sporadic colorectal adenomas. PMID: 10666384 Ref: Epithelioid leiomyosarcoma with osteoclast-like giant cells in the rectum. PMID: 10705403 Ref: Clinicopathologic significance of urokinase receptor- and MMP-9-positive stromal cells in human colorectal cancer: functional multiplicity of matrix degradation on hematogenous metastasis. PMID: 10728590 |
Ref: Morphometric analysis of liver macrophages in patients with colorectal liver metastasis. PMID: 11964075 Ref: Different occurrence of CD8+, CD45R0+, and CD68+ immune cells in regional lymph node metastases from colorectal cancer as potential prognostic predictors. PMID: 12018450 Ref: Characterization of structures with T-lymphocyte aggregates in ileal villi of Crohn's disease. PMID: 12135029 Ref: Relationships between tumor-associated macrophages and clinicopathological factors in patients with colorectal cancer. PMID: 12553072 |
Ref: Vascular endothelial growth factor, CD68, and epidermal growth factor receptor expression and survival in patients with Stage II and Stage III colon carcinoma: a role for the host response in prognosis. PMID: 12569594 Ref: Prognostic significance of CD8+ T cell and macrophage peritumoral infiltration in colorectal cancer. PMID: 12579264 Ref: Expression of cyclooxygenase-2 in human hyperplastic gastric polyps. PMID: 14582702 |
Ref: Expression of thymidine phosphorylase by macrophages in colorectal cancer tissues. PMID: 14966914 Ref: Platelet-derived endothelial cell growth factor expression is an independent prognostic factor in colorectal cancer patients after curative surgery. PMID: 15028312 Ref: Breast adenocarcinoma liver metastases, in contrast to colorectal cancer liver metastases, display a non-angiogenic growth pattern that preserves the stroma and lacks hypoxia. PMID: 15054467 Ref: [Thymidine phosphorylase expressed in monocyte-macrophages enhanced anticancer effect of 5'-deoxy-5-fluorouridine on colorectal carcinoma cells]. PMID: 15200906 Ref: Prognostic relevance of tumour-associated macrophages and von Willebrand factor-positive microvessels in colorectal cancer. PMID: 15232739 Ref: A novel method for isolation of endothelial cells and macrophages from murine tumors based on Ac-LDL uptake and CD16 expression. PMID: 15627623 |
Ref: Localization of tissue inhibitor of metalloproteinases 1 (TIMP-1) in human colorectal adenoma and adenocarcinoma. PMID: 15386409 Ref: Progressive loss of endothelial P-selectin expression with increasing malignancy in colorectal cancer. PMID: 15640834 Ref: Importance of thymidine phosphorylase expression in tumor stroma as a prognostic factor in patients with advanced colorectal carcinoma. PMID: 15706408 Ref: Association between cyclooxygenase-2-expressing macrophages, ulceration and microvessel density in colorectal cancer. PMID: 15720414 Ref: Relationship between interleukin-12-expressing cells and antigen-presenting cells in patients with colorectal cancer. PMID: 16101177 |
Ref: Increased activity of matrix metalloproteinase 2 and 9 after hepatic radiofrequency ablation. PMID: 16934296 Ref: Proliferating endothelial cells and leukocyte infiltration as prognostic markers in colorectal cancer. PMID: 17059898 Ref: [Influence of tumor-associated macrophages on progression and prognosis of nasopharyngeal carcinoma]. PMID: 17094898 |
Ref: Activation of human peritoneal immune cells in early stages of gastric and colon cancer. PMID: 17263978 Ref: High macrophage infiltration along the tumor front correlates with improved survival in colon cancer. PMID: 17332291 Ref: Soluble Ig-like transcript 3 inhibits tumor allograft rejection in humanized SCID mice and T cell responses in cancer patients. PMID: 17513794 Ref: TGF-beta receptor 2 downregulation in tumour-associated stroma worsens prognosis and high-grade tumours show more tumour-associated macrophages and lower TGF-beta1 expression in colon carcinoma: a retrospective study. PMID: 17692120 Ref: Endothelial cells of human colorectal cancer and healthy colon reveal phenotypic differences in culture. PMID: 17876298 Ref: Tumor-infiltrating macrophages and dendritic cells in human colorectal cancer: relation to local regulatory T cells, systemic T-cell response against tumor-associated antigens and survival. PMID: 18047662 |
Ref: Toll-like receptor 5 engagement modulates tumor development and growth in a mouse xenograft model of human colon cancer. PMID: 18538140 |
Ref: Macrophage-derived interleukin-6 up-regulates MUC1, but down-regulates MUC2 expression in the human colon cancer HT-29 cell line. PMID: 19201396 Ref: Radiation-induced thymidine phosphorylase upregulation in rectal cancer is mediated by tumor-associated macrophages by monocyte chemoattractant protein-1 from cancer cells. PMID: 19215821 Ref: Significance of monocyte chemoattractant protein-1 in angiogenesis and survival in colorectal liver metastases. PMID: 19287949 Ref: Association of inflammation-related and microRNA gene expression with cancer-specific mortality of colon adenocarcinoma. PMID: 19737943 |
Ref: Role of TGF-beta1, its receptor TGFbetaRII, and Smad proteins in the progression of colorectal cancer. PMID: 20165854 Ref: Immunohistochemical study of colorectal cancer liver metastases: the immune/inflammatory infiltrate. PMID: 20191123 Ref: Increased osteopontin-positive macrophage expression in colorectal cancer stroma with synchronous liver metastasis. PMID: 20414778 Ref: Putative contribution of CD56 positive cells in cetuximab treatment efficacy in first-line metastatic colorectal cancer patients. PMID: 20591136 Ref: Characterization of rectal, proximal and distal colon cancers based on clinicopathological, molecular and protein profiles. PMID: 20664940 Ref: Intratumoral macrophage counts correlate with tumor progression in colorectal cancer. PMID: 20740582 Ref: Macrophages may promote cancer growth via a GM-CSF/HB-EGF paracrine loop that is enhanced by CXCL12. PMID: 20946648 Ref: The tumor microenvironment of colorectal cancer: stromal TLR-4 expression as a potential prognostic marker. PMID: 21059221 Ref: TIA-1 cytotoxic granule-associated RNA binding protein improves the prognostic performance of CD8 in mismatch repair-proficient colorectal cancer. PMID: 21179245 |
Ref: The melatonin action on stromal stem cells within pericryptal area in colon cancer model under constant light. PMID: 21266165 Ref: IL-17 is associated with poor prognosis and promotes angiogenesis via stimulating VEGF production of cancer cells in colorectal carcinoma. PMID: 21396350 Ref: Expression of macrophage antigens by tumor cells. PMID: 21506012 Ref: Isolation of endothelial cells from human tumors. PMID: 21516410 Ref: Infiltration of CD14-positive macrophages at the invasive front indicates a favorable prognosis in colorectal cancer patients with lymph node metastasis. PMID: 21661395 Ref: Activation of tumor-promoting type 2 macrophages by EGFR-targeting antibody cetuximab. PMID: 21788356 Ref: Oncolytic herpes virus induces effective anti-cancer immunity against murine colon cancer. PMID: 21940320 Ref: Characterization of the immunological microenvironment of tumour buds and its impact on prognosis in mismatch repair-proficient and -deficient colorectal cancers. PMID: 22034888 Ref: Osteopontin induced by macrophages contribute to metachronous liver metastases in colorectal cancer. PMID: 22196667 |
Ref: Myeloperoxidase immunohistochemistry as a measure of disease activity in ulcerative colitis: association with ulcerative colitis-colorectal cancer, tumor necrosis factor polymorphism and RUNX3 methylation. PMID: 21425209 Ref: A high-fat diet increases angiogenesis, solid tumor growth, and lung metastasis of CT26 colon cancer cells in obesity-resistant BALB/c mice. PMID: 21919080 Ref: Type and location of tumor-infiltrating macrophages and lymphatic vessels predict survival of colorectal cancer patients. PMID: 21952788 Ref: Activated macrophages containing tumor marker in colon carcinoma: immunohistochemical proof of a concept. PMID: 22134871 Ref: The role of myofibroblasts in upregulation of S100A8 and S100A9 and the differentiation of myeloid cells in the colorectal cancer microenvironment. PMID: 22634002 Ref: Prognostic impact of beta-2-microglobulin expression in colorectal cancers stratified by mismatch repair status. PMID: 22859396 Ref: Sequential metastases of colorectal cancer: Immunophenotypes and spatial distributions of infiltrating immune cells in relation to time and treatments. PMID: 22934251 |
Ref: Reciprocal interactions between tumor-associated macrophages and CD44-positive cancer cells via osteopontin/CD44 promote tumorigenicity in colorectal cancer. PMID: 23251004 Ref: Tumor budding, myofibroblast proliferation, and fibrosis in obstructing colon carcinoma: the roles of Hsp47 and basic fibroblast growth factor. PMID: 23265436 Ref: Correlations of tumor-associated macrophage subtypes with liver metastases of colorectal cancer. PMID: 23621176 Ref: CD169-positive macrophages in regional lymph nodes are associated with a favorable prognosis in patients with colorectal carcinoma. PMID: 23734742 Ref: The density of macrophages in colorectal cancer is inversely correlated to TGF-beta1 expression and patients' survival. PMID: 23801404 Ref: Extranodal rosai-dorfman disease associated with increased numbers of immunoglobulin g4 plasma cells involving the colon: case report with literature review. PMID: 23808473 Ref: Crosstalk between colon cancer cells and macrophages via inflammatory mediators and CD47 promotes tumour cell migration. PMID: 23810249 Ref: Tumour-infiltrating CD68+ and CD57+ cells predict patient outcome in stage II-III colorectal cancer. PMID: 23868006 Ref: Digital pattern recognition-based image analysis quantifies immune infiltrates in distinct tissue regions of colorectal cancer and identifies a metastatic phenotype. PMID: 23963148 Ref: Identification of miR-30e* regulation of Bmi1 expression mediated by tumor-associated macrophages in gastrointestinal cancer. PMID: 24312366 |
Ref: Endoscopic mucosal resection of a rectal malakoplakia in a healthy adult. PMID: 24373062 Ref: Macrophage expression of tartrate-resistant acid phosphatase as a prognostic indicator in colon cancer. PMID: 24429833 Ref: Immune escape mechanisms in colorectal cancer pathogenesis and liver metastasis. PMID: 24741617 Ref: Tumor-associated macrophage-derived IL-6 and IL-8 enhance invasive activity of LoVo cells induced by PRL-3 in a KCNN4 channel-dependent manner. PMID: 24885636 Ref: Macrophage profile in primary versus secondary liver tumors. PMID: 25007179 |
Ref: Tumor Budding Correlates With the Protumor Immune Microenvironment and Is an Independent Prognostic Factor for Recurrence of Stage I Lung Adenocarcinoma. PMID: 25836013 Ref: Inflammation and uPAR-Expression in Colorectal Liver Metastases in Relation to Growth Pattern and Neo-adjuvant Therapy. PMID: 26268716 Ref: Can macrophages within the microenvironment of locally invasive rectal cancers predict response to radiotherapy? PMID: 26312909 Ref: Evaluation of immune cell markers in tumor tissue treated with radioimmunotherapy in an immunocompetent rat colon carcinoma model. PMID: 26374556 Ref: Cancer-related CD15/FUT4 overexpression decreases benefit to agents targeting EGFR or VEGF acting as a novel RAF-MEK-ERK kinase downstream regulator in metastatic colorectal cancer. PMID: 26427914 Ref: Tumor-Associated Macrophage (TAM) and Angiogenesis in Human Colon Carcinoma. PMID: 27275223 |
Ref: Netrin-1 is highly expressed and required in inflammatory infiltrates in wear particle-induced osteolysis. PMID: 26452536 Ref: The Fractalkine-Receptor Axis Improves Human Colorectal Cancer Prognosis by Limiting Tumor Metastatic Dissemination. PMID: 26673138 Ref: Effects of autophagy regulation of tumor-associated macrophages on radiosensitivity of colorectal cancer cells. PMID: 26821367 Ref: The relationships between serum cytokine levels and tumor infiltrating immune cells and their clinical significance in colorectal cancer. PMID: 26874795 Ref: Chronic ethanol feeding promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis potentially by enhancing mucosal inflammation. PMID: 26951793 Ref: Cancer-Associated Immune Resistance and Evasion of Immune Surveillance in Colorectal Cancer. PMID: 27006653 Ref: Phenotyping of tumor-associated macrophages in colorectal cancer: Impact on single cell invasion (tumor budding) and clinicopathological outcome. PMID: 27141391 Ref: Myenteric plexuses atrophy in the vicinity of colorectal cancer tissue is not caused by apoptosis or necrosis. PMID: 27439439 Ref: The Immune Landscapes of Polypoid and Nonpolypoid Precancerous Colorectal Lesions. PMID: 27441558 Ref: Immune Architecture of Colorectal Lung Metastases and Implications for Patient Survival. PMID: 27441643 |
Ref: Tumor-Associated Macrophage Infiltration in Colorectal Cancer Liver Metastases is Associated With Better Outcome. PMID: 28213791 Ref: The PD-1 expressing immune phenotype of T cell exhaustion is prominent in the 'immunoreactive' microenvironment of colorectal carcinoma. PMID: 28383777 Ref: Vascular endothelial growth factor A amplification in colorectal cancer is associated with reduced M1 and M2 macrophages and diminished PD-1-expressing lymphocytes. PMID: 28403223 Ref: Intratumoral Fusobacterium nucleatum abundance correlates with macrophage infiltration and CDKN2A methylation in microsatellite-unstable colorectal carcinoma. PMID: 28597080 Ref: The Immune-microenvironment Confers Chemoresistance of Colorectal Cancer through Macrophage-Derived IL6. PMID: 28928161 Ref: Tumor-associated macrophages and response to 5-fluorouracil adjuvant therapy in stage III colorectal cancer. PMID: 29209561 |
Ref: Nuclear factor E2-related factor-2 has a differential impact on MCT1 and MCT4 lactate carrier expression in colonic epithelial cells: a condition favoring metabolic symbiosis between colorectal cancer and stromal cells. PMID: 28846107 Ref: A novel histological examination with dynamic three-dimensional reconstruction from multiple immunohistochemically stained sections of a PD-L1-positive colon cancer. PMID: 28940664 Ref: Partial to complete abrogation of the subepithelial macrophage barrier against the gut microbiota in patients with ulcerative colitis and Crohn's colitis. PMID: 29023984 Ref: Clinical significance of programmed cell death-ligand 1 expression and the immune microenvironment at the invasive front of colorectal cancers with high microsatellite instability. PMID: 29044503 Ref: Mismatch repair-deficient colorectal cancer: a model of immunogenic and immune cell-rich tumor despite nonsignificant programmed cell death ligand-1 expression in tumor cells. PMID: 29208565 Ref: Tumor-associated macrophages remodeling EMT and predicting survival in colorectal carcinoma. PMID: 29416940 Ref: Mast cells co-expressing CD68 and inorganic polyphosphate are linked with colorectal cancer. PMID: 29543850 Ref: Expression and location of IL-17A, E, F and their receptors in colorectal adenocarcinoma: Comparison with benign intestinal disease. PMID: 29548809 Ref: [Effect and mechanism of antimicrobial peptide cathelicidin secreted by tumor associated macrophage on the growth of colorectal cancer in mice]. PMID: 29575834 Ref: Bidirectional Regulation of COX-2 Expression Between Cancer Cells and Macrophages. PMID: 29715103 Ref: The distribution of intratumoral macrophages correlates with molecular phenotypes and impacts prognosis in colorectal carcinoma. PMID: 29906313 Ref: Cancer Stemness, Immune Cells, and Epithelial-Mesenchymal Transition Cooperatively Predict Prognosis in Colorectal Carcinoma. PMID: 29921496 Ref: Appearance of ductal breast and colon carcinoma with gastrointestinal stromal tumor (GIST) in a female patient: an extremely rare case. PMID: 30173272 Ref: Colon cancer-derived conditioned medium induces differentiation of THP-1 monocytes into a mixed population of M1/M2 cells. PMID: 30183516 Ref: Assessment of intratumor immune-microenvironment in colorectal cancers with extranodal extension of nodal metastases. PMID: 30202242 Ref: PMA treated THP-1-derived-IL-6 promotes EMT of SW48 through STAT3/ERK-dependent activation of Wnt/beta-catenin signaling pathway. PMID: 30243096 |