Primary Site >> Colorectal Cancer

Gene >> CD46

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Ref: Tumor localization by combinations of monoclonal antibodies in a new human colon carcinoma cell line (LIM1899).
PMID: 2386931
Ref: Expression of CD59, a complement regulator protein and a second ligand of the CD2 molecule, and CD46 in normal and neoplastic colorectal epithelium.
PMID: 7692919
Ref: Distribution of complement regulatory proteins, decay-accelerating factor, CD59/homologous restriction factor 20 and membrane cofactor protein in human colorectal adenoma and cancer.
PMID: 7532345
Ref: Human carcinomas variably express the complement inhibitory proteins CD46 (membrane cofactor protein), CD55 (decay-accelerating factor), and CD59 (protectin).
PMID: 8686736
Ref: The complement regulatory proteins CD46 and CD59, but not CD55, are highly expressed by glandular epithelium of human breast and colorectal tumour tissues.
PMID: 9808413
Ref: Expression and regulation by interferon-gamma of the membrane-bound complement regulators CD46 (MCP), CD55 (DAF) and CD59 in gastrointestinal tumours.
PMID: 10211099
Ref: Immunization against tumor cell surface complement-regulatory proteins.
PMID: 11757799
Ref: In vivo manipulation of dendritic cell migration and activation to elicit antitumour immunity.
PMID: 15027495
Ref: Dexamethasone modifies the susceptibility to serum cytotoxicity and increases the metastatic efficiency of a colon carcinoma cell line.
PMID: 16380115
Ref: Cell-surface density of complement restriction factors (CD46, CD55, and CD59): oral squamous cell carcinoma versus other solid tumors.
PMID: 17234541
Ref: In vitro and in vivo synergy of MCP compounds with mitogen-activated protein kinase pathway- and microtubule-targeting inhibitors.
PMID: 17363484
Ref: Role of complement regulatory proteins in the survival of murine allo-transplanted Sertoli cells.
PMID: 17449937
Ref: Micropatterned surfaces to study hyaluronic acid interactions with cancer cells.
PMID: 21206473
Ref: Transduction and oncolytic profile of a potent replication-competent adenovirus 11p vector (RCAd11pGFP) in colon carcinoma cells.
PMID: 21455297
Ref: A two-hybrid approach to identify inhibitors of the RAS-RAF interaction.
PMID: 25033807
Ref: CD55 limits sensitivity to complement-dependent cytolysis triggered by heterologous expression of alpha-gal xenoantigen in colon tumor cells.
PMID: 24763553
Ref: Systematic immunohistochemical analysis of the expression of CD46, CD55, and CD59 in colon cancer.
PMID: 24978917
Ref: Adverse histological features in malignant colorectal polyps: a contemporary series of 239 cases.
PMID: 26424814
Ref: Efficacy of CD46-targeting chimeric Ad5/35 adenoviral gene therapy for colorectal cancers.
PMID: 27203670
Ref: Transcriptomic analysis of the tumor microenvironment to guide prognosis and immunotherapies.
PMID: 28884365